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anti scl 70 antibody
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what is 'anti scl 70 antibody'?
Definition for anti SCl 70 antibody
antibody seen in certain collagen vascular diseases
anti SCl 70 antibody is also known as: anti SCl 70 antibody, anti topoisomerase 1 antibody, anti topoisomerase antibody
anti SCl 70 antibody is a medical procedure used for such diagnoses as: CREST Syndrome, Sjogren's Syndrome and scleroderma.
related diagnosis for 'anti scl 70 antibody'
1 - 4 of
4
diagnosis
CREST Syndrome
variant of scleroderma with limited manifestations
anti SCl 70 antibody and CREST Syndrome
Sjogren's Syndrome
multisystem auto immune disease that also affects tear and salivary glands
anti SCl 70 antibody and Sjogren's Syndrome
scleroderma
multisystem disease with increased collagen deposits
anti SCl 70 antibody and scleroderma
systemic lupus erythematosis
multisystem connective tissue autoimmune disease
anti SCl 70 antibody and systemic lupus erythematosis
related procedure for 'anti scl 70 antibody'/associated diagnoses
1 - 5 of
118
procedures
Complete Blood Count
anti SCl 70 antibody and Complete Blood Count
CT scan
anti SCl 70 antibody and CT scan
Anticentromere antibodies
antibodies in certain collagen vascular diseases
anti SCl 70 antibody and Anticentromere antibodies
Barium Swallow
anti SCl 70 antibody and Barium Swallow
Esophagogastroduodenoscopy (EGD)
anti SCl 70 antibody and Esophagogastroduodenoscopy (EGD)
Fluoroscopy
anti SCl 70 antibody and Fluoroscopy
fluoroscopic esophagogram
anti SCl 70 antibody and fluoroscopic esophagogram
Anti-single stranded DNA antibodies (anti-ssDNA)
anti SCl 70 antibody and Anti-single stranded DNA antibodies (anti-ssDNA)
BUN
anti SCl 70 antibody and BUN
Erythrocyte Sedimentation Rate (ESR)
anti SCl 70 antibody and Erythrocyte Sedimentation Rate (ESR)
Serum Creatinine
anti SCl 70 antibody and Serum Creatinine
Single-Stranded (ss)-DNA Antibody
anti SCl 70 antibody and Single-Stranded (ss)-DNA Antibody
indirect immunofluorescence (IIF)
anti SCl 70 antibody and indirect immunofluorescence (IIF)
Antinuclear Antibody (ANA) homogenous pattern
antinuclear antibody homogenous pattern
anti SCl 70 antibody and Antinuclear Antibody (ANA) homogenous pattern
Antinuclear Antibody (ANA) speckled pattern
Antinuclear Antibody speckled pattern
anti SCl 70 antibody and Antinuclear Antibody (ANA) speckled pattern
Chest X-ray
Radiological technique to image the chest
anti SCl 70 antibody and Chest X-ray
Antinuclear Antibody (ANA)
Antinuclear antibody blood test used to screen for autoimmune disorders
anti SCl 70 antibody and Antinuclear Antibody (ANA)
C Reactive Protein (CRP)
anti SCl 70 antibody and C Reactive Protein (CRP)
Serum calcium
anti SCl 70 antibody and Serum calcium
CT subcutaneous tissues
anti SCl 70 antibody and CT subcutaneous tissues
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related medication for 'anti scl 70 antibody'/associated diagnoses
1 - 5 of
118
drugs
cilostazol
anti SCl 70 antibody and cilostazol
cyclophosphamide
anti SCl 70 antibody and cyclophosphamide
alendronate
anti SCl 70 antibody and alendronate
alprostadil
anti SCl 70 antibody and alprostadil
aluminum hydroxide
anti SCl 70 antibody and aluminum hydroxide
colchicine
anti SCl 70 antibody and colchicine
etidronate
anti SCl 70 antibody and etidronate
famotidine
anti SCl 70 antibody and famotidine
fluoxetine
anti SCl 70 antibody and fluoxetine
iloprost
anti SCl 70 antibody and iloprost
lansoprazole
anti SCl 70 antibody and lansoprazole
losartan
anti SCl 70 antibody and losartan
minocycline
anti SCl 70 antibody and minocycline
nicardipine
anti SCl 70 antibody and nicardipine
nifedipine
anti SCl 70 antibody and nifedipine
nitroglycerin
anti SCl 70 antibody and nitroglycerin
nizatidine
anti SCl 70 antibody and nizatidine
omeprazole
anti SCl 70 antibody and omeprazole
probenecid
anti SCl 70 antibody and probenecid
prostacyclin i2
anti SCl 70 antibody and prostacyclin i2
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The following are types of physicians relevant for 'anti SCl 70 antibody'.
related types of physicians 'family practitioner, internist, rheumatologist'
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web search results for 'anti scl 70 antibody'?
Results
1 - 50
- anti SCl 70 antibody
Anti-scl-70.
RESULTS: Anti-Scl 70 antibodies are very useful in distinguishing systemic ... As of yet, the need for serial testing of anti-Scl-70 has not been established. ...
http://www.ncbi.nlm.nih.gov/pubmed/15804707
www.ncbi.nlm.nih.gov
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summary
Anti-Scl-70 antibodies detected by immunoblotting in progressive ...
Anti-Scl-70 antibodies detected by immunoblotting in ... of anticentromere and anti Scl-70 antibodies in an English connective tissue disease population. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1003937
www.pubmedcentral.nih.gov
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summary
ANA (antinuclear antibody) Test - What Is An ANA (antinuclear antibody ...
ANA is a lab test performed on blood. ... Anti-DNA antibodies cause this pattern. ... (SSA, SSB), Scl-70 antibodies, anti-centromere, anti-histone, and anti-RN. ...
http://arthritis.about.com/od/diagnostic/a/ana.htm
arthritis.about.com
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summary
Anti-nuclear antibody - Wikipedia, the free encyclopedia
Anti-nuclear antibodies (ANAs, also known as anti ... Anti-nRNP (nuclear ribonucleoproteins) Anti Scl-70 (topoisomerase I) Anti-Jo ... Anti-cytoplasm antibody ...
http://en.wikipedia.org/wiki/Anti-nuclear_antibody
en.wikipedia.org
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summary
Frequency and clinical significance of anticentromere and anti Scl-70 ...
... of anticentromere and anti Scl-70 antibodies in an English connective tissue disease population. ... Anti Scl-70 was detected in 20% of the patients with ...
http://www.ncbi.nlm.nih.gov/pubmed/6412349
www.ncbi.nlm.nih.gov
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summary
Scl-86, a marker antigen for diffuse scleroderma.
... 13 reference sera) were also tested for the presence of anti-Scl-70 antibodies. ... all anti-Scl-70 positive sera (n = 25) contained anti-Scl-86 antibody as well, ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=423661
www.pubmedcentral.nih.gov
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summary
Anti-Scl-70 antibodies in autoimmune hypothyroidism.
... Scl-70 antibodies, which are highly specific for systemic sclerosis, have not ... a higher index level of anti-Scl-70, yet a negative anti-Scl-70 antibody test. ...
http://www.ncbi.nlm.nih.gov/pubmed/18304414
www.ncbi.nlm.nih.gov
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summary
Development of the Antinuclear and Anticytoplasmic Antibody Consensus ...
... conjugated anti-human immunoglobulin, and Wo/80 for antibodies to double ... Scl-70 antibody was found in sample B and in a minority of IP or HA and EIA ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=95891
www.pubmedcentral.nih.gov
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summary
Autoantibodies in systemic sclerosis and fibrosing syndromes: clinical ...
... pulmonary hypertension) compared with anti-Scl-70 and antinucleolar antibodies. Anti-Scl-70 antibodies are associated with diffuse cutaneous involvement, ...
http://www.ncbi.nlm.nih.gov/pubmed/15577611?dopt=Abstract
www.ncbi.nlm.nih.gov
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summary
Scleroderma Symptoms, Causes, Treatment, Prognosis and Diagnosis on ...
Read about scleroderma (an autoimmune disease) symptoms, causes, diagnosis, ... Anti-Scl 70 antibody (antitopoisomerase I antibody) is most often seen in ...
http://www.medicinenet.com/scleroderma/page3.htm
www.medicinenet.com
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summary
eMedicine - Mixed Connective-Tissue Disease : Article by Robert W Hoffman
... level of anti?U1-RNP antibodies, and antibodies against U1-70 kd small nuclear ... antibodies, including anticentromere, anti?Scl-70 (topoisomerase), and anti?PM ...
http://www.emedicine.com/med/topic3417.htm
www.emedicine.com
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summary
Anti-topoisomerase antibodies - Wikipedia, the free encyclopedia
Anti Scl-70 is recognized as one of two major classes of ... of anticentromere and anti Scl-70 antibodies in an English connective tissue disease population" ...
http://en.wikipedia.org/wiki/Anti-topoisomerase_antibodies
en.wikipedia.org
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summary
Clinical evaluation of autoantibodies to a novel PM/Scl peptide antigen
Anti-PM/Scl antibodies represent a specific serological marker for a subset of ... scleroderma-related antibodies anti-topoisomerase I (Scl-70) and anti-centromere. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=11...
www.pubmedcentral.nih.gov
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summary
Clinical significance of elevated antinuclear antibody test in patients ...
... had anti Jo-1, anti Scl-70, anti Sm, anti nRNP/Sm, anti ssDNA, antihistones ... antibody. Nuclear Proteins. Ribonucleoproteins, Small Nuclear. Scl 70 ...
http://www.ncbi.nlm.nih.gov/pubmed/18299692
www.ncbi.nlm.nih.gov
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summary
Autoantibody - Wikipedia, the free encyclopedia
Antinuclear antibody (ANA) Anti-p62 antibodies in primary biliary cirrhosis ... Anti-Scl 70 antibody (in sclerosis and scleroderma) Anti-topoisomerase antibodies ...
http://en.wikipedia.org/wiki/Autoantibody
en.wikipedia.org
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summary
Clinical evaluation of autoantibodies to a novel PM/Scl peptide antigen.
Anti-PM/Scl antibodies represent a specific serological marker for a subset of ... anti-Scl-70 (topoisomerase I), anti-Jo-1 (histidyl tRNA synthetase) and anti ...
http://www.ncbi.nlm.nih.gov/pubmed/15899056
www.ncbi.nlm.nih.gov
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summary
Topoisomerase - Wikipedia, the free encyclopedia
Topoisomerase I is the antigen recognized by Anti Scl-70 antibodies in scleroderma. ... Function, and Mechanism Annual Review of Biochemistry 70: 369-413[1] ...
http://en.wikipedia.org/wiki/Topoisomerase
en.wikipedia.org
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summary
Guide To Scleroderma - Diagnosis Of Scleroderma
A diagnosis of scleroderma is based largely on your medical history and findings ... Antitopoisomerase-1 or Anti-Scl-70 antibodies appear in the blood of up to 40 ...
http://arthritis.about.com/od/sclero/a/hohscleroderma_3.htm
arthritis.about.com
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summary
Natural killer cells and gamma delta T cells in scleroderma ...
... in their disease or with anti-Scl-70 antibodies accounted for the reduction ... patients, especially those with anti-Scl-70 antibodies and a disease duration of ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1005516
www.pubmedcentral.nih.gov
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summary
Autoantibodies to Extractable Nuclear Antigens: Making Detection and ...
These anti-Scl-70 antibodies may recognize different epitopes with a lower ... Similarly, IB assays may not detect some anti-Scl-70 antibodies (2, 19) ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=119916
www.pubmedcentral.nih.gov
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summary
Handout on Health: Scleroderma
Handout from the National Institutes of Health. ... Antitopoisomerase-1 or Anti-Scl-70 antibodies appear in the blood of up to 30 ...
http://www.niams.nih.gov/Health_Info/Scleroderma/default.asp
www.niams.nih.gov
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summary
[A case of rheumatoid arthritis associated with progressive systemic ...
... factor, anti-Scl-70 antibody, anti-mitochondrial antibody (anti-MC, anti-MD and ... unidentified fraction) and anti-centromere antibody have been observed with ...
http://www.ncbi.nlm.nih.gov/pubmed/1440089
www.ncbi.nlm.nih.gov
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summary
High-Quality, Cost-Effective Strategy for Detection of Autoantibodies ...
... was used to detect anti-SS-B, anti-RNP, anti-Sm, anti-Jo-1, and anti-Scl-70. Antibody controls. ... antibodies to SS-A, SS-B, RNP, Sm, Jo-1, and Scl-70 ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=96085
www.pubmedcentral.nih.gov
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summary
eMedicine - Systemic Sclerosis : Article by Robert A Schwartz
Antibodies against topoisomerase I DNA (Scl 70) are detected in ... performance in systemic sclerosis: anti-centromere and anti-Scl-70 antibodies. Am J Med. ...
http://www.emedicine.com/derm/topic677.htm
www.emedicine.com
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summary
Associations of right ventricular myocardial function with skin and ...
... pattern in 8 patients, and anti-Scl-70 antibodies in 15 patients. ... 35 mmHg, pulmonary fibrosis, a high mRSS, and an anti-Scl-70 antibody pattern. ...
http://www.ncbi.nlm.nih.gov/pubmed/15633438
www.ncbi.nlm.nih.gov
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summary
Juvenile systemic sclerosis: a follow-up study of eight patients.
... antibodies (ANAs), anti-centromere antibodies (ACAs), and anti-Scl-70 ... of these patients ever carried anti-Scl-70 antibodies, and only 2 of 8 patients ...
http://www.ncbi.nlm.nih.gov/pubmed/16126963
www.ncbi.nlm.nih.gov
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summary
Precise quantitation of antinuclear antibodies on HEp-2 cells without ...
... of the antigen reactive with anti-Scl-70 antibodies and its application in an ... Quantitative immunoassay of anti-La antibodies using purified recombinant ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=170353
www.pubmedcentral.nih.gov
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summary
eMedicine - CREST Syndrome : Article by Kyle L Horner
CREST (calcinosis, Raynaud phenomenon, esophageal dysmotility, sclerodactyly, and ... Anti-Scl-70 (anti-topoisomerase I) antibody is associated with diffuse ...
http://www.emedicine.com/derm/topic88.htm
www.emedicine.com
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summary
Periorbital cutaneous neonatal lupus.
... anemia, but anti-SSB, anti-Smith, U1RNP, and anti-Scl-70 antibodies were all negative. ... Anti-SSA antibody was positive at >6 units (reference, <1 unit) ...
http://www.ncbi.nlm.nih.gov/pubmed/17483660
www.ncbi.nlm.nih.gov
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summary
Antibodies against a novel nucleolar and cytoplasmic antigen (p105-p42 ...
... treated with actinomycin D probed with anti-U3 anti-PM/Scl antibodies (more ... of the antigen reactive with anti-Scl-70 antibodies and its application in an ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1905101
www.pubmedcentral.nih.gov
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summary
Immunologic parameters in systemic sclerosis.
... SSc: autoantibodies (antinuclear antibodies (ANA), anti-Scl-70, anticentromere ... Scl 70 antigen, human. procollagen Type III-N-terminal peptide ...
http://www.ncbi.nlm.nih.gov/pubmed/8112935?dopt=Citation
www.ncbi.nlm.nih.gov
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summary
Association of Phosphorylated Serine/Arginine (SR) Splicing Factors ...
... fibrillarin, anti-Ku, and anti?Scl-70 (M. Kuwana, Keio University Medical School, ... B, lane 6) and anti?U1-70 kD monoclonal antibodies (A and B, lane 4, ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2212144
www.pubmedcentral.nih.gov
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summary
Analysis of human antitopoisomerase-I idiotypes.
... protein (Scl-70) as a unique target of human antinuclear antibodies in ... of the antigen reactive with anti-Scl-70 antibodies and its application in an ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=288272
www.pubmedcentral.nih.gov
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summary
Historical Reference Ranges - Bloods
21-Hydroxylase Antibody. Anti-Adrenal 21 hydroxylase. 5' ... Scl 70 Autoantibodies, Serum. Topoisomerase, Scleroderma. Scrub Typhus Antibody. Rickettsial Ab ...
http://cclnprod.cc.nih.gov/dlm/testguide.nsf/HRRBlood?OpenFo...
cclnprod.cc.nih.gov
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summary
CRISP - Computer Retrieval of Information on Scientific Projects ...
... enigma, the presence of anti-nuclear antibodies in scleroderma patients is ... 1 (Scl-70), nuclear ribonucleoproteins (nRNP), centromere, PM-Scl, and Ku. ...
http://crisp.cit.nih.gov/crisp/CRISP_LIB.getdoc?textkey=6898...
crisp.cit.nih.gov
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summary
[Anti PM-Scl antibodies. Study of prevalence and of meaning]
2006 Sep;27(9):665-70. Epub 2006 Jun 12. [Anti PM-Scl antibodies. ... to appreciate the prevalence of antibodies anti PM-Scl within the framework of ...
http://www.ncbi.nlm.nih.gov/pubmed/16797795
www.ncbi.nlm.nih.gov
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summary
Parvoviral infection of endothelial cells and stromal fibroblasts: a ...
... antibody--specifically, an antinucleolar, anticentromere, and/or anti-Scl 70 antibody. ... Treatment strategies include anti-viral therapy, including in ...
http://www.ncbi.nlm.nih.gov/pubmed/14675284
www.ncbi.nlm.nih.gov
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summary
Prognostic markers for systemic sclerosis.
... antibodies are associated with delayed pulmonary hypertension, anti ... (Scl 70) with interstitial lung disease, and anti-RNA polymerase III antibodies ...
http://www.ncbi.nlm.nih.gov/pubmed/16798048
www.ncbi.nlm.nih.gov
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summary
Detection of anti-topoisomerase I antibodies using a full length human ...
... anti-Scl-70 (topoisomerase I) antibody associated with central nervous system ... Scl 70 autoantibodies from scleroderma patients recognize a 95 kDa protein ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1534349
www.pubmedcentral.nih.gov
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summary
eMedicine - Undifferentiated Connective-Tissue Disease : Article by ...
Many connective-tissue diseases (CTDs) share common signs and ... anti-SSB antibody, Smith antibody, RNP, antitopoisomerase antibody, sclerosis (Scl)-70 ...
http://www.emedicine.com/med/topic2937.htm
www.emedicine.com
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summary
[A case of systemic sclerosis and Sjogren's syndrome with cardiac ...
A 75-year-old woman was admitted to our hospital because of abnormal lung shadow ... positive result of anti-Scl-70 and SS-A antibody, sicca, decreased tear ...
http://www.ncbi.nlm.nih.gov/pubmed/16883110
www.ncbi.nlm.nih.gov
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summary
Angiogenic and angiostatic factors in systemic sclerosis: increased ...
... 2 cells and anti-topoisomerase I (Scl-70) antibodies were determined by ... for anti-Scl-70 autoantibodies and positive for antinuclear antibodies (median, ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=153841
www.pubmedcentral.nih.gov
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summary
Autoimmune sera recognize a 100 kD nuclear protein antigen (sp-100).
... patterns of anti-centromere, anti-RNP, anti-nucleolar and anti-Scl-70 antibodies. ... Fluorescent Antibody Technique. Humans. Male. Middle Aged. Molecular Weight ...
http://www.ncbi.nlm.nih.gov/pubmed/3308206
www.ncbi.nlm.nih.gov
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summary
Serum Levels of Tissue Inhibitors of Metalloproteinase 2 in Patients ...
Anti-Scl-70 antibodies were identified by using ELISA. ... between TIMP-1, TIMP-2, or MMP-1 and anti-Scl-70 or anticentromere antibody. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1775032
www.pubmedcentral.nih.gov
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summary
Extractable nuclear antigens - Wikipedia, the free encyclopedia
... laboratories for detection are Ro, La, Sm, RNP, Scl-70 and Jo1, which ... On anti-nuclear antibody tests, they have a speckled pattern.[1] [edit] Terminology ...
http://en.wikipedia.org/wiki/Extractable_nuclear_antigens
en.wikipedia.org
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summary
Autoantibodies to C-reactive protein (CRP) and other acute-phase ...
Serum antibodies to DNA, Ro/SSA, La/SSB, Sm, histones, Scl-70, centromere and ... of anti-mCRP antibodies was low: only two of 20 in the anti-Scl-70 and one ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1905069
www.pubmedcentral.nih.gov
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summary
The clinical relevance of serum antinuclear antibodies in Japanese ...
Anti-DNA topoisomerase I antibody (anti-topo I; formerly termed anti-Scl-70)5 ... protein (Scl-70) as a unique target of human antinuclear antibodies in scleroderma. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2344460
www.pubmedcentral.nih.gov
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summary
[Successful treatment with cyclosporine in a case of progressive ...
A 55-year-old man was admitted to our hospital with dyspnea on effort and ... skin lesions, interstitial pneumonia and the positivity for anti-Scl-70 antibody. ...
http://www.ncbi.nlm.nih.gov/pubmed/12931677
www.ncbi.nlm.nih.gov
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summary
Evaluation of Multiplexed Fluorescent Microsphere Immunoassay for ...
... 13 samples that were positive for Scl-70 antibodies by ELISA but negative by the ... interaction of anti-DNA antibodies with the Scl-70 ELISA (unpublished data) ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=524771
www.pubmedcentral.nih.gov
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summary
Immunoglobulin G subclass distribution of autoantibodies in systemic ...
... but most often IgG4; the diffusely grainy staining associated with Scl-70 antibody was chiefly IgG1; and the speckled pattern associated with anti-RNP ...
http://www.ncbi.nlm.nih.gov/pubmed/3115201
www.ncbi.nlm.nih.gov
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summary
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