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what is 'pleconaril'? Definition for pleconaril Pleconaril is an antiviral drug being developed by Schering-Plough for prevention of asthma exacerbations and common cold symptoms in asthmatic subjects exposed to picornavirus respiratory infections. more Pleconaril is an antiviral drug being developed by Schering-Plough for prevention of asthma exacerbations and common cold symptoms in asthmatic subjects exposed to picornavirus respiratory infections. [ 1 ] Although the formulation used by Schering-Plough is a nasal spray , pleconaril is orally bioavailable , and is active against viruses in the Picornaviridae family, including Enterovirus [ 2 ] and Rhinovirus . [ 3 ] less diagnoses treated with 'pleconaril' 1 - 2 of 2 diagnosis enteroviral infections type of viral infection web search for: pleconaril and enteroviral infections ECHO virus infections web search for: pleconaril and ECHO virus infections related procedures when taking 'pleconaril' 1 - 5 of 26 procedures Intravenous (IV) lactated Ringer (LR) solution web search for: pleconaril and Intravenous (IV) lactated Ringer (LR) solution Intravenous (IV) normal saline (NS) web search for: pleconaril and Intravenous (IV) normal saline (NS) 4-fold increase in serum antibody titers web search for: pleconaril and 4-fold increase in serum antibody titers BUN web search for: pleconaril and BUN Blood, Platelet Count Platelet Count web search for: pleconaril and Blood, Platelet Count Cardiac enzymes web search for: pleconaril and Cardiac enzymes Cerebrospinal Fluid PCR web search for: pleconaril and Cerebrospinal Fluid PCR Cerebrospinal Fluid analysis web search for: pleconaril and Cerebrospinal Fluid analysis Cerebrospinal Fluid immunoglobulin M web search for: pleconaril and Cerebrospinal Fluid immunoglobulin M Cerebrospinal Fluid immunoglobulins web search for: pleconaril and Cerebrospinal Fluid immunoglobulins Cerebrospinal Fluid opening pressure web search for: pleconaril and Cerebrospinal Fluid opening pressure Complete Blood Count web search for: pleconaril and Complete Blood Count Complete metabolic panel web search for: pleconaril and Complete metabolic panel ECHOcardiogram web search for: pleconaril and ECHOcardiogram EKG Electrocardiogram web search for: pleconaril and EKG Electrolyte Administration web search for: pleconaril and Electrolyte Administration Intravenous (IV) fluids web search for: pleconaril and Intravenous (IV) fluids Lumbar Puncture web search for: pleconaril and Lumbar Puncture Polymerase Chain Reaction (PCR) web search for: pleconaril and Polymerase Chain Reaction (PCR) Reverse transcription polymerase chain reaction (RT-PCR) web search for: pleconaril and Reverse transcription polymerase chain reaction (RT-PCR) for more please login, login is free (click to login) related medication for 'pleconaril' 1 - 2 of 2 drugs acetaminophen web search for: pleconaril and acetaminophen ibuprofen web search for: pleconaril and ibuprofen The following are types of physicians relevant for 'pleconaril'. related types of physicians 'family practitioner, infectious disease specialist, internist' show local physicians postal code Find Local stars represent relevance to topic not rating more The results are computer generated suggestions to help you find a physician. MEDgle does not recommend any particular type of physician or claim to be complete or accurate in the providers and specialties suggested. web search results for 'pleconaril'? Results 1 - 50 - pleconaril Pleconaril - Wikipedia, the free encyclopedia a b "Effects of Pleconaril Nasal Spray on Common Cold ... Activity of pleconaril against enteroviruses" ... Pleconaril, a novel antipicornaviral agent" ... http://en.wikipedia.org/wiki/Pleconaril   en.wikipedia.org - summary Single-Dose Pharmacokinetics of a Pleconaril (VP63843) Oral Solution in ... Pleconaril is an orally active, broad-spectrum antipicornaviral agent which ... Pleconaril was well tolerated by all subjects. ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=89172   www.pubmedcentral.nih.gov - summary Pleconaril -- Cure For the Common Cold? There is a lot of buzz about pleconaril, a new drug that makes a runny nose ... Pleconaril -- Cure For the Common Cold? By Alan Greene, MD, FAAP ... http://www.webmd.com/cold-and-flu/pleconaril-cure-for-common-cold   www.webmd.com - summary Efficacy and safety of oral pleconaril for treatme...[Clin Infect Dis ... PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and other life science journals for biomedical ... http://www.ncbi.nlm.nih.gov/pubmed/12802751   www.ncbi.nlm.nih.gov - summary Pleconaril - PubChem Public Chemical Database PubChem Compound Summary ... Pleconaril - Compound Summary (CID: 1684) structure in first source. Table of Contents ... pleconaril. Pharmacological Action ... http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=1684   pubchem.ncbi.nlm.nih.gov - summary Pleconaril Treatment Shortens Duration of Picornavirus Respiratory ... Pleconaril Treatment Shortens Duration of Picornavirus Respiratory Illness in Adults. ... In this same group, pleconaril treated subjects experienced a ... http://gateway.nlm.nih.gov/MeetingAbstracts/ma?f=102246428.html   gateway.nlm.nih.gov - summary Antiviral Agents and Polio Eradication | CDC EID In clinical studies, pleconaril was a promising candidate for treating the ... Treatment of potentially life-threatening enterovirus infections with pleconaril. ... http://www.cdc.gov/eid/content/14/4/545.htm   www.cdc.gov - summary Relationship of Pleconaril Susceptibility and Clinical Outcomes in ... Pleconaril, a specific inhibitor of human picornaviruses, showed therapeutic ... Pleconaril treatment was associated with a more rapid loss of culturable virus. ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pub...   www.pubmedcentral.nih.gov - summary Talk:Pleconaril - Wikipedia, the free encyclopedia Pleconaril is part of WikiProject ... BMJ news article on the pleconaril media frenzy ... Retrieved from "http://en.wikipedia.org/wiki/Talk:Pleconaril" ... http://en.wikipedia.org/wiki/Talk:Pleconaril   en.wikipedia.org - summary Structure Summary, 1NCR, 25607 MMDB is a database of three-dimensional biomolecular structure at the ... Pleconaril is a broad-spectrum antirhinovirus and antienterovirus compound that ... http://www.ncbi.nlm.nih.gov/Structure/mmdb/mmdbsrv.cgi?uid=25607   www.ncbi.nlm.nih.gov - summary Pleconaril Is Effective for Enteroviral Meningitis in Adolescents and ... Pleconaril is a first-of-a-kind orally bioavailable antiviral agent that ... Pleconaril has previously demonstrated activity in enteroviral meningitis in children. ... http://gateway.nlm.nih.gov/MeetingAbstracts/ma?f=102245676.html   gateway.nlm.nih.gov - summary eMedicine - Echovirus : Article by Jorge M Quinonez Echoviruses (EVs) are RNA viruses of the genus Enterovirus and the family Picornaviridae. ... Effects of Pleconaril Nasal Spray on Common Cold Symptoms and Asthma ... http://www.emedicine.com/ped/topic649.htm   www.emedicine.com - summary Single-Dose Pharmacokinetics of a Pleconaril (VP63843) Oral Solution ... Pleconaril is an orally active broad-spectrum antipicornaviral agent which ... There was a minimum 7-day washout period between pleconaril doses. ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=105923   www.pubmedcentral.nih.gov - summary ECHO virus infection Enteric cytopathic human orphan (ECHO) viruses are a group of enteroviruses that produce varying symptoms including , ... called pleconaril is undergoing ... http://adam.about.com/encyclopedia/001340trt.htm   adam.about.com - summary ViroPharma - Wikipedia, the free encyclopedia In November 2003, ViroPharma licensed pleconaril to Schering-Plough, who are ... Efficacy and safety of oral pleconaril for treatment of colds due to ... http://en.wikipedia.org/wiki/ViroPharma   en.wikipedia.org - summary Multiple Dose Pharmacokinetics of Pleconaril Tablets in Healthy Adults. BACKGROUND: Pleconaril (P) is an orally active antipicornaviral capsid-function inhibitor. ... pleconaril. Other ID: GWAIDS0029097. UI: 102268729. From Meeting ... http://gateway.nlm.nih.gov/MeetingAbstracts/ma?f=102268729.html   gateway.nlm.nih.gov - summary WHO | Poliomyelitis in the terminal stages Therapeutic recipe of pleconaril in three patients with acute poliovirus ... Treatment of potentially life-threatening enterovirus infections with pleconaril. ... http://www.who.int/bulletin/bulletin_board/82/Polio2/en/   www.who.int - summary VP1 Sequencing of All Human Rhinovirus Serotypes: Insights into Genus ... Pleconaril has been shown in phase 3 human clinical testing to be effective for ... Although the pleconaril susceptibility range of virus serotypes of the HRV-A ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pub...   www.pubmedcentral.nih.gov - summary eMedicine - Coxsackieviruses : Article by Michael Rajnik Coxsackieviruses belong to the family Picornaviridae and the genus Enterovirus, ... Clinical activity of pleconaril in an experimentally induced coxsackievirus A21 ... http://www.emedicine.com/med/topic464.htm   www.emedicine.com - summary Pleconaril for Enteroviral Infections. Pleconaril (ViroPharma, Inc; Exton, PA) inhibits EV and rhinovirus replication ... Studies of pleconaril in other diseases, including viral respiratory infection ... http://gateway.nlm.nih.gov/MeetingAbstracts/ma?f=102246044.html   gateway.nlm.nih.gov - summary Rhinovirus - Wikipedia, the free encyclopedia Activity of pleconaril against enteroviruses. ... Safety and efficacy evaluation of pleconaril for treatment of the common cold. ... http://en.wikipedia.org/wiki/Rhinovirus   en.wikipedia.org - summary Fatal Coxsackievirus A-16 Pneumonitis in Adult | CDC EID Rotbart HA, Webster RD; Pleconaril Treatment Registry Group. Treatment of potentially life-threatening enterovirus infections with pleconaril. ... http://www.cdc.gov/EID/content/13/7/1084.htm   www.cdc.gov - summary VP1 Sequencing of All Human Rhinovirus Serotypes: Insights into Genus ... ... Serotypes: Insights into Genus Phylogeny and Susceptibility to Pleconaril. ... antiviral compounds such as pleconaril bind and inhibit functions associated ... http://gateway.nlm.nih.gov/MeetingAbstracts/ma?f=102265232.html   gateway.nlm.nih.gov - summary In Vitro Antiviral Activity of AG7088, a Potent Inhibitor of Human ... Pirodavir and pleconaril, compounds which inhibit virus capsid attachment and/or ... Pleconaril was included as a negative control. ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=89498   www.pubmedcentral.nih.gov - summary New Cures in the News In December, three new "Miracle Cures" made the news. ... a possibility the medication, called pleconaril, may be effective against other ... http://sleepdisorders.about.com/cs/theflu/a/miracle_cures.htm   sleepdisorders.about.com - summary Pharmacokinetics and Metabolism of 14C-Pleconaril in Healthy Adult Males. Pleconaril (P) is an orally active viral capsid-function inhibitor with ... pleconaril. urine. Other ID: GWAIDS0029100. UI: 102268732. From Meeting Abstracts ... http://gateway.nlm.nih.gov/MeetingAbstracts/ma?f=102268732.html   gateway.nlm.nih.gov - summary Template:Antivirals - Wikipedia, the free encyclopedia purine analogue (guanine) (Aciclovir, Famciclovir, Ganciclovir, Penciclovir, ... Picornavirus (RNA, IV) Pleconaril.? Anti-influenza agents (RNA, V) Arbidol ... http://en.wikipedia.org/wiki/Template:Antivirals   en.wikipedia.org - summary Conservation of Amino Acids in Human Rhinovirus 3C Protease Correlates ... Efficacy and safety of oral pleconaril for treatment of colds due to ... In vitro activity of pleconaril and AG7088 against selected serotypes and ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pub...   www.pubmedcentral.nih.gov - summary Template:Common Cold - Wikipedia, the free encyclopedia Rhinovirus - Coronavirus - Human parainfluenza viruses - Human ... Pleconaril (experimental) Retrieved from "http://en.wikipedia.org/wiki/Template:Common_Cold" ... http://en.wikipedia.org/wiki/Template:Common_Cold   en.wikipedia.org - summary Genome-wide diversity and selective pressure in the human rhinovirus Diversifying pressure in the pleconaril binding site is confined to a single ... Relationship of pleconaril susceptibility and clinical outcomes in treatment of ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1892812   www.pubmedcentral.nih.gov - summary What affects whether or not a drug-resistant virus escapes the cell in ... Proof of concept: are pleconaril (WIN)- sensitive viruses dominant? Drug-sensitive and ... Dominance of pleconaril (WIN)-sensitive. viruses. Virus. RNA. 0 ... http://www3.niaid.nih.gov/news/events/meetings/polio/Kirkegaard.pdf   www3.niaid.nih.gov - summary New Drug May Prevent the Common Cold The drug pleconaril may prevent the common cold and possibly treat it, too. ... Pleconaril users missed up to 45% fewer school or work days, experienced up to ... http://www.webmd.com/allergies/news/20030501/new-drug-may-prevent-common-cold   www.webmd.com - summary Neuraminidase inhibitor - Wikipedia, the free encyclopedia Oseltamivir, zanamivir and peramivir belong to this class. ... Picornavirus (RNA, IV) Pleconaril.? Anti-influenza agents (RNA, V) Arbidol ... http://en.wikipedia.org/wiki/Neuraminidase_inhibitor   en.wikipedia.org - summary In Vitro Resistance Study of Rupintrivir, a Novel Inhibitor of Human ... Pleconaril had progressed through phase III human clinical trials but was later ... Relationship of pleconaril susceptibility and clinical outcome in treatment of ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2167992   www.pubmedcentral.nih.gov - summary List of antiviral drugs - Wikipedia, the free encyclopedia This is a list of antiviral drugs. ... Fixed dose combination (antiretroviral) ... Pleconaril. Podophyllotoxin. Protease inhibitor (pharmacology) [edit] R ... http://en.wikipedia.org/wiki/List_of_antiviral_drugs   en.wikipedia.org - summary Category:Antivirals - Wikipedia, the free encyclopedia Antivirals are drugs that are used to treat infection caused by ... Pleconaril. Podophyllotoxin. Protease inhibitor (pharmacology) R. Ribavirin. T. Taribavirin ... http://en.wikipedia.org/wiki/Category:Antivirals   en.wikipedia.org - summary Potential for Polio Antiviral Drugs Potential for Polio Antiviral Drugs 1. Potential for Polio Antiviral Drugs. Potential for ... Pleconaril. Pleconaril. Capsid. Capsid. Phase. Phase. 1. 1. oral. oral (rhino) (rhino) Compound 1 ... http://www3.niaid.nih.gov/news/events/meetings/polio/Collett.pdf   www3.niaid.nih.gov - summary In Vitro Activity of Expanded-Spectrum Pyridazinyl Oxime Ethers Related ... AG7088 and pleconaril have been or are in clinical trials in the United States ... In vitro activity of pleconaril and AG7088 against selected serotypes and ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=400527   www.pubmedcentral.nih.gov - summary Wonder Drug Coming in for the Cold A new drug is flying through human studies and could be on the market -- to treat ... Data from three trials suggests that pleconaril is no cure, but that it ... http://www.webmd.com/news/20000127/wonder-drug-coming-cold?page=2   www.webmd.com - summary List of drugs: Pj-Pra - Wikipedia, the free encyclopedia pleconaril (INN) Plegine. Plegisol. Plenaxis. Plendil. Pletal. pleuromulin (INN) plicamycin (INN) ... This page was last modified on 28 July 2008, at 19:11. ... http://en.wikipedia.org/wiki/List_of_drugs:_Pj-Pra   en.wikipedia.org - summary Echovirus - Wikipedia, the free encyclopedia The anti-viral drug pleconaril interferes with the binding of the echovirus ... company, ViroPharma Incorporated, ended development of pleconaril in 2004. ... http://en.wikipedia.org/wiki/Echovirus   en.wikipedia.org - summary New Studies May Knock Antiviral Drug Off the Fast Track Two months ago, a lot of people were talking excitedly about the drug pleconaril. ... three new studies may be enough to derail pleconaril from its fast track. ... http://www.webmd.com/news/20000411/new-studies-may-knock-ant...   www.webmd.com - summary Talk:Trifluoromethyl - Wikipedia, the free encyclopedia This article has not yet received a rating on the quality scale. ... Pleconaril. Tipranavir. Mefloquine. Fluminorex. Triflusal. Fluvoxamine. Nilotinib. Sorafenib ... http://en.wikipedia.org/wiki/Talk:Trifluoromethyl   en.wikipedia.org - summary Increased Detections and Severe Neonatal Disease Associated with ... Rotbart HA, Webster AD, Pleconaril Treatment Registry Group. Treatment of potentially life-threatening enterovirus infections with pleconaril. ... http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5720a4.htm   www.cdc.gov - summary Case report: Enteroviruses and sudden deafness The recent development of pleconaril, which may be used as specific therapy for ... Treatment of potentially life-threatening enterovirus infections with pleconaril. ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=155958   www.pubmedcentral.nih.gov - summary Claude H. Nash - Wikipedia, the free encyclopedia Before founding ViroPharma, Nash was Vice President of infectious disease and ... and filed various INDs and an NDA for pleconaril to treat the common cold. ... http://en.wikipedia.org/wiki/Claude_H._Nash   en.wikipedia.org - summary Cure for the Common Cold ... The Elusive Search Although a cure for the common cold has eluded the nation's top scientists for decades, some research shows investigators ... suggest that Pleconaril fights a ... http://www.webmd.com/news/20000127/cure-common-cold-elusive-search   www.webmd.com - summary Mechanism of Action at the Molecular Level of the Antiviral Drug 3(2H ... Among these inhibitors, the drug pleconaril (Viropharma, Exton, Pa.), a novel ... Recently, the new compound pleconaril (VP 63843; Viropharma) has been used for ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=415587   www.pubmedcentral.nih.gov - summary Common cold - Wikipedia, the free encyclopedia ... an antiviral drug, pleconaril, that targets picornaviruses, ... of Pleconaril against ... "Effects of Pleconaril Nasal Spray on Common Cold ... http://en.wikipedia.org/wiki/Common_cold   en.wikipedia.org - summary Rapid and Sensitive Routine Detection of All Members of the Genus ... Treatment of potentially life-threatening enterovirus infections with pleconaril. ... Clinical activity of pleconaril in an experimentally induced coxsackievirus A21 ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=130891   www.pubmedcentral.nih.gov - summary show more 1  2

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