Natamycin ( INN ), also known as pimaricin , is a naturally occurring antifungal agent produced during fermentation by the bacterium Streptomyces natalensis , commonly found in soil. Natamycin has a very low solubility in water, due to the amphiphilic nature of the molecule. more

Natamycin ( INN ), also known as pimaricin , is a naturally occurring antifungal agent produced during fermentation by the bacterium Streptomyces natalensis , commonly found in soil. Natamycin has a very low solubility in water, due to the amphiphilic nature of the molecule. However, natamycin is effective at very low levels. Most Molds have an MIC ( Minimum inhibitory concentration ) of <10ppm. Natamycin is classified as a macrolide polyene antifungal and, as a drug, is used to treat fungal keratitis . It is especially effective against Aspergillus and Fusarium corneal infections. Other common members of the polyene macrolide antifungal family are Amphotericin B , Nystatin , and Filipin . less