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anti-scl-70 (anti-topoisomerase i) antibody
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what is 'anti-scl-70 (anti-topoisomerase i) antibody'?
Definition for Anti-Scl-70 (anti-topoisomerase I) antibody
antibody seen in certain collagen vascular diseases
Anti-Scl-70 (anti-topoisomerase I) antibody is also known as: anti SCl 70 antibody, anti topoisomerase 1 antibody, anti topoisomerase antibody
Anti-Scl-70 (anti-topoisomerase I) antibody is a medical procedure used for such diagnoses as: systemic lupus erythematosis, Sjogren's Syndrome and scleroderma.
related diagnosis for 'anti-scl-70 (anti-topoisomerase i) antibody'
1 - 4 of
4
diagnosis
systemic lupus erythematosis
multisystem connective tissue autoimmune disease
Anti-Scl-70 (anti-topoisomerase I) antibody and systemic lupus erythematosis
Sjogren's Syndrome
multisystem auto immune disease that also affects tear and salivary glands
Anti-Scl-70 (anti-topoisomerase I) antibody and Sjogren's Syndrome
scleroderma
multisystem disease with increased collagen deposits
Anti-Scl-70 (anti-topoisomerase I) antibody and scleroderma
CREST Syndrome
variant of scleroderma with limited manifestations
Anti-Scl-70 (anti-topoisomerase I) antibody and CREST Syndrome
related procedure for 'anti-scl-70 (anti-topoisomerase i) antibody'/associated diagnoses
1 - 5 of
107
procedures
Complete Blood Count
Anti-Scl-70 (anti-topoisomerase I) antibody and Complete Blood Count
Anti-single stranded DNA antibodies (anti-ssDNA)
Anti-Scl-70 (anti-topoisomerase I) antibody and Anti-single stranded DNA antibodies (anti-ssDNA)
BUN
Anti-Scl-70 (anti-topoisomerase I) antibody and BUN
Erythrocyte Sedimentation Rate (ESR)
Anti-Scl-70 (anti-topoisomerase I) antibody and Erythrocyte Sedimentation Rate (ESR)
Serum Creatinine
Anti-Scl-70 (anti-topoisomerase I) antibody and Serum Creatinine
Single-Stranded (ss)-DNA Antibody
Anti-Scl-70 (anti-topoisomerase I) antibody and Single-Stranded (ss)-DNA Antibody
indirect immunofluorescence (IIF)
Anti-Scl-70 (anti-topoisomerase I) antibody and indirect immunofluorescence (IIF)
CT scan
Anti-Scl-70 (anti-topoisomerase I) antibody and CT scan
Anti La (SSB) antibody
Anti-Scl-70 (anti-topoisomerase I) antibody and Anti La (SSB) antibody
Anti-Ro (SS-A) antibodies
antibodies against certain collagen vascular diseases
Anti-Scl-70 (anti-topoisomerase I) antibody and Anti-Ro (SS-A) antibodies
Antihistone antibodies
Anti-Scl-70 (anti-topoisomerase I) antibody and Antihistone antibodies
Antiphospholipid antibodies
anribodies seen in inappropriate clot formation
Anti-Scl-70 (anti-topoisomerase I) antibody and Antiphospholipid antibodies
Biopsy
Anti-Scl-70 (anti-topoisomerase I) antibody and Biopsy
Biopsy skin
Anti-Scl-70 (anti-topoisomerase I) antibody and Biopsy skin
Blood, Platelet Count
Platelet Count
Anti-Scl-70 (anti-topoisomerase I) antibody and Blood, Platelet Count
Complete metabolic panel
Anti-Scl-70 (anti-topoisomerase I) antibody and Complete metabolic panel
ECHOcardiogram
Anti-Scl-70 (anti-topoisomerase I) antibody and ECHOcardiogram
Extractable nuclear antigen (ENA)
Anti-Scl-70 (anti-topoisomerase I) antibody and Extractable nuclear antigen (ENA)
Immune Complex Test
Anti-Scl-70 (anti-topoisomerase I) antibody and Immune Complex Test
Liver Function Tests
elevated liver enzymes
Anti-Scl-70 (anti-topoisomerase I) antibody and Liver Function Tests
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related medication for 'anti-scl-70 (anti-topoisomerase i) antibody'/associated diagnoses
1 - 5 of
107
drugs
cyclophosphamide
Anti-Scl-70 (anti-topoisomerase I) antibody and cyclophosphamide
azathioprine
Anti-Scl-70 (anti-topoisomerase I) antibody and azathioprine
azathioprine(imuran)
Anti-Scl-70 (anti-topoisomerase I) antibody and azathioprine(imuran)
cyclophosphamide(cytoxan)
Anti-Scl-70 (anti-topoisomerase I) antibody and cyclophosphamide(cytoxan)
hydroxychloroquine
Anti-Scl-70 (anti-topoisomerase I) antibody and hydroxychloroquine
methotrexate
Anti-Scl-70 (anti-topoisomerase I) antibody and methotrexate
methotrexate(trexall)
Anti-Scl-70 (anti-topoisomerase I) antibody and methotrexate(trexall)
prednisone
Anti-Scl-70 (anti-topoisomerase I) antibody and prednisone
prednisone(deltasone)
Anti-Scl-70 (anti-topoisomerase I) antibody and prednisone(deltasone)
diclofenac(voltaren)
Anti-Scl-70 (anti-topoisomerase I) antibody and diclofenac(voltaren)
hydrocortisone(cortef )
Anti-Scl-70 (anti-topoisomerase I) antibody and hydrocortisone(cortef )
hydroxychloroquine(plaquenil sulfate)
Anti-Scl-70 (anti-topoisomerase I) antibody and hydroxychloroquine(plaquenil sulfate)
ibuprofen(motrin)
Anti-Scl-70 (anti-topoisomerase I) antibody and ibuprofen(motrin)
indomethacin(indocin)
Anti-Scl-70 (anti-topoisomerase I) antibody and indomethacin(indocin)
methylprednisolone
Anti-Scl-70 (anti-topoisomerase I) antibody and methylprednisolone
naproxen(naprelan '500' )
Anti-Scl-70 (anti-topoisomerase I) antibody and naproxen(naprelan '500' )
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The following are types of physicians relevant for 'Anti-Scl-70 (anti-topoisomerase I) antibody'.
related types of physicians 'dermatologist, family practitioner, internist, nephrologist, neurologist, neurosurgeon, rheumatologist'
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web search results for 'anti-scl-70 (anti-topoisomerase i) antibody'?
Results
1 - 50
- Anti-Scl-70 (anti-topoisomerase I) antibody
Autoantibody - Wikipedia, the free encyclopedia
Antinuclear antibody (ANA) Anti-p62 antibodies in primary biliary cirrhosis ... Anti-Scl 70 antibody (in sclerosis and scleroderma) Anti-topoisomerase antibodies ...
http://en.wikipedia.org/wiki/Autoantibody
en.wikipedia.org
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summary
Anti-Scl-70 antibodies detected by immunoblotting in progressive ...
... titers of autoantibodies to topoisomerase I (Scl-70) in sera from scleroderma patients. ... Anti-centromere antibody and its relationship to CREST syndrome. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1003937
www.pubmedcentral.nih.gov
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Anti-topoisomerase antibodies - Wikipedia, the free encyclopedia
... of Anti Scl-70 was recognized as topoisomerase I in 1986[2] with anti-centromere ... with anti-topoisomerase I- and anticentromere antibody-positive ...
http://en.wikipedia.org/wiki/Anti_Scl-70
en.wikipedia.org
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summary
Anti-nuclear antibody - Wikipedia, the free encyclopedia
Anti-nRNP (nuclear ribonucleoproteins) Anti Scl-70 (topoisomerase I) Anti-centromere. Anti-Jo ... Anti-sp100 - Anti-thrombin - Anti-topoisomerase - Anti ...
http://en.wikipedia.org/wiki/Anti-nuclear_antibody
en.wikipedia.org
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summary
CRISP - Computer Retrieval of Information on Scientific Projects ...
... topoisomerase 1 (Scl-70), nuclear ribonucleoproteins (nRNP), centromere, PM-Scl, and Ku. ... of the anti-nRNP and anti-topoisomerase autoantibodies found ...
http://crisp.cit.nih.gov/crisp/CRISP_LIB.getdoc?textkey=6898...
crisp.cit.nih.gov
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summary
Antibodi anti-nuklear - Wikipedia Indonesia, ensiklopedia bebas ...
Anti-nRNP (ribonukleoprotein nukleus) Anti Scl-70 (topoisomerase I) Anti-centromere. Anti-Jo ... clinical use of the antinuclear antibody test and tests for specific ...
http://id.wikipedia.org/wiki/Antibodi_anti-nuklear
id.wikipedia.org
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summary
eMedicine - CREST Syndrome : Article by Kyle L Horner
... (1) autoantibodies to centromere proteins, Scl-70 (topo I) and fibrillarin; (2) ... Anti-Scl-70 (anti-topoisomerase I) antibody is associated with diffuse ...
http://www.emedicine.com/derm/topic88.htm
www.emedicine.com
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summary
Computer-Assisted Pattern Recognition of Autoantibody Results
Immunoassay-based anti-nuclear antibody (ANA) screens are increasingly used in ... Jo-1, ribosomal protein, Scl-70 (topoisomerase), centromere B, chromatin, and ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1317078
www.pubmedcentral.nih.gov
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eMedicine - Mixed Connective-Tissue Disease : Article by Robert W Hoffman
... with the presence of a distinctive antibody against what now is known to be ... including anticentromere, anti?Scl-70 (topoisomerase), and anti?PM-1 (Pm-Scl) ...
http://www.emedicine.com/med/topic3417.htm
www.emedicine.com
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The clinical relevance of autoantibodies in scleroderma
Anti-Scl-70 (anti-topoisomerase I) antibodies. ANoA. Other autoantibodies. Summary ... Unlike ACA, anti-Scl-70 antibody frequency has been shown not to vary depending ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?&artid=165038
www.pubmedcentral.nih.gov
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Historical Reference Ranges - All
Anti-Adrenal Antibody  . Catecholamines, Fractionated, 12 hr ... Scl 70 Autoantibodies, Serum. Topoisomerase, Scleroderma. Sex Hormone Binding Globulin ...
http://cclnprod.cc.nih.gov/dlm/testguide.nsf/HRRProtocols?OpenForm
cclnprod.cc.nih.gov
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summary
Clinical evaluation of autoantibodies to a novel PM/Scl peptide antigen
... characterized the antibody response to a major PM/Scl epitope and ... scleroderma-related antibodies anti-topoisomerase I (Scl-70) and anti-centromere. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=11...
www.pubmedcentral.nih.gov
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summary
ii.nlm.nih.gov/TestCollections/FullText/PubMedCentral.medline
PMID- 10984461 OWN - NLM STAT- MEDLINE DA - 20001016 DCOM- 20001016 LR ... PG - 512-6 FAU - Kohane, I S AU - Kohane IS LA - eng PT - Comment PT - Editorial ...
http://ii.nlm.nih.gov/TestCollections/FullText/PubMedCentral.medline
ii.nlm.nih.gov
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eMedicine - Systemic Sclerosis : Article by Robert A Schwartz
Antibodies against topoisomerase I DNA (Scl 70) in approximately 30% of patients ... C-reactive protein and anti-mitochondria antibody in patients with ...
http://www.emedicine.com/derm/topic677.htm
www.emedicine.com
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summary
Autoantibodies to Extractable Nuclear Antigens: Making Detection and ...
STRATEGIES FOR ANTI-ENA ANTIBODY TESTING. MEANINGFUL ENA TEST ... Anti-topoisomerase I (anti-Scl-70) antibodies in patients with systemic lupus erythematosus. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=119916
www.pubmedcentral.nih.gov
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Historical Reference Ranges - Bloods
... I  . Angiotensin II  . Anti-Adrenal Antibody   ... Scl 70 Autoantibodies, Serum. Topoisomerase, Scleroderma. Scrub Typhus Antibody. Rickettsial Ab ...
http://cclnprod.cc.nih.gov/dlm/testguide.nsf/HRRBlood?OpenFo...
cclnprod.cc.nih.gov
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Epidemiology of organic solvents and connective tissue disease
... for anti-Scl-70 antibody, suggesting that solvents may bind to topoisomerase I ... Anti-topoisomerase I antibodies in silica-associated systemic sclerosis. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=129987
www.pubmedcentral.nih.gov
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eMedicine - Calcinosis Cutis : Article by Julia R Nunley
... the presence of SCL-70 (topoisomerase) antibody portends a poor prognosis. ... be beneficial because of their anti-inflammatory and inhibitory effects on ...
http://www.emedicine.com/derm/topic66.htm
www.emedicine.com
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All Tests
Anti-Meningococcus IgG Antibody. MENG3. Neisseria Meningitids IgG ... Scl 70 Autoantibodies, Serum. SCL70. Topoisomerase, Scleroderma. Red/Yellow Rim 4mL SST ...
http://cclnprod.cc.nih.gov/dlm/testguide.nsf/ReferralTests?O...
cclnprod.cc.nih.gov
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summary
Serum TIMP-1, TIMP-2, and MMP-1 in patients with systemic sclerosis ...
... status (anti-topoisomerase 1 (anti-Scl-70), anticentromere antibody, or anti-RNA ... OF TRIPLE-HELICAL TYPE I AND TYPE III PROCOLLAGENS ASSOCIATED ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1753839
www.pubmedcentral.nih.gov
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summary
eMedicine - Multiple Sclerosis : Article by Fernando Dangond
... variable degrees of antibody-producing plasma cell ... for the following: anticardiolipin, anti-beta2 glycoprotein I, and antiprothrombin antibodies. ...
http://www.emedicine.com/neuro/topic228.htm
www.emedicine.com
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summary
Serum Levels of Tissue Inhibitors of Metalloproteinase 2 in Patients ...
... 2 levels and anti-Scl-70 (anti-topoisomerase 1) nor anticentromere antibodies. ... between TIMP-1, TIMP-2, or MMP-1 and anti-Scl-70 or anticentromere antibody. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1775032
www.pubmedcentral.nih.gov
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summary
Cytokine and chemokine levels in systemic sclerosis: relationship with ...
... SSc include anticentromere antibodies (ACA) and anti scl-70 (antitopoisomerase I) ... with lc-SSc, while anti-Topoisomerase I antibodies (scl70) were ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pub...
www.pubmedcentral.nih.gov
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summary
Correlation of Endostatin and Tissue Inhibitor of Metalloproteinases 2 ...
... following ANA were observed: anti-topoisomerase I (10 patients), U3RNP ... antinuclear antibodies were identified: anti-Scl 70 antibodies (10 patients, in ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pub...
www.pubmedcentral.nih.gov
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summary
All Tests
Anti-HTLV-I/II. HTLV. Antibody to HTLV virus types I and II. Hepatitis ... Scl 70 Autoantibodies, Serum. SCL70. Topoisomerase, Scleroderma. Mayo Medical Labs ...
http://cclnprod.cc.nih.gov/dlm/testguide.nsf/TestIndex?OpenForm&Count=5000/
cclnprod.cc.nih.gov
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summary
Anti-topoisomerase II ? autoantibodies in systemic sclerosis ...
... either anti-topoisomerase I (Scl-70 or anti-topo I) or anti-centromere antibodies. ... sclerosis and anti-DNA topoisomerase I antibody. Arthritis Rheum. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1905723
www.pubmedcentral.nih.gov
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Systemic sclerosis: an autoantibody mosaic
... (ACA) and DNA topoisomerase I (ATA), formerly called anti-Scl-70, are the most ... in patients with systemic sclerosis and anti-DNA topoisomerase antibody. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1905344
www.pubmedcentral.nih.gov
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summary
Chromosome studies in systemic sclerosis with consideration of ...
... titers of autoantibodies to topoisomerase I (Scl-70) in sera from scleroderma patients. ... J. Specificity of anti-Scl-70 antibodies in scleroderma: ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1005694
www.pubmedcentral.nih.gov
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summary
T cell proliferative response induced by DNA topoisomerase I in ...
... absence of SSc or anti-topo I antibody, but is restricted by ... titers of autoantibodies to topoisomerase I (Scl-70) in sera from scleroderma patients. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=185233
www.pubmedcentral.nih.gov
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FY03 RESEARCH INITIATIVES
... Treatment (STD) employing an intraoral splint plus anti ... i) control, ii) inflamed muscle, iii) inflamed muscle with intervention (anti-nerve growth ...
http://orwh.od.nih.gov/research/FY05_ResearchSummaries.pdf
orwh.od.nih.gov
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summary
Autoantibodies to C-reactive protein (CRP) and other acute-phase ...
... SSc and antibodies to topoisomerase I (Scl-70), 22 SSc patients with ... peroxidase (HRP)-conjugated goat anti-IgG antibody (Medac GmbH, Hamburg, Germany) ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1905069
www.pubmedcentral.nih.gov
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Association of polar amino acids at position 26 of the HLA-DQB1 first ...
Anti-centromere antibody and its relationship to CREST syndrome. ... titers of autoantibodies to topoisomerase I (Scl-70) in sera from scleroderma patients. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=442980
www.pubmedcentral.nih.gov
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Increased Levels of Alternatively Spliced Interleukin 4 (IL-4?2 ...
... of the anti-topoisomerase I autoantibodies (formerly Scl 70) (21) which are ... Third, administration of anti-IL-4 antibody prevents graft-versus-host disease ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=95750
www.pubmedcentral.nih.gov
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articles
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&db=...
www.ncbi.nlm.nih.gov
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www.niehs.nih.gov/research/atniehs/core/microarrays/docs/p84s65_si_fci.txt
... 0.1392 1 "nuclear receptor subfamily 1, group I, member 3" X56199 9E05 0 1 781 1 ... 99.0 0.5848 1.7101 0.8842 0.1392 1 topoisomerase-related function protein 4 ...
http://www.niehs.nih.gov/research/atniehs/core/microarrays/d...
www.niehs.nih.gov
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summary
Association of amino acid sequences in the HLA-DQB1 first domain with ...
Anti-centromere antibody and its relationship to CREST syndrome. ... titers of autoantibodies to topoisomerase I (Scl-70) in sera from scleroderma patients. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=1326003
www.pubmedcentral.nih.gov
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The HLA-DR and DQ genes control the autoimmune response to DNA ...
... DR52 demonstrated higher anti-topo I antibody titers. ... distribution of epitopes on topoisomerase I (Scl-70) recognized by sera of scleroderma patients. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=7690776
www.pubmedcentral.nih.gov
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Autoantibodies to RNA polymerase II are common in systemic lupus ...
... anti-Ku, anti-nRNP, or anti-topoisomerase I autoantibodies in ... titers of autoantibodies to topoisomerase I (Scl-70) in sera from scleroderma patients. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=7962544
www.pubmedcentral.nih.gov
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An acquired antithrombin autoantibody directed toward the catalytic ...
... titers of autoantibodies to topoisomerase I (Scl-70) in sera from scleroderma patients. ... Anti-neutrophil cytoplasmic autoantibodies with specificity for ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=296031
www.pubmedcentral.nih.gov
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Interactions between autoimmunity and molecular and cell biology ...
Scl 70 autoantibodies from scleroderma patients recognize a 95 kDa protein identified as DNA topoisomerase I. Chromosoma. 1986;94(2):132?138. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=303945
www.pubmedcentral.nih.gov
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The U2 small nuclear ribonucleoprotein particle as an autoantigen ...
... antibody and definition of their constituent proteins reacting ... titers of autoantibodies to topoisomerase I (Scl-70) in sera from scleroderma patients. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=442616
www.pubmedcentral.nih.gov
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Autoantibodies in cryptogenic fibrosing alveolitis
... include antinuclear antibodies, anti-DNA topoisomerase II antibodies and ... expression of autoantibodies (as with Scl-70 in systemic sclerosis) and clinical ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=59568
www.pubmedcentral.nih.gov
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Role for Homodimerization in Growth Deregulation by E2a Fusion Proteins
... in phosphate-buffered saline (PBS), lysed in 70 ?l of protein sample buffer, and ... peroxidase-conjugated, anti-mouse secondary antibody (Jackson ImmunoResearch ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=86056
www.pubmedcentral.nih.gov
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Caspase-mediated cleavage of the exosome subunit PM/Scl-75 during apoptosis
CCRF-CEM cells were also treated with the anti-Fas antibody. ... autoantigens such as DNA topoisomerase I and Sm-F have also been reported to be ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pub...
www.pubmedcentral.nih.gov
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Poly(ADP-RIBOSE) polymerase-1 (Parp-1) antagonizes topoisomerase ...
... presence of topoisomerase I was revealed by the human antiserum Scl-70 (1:5000; ... antibody DO1 (1:10000; Calbiochem, Bad Soden) and anti-mouse and anti-goat ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1363779
www.pubmedcentral.nih.gov
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Anti-fibrillarin autoantibodies in mercury-treated mice.
... 95 kDa protein identified as DNA topoisomerase I. Chromosoma. 1986;94(2):132 ... Scl 70 antibody--a specific marker of systemic sclerosis. Br J Dermatol. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1534831
www.pubmedcentral.nih.gov
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DNA Repair Protein Involved in Heart and Blood Development
... (New England Biolabs) and heated to 70°C to inactivate the kinase, the ... Secondary antibody (goat anti-rabbit immunoglobulin G-horseradish peroxidase ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1636828
www.pubmedcentral.nih.gov
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Analysis of anticentromere autoantibodies using cloned autoantigen CENP-B.
... titers of autoantibodies to topoisomerase I (Scl-70) in sera from scleroderma patients. ... lupus erythematosus marker antibody anti-Sm. J Clin Invest. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=305230
www.pubmedcentral.nih.gov
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Improved Serological Differentiation between Systemic Lupus ...
... recombinant antigen), Scl-70 (human recombinant topoisomerase 1), CENP (human ... sera from MCTD patients, common anti-Sm antibody assays with purified Sm or ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=540222
www.pubmedcentral.nih.gov
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Regulation of Transcription Factor YY1 by Acetylation and Deacetylation
... transfected into HeLa cells and immunoprecipitated with anti-Flag antibody. ... UBF (48), TAL1 (also known as SCL) (25), and nuclear receptor coactivators ACTR, ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pub...
www.pubmedcentral.nih.gov
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