Quazepam (marketed under brand names Doral , Dormalin ) is a drug which is a benzodiazepine derivative. Quazepam is indicated for the treatment of insomnia including sleep induction and sleep maintenance. more

Quazepam (marketed under brand names Doral , Dormalin ) is a drug which is a benzodiazepine derivative. Quazepam is indicated for the treatment of insomnia including sleep induction and sleep maintenance. [ 1 ] Quazepam induces impairment of motor function and has hypnotic and anticonvulsant properties with less overdose potential than other benzodiazepines. [ 2 ] [ 3 ] Quazepam is an effective hypnotic which induces and maintains sleep without disruption of the sleep architecture . [ 4 ] Quazepam is a trifluoroethyl type of benzodiazepine. Quazepam is unique amongst benzodiazepines in that it selectively targets the GABA A type1 receptors which are responsible for inducing sleep. Its mechanism of action is very similar to zolpidem and zaleplon in its pharmacology and can successfully substitute for zolpidem and zaleplon in animal studies. [ 5 ] [ 6 ] [ 7 ] Quazepam is manufactured by the pharmaceutical corporation Schering-Plough . [ 8 ] less