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mitomycin c
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what is 'mitomycin c'?
Definition for mitomycin C
The mitomycins are a family of aziridine -containing natural products isolated from Streptomyces lavendulae. One of these compounds, mitomycin C , finds use as a chemotherapeutic agent by virtue of its antitumour antibiotic activity.
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The mitomycins are a family of aziridine -containing natural products isolated from Streptomyces lavendulae. One of these compounds, mitomycin C , finds use as a chemotherapeutic agent by virtue of its antitumour antibiotic activity. It is given intravenously to treat upper gastro-intestinal (e.g. esophageal carcinoma ) and breast cancers , as well as by bladder instillation for superficial bladder tumours . It causes delayed bone marrow toxicity and therefore it is usually administered at 6-weekly intervals. Prolonged use may result in permanent bone-marrow damage. It may also cause lung fibrosis and renal damage .
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diagnoses treated with 'mitomycin c'
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1
diagnosis
anal carcinoma
cancer of the anus
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mitomycin C and anal carcinoma
related procedures when taking 'mitomycin c'
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40
procedures
Abdominal CAT Scan
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mitomycin C and Abdominal CAT Scan
Abdominal MRI
MRI of abdominal contents
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mitomycin C and Abdominal MRI
Abdominoperineal resection
Surgery to remove the anus, rectum, and part of the sigmoid colon through an abdominal incision
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mitomycin C and Abdominoperineal resection
Anal Colposcopy
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mitomycin C and Anal Colposcopy
Anorectal Biopsy
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mitomycin C and Anorectal Biopsy
Anoscopy
test to visualize anus and rectum
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mitomycin C and Anoscopy
BUN
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mitomycin C and BUN
Biopsy
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mitomycin C and Biopsy
Blood, Platelet Count
Platelet Count
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mitomycin C and Blood, Platelet Count
Brachytherapy
Sealed source radiotherapy
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mitomycin C and Brachytherapy
CT anorectal area
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mitomycin C and CT anorectal area
CT scan
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mitomycin C and CT scan
Chemotherapy
Use of chemical substances to treat disease
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mitomycin C and Chemotherapy
Chest X-ray
Radiological technique to image the chest
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mitomycin C and Chest X-ray
Colonoscopy
Colonoscopy
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mitomycin C and Colonoscopy
Complete Blood Count
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mitomycin C and Complete Blood Count
Complete metabolic panel
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mitomycin C and Complete metabolic panel
Cytodiagnosis
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mitomycin C and Cytodiagnosis
Digital rectal exam (DRE)
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mitomycin C and Digital rectal exam (DRE)
Erythrocyte Sedimentation Rate (ESR)
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mitomycin C and Erythrocyte Sedimentation Rate (ESR)
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related medication for 'mitomycin c'
1 - 5 of
5
drugs
5-fluoruracil
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mitomycin C and 5-fluoruracil
cisplatin
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mitomycin C and cisplatin
cisplatin(platinol)
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mitomycin C and cisplatin(platinol)
fluorouracil(adrucil )
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mitomycin C and fluorouracil(adrucil )
mitomycin(mutamycin )
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mitomycin C and mitomycin(mutamycin )
The following are types of physicians relevant for 'mitomycin C'.
related types of physicians 'family practitioner, gastroenterologist, internist, oncologist'
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web search results for 'mitomycin c'?
Results
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- mitomycin C
Mitomycin - Wikipedia, the free encyclopedia
One of these compounds, mitomycin C, finds use as a chemotherapeutic agent by ... Mitomycin C: small, fast and deadly (but very selective) ...
http://en.wikipedia.org/wiki/Mitomycin
en.wikipedia.org
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summary
Mitomycin
Drug details for Mitomycin. ... mitomycin. Mitomycin C, Mutamycin. Mitomycin is an intravenous (IV) medication. ... a simple "A, B, C, D" method to help you ...
http://www.webmd.com/cancer/mitomycin
www.webmd.com
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Mitomycin C for pterygium: long term evaluation
Postoperative instillation of mitomycin C in the treatment of recurrent pterygium. ... Serious complications of topical mitomycin-C after pterygium surgery. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1772401
www.pubmedcentral.nih.gov
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mitomycin C - PubChem Public Chemical Database
PubChem Compound Summary ... mitomycin C - Substance Summary (SID: 7847275) ... MUTAMYCIN (also known as mitomycin and/or mitomycin-C) is an antibiotic isolated ...
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=7847275
pubchem.ncbi.nlm.nih.gov
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Mitomycin - Yahoo! Health
Mitomycin is an antitumor antibiotic used specifically in the treatment of cancer. ... Mitomycin C, Mutamycin. mitomycin. Mitomycin is an intravenous (IV) medication. ...
http://health.yahoo.com/cancer-medications/mitomycin/healthwise--tv6633.html
health.yahoo.com
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mitomycin Information from Drugs.com
mitomycin ... Or browse a complete list of drug names A B C D E F G H I J K L M N O P Q R ... mitomycin B, etc.; mitomycin C is an antineoplastic agent and ...
http://www.drugs.com/dict/mitomycin.html
www.drugs.com
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Definition of mitomycin C - National Cancer Institute Drug Dictionary
Bioreduced mitomycin C generates oxygen radicals, alkylates DNA, and produces ... Preferentially toxic to hypoxic cells, mitomycin C also inhibits RNA and protein ...
http://www.nci.nih.gov/Templates/drugdictionary.aspx?CdrID=42674
www.nci.nih.gov
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Mitomycin
Mitomycin is a chemotherapy drug. It's trade names are Mutamycin, Mitomycin-C and MTC. ... Name: Mitomycin. Trade Name: Mutamycin, Mitomycin-C, MTC ...
http://cancer.about.com/od/chemotherapydrugs/p/Mitomycin.htm...
cancer.about.com
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Serious corneoscleral complications after pterygium excision with ...
The use of topical mitomycin C (MMC) to prevent recurrence after pterygium ... Mitomycin C is an antineoplastic antibiotic agent isolated from the fermentation ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1771048
www.pubmedcentral.nih.gov
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Resistance to mitomycin C requires direct interact...[J Biol Chem. 1999 ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... sensitive to mitomycin C (MMC), FA ...
http://www.ncbi.nlm.nih.gov/pubmed/10567393
www.ncbi.nlm.nih.gov
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Mitomycin facts and comparsions at Drugs.com
... Mitomycin. View complete and up to date Mitomycin information ... Or browse a complete list of drug names A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ...
http://www.drugs.com/cdi/mitomycin.html
www.drugs.com
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Glaucoma
Specific agents, usually mitomycin C, are often used in conjunction with the ... There is a higher risk for cataracts after the use of mitomycin C. ...
http://adam.about.com/reports/000025_8.htm
adam.about.com
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Preoperative topical and intraoperative local mitomycin C adjuvant ...
Topical mitomycin C chemotherapy in the management of ocular surface neoplasias ... Mitomycin C chemotherapy was monitored in conjunction with a clinical oncologist. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1770962
www.pubmedcentral.nih.gov
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MedlinePlus Drug Information: Mitomycin
Mitomycin ... B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9. Mitomycin (mye toe ... Mitomycin-C. Last Revised - 04/01/2003. Last Reviewed - 08/01/2007 ...
http://www.nlm.nih.gov/medlineplus/druginfo/meds/a682415.html
www.nlm.nih.gov
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Mitomycin C in sebaceous gland carcinoma with pagetoid spread
Topical application of mitomycin C, a non-cell cycle specific alkylating agent, ... Mitomycin C was associated with moderate epithelial toxicity which was self ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1772123
www.pubmedcentral.nih.gov
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Mutamycin Drug Information, Professional
Mutamycin Drug Information from Drugs.com. Includes Mutamycin side effects, ... Or browse a complete list of drug names A B C D E F G H I J K L M N O P ... mitomycin-C. ...
http://www.drugs.com/mmx/mutamycin.html
www.drugs.com
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Altered expression of FANCL confers mitomycin C se...[Cancer Biol Ther ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and other life science journals for biomedical ...
http://www.ncbi.nlm.nih.gov/pubmed/17106252
www.ncbi.nlm.nih.gov
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Epiphora as a side effect of topical mitomycin C
Mitomycin C (MMC) is a chemotherapeutic antibiotic isolated from the broth of ... Mitomycin C also causes breakage of single stranded DNA. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1772395
www.pubmedcentral.nih.gov
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eMedicine - Corneal Melt, Postoperative : Article by Arun Verma
Although topical mitomycin-C is effective as an adjunct to pterygium surgery and ... Mitomycin-C and beta radiation must be used with caution, knowing that ...
http://www.emedicine.com/oph/topic65.htm
www.emedicine.com
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Mutamycin Official FDA information, side effects and uses.
Accurate, FDA approved Mutamycin information for healthcare professionals and ... (also known as mitomycin and/or mitomycin-C) is an antibiotic isolated ...
http://www.drugs.com/pro/mutamycin.html
www.drugs.com
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Mitomycin resistance in mammalian cells expressing the bacterial ...
Mitomycin C (MC) and porfiromycin (POR), antibiotics produced by Gram-positive ... Porfiromycin was synthesized from mitomycin C by our laboratory. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=17916
www.pubmedcentral.nih.gov
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A comparison of three chemotherapeutic regimens in...[JAMA. 1985 ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... and mitomycin C versus 5-fluorouracil ...
http://www.ncbi.nlm.nih.gov/pubmed/2579257
www.ncbi.nlm.nih.gov
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Effects of topical mitomycin C on primary trabeculectomies and combined ...
Trabeculectomy with simultaneous topical application of mitomycin-C in refractory glaucoma. ... of brief exposure to mitomycin C on viability and proliferation ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=504626
www.pubmedcentral.nih.gov
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Results of intraoperative mitomycin C application in dacryocystorhinostomy
... the exposure time of mitomycin C in glaucoma filtering surgery. ... The effects of subconjunctival mitomycin-C on glaucoma filtration surgery in rabbits. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1723569
www.pubmedcentral.nih.gov
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Mitomycin consumer information from Drugs.com
Mitomycin patient information. ... Or browse a complete list of drug names A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ...
http://www.drugs.com/cons/Mitomycin.html
www.drugs.com
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ChemIDPlus/HSDB 50-07-7 Toxicity - National Toxicology Program
Mitomycin C ... The frequencies of mitomycin C induced sister chromatid exchanges increased in ... Mitomycin C, initiated between 7 and 10 days after surgery, ...
http://ntp.niehs.nih.gov/index.cfm?objectid=D38B25E1-BDB5-82F8-F1233F176CB3CA8A
ntp.niehs.nih.gov
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Differential toxicity of mitomycin C and porfiromycin to aerobic and ...
Mitomycin C as an adjunct to postoperative radiation therapy in squamous cell ... c reductase and DT-diaphorase in the biotransformation of mitomycin C1. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=40257
www.pubmedcentral.nih.gov
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Long-term effects on corneal keratocytes of mitomy...[J Refract Surg ...
Mitomycin C modulation of corneal wound healing after photorefractive ... Mitomycin C reduces haze formation in rabbits after excimer laser photorefractive ...
http://www.ncbi.nlm.nih.gov/pubmed/18046999?ordinalpos=1&ito...
www.ncbi.nlm.nih.gov
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Mitomycin C as an adjunct in the treatment of localised ocular surface ...
Mitomycin C is an alkylating agent which acts by inhibiting DNA synthesis and ... Topical mitomycin C for extensive, recurrent conjunctival-corneal squamous ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1771954
www.pubmedcentral.nih.gov
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mitomycin
... by Streptomyces caespitosus, variants of which are designated mitomycin A, mitomycin B, etc.; mitomycin C is an antineoplastic agent and a bacteriocide; ...
http://www.drugs.com/dict/mitomycin.html?printable=1
www.drugs.com
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Postoperative adjuvant chemotherapy with mitomycin...[Oncology ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... with mitomycin C, tamoxifen, and ...
http://www.ncbi.nlm.nih.gov/pubmed/9348566?ordinalpos=3&itoo...
www.ncbi.nlm.nih.gov
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Evaluation of the prophylactic use of mitomycin-C to inhibit haze ...
Mitomycin-C is an antimetabolite and antibiotic drug. ... Mitomycin-C has cytotoxic effects through inhibiting DNA synthesis. The logic behind using mitomycin ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=520812
www.pubmedcentral.nih.gov
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Long term results of intraoperative mitomycin C in the treatment of ...
Chayakul V. Prevention of recurrent pterygium by mitomycin-C. Fortschr Ophthalmol. ... complications of topical mitomycin-C after pterygium surgery. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=505450
www.pubmedcentral.nih.gov
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Testing Status: Mitomycin C C04706 - National Toxicology Program
... Testing Status of Agents at NTP >> Testing Status: Mitomycin C C04706 ... Mitomycin C. Print this page Friendly URL. http://ntp.niehs.nih.gov/go/TS-C04706 ...
http://ntp.niehs.nih.gov/index.cfm?objectid=BD360F55-123F-7908-7B8C64C1FDA0739D
ntp.niehs.nih.gov
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Mitomycin C as an adjuvant in resected gastric cancer.
... of their previous experience with mitomycin C at high discontinuous doses in ... Patients were allocated randomly to receive mitomycin C, 20 mg/m2 I.V. direct ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1352924
www.pubmedcentral.nih.gov
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Nucleotide Excision Repair- and Polymerase ?-Mediated Error-Prone ...
Conversely, ICLs induced by mitomycin C (MMC) result in minimum disruption of ... Homology-directed dna repair, mitomycin-c resistance, and chromosome stability ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=151552
www.pubmedcentral.nih.gov
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Lethal effect of mitomycin C on Haemophilus influenzae.
... A. Mutagenic action of mitomycin C on Escherichia coli. Nature. ... Mahler I. Effect of mitomycin C on five excision-repair mutants of Bacillus subtilis. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?&artid=236126
www.pubmedcentral.nih.gov
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Mitomycin lung toxicity. Acute and chronic phases. [Am J Clin Oncol ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE ... induced by mitomycin C is highly ...
http://www.ncbi.nlm.nih.gov/pubmed/9167754?ordinalpos=1&itoo...
www.ncbi.nlm.nih.gov
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Haemolytic-uraemic syndrome complicating long-term mitomycin C and 5 ...
... long-term therapy with mitomycin C and 5-fluorouracil are ... is drawn to the possibility that mitomycin C may sensitise the kidneys to minor mismatches. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=498099
www.pubmedcentral.nih.gov
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Prospective trial of intraoperative mitomycin C in the treatment of ...
CONCLUSION--Intraoperative mitomycin C appears to be an effective and safe ... Ilsar M. The use of low-dose mitomycin C for prevention of recurrent pterygium. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?&artid=505131
www.pubmedcentral.nih.gov
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Definition of folate receptor-targeted vinca alkaloid/mitomycin C ...
folate receptor-targeted vinca alkaloid/mitomycin C EC0225 ... Mitomycin C alkylates DNA, producing DNA cross-links and inhibiting DNA replication. ...
http://www.nci.nih.gov/Templates/drugdictionary.aspx?CdrID=539691
www.nci.nih.gov
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In Vitro Activities of Mitomycin C against Growing and Hypoxic Dormant ...
Mitomycin C showed an MIC (4) of 5 ... Figure 1 A shows that mitomycin C at MIC appears to be ... of the activities of mitomycin C against growing (Fig. 1 A) ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?&artid=90667
www.pubmedcentral.nih.gov
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In Vivo Titration of Mitomycin C Action by Four Escherichia coli ...
Mitomycin C (MMC), a DNA-damaging agent, is a potent inducer of the bacterial ... Mitomycin C (MMC), an antitumor agent isolated from Streptomyces cultures, is ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=95132
www.pubmedcentral.nih.gov
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Genetic Localization and Molecular Characterization of Two Key Genes ...
Mitomycin C (MC) is an antitumor antibiotic derived biosynthetically from 3 ... Henderson I C. Recent advances in the usage of mitomycin. Proceedings of a symposium. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=93634
www.pubmedcentral.nih.gov
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Mitomycin
Mitomycin is rapidly cleared from the serum. C max is 2.4 mcg/mL (after 30 mg IV injection), 1.7 mcg/mL (after 20?mg IV), and ...
http://www.drugs.com/ppa/mitomycin.html?printable=1
www.drugs.com
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INHIBITION OF MICROBIAL GROWTH AND SEPARATION BY d-SERINE, VANCOMYCIN ...
sensitive to mitomycin C and d-serine. ... Bacteriocidal action of mitomycin C. Biochim Biophys Acta. 1961 Oct 14;53:132?149. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=278446
www.pubmedcentral.nih.gov
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Reaction of DNA with chemically or enzymatically activated mitomycin C ...
The antitumor antibiotic mitomycin C is shown to form a covalent complex with ... c reductase and DT-diaphorase in the biotransformation of mitomycin C1. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=386577
www.pubmedcentral.nih.gov
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Evaluation of planned treatment breaks during radi...[Int J Radiat ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... flourouracil + mitomycin-C with a ...
http://www.ncbi.nlm.nih.gov/pubmed/18472363
www.ncbi.nlm.nih.gov
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eMedicine - Glaucoma and Penetrating Keratoplasty : Article by Ramesh S ...
Mitomycin-C trabeculectomy is the safest operation both in terms of IOP control ... Literature favors a combined mitomycin-C trabeculectomy with corneal graft ...
http://www.emedicine.com/oph/topic760.htm
www.emedicine.com
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Effects of Mitomycin C on Macromolecular Synthesis in Escherichia coli
Effect of mitomycin C on the synthesis of induced bita-galactosidase in E. coli. ... Bacteriocidal action of mitomycin C. Biochim Biophys Acta. 1961 Oct 14;53: ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=276494
www.pubmedcentral.nih.gov
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