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vincristine
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what is 'vincristine'?
Definition for vincristine - Vincasar
Vincristine (brand name, Oncovin), also known as leurocristine , is a vinca alkaloid from the Catharanthus roseus (Madagascar periwinkle), formerly Vinca rosea and hence its name. It is a mitotic inhibitor , and is used in cancer chemotherapy .
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Vincristine (brand name, Oncovin), also known as leurocristine , is a vinca alkaloid from the Catharanthus roseus (Madagascar periwinkle), formerly Vinca rosea and hence its name. It is a mitotic inhibitor , and is used in cancer chemotherapy .
Tubulin is a structural protein which polymerises to form microtubules . The cell cytoskeleton and mitotic spindle , amongst other things, are made of microtubules. Vincristine binds to tubulin dimers, inhibiting assembly of microtubule structures. Disruption of the microtubules arrests mitosis in metaphase . The vinca alkaloids therefore affect all rapidly dividing cell types including cancer cells, but also intestinal epithelium and bone marrow .
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diagnoses treated with 'vincristine'
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32
diagnosis
bronchogenic carcinoma
lung cancer
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vincristine and bronchogenic carcinoma
acute lymphocytic leukemia
cancer of white blood cells
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vincristine and acute lymphocytic leukemia
intracranial tumor
brain tumor
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vincristine and intracranial tumor
malignancy
cancer
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vincristine and malignancy
rhabdomyosarcoma
malignancy of muscles
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vincristine and rhabdomyosarcoma
Wilm's tumor
kidney tumor of childhood
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vincristine and Wilm's tumor
chronic lymphocytic leukemia
cancer of white blood cells
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vincristine and chronic lymphocytic leukemia
medulloblastoma
type of brain tumor
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vincristine and medulloblastoma
neuroblastoma
childhood malignant tumor developing from nerve tissue
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vincristine and neuroblastoma
retinoblastoma
cancer of retina
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vincristine and retinoblastoma
choriocarcinoma
cancer of certain cells of the placenta
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vincristine and choriocarcinoma
dysgerminoma
rare ovarian tumor
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vincristine and dysgerminoma
ependymoma
brain tumor arising from inner lining of brain ventricles
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vincristine and ependymoma
hepatocellular carcinoma
liver cancer
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vincristine and hepatocellular carcinoma
metastases
spread of malignant tumors to other body sites
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vincristine and metastases
oligodendroglioma
type of brain tumor
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vincristine and oligodendroglioma
Castleman's disease
non cancerous growths in lymph nodes
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vincristine and Castleman's disease
ganglioglioma
benign brain tumor
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vincristine and ganglioglioma
persistent gestational trophoblastic tumor
benign or malignant growth of trophoblastic tissue
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vincristine and persistent gestational trophoblastic tumor
polyembryoma
rare germ cell tumor of ovary
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vincristine and polyembryoma
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related procedures when taking 'vincristine'
1 - 5 of
153
procedures
CT scan
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vincristine and CT scan
Complete Blood Count
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vincristine and Complete Blood Count
Brain MRI
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vincristine and Brain MRI
Abdominal CAT Scan
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vincristine and Abdominal CAT Scan
Radiation Therapy
Use of ionizing radiation or xrays for medical imaging or to treat cancer
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vincristine and Radiation Therapy
Complete metabolic panel
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vincristine and Complete metabolic panel
serum electrolytes
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vincristine and serum electrolytes
CT chest
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vincristine and CT chest
CT brain
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vincristine and CT brain
Biopsy
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vincristine and Biopsy
Chest X-ray
Radiological technique to image the chest
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vincristine and Chest X-ray
Chemotherapy
Use of chemical substances to treat disease
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vincristine and Chemotherapy
Positron emission tomography (PET)
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vincristine and Positron emission tomography (PET)
Resection
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vincristine and Resection
Tumor markers
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vincristine and Tumor markers
Blood, Platelet Count
Platelet Count
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vincristine and Blood, Platelet Count
Lactate dehydrogenase (LDH)
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vincristine and Lactate dehydrogenase (LDH)
bone scan
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vincristine and bone scan
Lymph node biopsy
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vincristine and Lymph node biopsy
Cytodiagnosis
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vincristine and Cytodiagnosis
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related medication for 'vincristine'
1 - 5 of
105
drugs
etoposide
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vincristine and etoposide
cyclophosphamide
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vincristine and cyclophosphamide
cisplatin
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vincristine and cisplatin
doxorubicin
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vincristine and doxorubicin
carboplatin
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vincristine and carboplatin
ifosfamide
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vincristine and ifosfamide
gemcitabine
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vincristine and gemcitabine
methotrexate
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vincristine and methotrexate
temozolomide
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vincristine and temozolomide
chlorambucil
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vincristine and chlorambucil
prednisone
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vincristine and prednisone
bleomycin
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vincristine and bleomycin
cytarabine
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vincristine and cytarabine
cyclophosphamide(cytoxan)
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vincristine and cyclophosphamide(cytoxan)
thiotepa
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vincristine and thiotepa
topoisomerase inhibitors
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vincristine and topoisomerase inhibitors
methotrexate(trexall)
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vincristine and methotrexate(trexall)
alemtuzumab
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vincristine and alemtuzumab
lomustine
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vincristine and lomustine
paclitaxel
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vincristine and paclitaxel
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web search results for 'vincristine'?
Results
1 - 50
- vincristine
Vincristine - Wikipedia, the free encyclopedia
... main side-effects of vincristine are peripheral neuropathy, hyponatremia, ... Severe vincristine neuropathy in Charcot-Marie-Tooth disease type 1A" ...
http://en.wikipedia.org/wiki/Vincristine
en.wikipedia.org
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summary
MedlinePlus Drug Information: Vincristine
Vincristine ... your doctor and pharmacist if you are allergic to vincristine or any other drugs. ... Vincristine may harm the fetus. ...
http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a682822.html
www.nlm.nih.gov
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Vincristine (Intravenous Route) - MayoClinic.com
Mayo Clinic offers award-winning medical and health information and tools for healthy living. ... Vincristine interferes with the growth of cancer cells, which ...
http://www.mayoclinic.com/health/drug-information/DR601433
www.mayoclinic.com
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summary
Vincristine
Drug details for Vincristine. ... Vincristine is only available as ... Vincristine should be administered only under the supervision of a medical oncologist. ...
http://www.webmd.com/cancer/vincristine
www.webmd.com
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vincristine medical facts from Drugs.com
Physician reviewed vincristine patient information - includes vincristine description, dosage and directions. ... side effects from treatment with vincristine. ...
http://www.drugs.com/mtm/vincristine.html
www.drugs.com
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VINCRISTINE - INJECTION (Oncovin, Vincasar) side effects, medical uses, and drug interactions.
Read more about the prescription drug VINCRISTINE - INJECTION. ... Fatalities have occurred when vincristine was injected into the spine. ...
http://www.medicinenet.com/vincristine-injection/article.htm
www.medicinenet.com
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Vincristine - Yahoo! Health
Vincristine should only be administered under the supervision of a qualified healthcare provider experienced in the use of cancer chemotherapeutic agents.
http://health.yahoo.com/cancer-medications/vincristine/healthwise--d00401a1.html
health.yahoo.com
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Oncovin (Vincristine Sulfate) drug description - prescription drugs and medications at RxList
Find Oncovin (Vincristine Sulfate) medication description and details on prescription drugs.
http://www.rxlist.com/cgi/generic3/vincristine.htm
www.rxlist.com
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Vincristine Sulfate
Vincristine is an alkaloid isolated from the leaves, bark or stem of the ... Differences between vinblastine and vincristine in distribution in the ...
http://dohs.ors.od.nih.gov/pdf/Vincristine%20sulfate%20REVISED%20_2_.pdf
dohs.ors.od.nih.gov
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summary
QSM/MC/IEA.115 18 July 2007 Information Exchange System Alert No. 115
Vincristine (and other vinca alkaloids) should only be given intravenously via a ... administration of vincristine via a spinal route continue to occur. ...
http://www.who.int/medicines/publications/drugalerts/Alert_115_vincristine.pdf
www.who.int
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summary
About - Health & Fitness - Drug Finder
VINCRISTINE (Oncovin®) is a cancer chemotherapy agent used for treating many ... Generic vincristine injections are available. ...
http://gsm.about.com/compact/showtext.asp?cpnum=646&monotype...
gsm.about.com
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summary
Penetration of intra-arterially administered vincristine in experimental brain tumor,
Vincristine is an integral part of the "PCV" regimen that is commonly ... was designed to determine whether vincristine enters normal rat brain or an ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1872009
www.pubmedcentral.nih.gov
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Vincristine Official FDA information, side effects and uses.
Accurate, FDA approved Vincristine information for healthcare professionals and patients - brought to ... administration of Vincristine Sulfate Injection, USP. ...
http://www.drugs.com/pro/Vincristine.html
www.drugs.com
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summary
Vincristine - Yahoo! Health
Vincristine is a plant-based compound and is classified as an alkylating agent. ... Vincristine should be administered only under the ... Vincristine ...
http://health.yahoo.com/cancer-medications/vincristine/healthwise--tv7048.html
health.yahoo.com
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NTP: ChemIDPlus/HSDB 57-22-7 Toxicity
ALOPECIA OCCURS IN ABOUT 20% OF PATIENTS GIVEN VINCRISTINE ... MAY OCCUR WITH VINCRISTINE, & THROMBOCYTOPENIA, ANEMIA, POLYURIA, ... Vincristine ...
http://ntp.niehs.nih.gov/index.cfm?objectid=E880EEC5-BDB5-82F8-F74790304662A4DB
ntp.niehs.nih.gov
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summary
Drugs and Treatments - Vincristine IV - Patient Handout from WebMD
Find information on WebMD including drug user ratings, drug interactions, medication warnings, medical uses, side effects and recommended dosage.
http://www.webmd.com/drugs/drug-7423-Vincristine+IV.aspx?dru...
www.webmd.com
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Talk:Vincristine - Wikipedia, the free encyclopedia
Vincristine is part of WikiProject Pharmacology, a project to improve all ... nervous system dysfunction as a result of the neurotoxic effect of vincristine. ...
http://en.wikipedia.org/wiki/Talk:Vincristine
en.wikipedia.org
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vincristine-injection Glossary of Terms with Definitions on MedicineNet.com
vincristine-injection glossary includes a list of vincristine-injection related medical definitions and related links on MedicineNet.com
http://www.medicinenet.com/vincristine-injection/glossary.htm
www.medicinenet.com
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Living with Cancer Chemotherapy
Vincristine prevents cancer cells from dividing by affecting the ... VIncristine (Oncovin. Living with Cancer Chemotherapy Series ...
http://www.cc.nih.gov/ccc/patient_education/CaTxeng/vincristine.pdf
www.cc.nih.gov
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[Thrombotic thrombocytopenic purpura achieving complete remission by slow infusion of vincristine]
... which was successfully treated by slow infusion of vincristine (VCR) is reported. ... Substances: Vincristine. PMID: 1404865 [PubMed - indexed for MEDLINE] ...
http://www.ncbi.nlm.nih.gov/pubmed/1404865
www.ncbi.nlm.nih.gov
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summary
Childhood Hodgkin Lymphoma Treatment - National Cancer Institute
Expert-reviewed information summary about the treatment of childhood Hodgkin ... COPP/ABV (cyclophosphamide, vincristine, procarbazine, prednisone/doxorubicin, ...
http://www.nci.nih.gov/cancertopics/pdq/treatment/childhodgk...
www.nci.nih.gov
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summary
Vincristine Sulfate Drug Information, Professional
Vincristine Sulfate Drug Information from Drugs.com. Includes Vincristine Sulfate side effects, interactions and indications.
http://www.drugs.com/mmx/vincristine-sulfate.html
www.drugs.com
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summary
Vincristine - Wikipédia
La vincristine (Oncovin) est un alcaloïde extrait de la pervenche de Madagascar ... La vincristine a pour effet d'empêcher la polymérisation des microtubules en se ...
http://fr.wikipedia.org/wiki/Vincristine
fr.wikipedia.org
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Bleomycin + vincristine/VP16 with or without G-CSF in AIDS patients with Kaposi's sarcoma.
... and toxicity of bleomycin with vincristine or VP16 as a chemotherapeutic regimen ... peripheral neuropathy were switched from vincristine to VP16 (100 mg/mm3 IV) ...
http://gateway.nlm.nih.gov/MeetingAbstracts/102217212.html
gateway.nlm.nih.gov
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summary
Search for vincristine on Yahoo! Health
Vincristine should only be administered under the supervision of a qualified ... Vincristine is a plant-based compound and is classified as an alkylating agent. ...
http://health.yahoo.com/search?p=vincristine&su=&fr=
health.yahoo.com
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summary
Multidrug Resistance-Associated Protein 1 (MRP1) mediated vincristine resistance: effects of N-acetylcysteine and ...
... of natural product drugs like vincristine, although the mechanisms have not been ... Vincristine is a vinca alcaloid type drug and a widely used chemotherapeutic ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pub...
www.pubmedcentral.nih.gov
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Vincristine Side Effects | Drugs.com
Comprehensive and accurate Vincristine side effects information for consumers and healthcare professionals. ... side effects for Vincristine may not be ...
http://www.drugs.com/sfx/vincristine-side-effects.html
www.drugs.com
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summary
Chemotherapy regimens - Wikipedia, the free encyclopedia
... (doxorubicin), cyclophosphamide, Oncovin (vincristine), procarbazine, prednisone ... doxorubicin (hydroxydoxorubicin), vincristine (Oncovin), prednisone ...
http://en.wikipedia.org/wiki/Chemotherapy_regimen
en.wikipedia.org
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Drugs and Treatments - Vincasar IV - Patient Handout from WebMD
Find information about (Vincasar IV) on WebMD including drug user ratings, drug interactions, medication warnings, medical ... If vincristine leaks out of the ...
http://www.webmd.com/drugs/drug-52904-Vincasar+IV.aspx?drugi...
www.webmd.com
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Definition of vincristine - NCI Dictionary of Cancer Terms
Novel Molecular Pattern Linked to Colon Cancer Prognosis ... vincristine. An anticancer drug that belongs to the family of plant drugs called vinca alkaloids. ...
http://www.nci.nih.gov/Templates/db_alpha.aspx?CdrID=45435
www.nci.nih.gov
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summary
Clinical Study: 04-C-0011, A Study of Combination Chemotherapy & Surgical Resection in the Tx of Adrenocortical ...
Clinical Study Summary ... Infusion Doxorubicin, Vincristine & Etoposide w/the ... Doxorubicin, vincristine, and etoposide will be continuously ...
http://clinicalstudies.info.nih.gov/detail/A_2004-C-0011.html
clinicalstudies.info.nih.gov
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summary
NTP: Testing Status: Vincristine C04864
... Testing Status of Agents at NTP >> Testing Status: Vincristine C04864 ... Vincristine. CAS Number: 57-22-7. Formula: C46 H56 N4 O10. Synonyms/Common Names: ...
http://ntp.niehs.nih.gov/index.cfm?objectid=BD36BC4E-123F-7908-7B5D3010FF90528A
ntp.niehs.nih.gov
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Vincristine facts and comparsions at Drugs.com
All about Vincristine. View complete and up to date Vincristine information - part of the Drugs.com trusted medication database.
http://www.drugs.com/cdi/vincristine.html
www.drugs.com
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drug guide: vincristine overview on yahoo! health
http://health.yahoo.com/drug/d00401a1
health.yahoo.com
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Chemotherapy regimens - Wikipedia, the free encyclopedia
... (doxorubicin), cyclophosphamide, Oncovin (vincristine), procarbazine, prednisone ... hydroxydoxorubicin (doxorubicin), vincristine (Oncovin), prednisone ...
http://en.wikipedia.org/wiki/Chemotherapy_regimens
en.wikipedia.org
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Hodgkin's disease, childhood: Treatment - Health Professional Information [NCI PDQ] -- Treatment Approach for ...
In general, the use of combined chemotherapy and radiation broadens the ... COPP/ABV (cyclophosphamide, vincristine, procarbazine, prednisone/doxorubicin, ...
http://www.webmd.com/hw/hodgkins_disease/ncicdr0000062933-tr...
www.webmd.com
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Vincristine (Oncovin
Vincristine (Oncovin. En el Centro Clínico es referide como Vincristine. ... La Vincristine evita que las células del cáncer se dividan ...
http://www.cc.nih.gov/ccc/patient_education/CaTxsp/vincristines.pdf
www.cc.nih.gov
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Oncovin (vincristine) medical facts from Drugs.com
Physician reviewed Oncovin patient information - includes Oncovin description, dosage and directions. ... possible side effects from treatment with vincristine. ...
http://www.drugs.com/mtm/oncovin.html
www.drugs.com
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NIOSH/Health Care Workers Guidelines/Chap5a (continued)
... C, nitrogen mustard, prednisone, procarbazine, streptomycin, and vincristine) ... drugs (e.g. methotrexate and vincristine) are skin and mucous membrane irritants ...
http://www.cdc.gov/niosh/hcwold5a.html
www.cdc.gov
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Complete Vincristine Sulfate information from Drugs.com
All about Vincristine Sulfate. View complete and up to date Vincristine Sulfate information - part of the Drugs.com trusted medication database.
http://www.drugs.com/ppa/vincristine-sulfate.html
www.drugs.com
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Clinical Trials (PDQ®) - National Cancer Institute
... to Procarbazine, Lomustine, and Vincristine in Treating Patients With Recurrent ... vs procarbazine, lomustine, and vincristine, in terms of overall survival, ...
http://www.nci.nih.gov/clinicaltrials/MRC-BR12
www.nci.nih.gov
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summary
Randomized comparative trial of DOXIL vs. Bleomycin and Vincristine in the treatment of AIDS-Related KS.
... trial of DOXIL vs. Bleomycin and Vincristine in the treatment of AIDS-Related KS. ... Bleomycin, 15 mg/m(2) and Vincristine 2 mgs (120 patients)or DOXIL-20 ...
http://gateway.nlm.nih.gov/MeetingAbstracts/102225475.html
gateway.nlm.nih.gov
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Wilms' Tumor and Other Childhood Kidney Tumors
... weeks of chemotherapy with vincristine, doxorubicin, and pulse-intensive ... with standard chemotherapy DD-4A (vincristine, dactinomycin, and doxorubicin) ...
http://www.webmd.com/cancer/tc/wilms-tumor-treatment-health-...
www.webmd.com
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Treatment of Wilms tumor relapsing after initial treatment with vincristine, actinomycin D, and doxorubicin. A ...
A report from the National Wilms Tumor Study Group. ... relapsed after chemotherapy with vincristine, actinomycin D, and doxorubicin ...
http://www.ncbi.nlm.nih.gov/pubmed/17539021?ordinalpos=12&it...
www.ncbi.nlm.nih.gov
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Natural Product Synthesis Special Feature: Stereocontrolled total synthesis of (+)-vincristine
... a related compound, vincristine methiodide, was then ... that both vinblastine (1) and vincristine (2) (5) are bisindole alkaloids, ... Vincristine (,2) ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=514417
www.pubmedcentral.nih.gov
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vincristine sulfate Information from Drugs.com
vincristine sulfate medical information ... Stedman's > vincristine sulfate. vincristine sulfate. Pronunciation: vin-kris?t?n s?l?f?t ...
http://www.drugs.com/dict/vincristine-sulfate.html
www.drugs.com
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Oncovin advanced consumer information | Drugs.com
Oncovin patient information - advanced edition from the United ... Vincristine interferes with the growth of cancer cells, which are eventually destroyed. ...
http://www.drugs.com/cons/Oncovin.html
www.drugs.com
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CHEMOTHERAPY-EVOKED PAINFUL PERIPHERAL NEUROPATHY: ANALGESIC EFFECTS OF GABAPENTIN AND EFFECTS ON EXPRESSION OF THE ...
... in both paclitaxel- and vincristine-evoked painful peripheral neuropathies (Siau ... paclitaxel-injection, and D17 after the first vincristine injection) ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pub...
www.pubmedcentral.nih.gov
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Gestational trophoblastic tumors: Treatment - Health Professional Information [NCI PDQ] -- Poor-Prognosis Metastatic...
Patients with any of the high - risk factors fall into this category. ... methotrexate-dactinomycin/cyclophosphamide-vincristine for high-risk gestational ...
http://www.webmd.com/hw/uterine_cervical_cancer/ncicdr000006...
www.webmd.com
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Vincasar PFS
Vincristine interferes with the growth of cancer cells and slows their growth ... Vincristine is used in the treatment of leukemia. ...
http://www.drugs.com/mtm/vincasar-pfs.html?printable=1
www.drugs.com
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