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thiotepa
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what is 'thiotepa'?
Definition for thiotepa
N,N'N'-triethylenethiophosphoramide , abbreviated "ThioTEPA," is an organophosphorus compound with the formula SP(NC 2 H 4 ) 3 . [ 1 ]
This cancer chemotherapeutic member of the alkylating agent group was characterized in 1953 [ 2 ] and has been in use for since the 1960s.
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N,N'N'-triethylenethiophosphoramide , abbreviated "ThioTEPA," is an organophosphorus compound with the formula SP(NC 2 H 4 ) 3 . [ 1 ]
This cancer chemotherapeutic member of the alkylating agent group was characterized in 1953 [ 2 ] and has been in use for since the 1960s. It is an analogue of N,N',N''- triethylenephosphoramide ( TEPA ).
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diagnoses treated with 'thiotepa'
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diagnosis
metastases
spread of malignant tumors to other body sites
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thiotepa and intracranial tumor
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cancer
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thiotepa and malignancy
ganglioglioma
benign brain tumor
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thiotepa and ganglioglioma
related procedures when taking 'thiotepa'
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procedures
Biopsy
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thiotepa and Biopsy
Brachytherapy
Sealed source radiotherapy
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thiotepa and Brachytherapy
Brain MRI
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thiotepa and Brain MRI
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CT scan
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Complete metabolic panel
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External Beam Radiation
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thiotepa and Lumbar Puncture
serum electrolytes
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Debulking of Tumor
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FDG PET scan
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thiotepa and FDG PET scan
Immunocytochemistry
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thiotepa and Immunocytochemistry
Targeted Fusion Protein Therapy
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thiotepa and Targeted Fusion Protein Therapy
Targeted therapies
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thiotepa and Targeted therapies
Urinalysis
Examination of urine to detect disease
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serum protein S-100 B
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thiotepa and serum protein S-100 B
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thiotepa and BUN
Liver Function Tests
elevated liver enzymes
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thiotepa and Liver Function Tests
Serum Creatinine
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thiotepa and Serum Creatinine
CT temporal bone(s)
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thiotepa and CT temporal bone(s)
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related medication for 'thiotepa'
1 - 5 of
80
drugs
cyclophosphamide
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thiotepa and cyclophosphamide
methotrexate
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thiotepa and methotrexate
temozolomide
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thiotepa and temozolomide
vincristine
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thiotepa and vincristine
carmustine (bcnu)
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thiotepa and carmustine (bcnu)
5-fluorouracil (5-fu)
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thiotepa and 5-fluorouracil (5-fu)
6-mercaptopurine (6-mp)
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thiotepa and 6-mercaptopurine (6-mp)
actinomycin-d
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thiotepa and actinomycin-d
alemtuzumab
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thiotepa and alemtuzumab
alkylating agents
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thiotepa and alkylating agents
altretamine
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anastrozole
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anti tumor antibiotics
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thiotepa and anti tumor antibiotics
antimetabolites
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arsenic trioxide
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bevacizumab
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thiotepa and bevacizumab
bexarotene
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thiotepa and bexarotene
bicalutamide
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bleomycin
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bortezomib
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The following are types of physicians relevant for 'thiotepa'.
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web search results for 'thiotepa'?
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- thiotepa
Thiotepa (Thiotepa Injection) Drug Information: Uses, Side Effects ...
Learn about the prescription medication Thiotepa (Thiotepa Injection), drug uses, dosage, side effects, drug interactions, warnings, and patient labeling.
http://www.rxlist.com/thiotepa-drug.htm
www.rxlist.com
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Thiotepa Official FDA information, side effects and uses.
Accurate, FDA approved Thiotepa information for healthcare professionals and patients - brought to you by Drugs.com. ... Thiotepa has the following structural ...
http://www.drugs.com/pro/thiotepa.html
www.drugs.com
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ThioTEPA - Wikipedia, the free encyclopedia
Urinary excretion of thioTEPA and its metabolites in patients treated with high ... Retrieved from "http://en.wikipedia.org/wiki/ThioTEPA" ...
http://en.wikipedia.org/wiki/ThioTEPA
en.wikipedia.org
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Thiotepa - Yahoo! Health
Thiotepa should only be administered under the supervision of a qualified healthcare provider experienced in the use of cancer chemotherapeutic agents.
http://health.yahoo.com/cancer-medications/thiotepa/healthwise--d00390a1.html
health.yahoo.com
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Thiotepa CAS No. 52-24-4
Thiotepa is known to be a human carcinogen based on sufficient ... experimental animals, which demonstrate that thiotepa is carcinogenic ...
http://ntp.niehs.nih.gov/ntp/roc/eleventh/profiles/s174thio.pdf
ntp.niehs.nih.gov
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Drug Information for Thiotepa Inj - WebMD
Find medical information for Thiotepa Inj including side effects, drug interactions, images and pictures, medication uses, warnings, user ratings and reviews.
http://www.webmd.com/drugs/drug-16346-Thiotepa+Inj.aspx?drug...
www.webmd.com
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THIOTEPA - INJECTION (Thioplex) side effects, medical uses, and drug ...
Read more about the prescription drug THIOTEPA - INJECTION. ... USES: Thiotepa is used to treat ... Thiotepa is not recommended for use during pregnancy. ...
http://www.medicinenet.com/script/main/art.asp?articlekey=44508
www.medicinenet.com
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Living with Cancer Chemotherapy
Thiotepa stops the growth of cancer cells by binding together ... ing thiotepa. 3. Mild headache or dizziness can occur within the first few. hours after ...
http://www.cc.nih.gov/ccc/patient_education/CaTxeng/thiotepa.pdf
www.cc.nih.gov
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MedlinePlus Drug Information: Thiotepa
Thiotepa ... tell your doctor and pharmacist if you are allergic to thiotepa or any other drugs. ... Thiotepa may harm the fetus. ...
http://www.nlm.nih.gov/medlineplus/druginfo/meds/a682821.html
www.nlm.nih.gov
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Thiotepa (Injection Route) - MayoClinic.com
Mayo Clinic offers award-winning medical and health information and tools for healthy living. ... Thiotepa interferes with the growth of cancer cells, which ...
http://www.mayoclinic.com/health/drug-information/DR601339/METHOD=print
www.mayoclinic.com
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Thiotepa: Drug Information Provided by Lexi-Comp: Merck Manual Professional
Hypersensitivity to thiotepa or any component of the formulation; pregnancy ... Administration of thiotepa over 30 minutes, 1 hour before infusion of ...
http://www.merck.com/mmpe/lexicomp/thiotepa.html
www.merck.com
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Definition of thiotepa - NCI Dictionary of Cancer Terms
The Nation's Investment in Cancer Research FY 2010 ... thiotepa. An anticancer drug that belongs to the family of drugs called alkylating agents. ...
http://www.nci.nih.gov/Templates/db_alpha.aspx?CdrID=45603
www.nci.nih.gov
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Thiotepa - PubChem Public Chemical Database
PubChem Compound Summary ... Thiotepa - Compound Summary (CID 5453) ... Thiotepa. Organic Chemicals. Organophosphorus Compounds. Organothiophosphorus Compounds ...
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=5453
pubchem.ncbi.nlm.nih.gov
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Sequential chemotherapy, high-dose thiotepa, circulating progenitor ...
... diagnosed malignant glioma of childhood, thiotepa has been used mostly in ... High-dose thiotepa does not have a "consolidation" role but can be a further ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1871624
www.pubmedcentral.nih.gov
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summary
High-dose chemotherapy with hematopoietic stem-cell rescue for high ...
... meter of body-surface area, 480 mg of thiotepa per square ... Thiotepa/administration & dosage. Substances: Antineoplastic Agents, Alkylating. Tamoxifen ...
http://www.ncbi.nlm.nih.gov/pubmed/12840087?ordinalpos=4&ito...
www.ncbi.nlm.nih.gov
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thiotepa medical facts from Drugs.com
Physician reviewed thiotepa patient information - includes thiotepa description, dosage and directions. ... possible side effects from treatment with thiotepa. ...
http://www.drugs.com/mtm/thiotepa.html
www.drugs.com
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User Reviews and Drug Ratings for Thiotepa Inj - WebMD
Read user ratings and reviews for Thiotepa Inj including side effects and drug interactions, medication effectiveness, ease of use and satisfaction.
http://www.webmd.com/drugs/drugreview-16346-Thiotepa+Inj.asp...
www.webmd.com
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THIOTEPA - INJECTION (Thioplex) side effects, medical uses, and drug ...
Read doctor-produced health and medical information written for you to make informed decisions ... View All 5 thiotepa-injection Doctor's & Expert's Views " ...
http://www.medicinenet.com/thiotepa-injection/index.htm
www.medicinenet.com
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ChemIDPlus/HSDB 52-24-4 Toxicity - National Toxicology Program
THIOTEPA MAY PRODUCE NAUSEA, ANOREXIA, & HEADACHE. ... IN 6 OF THE CASES, THIOTEPA WAS USED WITH OTHER CHEMOTHERAPEUTIC AGENTS &/OR RADIATION. ...
http://ntp.niehs.nih.gov/index.cfm?objectid=E88066EE-BDB5-82F8-FCD1AF32CC765D13
ntp.niehs.nih.gov
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summary
Conventional adjuvant chemotherapy with or without high-dose ...
Thiotepa/administration & dosage. Transplantation, Autologous. Substances: Tamoxifen ... Thiotepa. Grant Support: CA13650/CA/NCI NIH HHS/United States ...
http://www.ncbi.nlm.nih.gov/pubmed/12840088?ordinalpos=1&ito...
www.ncbi.nlm.nih.gov
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Thiotepa facts and comparsions at Drugs.com
All about Thiotepa. View complete and up to date Thiotepa information - part of the Drugs.com trusted medication database. ... Thiotepa may cause dizziness or ...
http://www.drugs.com/cdi/thiotepa.html
www.drugs.com
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Acute nonlymphocytic leukemia following bladder instillations with thiotepa.
Journal List > Can Med Assoc J > v.129(6); Sep 15, 1983. Summary. Selected ... of thiotepa (an alkylating agent), but this patient received only intravesical ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1875556
www.pubmedcentral.nih.gov
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Review your experience with Thiotepa Inj - WebMD
Rate your drug experience with Thiotepa Inj including side effects, drug interactions, effectiveness, ease of use and satisfaction.
http://www.webmd.com/drugs/drugreviewpost-16346-Thiotepa+Inj...
www.webmd.com
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Cyclophosphamide: Drug Information Provided by Lexi-Comp: Merck Manual ...
... bicarbonate, teniposide, thiotepa, ticarcillin, ticarcillin ... A 30-minute infusion of thiotepa administered 1 hour before a 60-minute infusion ...
http://www.merck.com/mmpe/lexicomp/cyclophosphamide.html
www.merck.com
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NIOSH/Health Care Workers Guidelines/Chap5a (continued)
The drugs of greatest concern are those associated with ... Thiotepa. Inadequate. Sufficient. T. Uracil mustard. Inadequate. Sufficient. T. Vinblastine ...
http://www.cdc.gov/niosh/hcwold5a.html
www.cdc.gov
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Aprepitant inhibits cyclophosphamide bioactivation and thiotepa metabolism.
... emetogenic high-dose chemotherapy regimen with cyclophosphamide, thiotepa and ... pharmacokinetics and metabolism of cyclophosphamide and thiotepa was evaluated. ...
http://www.ncbi.nlm.nih.gov/pubmed/15838656
www.ncbi.nlm.nih.gov
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Thioplex (thiotepa) medical facts from Drugs.com
Physician reviewed Thioplex patient information - includes Thioplex description, dosage and directions. ... possible side effects from treatment with thiotepa. ...
http://www.drugs.com/mtm/thioplex.html
www.drugs.com
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CRISP - Computer Retrieval of Information on Scientific Projects ...
... to establish, for doxorubicin and thiotepa, (a) drug concentration-time profiles ... cancer relapse /recurrence, prognosis, thiotepa, urinary bladder epithelium ...
http://crisp.cit.nih.gov/crisp/CRISP_LIB.getdoc?textkey=6512...
crisp.cit.nih.gov
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Intra-articular thiotepa in rheumatoid arthritis.
Intra-articular thiotepa in rheumatoid arthritis. H L Currey ... MEDICAL SYNOVECTOMY WITH THIOTEPA. Ann Phys Med. 1964 Nov;53:287?293. [PubMed] ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1030982
www.pubmedcentral.nih.gov
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Rotavirus Vaccine, Live (Oral Route) - MayoClinic.com
Mayo Clinic offers award-winning medical and health information ... Thiotepa. Topotecan. Treosulfan. Triamcinolone. Trimetrexate. Trofosfamide. Uracil Mustard ...
http://www.mayoclinic.com/health/drug-information/DR602619/DSECTION=before-using
www.mayoclinic.com
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summary
ChemIDplus Lite
Chemical Information Resources pointing to biomedical information, ChemIDplus structure/name file, HSDB structure ... Thiotepa [USAN:INN:BAN:JAN] RN: 52-24-4 ...
http://chem.sis.nlm.nih.gov/chemidplus/ProxyServlet?objectHa...
chem.sis.nlm.nih.gov
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Wellbutrin XL (Bupropion Hydrochloride Extended-Release) Drug ...
Learn about the prescription medication Wellbutrin XL (Bupropion Hydrochloride Extended-Release), drug uses, dosage, side ... orphenadrine, thiotepa, and ...
http://www.rxlist.com/cgi/generic/wellbutrinxl.htm
www.rxlist.com
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summary
Complete Thiotepa information from Drugs.com
All about Thiotepa. View complete and up to date Thiotepa information - part of the Drugs.com ... Thiotepa is a cell cycle nonspecific alkylating agent ...
http://www.drugs.com/ppa/thiotepa.html
www.drugs.com
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BUPROPION SUSTAINED RELEASE - ORAL (ANTIDEPRESSANT) (Wellbutrin) side ...
Consumer information about the medication BUPROPION SUSTAINED RELEASE - ORAL ... flecainide), orphenadrine, thiotepa, cyclophosphamide, carbamazepine, ...
http://www.medicinenet.com/bupropion_sustained_release-oral/page3.htm
www.medicinenet.com
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Combined treatment of metastatic breast cancer (MBC) by high-dose ...
... ET, responders (CR/PR) underwent HDCT (thiotepa 600 mg/m2/melphalan 140-180 mg/m2) and ASCT. ... Paclitaxel. Ifosfamide. Thiotepa. Epirubicin. PMID: ...
http://www.ncbi.nlm.nih.gov/pubmed/16080564?dopt=Abstract
www.ncbi.nlm.nih.gov
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Effects of single, short term exposures of human retinal pigment ...
... RPE cells in collagen lattices to the highest concentration of thiotepa (4 mg/ml) ... Effect of exposure to thiotepa (A and B) or 5-FU (C and D) on RPE cell ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1722588
www.pubmedcentral.nih.gov
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Thiotepa - National Toxicology Program
Primary Uses or Exposures: Thiotepa is u sed as a cytostatic agent in the ... Basis for Nomination: NTP Bioassay (TR-058) and IARC1 classification as ...
http://ntp.niehs.nih.gov/INDEX.CFM?OBJECTID=BE67A5F0-F1F6-975E-70841A2F3314E344
ntp.niehs.nih.gov
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summary
Rubella Virus Vaccine, Live (Subcutaneous Route) - MayoClinic.com
Mayo Clinic offers award-winning medical and health information ... Thiotepa. Topotecan. Treosulfan. Trimetrexate. Trofosfamide. Uracil Mustard. Vinblastine ...
http://www.mayoclinic.com/health/drug-information/DR601221/DSECTION=before-using
www.mayoclinic.com
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Effect of Vancomycin on the Incidence of Early S. viridans Bacteremia ...
... with total body irradiation (TBI) 65.4%, (TBI/thiotepa/fludarabine 14.9 ... 2) Conditioning with TBI/Thiotepa/fludarabine (HR 6.1) and CML (HR 2.2) remained ...
http://gateway.nlm.nih.gov/MeetingAbstracts/ma?f=102264757.html
gateway.nlm.nih.gov
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BUPROPION EXTENDED RELEASE - ORAL (ANTIDEPRESSANT) (Wellbutrin XL) side ...
Consumer information about the medication BUPROPION EXTENDED RELEASE - ORAL ... flecainide), orphenadrine, thiotepa, cyclophosphamide, carbamazepine, ...
http://www.medicinenet.com/bupropion_extended_release-oral/page3.htm
www.medicinenet.com
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PMID 16330449
... 51264-14-3 Amsacrine 52-24-4 Thiotepa 5536-17-4 Vidarabine 58957-92-9 Idarubicin ... Therapy Survival Analysis Thiotepa administration & dosage Topotecan ...
http://www.ncbi.nlm.nih.gov/pubmed/16330449
www.ncbi.nlm.nih.gov
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Drugs A-Z List - T on RxList
Browse an A-Z list of Brand and Generic drugs to learn about your ... Thiotepa (Thiotepa Injection) Thiotepa Injection (Thiotepa) Thiothixene Hcl (Navane) ...
http://www.rxlist.com/script/main/alphaidx.asp?subject=drugs&p=t
www.rxlist.com
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Th - Ti index - Drugs.com
Browse drugs and medications alphabetically. Includes Therevac-SB, Thermazene, thiabendazole, ... thiotepa. Thiotepa. Thiotepa. Thiotepa. Thiotepa ...
http://www.drugs.com/alpha/t8.html
www.drugs.com
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CYP2B6 - Wikipedia, the free encyclopedia
Along with CYP2A6, it is involved with metabolizing nicotine, ... thiotepa (Alkylating antineoplastic agent) ticlopidine (antiplatelet) Often mentioned [1] ...
http://en.wikipedia.org/wiki/CYP2B6
en.wikipedia.org
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Committee Recommendations: Thiotepa - National Toxicology Program
... on Carcinogens " 11th RoC and earlier " Committee Recommendations: Thiotepa ... Committee Recommendations: Thiotepa. Print this page Easy Link. http://ntp. ...
http://ntp.niehs.nih.gov/index.cfm?objectid=D3DB94D3-F1F6-975E-7598546BE0989585
ntp.niehs.nih.gov
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Martinoni A, Cipolla CM, Civelli M et al.
... or cytostatic activity, like tetracyclines, bleomycin, thiotepa or radionuclides. ... thiotepa is the best compromise in terms of recurrence prevention, ...
http://www.ncbi.nlm.nih.gov/pubmed/11200128
www.ncbi.nlm.nih.gov
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MedlinePlus Drug Information: Drugs beginning with Ta
Tanafed® (as a combination product containing Chlorpheniramine ... Thiotepa. Thiothixene. Thorazine® see Chlorpromazine. Thyroid. thyroid extract see Thyroid ...
http://www.nlm.nih.gov/medlineplus/druginfo/drug_Ta.html
www.nlm.nih.gov
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Cancer (Malignant Tumor) Types, Facts, Survival Rates, Statistics and ...
Information on many different cancers includes symptoms, cancer detection ... thiotepa. Trisenox. Valstar. Velcade. Vepesid. Vinblastine Sulfate. Vincasar PFS ...
http://www.medicinenet.com/script/main/forum.asp?articlekey=...
www.medicinenet.com
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Zyban (Bupropion Hcl) Drug Information: Uses, Side Effects, Drug ...
Learn about the prescription medication Zyban (Bupropion Hcl), drug uses, ... of the CYP2B6 isoenzyme (e.g., orphenadrine, thiotepa, and cyclophosphamide) ...
http://www.rxlist.com/zyban-drug.htm
www.rxlist.com
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14 May 1998: 15 Drugs, Dyes and Other Chemicals Newly Listed As Known ...
NTP announced the addition of 14 substancesincluding several diesel combustion productsto the 184 already included in the ... THIOTEPA, a drug used to treat ...
http://www.niehs.nih.gov/news/releases/news-archive/1998/carcin8.cfm
www.niehs.nih.gov
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