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what is 'breakpoint cluster region (bcr)'? Definition for Breakpoint Cluster Region (BCR) Breakpoint Cluster Region (BCR) is a medical procedure used for such diagnoses as: chronic myeloid leukemia. related diagnosis for 'breakpoint cluster region (bcr)' 1 - 1 of 1 diagnosis chronic myeloid leukemia cancer of white blood cells Breakpoint Cluster Region (BCR) and chronic myeloid leukemia related procedure for 'breakpoint cluster region (bcr)'/associated diagnoses 1 - 5 of 43 procedures Abdominal CAT Scan Breakpoint Cluster Region (BCR) and Abdominal CAT Scan Abdominal MRI MRI of abdominal contents Breakpoint Cluster Region (BCR) and Abdominal MRI Abdominal ultrasonography Ultrasound of abdominal contents Breakpoint Cluster Region (BCR) and Abdominal ultrasonography Activated partial thromboplastin time Breakpoint Cluster Region (BCR) and Activated partial thromboplastin time BUN Breakpoint Cluster Region (BCR) and BUN Banded chromosome analysis Breakpoint Cluster Region (BCR) and Banded chromosome analysis Biopsy bone marrow Breakpoint Cluster Region (BCR) and Biopsy bone marrow Blood, Platelet Count Platelet Count Breakpoint Cluster Region (BCR) and Blood, Platelet Count Bone Marrow Aspiration Breakpoint Cluster Region (BCR) and Bone Marrow Aspiration Bone Marrow Transplant Breakpoint Cluster Region (BCR) and Bone Marrow Transplant Chemotherapy Use of chemical substances to treat disease Breakpoint Cluster Region (BCR) and Chemotherapy Chest X-ray Radiological technique to image the chest Breakpoint Cluster Region (BCR) and Chest X-ray Chromosomal analysis Breakpoint Cluster Region (BCR) and Chromosomal analysis Complete Blood Count Breakpoint Cluster Region (BCR) and Complete Blood Count Complete metabolic panel Breakpoint Cluster Region (BCR) and Complete metabolic panel Cytochemical evaluation Breakpoint Cluster Region (BCR) and Cytochemical evaluation Fluorescent in situ hybridization (FISH) Breakpoint Cluster Region (BCR) and Fluorescent in situ hybridization (FISH) Hematopoietic stem cell transplantation Breakpoint Cluster Region (BCR) and Hematopoietic stem cell transplantation Histocompatibility testing Breakpoint Cluster Region (BCR) and Histocompatibility testing Immunotherapy Breakpoint Cluster Region (BCR) and Immunotherapy for more please login, login is free (click to login) related medication for 'breakpoint cluster region (bcr)'/associated diagnoses 1 - 5 of 43 drugs arsenic trioxide(trisenox ) Breakpoint Cluster Region (BCR) and arsenic trioxide(trisenox ) busulfan Breakpoint Cluster Region (BCR) and busulfan busulfan(myleran , busulfex) Breakpoint Cluster Region (BCR) and busulfan(myleran , busulfex) cyclophosphamide Breakpoint Cluster Region (BCR) and cyclophosphamide cytarabine (ara-c) Breakpoint Cluster Region (BCR) and cytarabine (ara-c) cytarabine(cytosar-u , tarabine pfs) Breakpoint Cluster Region (BCR) and cytarabine(cytosar-u , tarabine pfs) dasatinib Breakpoint Cluster Region (BCR) and dasatinib dasatinib(sprycel ) Breakpoint Cluster Region (BCR) and dasatinib(sprycel ) hydroxyurea Breakpoint Cluster Region (BCR) and hydroxyurea hydroxyurea(hydrea) Breakpoint Cluster Region (BCR) and hydroxyurea(hydrea) imatinib Breakpoint Cluster Region (BCR) and imatinib imatinib(gleevec ) Breakpoint Cluster Region (BCR) and imatinib(gleevec ) interferon alfa-2a(roferon-a ) Breakpoint Cluster Region (BCR) and interferon alfa-2a(roferon-a ) interferon alfa-2b(intron a ) Breakpoint Cluster Region (BCR) and interferon alfa-2b(intron a ) interferon-alpha Breakpoint Cluster Region (BCR) and interferon-alpha nilotinib Breakpoint Cluster Region (BCR) and nilotinib nilotinib(tasigna ) Breakpoint Cluster Region (BCR) and nilotinib(tasigna ) vincristine. Breakpoint Cluster Region (BCR) and vincristine. for more please login, login is free (click to login) The following are types of physicians relevant for 'Breakpoint Cluster Region (BCR)'. related types of physicians 'family practitioner, hematologist, internist, oncologist' show local physicians postal code Find Local stars represent relevance to topic not rating more The results are computer generated suggestions to help you find a physician. MEDgle does not recommend any particular type of physician or claim to be complete or accurate in the providers and specialties suggested. web search results for 'breakpoint cluster region (bcr)'? Results 1 - 50 - Breakpoint Cluster Region (BCR) Breakpoint cluster region (BCR) Links. Breakpoint cluster region (BCR) SELECTED PROTEIN SIMILARITIES ... Homo sapiens breakpoint cluster region (BCR), transcript variant 1, mRNA. P. BC063619.1 ... http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=517461   www.ncbi.nlm.nih.gov - summary Breakpoint cluster region (BCR) Chicken protein-coding gene BCR. Represented by 8 ESTs from 8 cDNA libraries. ... Links. Breakpoint cluster region (BCR) SELECTED PROTEIN SIMILARITIES ... http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Gga&CID=28653   www.ncbi.nlm.nih.gov - summary Breakpoint cluster region (BCR) Human protein-coding gene BCR. Represented by 2 ESTs from 2 cDNA libraries. ... Links. Breakpoint cluster region (BCR) SELECTED PROTEIN SIMILARITIES ... http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=715409   www.ncbi.nlm.nih.gov - summary Breakpoint cluster region (Bcr) Norway rat protein-coding gene Bcr. Represented by 36 ESTs from 25 cDNA libraries. ... Links. Breakpoint cluster region (Bcr) SELECTED PROTEIN SIMILARITIES ... http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Rn&CID=12782   www.ncbi.nlm.nih.gov - summary Fine mapping of chromosome 22 breakpoints within the breakpoint cluster ... ... confined to a 5.8-kb segment referred to as the breakpoint cluster region (bcr) ... within the breakpoint cluster region (bcr) of chromosome 22 in chronic ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1683428   www.pubmedcentral.nih.gov - summary The first BCR gene intron contains breakpoints in Philadelphia ... ... breakpoint on chromosome 22 is located within the BCR gene: in CML, breakpoints are clustered within 5.8 kb of DNA, the major breakpoint cluster region (Mbcr) ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=338837   www.pubmedcentral.nih.gov - summary Genomic DNA breakpoints in AML1/RUNX1 and ETO cluster with ... ... kb breakpoint cluster region (BCR) (named BCR-1) at the 5? end of the 18.7-kb BamHI fragment. ... breakpoint cluster region. Top. Abstract. Materials and ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=122474   www.pubmedcentral.nih.gov - summary BCR gene - Wikipedia, the free encyclopedia Breakpoint cluster region. PDB rendering based on 1k1f. Available structures: 1k1f ... human [edit] References ^ "Entrez Gene: BCR breakpoint cluster region" ... http://en.wikipedia.org/wiki/BCR_gene   en.wikipedia.org - summary Duplication of small segments within the major breakpoint cluster ... ... within the major breakpoint cluster region in chronic myelogenous leukemia. ... deletion of a portion of the major breakpoint cluster region (M-bcr) of the BCR. ... http://www.ncbi.nlm.nih.gov/pubmed/8453102   www.ncbi.nlm.nih.gov - summary DNA cleavage within the MLL breakpoint cluster region is a specific ... DNA cleavage within the MLL breakpoint cluster region is a specific event which ... MLL gene on chromosome 11q23 within a breakpoint cluster region (bcr) of 8.3 kb. ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=232260   www.pubmedcentral.nih.gov - summary Breakpoint cluster region pseudogene (LOC728468) Breakpoint cluster region pseudogene (LOC728468) ... active BCR-related isoform 2. M. musculus. 60.0. 100. NP_001093486.1. hypothetical protein LOC565190 ... http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=589946   www.ncbi.nlm.nih.gov - summary Breakpoint cluster region pseudogene (LOC644165) Breakpoint cluster region pseudogene (LOC644165) SELECTED ... breakpoint cluster region homolog. M. musculus. 81.8. 148. NP_001080209.1. active BCR-related ... http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=655234   www.ncbi.nlm.nih.gov - summary T-cell immunity to the joining region of p210BCR-ABL protein. ... to the specific breakpoint cluster region (bcr) of the BCR gene on chromosome 22. ... that the joining region of BCR-ABL protein is immunogenic ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=1346932   www.pubmedcentral.nih.gov - summary Philadelphia chromosome - Wikipedia, the free encyclopedia ... by juxtapositioning of a part of the BCR ("breakpoint cluster region") gene ... Although the BCR region also expresses serine/threonine kinases, the tyrosine ... http://en.wikipedia.org/wiki/Philadelphia_chromosome   en.wikipedia.org - summary The chronic myelocytic cell line K562 contains a breakpoint in bcr and ... ... can be demonstrated with a probe from the bcr (breakpoint cluster region) ... the 5' region of bcr, we have cloned an amplified Ph1 breakpoint fragment from K562. ... http://www.ncbi.nlm.nih.gov/pubmed/3023859   www.ncbi.nlm.nih.gov - summary Breakpoint cluster region pseudogene (LOC644079) Breakpoint cluster region pseudogene (LOC644079) SELECTED PROTEIN SIMILARITIES ... active BCR-related. X. laevis. 60.2. 88. GENE EXPRESSION ... http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=648253   www.ncbi.nlm.nih.gov - summary Chronic Myelogenous Leukemia ... 9 oncogene to an area of chromosome 22 termed the breakpoint cluster region ... have BCR/ABL gene rearrangement detectable by Southern blot analysis, however, ... http://www.webmd.com/cancer/tc/leukemia-chronic-myelogenous-...   www.webmd.com - summary SNPs Localized to Chromosome 22 Interval 0 Similar to breakpoint cluster region. CGAP-C-56612. SNPs ... BCR. Breakpoint cluster region. CGAP-C-2458685. CGAP-C-2458686. CGAP-C-2458687. CGAP-C-2458688 ... http://gai.nci.nih.gov/cgi-bin/ival.cgi?c=22&i=0   gai.nci.nih.gov - summary PCR detection of a Maell polymorphism in the human major breakpoint ... PCR detection of a Maell polymorphism in the human major breakpoint cluster region (BCR) ... chromosome region 22q11: order of BCR loci relative to chronic ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?&artid=328831   www.pubmedcentral.nih.gov - summary Single Monochrome Real-Time RT-PCR Assay for Identification ... ... Quantification, and Breakpoint Cluster Region Determination of t ... common BCR-ABL rearrangement defines the major breakpoint cluster region (MBCR ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1867499   www.pubmedcentral.nih.gov - summary Heterogeneity of genomic fusion of BCR and ABL in Philadelphia ... ... the abnormality in the breakpoint cluster region-unrearranged form, we have ... kilobases upstream of a breakpoint cluster region in an intron of the BCR gene. ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=280086   www.pubmedcentral.nih.gov - summary PREDICTED: Homo sapiens similar to breakpoint cluster region ... PREDICTED: Homo sapiens similar to breakpoint cluster region (LOC100133163), mRNA (LOC100133163) ... active BCR-related. X. laevis. 65.0. 205. GENE EXPRESSION ... http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&MAXEST=999999&CID=318898   www.ncbi.nlm.nih.gov - summary Mapping of four distinct BCR-related loci to chromosome region 22q11 ... ... from the 3' region of the BCR gene (breakpoint cluster region gene) detects four ... are clustered within a limited region, bcr, on chromosome 22. Cell. ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=299252   www.pubmedcentral.nih.gov - summary AceView: gene:BCR, a comprehensive annotation of human, mouse and worm ... Homo sapiens complex locus BCR, encoding breakpoint cluster region. ... It has been described as breakpoint cluster region, breakpoint cluster region ... http://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?db=human&term=BCR   www.ncbi.nlm.nih.gov - summary FISH mapping of Philadelphia negative BCR/ABL1 positive CML ... a distal breakpoint cluster was found within a 280 Kb region containing the ... centromeric to the breakpoint and it was used to identify 5' BCR region. ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2500019   www.pubmedcentral.nih.gov - summary 151410 http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=151410   www.ncbi.nlm.nih.gov - summary Gleevec and Chronic Myeloid Leukemia - Cancer Information (Cancers ... Information on many different cancers includes symptoms, cancer ... ( ABL is short for Abelson and remember that BCR is short for breakpoint cluster region. ... http://www.medicinenet.com/script/main/art.asp?articlekey=17254&page=2   www.medicinenet.com - summary Nonrandom distribution of interspersed repeat elements in the BCR and ... ... in the BCR and ABL1 genes and its relation to breakpoint cluster regions. ... breakpoint cluster region (m-Bcr) towards the 3' end of the first BCR intron. ... http://www.ncbi.nlm.nih.gov/pubmed/11550282?ordinalpos=2&ito...   www.ncbi.nlm.nih.gov - summary Genomic and functional map of the chromosome 14 t(12;14) breakpoint ... ... the identification of expressed sequences that are altered in these BCR regions. ... identification of a large breakpoint cluster region on chromosome 14 suggests ... http://www.ncbi.nlm.nih.gov/pubmed/9740667   www.ncbi.nlm.nih.gov - summary The partial tandem duplication of ALL1 (MLL) is consistently generated ... ... identified within the 11q23 breakpoint cluster region (bcr) (17), and in vitro ... bcr. breakpoint cluster region. Footnotes ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?&artid=19353   www.pubmedcentral.nih.gov - summary Chromosomal translocations involving the MLL gene: molecular mechanisms ... hematologic malignancy can be mapped to an 8.3 kb breakpoint cluster region (bcr) ... are localized to a 8.3 kb breakpoint cluster region (bcr) ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1635494   www.pubmedcentral.nih.gov - summary Leukemia, chronic myelogenous: Treatment - Health Professional ... ... positivity for BCR/ABL (breakpoint cluster region/Abelson) translocation when ... for the transforming function of the BCR/ABL (breakpoint cluster region/Abelson) ... http://health.yahoo.com/leukemia-treatment/leukemia-chronic-...   health.yahoo.com - summary Breakpoint cluster region (BCR) Dog protein-coding gene BCR. Represented by 1 ESTs from 1 cDNA libraries. ... Links. Breakpoint cluster region (BCR) SELECTED PROTEIN SIMILARITIES ... http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Cfa&CID=43773   www.ncbi.nlm.nih.gov - summary Molecular Monitoring of Chronic Myelogenous Leukemia Monitoring breakpoint cluster region-Abelson kinase (BCR-ABL) levels in patients ... the 5? segment of the breakpoint cluster region (BCR) gene on chromosome 22 ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1867593   www.pubmedcentral.nih.gov - summary NCBI CDD cd04387 ... domain of Bcr (breakpoint cluster region protein)-like proteins. ... Bcr (breakpoint cluster region) protein binds to PDZ-domains of scaffold protein ... http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=63856   www.ncbi.nlm.nih.gov - summary Synergistic interactions between imatinib mesylate and the novel ... ... in 2 clinically relevant breakpoint cluster region (Bcr)-Abl mutant cell lines, ... that breakpoint cluster region/Ableson protein tyrosine (Bcr-Abl) kinase, ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1895085   www.pubmedcentral.nih.gov - summary Active BCR-related gene (ABR) PREDICTED: active breakpoint cluster region-related protein. P. ... PREDICTED: similar to active breakpoint cluster region-related protein isoform a ... http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=159306   www.ncbi.nlm.nih.gov - summary Leukemogenesis induced by wild-type and STI571-resistant BCR/ABL is ... ... resistant to therapy with the breakpoint cluster region?Abelson murine ... generates the breakpoint cluster region?Abelson murine leukemia (BCR/ABL) fusion ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1895881   www.pubmedcentral.nih.gov - summary PMID 15494376 Bcr (breakpoint cluster region) protein binds to PDZ-domains of scaffold protein ... 5535-41 The breakpoint cluster region protein (Bcr) is a large soluble ... http://www.ncbi.nlm.nih.gov/pubmed/15494376   www.ncbi.nlm.nih.gov - summary Treatment for chronic myelogenous leukemia: the long road to imatinib ... chromosome 9 and the breakpoint cluster region (BCR) gene on chromosome 22. The ... oncogene homolog; BCR, breakpoint cluster region; c-ABL, cellular ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1934577   www.pubmedcentral.nih.gov - summary Therapy options in imatinib failures. ... by the presence of the constitutively active tyrosine kinase breakpoint cluster region/Abelson (Bcr-Abl), which activates numerous signal transduction pathways ... http://www.ncbi.nlm.nih.gov/pubmed/18448557   www.ncbi.nlm.nih.gov - summary Evidence that the phl gene encodes a 160,000-dalton phosphoprotein with ... ... from chromosome 9 to a region on chromosome 22 designated as the breakpoint cluster region (bcr) (A. de Klein, A. Guerts van Kessel, G. Grosveld, C. R. ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=365301   www.pubmedcentral.nih.gov - summary PMID:8288633 820-3 Human breakpoint cluster region (bcr) gene product is a member of a group ... segment (GTPase-activating protein region) of Bcr and other known GTPase ... http://www.ncbi.nlm.nih.gov/pubmed/8288633   www.ncbi.nlm.nih.gov - summary Breakpoints on chromosomes 9 and 22 in Philadelphia chromosome-positive ... ... this 18-kb region, indicating that there are no breakpoint "hot spots" in this area. ... that lies within the previously described breakpoint cluster region (bcr) ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=423842   www.pubmedcentral.nih.gov - summary The BCR gene recombines preferentially with Alu elements in complex BCR ... ... of breakpoints in BCR occur within a 5 kb major breakpoint cluster region, M-Bcr. ... sequences mapped close to the breakpoint sites on other chromosomes in three ... http://www.ncbi.nlm.nih.gov/pubmed/9536079?ordinalpos=4&itoo...   www.ncbi.nlm.nih.gov - summary Human brain n-chimaerin cDNA encodes a novel phorbol ester receptor. ... BCR protein [product of the breakpoint-cluster-region (BCR) ... of protein kinase C and BCR, the product of the breakpoint cluster region gene. J Mol Biol. ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1150209   www.pubmedcentral.nih.gov - summary Poly(ADP-RIBOSE) polymerase-1 (Parp-1) antagonizes topoisomerase ... ... the RAR? breakpoint cluster region (bcr) comprising topoisomerase I recognition sites. ... breakpoint cluster region (bcr), which comprises two perfect ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1363779   www.pubmedcentral.nih.gov - summary BCR and its mutants, the reciprocal t(9;22)-associated ABL/BCR fusion ... ... translocation fuses the bcr (breakpoint cluster region) gene on chromosome 22 ... the bcr (breakpoint cluster region) locus and there are two principal regions in ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1637115   www.pubmedcentral.nih.gov - summary Active BCR-related gene (ABR) PREDICTED: similar to active breakpoint cluster region-related protein isoform a ... PREDICTED: active breakpoint cluster region-related protein. P. ... http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Bt&CID=43954   www.ncbi.nlm.nih.gov - summary PD166326, a novel tyrosine kinase inhibitor, has greater antileukemic ... ... myeloid leukemia (CML), but BCR/ABL (breakpoint cluster region/abelson murine ... free survival and in reducing BCR/ABL (breakpoint cluster region/abelson murine ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1895078   www.pubmedcentral.nih.gov - summary show more 1  2

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