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what is 'topoisomerase ii level'? Definition for Topoisomerase II level Topoisomerase II level is a medical procedure used for such diagnoses as: pelvic tumors, malignancy. related diagnosis for 'topoisomerase ii level' 1 - 2 of 2 diagnosis pelvic tumors tumors in pelvis Topoisomerase II level and pelvic tumors malignancy cancer Topoisomerase II level and malignancy related procedure for 'topoisomerase ii level'/associated diagnoses 1 - 5 of 62 procedures Abdominal CAT Scan Topoisomerase II level and Abdominal CAT Scan Abdominal MRI MRI of abdominal contents Topoisomerase II level and Abdominal MRI BUN Topoisomerase II level and BUN CA 125 (cancer antigen 125) Topoisomerase II level and CA 125 (cancer antigen 125) CA 19-9 (cancer antigen 19-9) Topoisomerase II level and CA 19-9 (cancer antigen 19-9) CT Pelvis Topoisomerase II level and CT Pelvis Carcinoembryonic Antigen (CEA) Topoisomerase II level and Carcinoembryonic Antigen (CEA) Chemotherapy Use of chemical substances to treat disease Topoisomerase II level and Chemotherapy Complete Blood Count Topoisomerase II level and Complete Blood Count Complete metabolic panel Topoisomerase II level and Complete metabolic panel Endoscopic surgery Topoisomerase II level and Endoscopic surgery Endoscopy Topoisomerase II level and Endoscopy Fecal Occult Blood Tests Test for occult blood in stool Topoisomerase II level and Fecal Occult Blood Tests Laparoscopy Minimally invasive surgery Topoisomerase II level and Laparoscopy Laparoscopy with biopsy Topoisomerase II level and Laparoscopy with biopsy Magnetic Resonance Imaging (MRI) Pelvis Topoisomerase II level and Magnetic Resonance Imaging (MRI) Pelvis Magnetic Resonance Imaging (MRI) female pelvis Topoisomerase II level and Magnetic Resonance Imaging (MRI) female pelvis Papanicolaou smear Topoisomerase II level and Papanicolaou smear Radiation Therapy Use of ionizing radiation or xrays for medical imaging or to treat cancer Topoisomerase II level and Radiation Therapy Serum Creatinine Topoisomerase II level and Serum Creatinine for more please login, login is free (click to login) related medication for 'topoisomerase ii level'/associated diagnoses 1 - 5 of 62 drugs 5-fluorouracil (5-fu) Topoisomerase II level and 5-fluorouracil (5-fu) 6-mercaptopurine (6-mp) Topoisomerase II level and 6-mercaptopurine (6-mp) actinomycin-d Topoisomerase II level and actinomycin-d alemtuzumab Topoisomerase II level and alemtuzumab alkylating agents Topoisomerase II level and alkylating agents altretamine Topoisomerase II level and altretamine anastrozole Topoisomerase II level and anastrozole anti tumor antibiotics Topoisomerase II level and anti tumor antibiotics antimetabolites Topoisomerase II level and antimetabolites arsenic trioxide Topoisomerase II level and arsenic trioxide bevacizumab Topoisomerase II level and bevacizumab bexarotene Topoisomerase II level and bexarotene bicalutamide Topoisomerase II level and bicalutamide bleomycin Topoisomerase II level and bleomycin bortezomib Topoisomerase II level and bortezomib busulfan Topoisomerase II level and busulfan capecitabine Topoisomerase II level and capecitabine carmustine (bcnu) Topoisomerase II level and carmustine (bcnu) cetuximab Topoisomerase II level and cetuximab chlorambucil Topoisomerase II level and chlorambucil for more please login, login is free (click to login) The following are types of physicians relevant for 'Topoisomerase II level'. related types of physicians 'family practitioner, gastroenterologist, gynecologist, internist, oncologist' show local physicians postal code Find Local stars represent relevance to topic not rating more The results are computer generated suggestions to help you find a physician. MEDgle does not recommend any particular type of physician or claim to be complete or accurate in the providers and specialties suggested. web search results for 'topoisomerase ii level'? Results 1 - 50 - Topoisomerase II level SUMO-2/3 regulates topoisomerase II in mitosis SUMO-2/3 regulates topoisomerase II in mitosis. Yoshiaki Azuma, Alexei ... Next, we examined the level of conjugated topoisomerase II as a function of ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173648/?tool=pubmed   www.ncbi.nlm.nih.gov - summary PIASy mediates SUMO-2 conjugation of Topoisomerase-II on ... PIASy mediates SUMO-2 conjugation of Topoisomerase-II on mitotic chromosomes ... Comparable total levels of Topoisomerase-II were associated with chromosomes from the ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1150894   www.pubmedcentral.nih.gov - summary Topoisomerase II alpha mRNA and tumour cell proliferation in ... Topoisomerase II alpha mRNA and tumour cell proliferation in non ... RESULTS: Levels of topoisomerase II alpha mRNA correlated strongly with the Ki-67 labelling index and were ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC499706/   www.ncbi.nlm.nih.gov - summary Yeast recombination pathways triggered by topoisomerase II ... Topoisomerase II is a ubiquitous enzyme that removes knots and ... Thus, it appears that the level of topoisomerase II-generated DNA damage induced by drugs ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC169887/?tool=pubmed   www.ncbi.nlm.nih.gov - summary Immunohistochemical study of topoisomerase II-alpha ... Immunohistochemical study of topoisomerase II-alpha expression in primary ductal carcinoma of the breast. ... Higher levels of topoisomerase II-alpha expression were strongly ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?&artid=502388   www.pubmedcentral.nih.gov - summary Inhibition of Human Topoisomerase II in Vitro by Bioactive ... Inhibition of Human Topoisomerase II in Vitro by Bioactive Benzene Metabolites http://ehp.niehs.nih.gov/docs/1996/Suppl-6/frantz.html   ehp.niehs.nih.gov - summary Differential expression of the topoisomerase II alpha and ... Topoisomerase II is a key target for several anti-cancer drugs used ... Moreover, the ratio of mRNA levels for topoisomerase II alpha and beta showed a stronger ... http://www.ncbi.nlm.nih.gov/pubmed/8664122   www.ncbi.nlm.nih.gov - summary Developmental regulation of Drosophila DNA topoisomerase II Affinity-purified polyclonal antibodies were used to quantitate steady- state levels of DNA topoisomerase II (topo II) throughout Drosophila development. ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2288815   www.pubmedcentral.nih.gov - summary Mechanism of action of eukaryotic topoisomerase II and drugs ... These drugs act in an insidious fashion and kill cells by increasing levels of covalent topoisomerase II-cleaved DNA complexes that are normally ... http://www.ncbi.nlm.nih.gov/pubmed/9748545   www.ncbi.nlm.nih.gov - summary Expression of a mutant DNA topoisomerase II in CCRF-CEM human ... Expression of a mutant DNA topoisomerase II in CCRF-CEM human leukemic cells ... CEM have decreased levels of DNA topoisomerase II catalytic activity and decreased ... http://www.ncbi.nlm.nih.gov/pubmed/1652758   www.ncbi.nlm.nih.gov - summary Topoisomerase II beta expression level correlates with ... Topoisomerase II beta expression level correlates with doxorubicin-induced apoptosis in peripheral blood cells. ... Strikingly, topo II beta activity correlated statistically ... http://www.ncbi.nlm.nih.gov/pubmed/16957942   www.ncbi.nlm.nih.gov - summary Overproduction of topoisomerase II in an ataxia ... Overproduction of topoisomerase II in an ataxia telangiectasia fibroblast cell ... Nuclear topoisomerase II levels correlate with the sensitivity of ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC331807/   www.ncbi.nlm.nih.gov - summary Abundance of nuclear DNA topoisomerase II is correlated with ... Topoisomerase II (TOPII) is an important enzyme involved in DNA replication and chromosome condensation. The level of TOPII expression has been ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC310140/   www.ncbi.nlm.nih.gov - summary Topoisomerase II? and IIß expression in childhood acute ... Topoisomerase II? and IIß expression in childhood acute lymphoblastic leukaemia: ... Nuclear topoisomerase II levels correlate with the sensitivity of ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1731267/?tool=pmcentrez   www.ncbi.nlm.nih.gov - summary Simultaneous quantitation of topoisomerase II alpha and beta ... Simultaneous quantitation of topoisomerase II alpha and beta isoform ... Topo II alpha and beta mRNA levels were both significantly lower in the squamous cell ... http://www.ncbi.nlm.nih.gov/pubmed/10879730   www.ncbi.nlm.nih.gov - summary XK469, a selective topoisomerase II? poison Topoisomerase II is an essential enzyme that alters DNA topology by carrying out an ATP ... II? levels drop sharply whereas topoisomerase II? levels remain ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC18430/   www.ncbi.nlm.nih.gov - summary Casein kinase II phosphorylates the eukaryote-specific ... Here we show that topoisomerase II is a phosphoprotein in yeast and that the level of incorporated phosphate is significantly higher at mitosis than in G1. ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?&artid=556636   www.pubmedcentral.nih.gov - summary Sensitivity of human type II topoisomerases to DNA damage ... These drugs act by increasing levels of topoisomerase II-mediated DNA cleavage. ... Levels of topoisomerase II? increase dramatically during periods of ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC103304/   www.ncbi.nlm.nih.gov - summary Topoisomerase I and II cleavage of adenovirus DNA in vivo ... Topoisomerase I and II cleavage of adenovirus DNA in vivo: both ... Sites of topoisomerase I and II cleavage across large portions of the adenovirus type 5 ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC249049/   www.ncbi.nlm.nih.gov - summary Doxorubicin-DNA adducts induce a non-topoisomerase II ... Doxorubicin-DNA adducts induce a non-topoisomerase II-mediated form of cell death. ... A reduction in the level of topoisomerase II-mediated double-strand-breaks was also ... http://www.nextbio.com/b/search/article.nb?id=16651442   www.nextbio.com - summary Inhibitors of DNA topoisomerase II prevent chromatid ... DNA topoisomerase II (EC 5.99.1.3) is necessary for chromosome condensation and ... with variable levels of endogenous topoisomerase II. J Cell Biol. ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC52617/   www.ncbi.nlm.nih.gov - summary c-erbB2 and topoisomerase II? protein expression ... c-erbB2 and topoisomerase II? protein expression independently ... one of many mechanisms causing high intracellular levels of the topoisomerase II? protein. ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1143560/?tool=pubmed   www.ncbi.nlm.nih.gov - summary Topoisomerase II cleavage of herpes simplex virus type 1 DNA ... Topoisomerase II sites were identified by means of the consensus ... Growth-related elevations of DNA topoisomerase II levels found in Dunning R3327 rat ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC247867/   www.ncbi.nlm.nih.gov - summary C-Terminal regions of topoisomerase II? and II? determine ... C-Terminal regions of topoisomerase II? and II? determine isoform ... Support of cell proliferation by topoisomerase II? requires highly elevated enzyme levels ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1920234/?tool=pubmed   www.ncbi.nlm.nih.gov - summary Mitotic chromatin condensation in vitro using somatic cell ... Mitotic chromatin condensation in vitro using somatic cell extracts and nuclei with variable levels of endogenous topoisomerase II ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2116389   www.pubmedcentral.nih.gov - summary Topoisomerase II DNA cleavage stimulation, DNA binding ... Topoisomerase II DNA cleavage stimulation, DNA binding activity, ... of the ability to stimulate topoisomerase II-mediated DNA damage in intact cells and with ... http://www.ncbi.nlm.nih.gov/pubmed/7623772   www.ncbi.nlm.nih.gov - summary Differential increase in topoisomerase II in simian virus 40 ... Differential increase in topoisomerase II in simian virus 40-infected cells. ... In contrast, the level of topoisomerase II increased markedly in SV40-infected cells but ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC249190/   www.ncbi.nlm.nih.gov - summary Doxorubicin-DNA adducts induce a non-topoisomerase II ... Doxorubicin is classified as a topoisomerase II poison, although other mechanisms of ... A reduction in the level of topoisomerase II-mediated double-strand-breaks was also ... http://www.ncbi.nlm.nih.gov/pubmed/16651442   www.ncbi.nlm.nih.gov - summary Human Topoisomerase II?: Targeting to Subchromosomal Sites of ... Mammalian topoisomerase II? (topo II?) plays a vital role in the ... In cycling cells topo II? levels rise steadily throughout S phase, reaching a peak during ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC404031/?tool=pmcentrez   www.ncbi.nlm.nih.gov - summary Interactions of Drosophila DNA topoisomerase II with left ... Topoisomerase II bound and relaxed mini-CG more readily than mini. ... cell extracts and nuclei with variable levels of endogenous topoisomerase II. J Cell Biol. ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC332542/   www.ncbi.nlm.nih.gov - summary Elevated DNA topoisomerase II activity in nitrogen mustard ... Elevated DNA topoisomerase II activity in nitrogen mustard-resistant human cells. ... In situ localization of DNA topoisomerase II, a major polypeptide component of ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC299361/   www.ncbi.nlm.nih.gov - summary Mutant isolation of mouse DNA topoisomerase II alpha in yeast. Mutant isolation of mouse DNA topoisomerase II alpha in yeast. ... In situ localization of DNA topoisomerase II, a major polypeptide component of the ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC331930/   www.ncbi.nlm.nih.gov - summary Expression of a mutant DNA topoisomerase II in CCRF-CEM human ... Expression of a mutant DNA topoisomerase II in CCRF-CEM human leukemic cells ... cell line CCRF-CEM have decreased levels of DNA topoisomerase II catalytic activity and ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC52360/   www.ncbi.nlm.nih.gov - summary DNA topoisomerase II alpha is the major chromosome protein ... DNA topoisomerase II alpha is the major chromosome protein recognized by the mitotic ... with variable levels of endogenous topoisomerase II. J Cell Biol. ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC47365/   www.ncbi.nlm.nih.gov - summary ABILITY OF VIRAL TOPOISOMERASE II TO DISCERN THE HANDEDNESS ... ABILITY OF VIRAL TOPOISOMERASE II TO DISCERN THE HANDEDNESS OF SUPERCOILED DNA: BIMODAL ... Both topoisomerase II? and ? maintain lower levels (2? to 4?fold) of ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2517260/?tool=pmcentrez   www.ncbi.nlm.nih.gov - summary Expression of topoisomerase IIalpha is associated with rapid ... DNA topoisomerase II alpha is the major chromosome protein recognized by the mitotic ... Relationship between topoisomerase II level and chemosensitivity in ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1861630/   www.ncbi.nlm.nih.gov - summary Topoisomerase II-mediated site-directed alkylation of DNA by ... Topoisomerase II-mediated site-directed alkylation of DNA by psorospermin and its use in ... the topoisomerase II cleaved complex and produces higher levels of ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC24853/   www.ncbi.nlm.nih.gov - summary Influence of Cell Cycle and Oncogene Activity upon ... The cell cycle, oncogenic signaling, and topoisomerase (topo) II? levels all influence sensitivity to anti-topo II drugs. Because the cell cycle ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC102171/   www.ncbi.nlm.nih.gov - summary Hypersensitivity of Ku-Deficient Cells toward the DNA ... For analysis of DNA topoisomerase II? levels, whole-cell extracts were obtained ... For analysis of DNA topoisomerase II? levels, cells were trypsinized, sedimented, ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC109166/   www.ncbi.nlm.nih.gov - summary Mms22p protects Saccharomyces cerevisiae from DNA damage ... The cleavage reaction of topoisomerase II, which creates double-stranded DNA breaks, ... Although drugs that increase levels of topoisomerase II-mediated DNA cleavage are front ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC549411/?tool=pmcentrez   www.ncbi.nlm.nih.gov - summary Amsacrine and etoposide hypersensitivity of yeast cells ... ... hypersensitivity of yeast cells overexpressing DNA topoisomerase II. Nitiss JL, Liu YX, Harbury P, ... a higher intracellular DNA topoisomerase II level is observed in both ... http://www.ncbi.nlm.nih.gov/pubmed/1322791   www.ncbi.nlm.nih.gov - summary Isolation of cDNA clones encoding the beta isozyme of human ... The proposed coding region for the topoisomerase II beta protein is 4,863 nucleotides ... We have quantified the level of topoisomerase II beta mRNA in a panel ... http://www.ncbi.nlm.nih.gov/pubmed/1333583   www.ncbi.nlm.nih.gov - summary Cloning and characterization of the 5'-flanking sequence for ... The levels of topoisomerase II isozymes are important determinants for the sensitivity of cells to the ... II. To investigate whether the expression of topoisomerase II ... http://www.ncbi.nlm.nih.gov/pubmed/9426241   www.ncbi.nlm.nih.gov - summary Proteasomal inhibition stabilizes topoisomerase II? protein ... Topoisomerase II is an ATP-dependent enzyme that catalyzes changes in DNA topology by ... Topo II? protein expression levels were analyzed using western blot ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2271051   www.pubmedcentral.nih.gov - summary Human cells express two differentially spliced forms of ... One form (designated topoisomerase II beta-1), representing the majority of the ... Topoisomerase II beta-2 mRNA was expressed at a lower level than that of the ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC309874/   www.ncbi.nlm.nih.gov - summary Method for quantifying expression of functionally active ... Method for quantifying expression of functionally active topoisomerase II in patients with leukaemia. ... Nuclear topoisomerase II levels correlate with the sensitivity of ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC500783/   www.ncbi.nlm.nih.gov - summary Human cells express two differentially spliced forms of ... The topoisomerase II beta-1 and beta-2 mRNAs were both widely expressed in human ... Topoisomerase II beta-2 mRNA was expressed at a lower level than that of the ... http://www.ncbi.nlm.nih.gov/pubmed/8396237   www.ncbi.nlm.nih.gov - summary Topoisomerase II-mediated alterations of K562 drug resistant ... Topoisomerase II-mediated alterations of K562 drug resistant sublines. ... Topo II-DNA complex formation induced by all studied drugs correlated with topo IIbeta ... http://www.ncbi.nlm.nih.gov/pubmed/10523799   www.ncbi.nlm.nih.gov - summary Molecular basis of the targeting of topoisomerase II-mediated ... Human topoisomerase II (topo II) is the cellular target for a number of widely used ... Topo II? levels increase during cell proliferation and this enzyme ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1447649/?tool=pmcentrez   www.ncbi.nlm.nih.gov - summary Depletion of topoisomerase II in isolated nuclei during a ... Depletion of topoisomerase II in isolated nuclei during a glucose ... Growth-related elevations of DNA topoisomerase II levels found in Dunning R3327 rat ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC362372/   www.ncbi.nlm.nih.gov - summary show more 1  2

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