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melarsoprol
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what is 'melarsoprol'?
Definition for melarsoprol
Melarsoprol ( INN ) is a medicinal drug used in the treatment of Human African trypanosomiasis . [ 1 ] It is also sold under the trade names ?Mel B? and ?Melarsen Oxide-BAL.?
Melarsoprol is also used in the treatment of Chagas disease [ citation needed ] .
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Melarsoprol ( INN ) is a medicinal drug used in the treatment of Human African trypanosomiasis . [ 1 ] It is also sold under the trade names ?Mel B? and ?Melarsen Oxide-BAL.?
Melarsoprol is also used in the treatment of Chagas disease [ citation needed ] .
Being a toxic organic compound of arsenic , melarsoprol is a highly dangerous treatment which is only administered by injection under the supervision of a physician.
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diagnoses treated with 'melarsoprol'
1 - 1 of
1
diagnosis
African Trypanosomiasis
sleeping sickness in Africa
web search for:
melarsoprol and African Trypanosomiasis
related procedures when taking 'melarsoprol'
1 - 5 of
28
procedures
Blood, Platelet Count
Platelet Count
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melarsoprol and Blood, Platelet Count
Bone Marrow Aspiration
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melarsoprol and Bone Marrow Aspiration
Brain MRI
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melarsoprol and Brain MRI
CT brain
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melarsoprol and CT brain
CT scan
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melarsoprol and CT scan
Cerebrospinal Fluid ELISA
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melarsoprol and Cerebrospinal Fluid ELISA
Cerebrospinal Fluid PCR
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melarsoprol and Cerebrospinal Fluid PCR
Cerebrospinal Fluid analysis
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melarsoprol and Cerebrospinal Fluid analysis
Cerebrospinal Fluid immunoglobulin M
web search for:
melarsoprol and Cerebrospinal Fluid immunoglobulin M
Cerebrospinal Fluid immunoglobulins
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melarsoprol and Cerebrospinal Fluid immunoglobulins
Complete Blood Count
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melarsoprol and Complete Blood Count
Drainage of Lymph Node
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melarsoprol and Drainage of Lymph Node
Erythrocyte Sedimentation Rate (ESR)
web search for:
melarsoprol and Erythrocyte Sedimentation Rate (ESR)
Giemsa staining
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melarsoprol and Giemsa staining
Lumbar Puncture
web search for:
melarsoprol and Lumbar Puncture
Serum Albumin
type of protein in human plasma
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melarsoprol and Serum Albumin
Ultrasound lymph node
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melarsoprol and Ultrasound lymph node
aspiration chancre
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melarsoprol and aspiration chancre
aspiration lymph node
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melarsoprol and aspiration lymph node
buffy coat analysis
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melarsoprol and buffy coat analysis
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related medication for 'melarsoprol'
1 - 3 of
3
drugs
effornithine
web search for:
melarsoprol and effornithine
pentamidine isethionate
web search for:
melarsoprol and pentamidine isethionate
suramin
web search for:
melarsoprol and suramin
The following are types of physicians relevant for 'melarsoprol'.
related types of physicians 'family practitioner, infectious disease specialist, internist'
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web search results for 'melarsoprol'?
Results
1 - 50
- melarsoprol
Melarsoprol - Wikipedia, the free encyclopedia
Melarsoprol (INN) is a medicinal drug used in the treatment of Human African ... Retrieved from "http://en.wikipedia.org/wiki/Melarsoprol" ...
http://en.wikipedia.org/wiki/Melarsoprol
en.wikipedia.org
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summary
Melarsoprol Drug Information, Professional
Melarsoprol Drug Information from Drugs.com. Includes Melarsoprol side effects, interactions and indications. ... the trypanosome, melarsoprol inactivates the ...
http://www.drugs.com/MMX/Melarsoprol.html
www.drugs.com
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Relapses after Melarsoprol Treatment of Trypanosomiasis | CDC EID
Trypanosomiasis Relapse after Melarsoprol Therapy, Democratic Republic of Congo, 1982?2001 ... Melarsoprol was used throughout the study period for most adult ...
http://www.cdc.gov/ncidod/EID/vol11no06/05-0036.htm
www.cdc.gov
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summary
Melarsoprol versus eflornithine for treating late-stage Gambian ...
melarsoprol regimen between April 2001 and April 2005. ... course melarsoprol. ... Conclusion The effectiveness of melarsoprol treatment appears to have diminished. ...
http://www.who.int/bulletin/volumes/84/10/06-031955.pdf
www.who.int
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summary
Equivalence trial of melarsoprol and nifurtimox mo...[J Infect Dis ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and other life science journals for biomedical ...
http://www.ncbi.nlm.nih.gov/pubmed/17205469
www.ncbi.nlm.nih.gov
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summary
MELARSOPROL - PubChem Public Chemical Database
PubChem Compound Summary ... MELARSOPROL - Compound Summary (CID: 10311) Arsenical used in trypanosomiases. ... (Total:1) Melarsoprol. Pharmacological Action ...
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=10311
pubchem.ncbi.nlm.nih.gov
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summary
Three Drug Combinations for Late-Stage Trypanosoma brucei gambiense ...
Since 1949, melarsoprol has been the most commonly used stage 2 treatment. ... Better tolerated than melarsoprol, its toxic effects?mainly seizures, ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1687208
www.pubmedcentral.nih.gov
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summary
Melarsoprol consumer information from Drugs.com
Melarsoprol patient information. ... Melarsoprol is to be administered only in the hospital by or ... For melarsoprol, the following should be considered: ...
http://www.drugs.com/cons/melarsoprol.html
www.drugs.com
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Melarsoprol Failure Rates, Congo | CDC EID
Melarsoprol was used on a massive and unprecedented scale in Equateur Nord ... Table 1. Melarsoprol relapse rates in second-stage human African trypanosomiasis ...
http://www.cdc.gov/eid/content/14/6/966.htm
www.cdc.gov
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Melarsoprol - Wikipedia, la enciclopedia libre
El melarsoprol también conocido como Mel B, es el producto de la condensación ... Obtenido de "http://es.wikipedia.org/wiki/Melarsoprol" ...
http://es.wikipedia.org/wiki/Melarsoprol
es.wikipedia.org
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Talk:Melarsoprol - Wikipedia, the free encyclopedia
Melarsoprol is part of WikiProject Pharmacology, a project to improve all ... Retrieved from "http://en.wikipedia.org/wiki/Talk:Melarsoprol" ...
http://en.wikipedia.org/wiki/Talk:Melarsoprol
en.wikipedia.org
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Report of the Sixth Steering Committee Meeting 28-29 May 2002
Melarsoprol ... and where high melarsoprol resistance is prevalent. ... It should continue to be used to respond to treatment failure with melarsoprol. ...
http://whqlibdoc.who.int/hq/2002/WHO_CDS_CSR_EPH_2002.20.pdf
whqlibdoc.who.int
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summary
Efficacy of new, concise schedule for melarsoprol in treatment of ...
... adverse reactions to the first-line drug, melarsoprol. ... Despite these problems, melarsoprol is likely to remain the drug of choice for the next decade. ...
http://www.ncbi.nlm.nih.gov/pubmed/10791526
www.ncbi.nlm.nih.gov
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summary
MANUFACTURERS OF DRUGS USED TO TREAT PARASITIC INFECTIONS
... fail to respond to melarsoprol (MP Barrett, Lancet 1999; 353: ... effective than standard-dose melarsoprol alone (S Bisser et al, J Infect Dis 2007; 195:322) ...
http://www.dpd.cdc.gov/dpdx/HTML/PDF_Files/MedLetter/Trypanosomiasis.pdf
www.dpd.cdc.gov
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summary
WHO | Melarsoprol versus eflornithine for treating late-stage Gambian ...
To compare the effectiveness of melarsoprol and eflornithine in treating late ... The effectiveness of melarsoprol treatment appears to have diminished. ...
http://www.who.int/bulletin/volumes/84/10/06-031955ab/en/index.html
www.who.int
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summary
Mechanisms of Arsenical and Diamidine Uptake and Resistance in ...
In T. brucei, the uptake of melarsoprol as well as diamidines is thought to be ... Melarsoprol treatment failures have reached alarming levels in several foci (4) ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=219364
www.pubmedcentral.nih.gov
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summary
eMedicine - African Trypanosomiasis (Sleeping Sickness) : Article by ...
Human African trypanosomiasis (HAT), or sleeping sickness, is an illness endemic ... In addition, melarsoprol resistance has become a concern in the Congo and Uganda; ...
http://www.emedicine.com/med/topic2140.htm
www.emedicine.com
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summary
Trypanosomiasis Relapse after Melarsoprol Therapy, Democratic Republic ...
treated with melarsoprol during this period in Nioki, ... drug to melarsoprol for patients in ... December 2001, a trial of 3 regimens of melarsoprol took ...
http://www.cdc.gov/ncidod/EID/vol11no06/pdfs/05-0036.pdf
www.cdc.gov
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summary
Sleeping sickness - Wikipedia, the free encyclopedia
Equivalence trial of melarsoprol and nifurtimox monotherapy and combination ... Eflornithine is safer than melarsoprol for the treatment of second-stage ...
http://en.wikipedia.org/wiki/African_trypanosomiasis
en.wikipedia.org
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summary
The phenomenon of treatment failures in Human African Trypanosomiasis.
The in vitro melarsoprol sensitivities for populations from relapsing and from ... Melarsoprol concentrations in the plasma and cerebrospinal fluid of patients 24 ...
http://www.ncbi.nlm.nih.gov/pubmed/11703845
www.ncbi.nlm.nih.gov
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summary
CRISP - Computer Retrieval of Information on Scientific Projects ...
... mediate the translocation of melarsoprol and pentamidine, two anti-trypanosomal ... and oocytes, to determine whether either transporter recognizes melarsoprol ...
http://crisp.cit.nih.gov/crisp/CRISP_LIB.getdoc?textkey=6632...
crisp.cit.nih.gov
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summary
The Melaminophenyl Arsenicals Melarsoprol and Melarsen Oxide Interfere ...
Melarsoprol is taken up by cells in a thiamine- and car1p-dependent manner but ... The melaminophenyl arsenical melarsoprol (Mel B) is the main drug used against ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=514754
www.pubmedcentral.nih.gov
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summary
Control of human African trypanosomiasis in the Quic¸ama focus, Angola
3.5% in patients treated with melarsoprol. ... encephalopathy among the melarsoprol-treated patients was 1.7 ... melarsoprol treatment was preceded by a single ...
http://www.who.int/bulletin/archives/en/80(9)738.pdf
www.who.int
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summary
High Failure Rates of Melarsoprol for Sleeping Sickness, Democratic ...
trypanosomiasis patients treated with melarsoprol in 2001 ... the meningoencephalitic or second stage, melarsoprol, an ... now melarsoprol resistance could ...
http://www.cdc.gov/eid/content/14/6/pdfs/966.pdf
www.cdc.gov
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Naganin
... involving the CNS, the primary agent is the toxic arsenical compound melarsoprol. ... as a preliminary agent prior to starting melarsoprol therapy in order to ...
http://www.drugs.com/mmx/naganin.html?printable=1
www.drugs.com
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summary
www.emro.who.int/ApplicationsCall12.doc
Evaluation of short treament duration with pentamidine, suramin and melarsoprol. Investigation of the existence of melarsoprol resistance. ...
http://www.emro.who.int/ApplicationsCall12.doc
www.emro.who.int
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summary
Research Short-course eflornithine in Gambian trypanosomiasis: a ...
trypanosomiasis has been melarsoprol, an arsenical, ... melarsoprol, but less frequent because eflornithine is ... treated with melarsoprol, a drug which kills ...
http://whqlibdoc.who.int/bulletin/2000/Number%2011/78(11)1284-1295.pdf
whqlibdoc.who.int
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summary
Advances in sleeping sickness therapy.
... agents for gambiense sleeping sickness, including melarsoprol-refractory disease. ... effective late-stage drugs (melarsoprol, nifurtimox and DFMO), that ...
http://www.ncbi.nlm.nih.gov/pubmed/1417168
www.ncbi.nlm.nih.gov
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Nifurtimox - Wikipedia, the free encyclopedia
... awaited comparing melarsoprol/nifurtimox against melarsoprol alone for African ... Equivalence Trial of Melarsoprol and Nifurtimox Monotherapy and Combination ...
http://en.wikipedia.org/wiki/Nifurtimox
en.wikipedia.org
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WHO | Treatment
... of suramin (1920), pentamidine (1940) and melarsoprol (1949), a ... Melarsoprol versus eflornithine for treating late-stage Gambian trypanosomiasis ...
http://www.who.int/trypanosomiasis_african/research/treatment/en/index.html
www.who.int
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summary
Nifurtimox plus Eflornithine for Late-Stage Sleeping Sickness in Uganda ...
The historical mainstay, melarsoprol, is highly toxic and inefficacious in some ... Eflornithine is safer than melarsoprol for the treatment of second-stage ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2100371
www.pubmedcentral.nih.gov
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summary
Efficacy of 10-day melarsoprol schedule 2 years after treatment for ...
Efficacy of 10-day melarsoprol schedule 2 years after treatment for late-stage ... reported that a new short treatment schedule of melarsoprol was not worse than ...
http://www.ncbi.nlm.nih.gov/pubmed/15337407
www.ncbi.nlm.nih.gov
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World Health Organization
Melarsoprol treatment failures have been reported in ... The existence of intrinsically resistant parasites to melarsoprol yet ...
http://whqlibdoc.who.int/hq/1999/WHO_CDS_CSR_EDC_99.5.pdf
whqlibdoc.who.int
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summary
Co-infection of vervet monkeys with trypanosomes and SIV leads to rapid ...
... with a curative dose of melarsoprol, 3 with a subcurative dose of ... In addition, 2 melarsoprol-treated monkeys showed relapse of parasitaemia within ...
http://gateway.nlm.nih.gov/MeetingAbstracts/ma?f=102226781.html
gateway.nlm.nih.gov
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summary
Cost-effectiveness analysis of alternative treatme...[Health Econ. 1995 ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... Melarsoprol versus eflornithine for ...
http://www.ncbi.nlm.nih.gov/pubmed/8528430
www.ncbi.nlm.nih.gov
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summary
www.emro.who.int/applicationscall12ar.doc
????? ?????? ???? ????? ??????pentamidine, suramin and melarsoprol. ????????? ?? ???? ?????? ????? melarsoprol ... ?????? ????????? ?????? ????? melarsoprol. ...
http://www.emro.who.int/applicationscall12ar.doc
www.emro.who.int
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Eflornithine - Wikipedia, the free encyclopedia
... resumed production of eflornithine, melarsoprol and pentamidine in sufficient ... Arsenic compounds. Melarsoprol. Other agents. Pentamidine · Suramin ...
http://en.wikipedia.org/wiki/Eflornithine
en.wikipedia.org
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summary
Editorial Gambiense sleeping sickness: re-emerging and soon untreatable?
therapy for melarsoprol-refractory sleeping. sickness, and eflornithine was first tried for ... The availability of melarsoprol and. of the first-stage drugs ...
http://www.who.int/bulletin/archives/78(11)1283.pdf
www.who.int
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summary
Randomized controlled trial of three regimens of m...[Trans R Soc Trop ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from ... after melarsoprol therapy, Democratic ...
http://www.ncbi.nlm.nih.gov/pubmed/16483622
www.ncbi.nlm.nih.gov
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summary
Contribution of Dithiol Ligands to In Vitro and In Vivo Trypanocidal ...
... little improvement over melarsoprol (1), but melarsamine ... Friedheim E A H, Distefano D. Melarsoprol in the treatment of African sleeping sickness. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=101586
www.pubmedcentral.nih.gov
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Antiparasitic - Wikipedia, the free encyclopedia
Melarsoprol (for treatment of sleeping sickness caused by Trypanosoma brucei) [edit] See also ... Arsenic compounds. Melarsoprol. Other agents. Pentamidine ...
http://en.wikipedia.org/wiki/Antiparasitic
en.wikipedia.org
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African Trypanosomiasis
treatment received ? melarsoprol (for late-stage disease) ... growth and performance of the melarsoprol treated ... melarsoprol causes reactive encephalopathy in 5-10 ...
http://www.who.int/tdr/publications/publications/pdf/pr13/tryps.pdf
www.who.int
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summary
Three drug combinations for late-stage Trypanosoma...[PLoS Clin Trials ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... trial of melarsoprol and nifurtimox ...
http://www.ncbi.nlm.nih.gov/pubmed/17160135
www.ncbi.nlm.nih.gov
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summary
CDC - African Trypanosomiasis in Travelers Returning to the United Kingdom
CNS involvement is treated with melarsoprol in 12 escalating doses over 4 weeks ... A, Smith T, Blum J, Brun R. Efficacy of new, concise schedule for melarsoprol ...
http://www.cdc.gov/ncidod/eid/vol8no1/01-0130.htm
www.cdc.gov
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Template:Agents against leishmaniasis and trypanosomiasis - Wikipedia ...
Antiparasitics ? Antiprotozoals: Agents against ... Arsenic compounds. Melarsoprol. Other agents. Pentamidine · Suramin · Eflornithine · Miltefosine ...
http://en.wikipedia.org/wiki/Template:Agents_against_leishma...
en.wikipedia.org
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Algorithms for Human African Trypanosomiasis | CDC EID
... occurrence and outcome during melarsoprol treatment of human African trypanosomiasis. ... for treatment failure after melarsoprol for Trypanosoma brucei gambiense ...
http://www.cdc.gov/eid/content/13/10/1484.htm
www.cdc.gov
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summary
Sleeping sickness?a growing problem?
... way to avoid using existing potent drugs (melarsoprol) or drugs that are very ... donation of drugs?pentamidine, melarsoprol, eflornithine (Sanofi-Aventis), and ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pub...
www.pubmedcentral.nih.gov
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summary
Comparison of nanosuspensions and hydroxypropyl-be...[Eur J Pharm ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 ... The organic solution of melarsoprol (Mel B, 0.039mmol/kg), injected ...
http://www.ncbi.nlm.nih.gov/pubmed/18582565?ordinalpos=1&ito...
www.ncbi.nlm.nih.gov
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summary
Antiprotozoal agent - Wikipedia, the free encyclopedia
Melarsoprol. Metronidazole. Ornidazole. Paromomycin sulfate. Pentamidine. Pyrimethamine ... Gastrointestinal tract/metabolism (A) ...
http://en.wikipedia.org/wiki/Antiprotozoal_agent
en.wikipedia.org
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Final Report No.8 - African trypanosomiasis: eflornithine treatment ...
... melarsoprol but who had relapsed) a 7-day course of eflornithine was as ... with melarsoprol and then relapsed; and new cases, patients who had not been ...
http://www.who.int/tdr/research/finalreps/no8.htm
www.who.int
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