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psoralen
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what is 'psoralen'?
Definition for psoralen
Psoralen (also called psoralene ) is the parent compound in a family of natural products known as furocoumarins . It is structurally related to coumarin by the addition of a fused furan ring, and may be considered as a derivative of umbelliferone .
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Psoralen (also called psoralene ) is the parent compound in a family of natural products known as furocoumarins . It is structurally related to coumarin by the addition of a fused furan ring, and may be considered as a derivative of umbelliferone . Psoralen occurs naturally in the seeds of Psoralea corylifolia , as well as in the common Fig , celery , parsley and West Indian satinwood . It is widely used in PUVA (=Psoralen +UVA) treatment for psoriasis , eczema and vitiligo . Although safe to mammals, it should be used with care since many furocoumarins are extremely toxic to fish, and some are indeed used in streams in Indonesia to catch fish.
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diagnoses treated with 'psoralen'
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diagnosis
graft versus host reaction
complication of organ transplantation
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psoralen and graft versus host reaction
related procedures when taking 'psoralen'
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36
procedures
Arterial Blood Gas
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psoralen and Arterial Blood Gas
Biopsy
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psoralen and Biopsy
Biopsy liver
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psoralen and Biopsy liver
Biopsy skin
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psoralen and Biopsy skin
Blood, Platelet Count
Platelet Count
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psoralen and Blood, Platelet Count
CT chest
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psoralen and CT chest
CT scan
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psoralen and CT scan
Cardiac monitoring
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psoralen and Cardiac monitoring
Central venous catheter
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psoralen and Central venous catheter
Chest X-ray
Radiological technique to image the chest
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psoralen and Chest X-ray
Complete Blood Count
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psoralen and Complete Blood Count
Complete metabolic panel
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psoralen and Complete metabolic panel
Endoscopy
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psoralen and Endoscopy
Endoscopy, Upper Gastrointestinal
Endoscopy
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psoralen and Endoscopy, Upper Gastrointestinal
Hepatic ultrasonography
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psoralen and Hepatic ultrasonography
Immunosuppressive therapy
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psoralen and Immunosuppressive therapy
Intravenous infusion of immunoglobulin (IVIG)
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psoralen and Intravenous infusion of immunoglobulin (IVIG)
Irradiation of all blood products
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psoralen and Irradiation of all blood products
Liver Function Tests
elevated liver enzymes
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psoralen and Liver Function Tests
Oxygen
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psoralen and Oxygen
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related medication for 'psoralen'
1 - 5 of
40
drugs
antithymocyte globulin
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psoralen and antithymocyte globulin
alemtuzumab
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psoralen and alemtuzumab
alemtuzumab(campath )
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psoralen and alemtuzumab(campath )
anakinra
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psoralen and anakinra
artificial saliva
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psoralen and artificial saliva
artificial tears
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psoralen and artificial tears
azathioprine
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psoralen and azathioprine
azathioprine(imuran)
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psoralen and azathioprine(imuran)
clofazimine
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psoralen and clofazimine
cyclosporine
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psoralen and cyclosporine
cyclosporine(neoral)
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psoralen and cyclosporine(neoral)
daclizumab(zenapax )
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psoralen and daclizumab(zenapax )
denileukin diftitox
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psoralen and denileukin diftitox
denileukin diftitox(ontak )
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psoralen and denileukin diftitox(ontak )
immune globulin intravenous(gammagard)
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psoralen and immune globulin intravenous(gammagard)
infliximab
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psoralen and infliximab
infliximab(remicade )
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psoralen and infliximab(remicade )
methotrexate
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psoralen and methotrexate
methotrexate(trexall)
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psoralen and methotrexate(trexall)
methoxsalen(8-mop , oxsoralen-ultra)
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psoralen and methoxsalen(8-mop , oxsoralen-ultra)
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The following are types of physicians relevant for 'psoralen'.
related types of physicians 'dermatologist, family practitioner, gastroenterologist, hematologist, immunologist, internist, nephrologist, pulmonary critical care, pulmonologist'
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web search results for 'psoralen'?
Results
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- psoralen
Psoralen - Wikipedia, the free encyclopedia
Psoralen (also called psoralene) is the parent compound in a family of natural ... Should subjects who used psoralen suntan activators be screened for melanoma? ...
http://en.wikipedia.org/wiki/Psoralen
en.wikipedia.org
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Definition of psoralen - NCI Dictionary of Cancer Terms
psoralen (SOR-uh-len) ... Psoralen is a type of furocoumarin. An ... psoralen and ultraviolet A therapy, psoriasis, psychiatrist, psychological, psychologist ...
http://www.nci.nih.gov/Templates/db_alpha.aspx?CdrID=44900
www.nci.nih.gov
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Vitiligo Symptoms, Causes, Pigmentation Loss Treatment and Diagnosis on ...
Learn about the symptoms, diagnosis, research and treatment of vitiligo, an incurable disorder that causes white ... Topical psoralen photochemotherapy?often ...
http://www.medicinenet.com/vitiligo/page4.htm
www.medicinenet.com
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psoralen Information from Drugs.com
psoralen medical information ... Or browse a complete list of drug names A B C D E F G H I J K L M ... Stedman's > psoralen. psoralen. Pronunciation: s?r??-len ...
http://www.drugs.com/dict/psoralen.html
www.drugs.com
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Repairing the Sickle Cell mutation. II. Effect of psoralen linker ...
Third strand-directed psoralen modification, for example, has been used to ... Thus, psoralen adduct formation generally leads to base changes at the adduct ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=169896
www.pubmedcentral.nih.gov
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Psoralen and UVA light therapy (PUVA) for psoriasis
Drug details for Psoralen and UVA light therapy (PUVA) for psoriasis. ... A psoralen medication is taken 1½ to 2 hours before you are exposed to ...
http://www.webmd.com/skin-problems-and-treatments/psoriasis/...
www.webmd.com
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HHE Report No. HETA-86-0246-1736, Roths Foodliners, Albany Oregon
Contact with psoralen-containing produce items followed by ultraviolet (UVA) ... A similar, but less dramatic, difference was noted in the psoralen ...
http://www.cdc.gov/niosh/hhe/reports/pdfs/1986-0246-1736.pdf
www.cdc.gov
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Psoralen and UVA light therapy (PUVA) for psoriasis - Yahoo! Health
Pills, lotions, or bath salts ... Psoralen and UVA light therapy (PUVA) for ... A psoralen medication is taken 1½ to 2 hours before you are exposed to ...
http://health.yahoo.com/skinconditions-medications/psoralen-...
health.yahoo.com
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Talk:Psoralen - Wikipedia, the free encyclopedia
Psoralen is within the scope of WikiProject Chemicals, a daughter project of ... Retrieved from "http://en.wikipedia.org/wiki/Talk:Psoralen" ...
http://en.wikipedia.org/wiki/Talk:Psoralen
en.wikipedia.org
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Ultraviolet exposure as the main initiator of p53 mutations in basal ...
In psoralen and ultraviolet A-treated psoriatic patients, basal cell carcinomas ... site of psoralen binding and mutagenesis in cell and murine studies), and one (8 ...
http://www.ncbi.nlm.nih.gov/pubmed/11511317
www.ncbi.nlm.nih.gov
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Processing of targeted psoralen cross-links in Xenopus oocytes.
Psoralen cross-links have been shown to be both mutagenic and recombinagenic in ... The fate of plasmids containing psoralen adducts was evaluated in Xenopus ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=232518
www.pubmedcentral.nih.gov
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psoralen
Close Print this page. psoralen. Pronunciation: s?r??-len. A phototoxic drug used by topical or oral administration for the treatment of ...
http://www.drugs.com/dict/psoralen.html?printable=1
www.drugs.com
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Vitiligo: Treatments and drugs - MayoClinic.com
Vitiligo ? Comprehensive overview covers causes, symptoms and treatments of this skin pigment condition. ... Topical psoralen plus ultraviolet A (PUVA) ...
http://www.mayoclinic.com/health/vitiligo/DS00586/DSECTION=treatments-and-drugs
www.mayoclinic.com
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Photochemotherapy (PUVA) for atopic dermatitis
Photochemotherapy, or PUVA, is a combination of ultraviolet A (UVA) light therapy and a psoralen medication, which makes the skin more sensitive to the ultraviolet ...
http://www.webmd.com/skin-problems-and-treatments/eczema/pho...
www.webmd.com
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Questions and Answers about Vitiligo
Oral psoralen photochemotherapy?used for people with extensive vitiligo ... Known side effects of oral psoralen include sunburn, nausea and vomiting, ...
http://www.niams.nih.gov/Health_Info/Vitiligo/default.asp
www.niams.nih.gov
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Psoralen synthase - Wikipedia, the free encyclopedia
In enzymology, a psoralen synthase (EC 1.14.13.102) is an enzyme that catalyzes ... marmesin + NADPH + H+ + O2 psoralen + NADP+ + acetone + 2 H2O ...
http://en.wikipedia.org/wiki/Psoralen_synthase
en.wikipedia.org
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Psoriasis
Psoralen reaches the skin through the bloodstream, where it increases the skin's ... Topical preparations of psoralen are alternatives to oral forms. ...
http://adam.about.com/reports/000087_8.htm
adam.about.com
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Should subjects who used psoralen suntan activator...[Ann Oncol. 1997 ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and other life science journals for biomedical ...
http://www.ncbi.nlm.nih.gov/pubmed/9233521
www.ncbi.nlm.nih.gov
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Definition of psoralen and ultraviolet A therapy - NCI Dictionary of ...
The patient receives psoralen (a drug that becomes active when it is exposed to ... Psoralen and ultraviolet A therapy may increase the risk of getting skin cancer. ...
http://www.nci.nih.gov/templates/db_alpha.aspx?print=1&cdrid=439423
www.nci.nih.gov
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Specificity of site directed psoralen addition to RNA.
Light-induced cross-linking of DNA in the presence of a furocoumarin (psoralen) ... Interaction of psoralen-derivatized oligodeoxyribonucleoside methylphosphonates ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=317780
www.pubmedcentral.nih.gov
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PUVA - Wikipedia, the free encyclopedia
PUVA is a Psoralen + UVA treatment for Eczema, Psoriasis ... The Psoralen is applied or taken orally to sensitize the skin, then the skin is exposed to UVA. ...
http://en.wikipedia.org/wiki/PUVA
en.wikipedia.org
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Site-directed gene mutation at mixed sequence targets by psoralen ...
We show that psoralen-conjugated pcPNAs can deliver site-specific photoadducts ... Most of the induced psoralen-pcPNA mutations were single-base substitutions and ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2190703
www.pubmedcentral.nih.gov
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Tanning activator - Wikipedia, the free encyclopedia
Psoralen has been present in sunscreens in order to allow suntanning despite the ... Should subjects who used psoralen suntan activators be screened for melanoma? ...
http://en.wikipedia.org/wiki/Tanning_activator
en.wikipedia.org
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Definition of psoralen and ultraviolet A therapy - NCI Dictionary of ...
The patient receives psoralen (a drug that becomes active when it ... PSA failure, psammoma body, PSC 833, pseudomyxoma peritonei, psoralen. Next Definitions: ...
http://www.nci.nih.gov/Templates/db_alpha.aspx?CdrID=439423
www.nci.nih.gov
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Characteristics of triplex-directed photoadduct formation by psoralen ...
The attached psoralen has been found to intercalate at the triplex-duplex ... We have shown that the psoralen will bind at the junction even when there is a ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=307381
www.pubmedcentral.nih.gov
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Comparison of oral psoralen-UV-A with a portable tanning unit at home ...
... psoralen-UV-A in patients with chronic hand eczema: an open-label randomized ... OBJECTIVE: To study whether oral psoralen-UV-A (PUVA) with a portable tanning ...
http://www.ncbi.nlm.nih.gov/pubmed/15611423
www.ncbi.nlm.nih.gov
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Human MLH1 Protein Participates in Genomic Damage Checkpoint Signaling ...
Psoralen ICLs can result in mutations near the crosslinked ... Studies reveal that ATM and ATR may function as sensors in response to psoralen ICL exposure. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2526179
www.pubmedcentral.nih.gov
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Psoralen - PubChem Public Chemical Database
PubChem Compound Summary ... Psoralen - Substance Summary (SID: 11496) A naturally occurring furocoumarin, found in PSORALEA. ...
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=11496
pubchem.ncbi.nlm.nih.gov
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Triple-Helix Formation Induces Recombination in Mammalian Cells via a ...
We previously demonstrated that psoralen adducts targeted by triple-helix ... Photo-induced psoralen interstrand cross-links, and to a lesser extent ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=85216
www.pubmedcentral.nih.gov
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Preparation and characterization of biotinylated psoralen.
As do other psoralen derivatives, BPsor photoreacts with DNA to form interstrand ... Comparison of synthetic psoralen derivatives and 8-MOP in the inhibition of ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=338404
www.pubmedcentral.nih.gov
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hMutS? Is Required for the Recognition and Uncoupling of Psoralen ...
Here, we show that processing of psoralen ICLs in mammalian cell extracts is ... Plasmids and psoralen interstrand cross-linked substrates for the cross-link ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=133700
www.pubmedcentral.nih.gov
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Molecular cloning and functional characterization ...[J Biol Chem. 2007 ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 ... Psoralen synthase catalyzes a unique carbon-chain cleavage reaction ...
http://www.ncbi.nlm.nih.gov/pubmed/17068340
www.ncbi.nlm.nih.gov
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Guttate Psoriasis
Guttate psoriasis is a type of psoriasis that looks like small, salmon-pink drops on the skin. ... Psoralen drugs make the skin sensitive to the sun. ...
http://www.webmd.com/skin-problems-and-treatments/psoriasis/...
www.webmd.com
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Removal of psoralen monoadducts and crosslinks by human cell free extracts.
Psoralen ... Use of psoralen-modified oligonucleotides to trap ... Photochemical production of psoralen - DNA monoadducts capable of ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=328701
www.pubmedcentral.nih.gov
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In vivo persistence of DNA triple helices containing psoralen ...
... Bredberg A. Repair of triple helix directed psoralen adducts in human cells. ... Removal of thymine dimer and psoralen monoadduct by HeLa cell-free extract and ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=146337
www.pubmedcentral.nih.gov
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Permeability of Psoralen Derivatives in Lipid Membranes
Psoralen compounds (furocoumarins) have been used in photochemical treatment of, ... ( b) Snapshots from simulations showing psoralen (encircled) at its minimum and ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1562374
www.pubmedcentral.nih.gov
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DNA damage-dependent transcriptional arrest and termination of RNA ...
Our results indicate that psoralen crosslink in the template strand efficiently ... a model system, we introduced psoralen adducts in a DNA template containing ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=21219
www.pubmedcentral.nih.gov
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Psoralen covalently linked to oligodeoxyribonucleotides: synthesis ...
Wavelength dependence for the photoreactions of DNA-psoralen monoadducts. ... Interaction of psoralen-derivatized oligodeoxyribonucleoside methylphosphonates ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=331551
www.pubmedcentral.nih.gov
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Nucleosome positioning at the replication fork
... of sites of psoralen intercalation revealed that nucleosomes ... MNase digestion of isolated nuclei confirmed the result obtained by psoralen cross-linking. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=125336
www.pubmedcentral.nih.gov
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Orally administered Polypodium leucotomos extract decreases psoralen ...
... leucotomos extract decreases psoralen-UVA-induced phototoxicity, ... BACKGROUND: The use of psoralen-UVA (PUVA) in patients of skin phototype I to II ...
http://www.ncbi.nlm.nih.gov/pubmed/14699363?dopt=Abstract
www.ncbi.nlm.nih.gov
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Methods for the large-scale synthesis of psoralen furan-side ...
Structure of a psoralen cross-linked DNA in solution by nuclear magnetic resonance. ... Use of psoralen-modified oligonucleotides to trap three-stranded RecA-DNA ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?&artid=49113
www.pubmedcentral.nih.gov
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Solution structure of oligonucleotides covalently linked to a psoralen ...
Psoralen-deoxyribonucleic acid photoreaction. ... Interaction of psoralen-derivatized oligodeoxyribonucleoside methylphosphonates ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=306761
www.pubmedcentral.nih.gov
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Platelet-Activating Factor Is Crucial in Psoralen and Ultraviolet ...
Psoralen plus UVA (PUVA) is used as a very effective treatment modality for ... Psoralen and UVA (PUVA) photochemotherapy consists of the topical or oral ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1579250
www.pubmedcentral.nih.gov
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Evidence for structural deformation of the DNA helix by a psoralen ...
Wavelength dependence for the photoreactions of DNA-psoralen monoadducts. ... Structure of a psoralen cross-linked DNA in solution by nuclear magnetic resonance. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=338644
www.pubmedcentral.nih.gov
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Psoralen inactivation of influenza and herpes simplex viruses and of ...
Light-induced cross-linking of DNA in the presence of a furocoumarin (psoralen) ... Binding of psoralen derivatives to DNA and chromatin: influence of the ionic ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=351582
www.pubmedcentral.nih.gov
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Defective replication of psoralen adducts detected at the gene-specific ...
Using psoralen photoaddition as prototype DNA damage and the renaturing agarose ... In addition, analysis of psoralen-mediated DNA cross-linking in the rRNA genes ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=358985
www.pubmedcentral.nih.gov
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The effects of covalent additions of a psoralen on transcription by E ...
Wavelength dependence for the photoreactions of DNA-psoralen monoadducts. ... Psoralen-DNA crosslink repair in human lymphocytes. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=306179
www.pubmedcentral.nih.gov
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Phototherapy for psoriasis
Phototherapy is the use of ultraviolet (UV) light to slow the rapid growth of new ... Psoralen and UVA light therapy (PUVA), which combines UVA exposure and a ...
http://www.webmd.com/skin-problems-and-treatments/psoriasis/...
www.webmd.com
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Uncoupling of the recBC ATPase from DNase by DNA Crosslinked with Psoralen
The psoralen-DNA is not a potent inhibitor, but competes with single-stranded ... Light-induced cross-linking of DNA in the presence of a furocoumarin (psoralen) ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=389661
www.pubmedcentral.nih.gov
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Action mechanism of ABC excision nuclease on a DNA substrate containing ...
Light-induced cross-linking of DNA in the presence of a furocoumarin (psoralen) ... Psoralen plus near ultraviolet light inactivation of cultured Chinese hamster ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=386870
www.pubmedcentral.nih.gov
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