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lomustine (ccnu)
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what is 'lomustine (ccnu)'?
Definition for lomustine (CCNU)
Lomustine (or "CCNU")(Marketed under the name CeeNU in US) is an alkylating nitrosourea compound used in chemotherapy . It is in the same family as streptozotocin . This is a highly lipid soluble drug, and thus crosses the blood brain barrier.
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Lomustine (or "CCNU")(Marketed under the name CeeNU in US) is an alkylating nitrosourea compound used in chemotherapy . It is in the same family as streptozotocin . This is a highly lipid soluble drug, and thus crosses the blood brain barrier. This property makes it ideal for treating brain tumors, and is its primary use. Lomustine has a long time to nadir (the time when white blood cells reach their lowest number).
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diagnoses treated with 'lomustine (ccnu)'
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3
diagnosis
intracranial tumor
brain tumor
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lomustine (CCNU) and intracranial tumor
ganglioglioma
benign brain tumor
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lomustine (CCNU) and ganglioglioma
Mediterranean spotted fever
rare rickettsial disease
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lomustine (CCNU) and Mediterranean spotted fever
related procedures when taking 'lomustine (ccnu)'
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21
procedures
Biopsy
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lomustine (CCNU) and Biopsy
Biopsy bone marrow
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lomustine (CCNU) and Biopsy bone marrow
Bone Marrow Aspiration
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lomustine (CCNU) and Bone Marrow Aspiration
Brachytherapy
Sealed source radiotherapy
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lomustine (CCNU) and Brachytherapy
Brain MRI
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lomustine (CCNU) and Brain MRI
CT brain
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lomustine (CCNU) and CT brain
CT scan
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lomustine (CCNU) and CT scan
Cerebrospinal Fluid Shunt
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lomustine (CCNU) and Cerebrospinal Fluid Shunt
Complete metabolic panel
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lomustine (CCNU) and Complete metabolic panel
Craniotomy
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lomustine (CCNU) and Craniotomy
External Beam Radiation
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lomustine (CCNU) and External Beam Radiation
Lumbar Puncture
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lomustine (CCNU) and Lumbar Puncture
Open biopsy
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lomustine (CCNU) and Open biopsy
Positron emission tomography (PET)
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lomustine (CCNU) and Positron emission tomography (PET)
Resection
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lomustine (CCNU) and Resection
Stereotactic brain biopsy
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lomustine (CCNU) and Stereotactic brain biopsy
Ventriculoperitoneal shunt
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lomustine (CCNU) and Ventriculoperitoneal shunt
cranial irradiation
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lomustine (CCNU) and cranial irradiation
craniospinal radiation
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lomustine (CCNU) and craniospinal radiation
serum electrolytes
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lomustine (CCNU) and serum electrolytes
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related medication for 'lomustine (ccnu)'
1 - 5 of
9
drugs
carboplatin
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lomustine (CCNU) and carboplatin
cisplatin
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lomustine (CCNU) and cisplatin
cyclophosphamide
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lomustine (CCNU) and cyclophosphamide
etoposide
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lomustine (CCNU) and etoposide
methotrexate
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lomustine (CCNU) and methotrexate
temozolomide
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lomustine (CCNU) and temozolomide
thiotepa
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lomustine (CCNU) and thiotepa
vincristine
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lomustine (CCNU) and vincristine
carmustine (bcnu)
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lomustine (CCNU) and carmustine (bcnu)
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The following are types of physicians relevant for 'lomustine (CCNU)'.
related types of physicians 'family practitioner, internist, neurologist, neuroradiology specialist, neurosurgeon, oncologist'
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web search results for 'lomustine (ccnu)'?
Results
1 - 50
- lomustine (CCNU)
Lomustine - Wikipedia, the free encyclopedia
Lomustine (or "CCNU")(Marketed under the name CeeNU in US) is an alkylating ... Retrieved from "http://en.wikipedia.org/wiki/Lomustine" ...
http://en.wikipedia.org/wiki/Lomustine
en.wikipedia.org
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summary
Lomustine (CCNU)
Lomustine (CCNU) is usually taken as a single dose only once every 6 weeks. ... Lomustine (CCNU) often decreases bone marrow function and lowers the number of ...
http://www.drugs.com/cdi/lomustine-ccnu.html?printable=1
www.drugs.com
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summary
CCNU (Lomustine)
CCNU (lomustine) is a yellow powder, stable in pure form and in solution at ... Synonyms: CCNU; CeeNU; N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea; lomustine; NCI ...
http://dohs.ors.od.nih.gov/pdf/CCNU%20REVISED.pdf
dohs.ors.od.nih.gov
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summary
Reappraisal of the use of procarbazine in the treatment of lymphomas ...
... commonly combined in the PCV (procarbazine, lomustine [CCNU], and vincristine) ... Randomized trial of procarbazine, lomustine, and vincristine in the adjuvant ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1936303
www.pubmedcentral.nih.gov
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summary
lomustine - PubChem Public Chemical Database
PubChem Compound Summary ... lomustine - Compound Summary (CID: 3950) ... CeeNU (lomustine) (CCNU) is one of the nitrosoureas used in the treatment of ...
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=3950
pubchem.ncbi.nlm.nih.gov
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summary
Adding lomustine to idarubicin and cytarabine for ...[Haematologica ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE ... drugs plus lomustine (CCNU), 200 mg\m ...
http://www.ncbi.nlm.nih.gov/pubmed/18024370
www.ncbi.nlm.nih.gov
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summary
lomustine
... long chain fatty acid. lomustine. Used for: CCNU (cyclohexylchloroethylnitrosourea) Used for: ... See for: CCNU. See for: chloroethylnitrosourea. Broader Terms: ...
http://crisp.cit.nih.gov/Thesaurus/00004712.htm
crisp.cit.nih.gov
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summary
Lomustine (CCNU) facts and comparsions at Drugs.com
All about Lomustine (CCNU). View complete and up to date Lomustine (CCNU) information - part of the Drugs.com trusted medication database.
http://www.drugs.com/cdi/lomustine-ccnu.html
www.drugs.com
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summary
ChemIDPlus/HSDB 13010-47-4 Toxicity - National Toxicology Program
... and dose-limiting adverse effect of lomustine is delayed hematologic toxicity. ... CCNU concentration was selected to approximate the maximal increase in sister ...
http://ntp.niehs.nih.gov/index.cfm?objectid=E87D34B3-BDB5-82F8-F1C376E4A3F72728
ntp.niehs.nih.gov
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summary
CCNU - Wikipedia, the free encyclopedia
CCNU. From Wikipedia, the free encyclopedia. Jump to: navigation, search ... Lomustine, a ... en.wikipedia.org/wiki/CCNU" Categories: Disambiguation pages ...
http://en.wikipedia.org/wiki/CCNU
en.wikipedia.org
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summary
semustine - PubChem Public Chemical Database
PubChem Compound Summary ... 4-Methyl derivative of LOMUSTINE; (CCNU) ... Methyl-CCNU. 1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea. C07640. 13909-09-6 ...
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=9842
pubchem.ncbi.nlm.nih.gov
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summary
MedlinePlus Drug Information: Lomustine
Lomustine ... Lomustine may harm the fetus. ... Other names Return to top. CCNU. Last Revised - 04/01/2003. Last Reviewed - 08/01/2007 ...
http://www.nlm.nih.gov/medlineplus/druginfo/meds/a682207.html
www.nlm.nih.gov
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summary
High-dose chemotherapy with stem cell rescue as initial therapy for ...
... with intensive procarbazine, CCNU (lomustine), and vincristine (PCV) followed by ... every six weeks as follows: lomustine (CCNU), 130 mg/m2 p.o., was ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1871935
www.pubmedcentral.nih.gov
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summary
Late Effects of Treatment for Childhood Cancer
Central Nervous System Neurocognitive Neurocognitive late effects most commonly follow treatment of malignancies that ... lomustine (CCNU), carmustine ...
http://www.webmd.com/cancer/tc/late-effects-of-treatment-for...
www.webmd.com
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summary
Lomustine (CCNU) Side Effects | Drugs.com
Comprehensive and accurate Lomustine (CCNU) side effects information for consumers and healthcare professionals. ... effects for Lomustine (CCNU) may not be ...
http://www.drugs.com/sfx/lomustine-ccnu-side-effects.html
www.drugs.com
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summary
Definition of lomustine - National Cancer Institute Drug Dictionary
Lomustine alkylates and crosslinks DNA, thereby inhibiting DNA and RNA synthesis. ... CCNU. Code names: RB-1509. WR-139017. Chemical structure names: ...
http://www.nci.nih.gov/Templates/drugdictionary.aspx?CdrID=43065
www.nci.nih.gov
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summary
Combination of CCNU and DTIC chemotherapy for trea...[J Vet Intern Med ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE ... Lomustine (CCNU) for the treatment of ...
http://www.ncbi.nlm.nih.gov/pubmed/18289305?ordinalpos=1&ito...
www.ncbi.nlm.nih.gov
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summary
Melanoma
An in-depth report on the causes, diagnosis, treatment, and prevention ... Nitrosoureas, which include carmustine (BCNU) and lomustine (CCNU) are often used. ...
http://adam.about.com/reports/000032_6.htm
adam.about.com
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summary
Table 1. Database for drugs analyzed in this study. Mechanism of ...
... 366140 6.56 0.29 15 43.4 A6 Lomustine (CCNU) 79037 4.35 0.31 56 38.9 ALK A7 ... ALK A6 C2 Ca 79037 Lomustine (CCNU) Ds Fluorouracil (5FU) 19893 4.63 0.73 1149 ...
http://discover.nci.nih.gov/nature2000/Figures/table1.txt
discover.nci.nih.gov
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summary
CRISP - Computer Retrieval of Information on Scientific Projects ...
... regimen, consisting of lomustine (CCNU), etoposide (VP-16) cyclophosphamide ... etoposide, human herpesvirus 8, lomustine, oral administration, procarbazine ...
http://crisp.cit.nih.gov/crisp/CRISP_LIB.getdoc?textkey=6661...
crisp.cit.nih.gov
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summary
Nitrosourea - Wikipedia, the free encyclopedia
Some nitrosoureas (e.g. Lomustine) have been associated with the development of ... Lomustine (CCNU)-induced pulmonary fibrosis.". Tumori 72 (1): 95-8. PMID 3952821. ...
http://en.wikipedia.org/wiki/Nitrosourea
en.wikipedia.org
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summary
MedlinePlus Drug Information: Drugs beginning with Ca
CCNU see Lomustine. CDDP see Cisplatin. CeclorŽ see Cefaclor. CeclorŽ PulvulesŽ see Cefaclor ... see Lomustine. CeeNUŽDose Pack see Lomustine. Cefaclor ...
http://www.nlm.nih.gov/medlineplus/druginfo/drug_Ca.html
www.nlm.nih.gov
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summary
Lomustine Side Effects | Drugs.com
Comprehensive and accurate Lomustine side effects information for ... most COMMON side effects persist or become bothersome when using Lomustine (CCNU) ...
http://www.drugs.com/sfx/lomustine-side-effects.html
www.drugs.com
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summary
eMedicine - Oligodendroglioma : Article by ABM Salah Uddin
Oligodendrogliomas (ODs) are primary glial brain tumors that are divided into ... Most used procarbazine, lomustine (CCNU), and vincristine, a combination ...
http://www.emedicine.com/neuro/topic281.htm
www.emedicine.com
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summary
4. INTRODUCTION 4.1. Investigational Plan
Lomustine (CCNU) 270. 35(13) 9-17. Tauromustine (TCNU) 42. 7(17) 6-31. Fotemustine. 153 ... Me-CCNU, methyl-CCNU; PR, partial response; TAM, tamoxifen; VCR, ...
http://www4.od.nih.gov/oba/rac/abstracts/234_s.pdf
www4.od.nih.gov
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summary
Methyl-CCNU (Semustine)
Very little has been published on cis-Me-CCNU,but it appears that ... Clinical pharmacokinetics of of oral CCNU (lomustine). Cancer Chemother Pharmacol 14:125-131. ...
http://dohs.ors.od.nih.gov/pdf/Methyl-CCNU%20_Semustine_%20REVISED.pdf
dohs.ors.od.nih.gov
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summary
Lomustine for treatment of mast cell tumors in cat...[J Am Vet Med ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE ... tumors with CCNU (lomustine). [J Vet ...
http://www.ncbi.nlm.nih.gov/pubmed/18412534?ordinalpos=1&ito...
www.ncbi.nlm.nih.gov
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summary
lomustine
Information for lomustine on Drugs.com. May include images, interactions ... Lomustine (CCNU) Lomustine (CCNU) is used for: Treating certain types of cancer. ...
http://www.drugs.com/search.php?searchterm=lomustine&is_main_search=1
www.drugs.com
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summary
Correlation distance (1-r) Euclidian distance on correlation coefficient
A6: Lomustine (CCNU) -A7: Fluorodopan -A6: Semustine ... A6: Lomustine (CCNU) -A7: Spiromustine -A7: Fluorodopan -Uk: Inosine-glycodial. -TU: Maytansine ...
http://discover.nci.nih.gov/nature2000/paper/fig3.pdf
discover.nci.nih.gov
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summary
Brain and Spinal Cord Tumors
A comprehensive overview about the many varieties of brain and spinal cord ... known by the initials BCNU (sometimes called carmustine) and CCNU (or lomustine) ...
http://www.webmd.com/cancer/brain-cancer/brain-spinal-cord-tumors?page=8
www.webmd.com
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summary
Treatment-related myelodysplasia/AML in a patient with a history of ...
... in Fig. 1. We believe that procarbazine and lomustine contributed little to the ... used are as follows: CCNU, lomustine: 1-(2-chloroethyl)-3-cyclohexyl-1 ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1871950
www.pubmedcentral.nih.gov
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summary
Lomustine Drug Information, Professional
Lomustine Drug Information from Drugs.com. Includes Lomustine side effects, interactions and ... CCNU. ... Lomustine (and/or its metabolites) interferes with the function of ...
http://www.drugs.com/MMX/Lomustine.html
www.drugs.com
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summary
Practical guidelines for the treatment of malignan...[West J Med. 1998 ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... and lomustine (CCNU) and vincristine, ...
http://www.ncbi.nlm.nih.gov/pubmed/9499745
www.ncbi.nlm.nih.gov
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summary
Procarbazine - Wikipedia, the free encyclopedia
... dosed as PCV when combined with Lomustine (often called CCNU) and Vincristine. ... (Carmustine, Fotemustine, Lomustine, Nimustine, Prednimustine, Ranimustine, ...
http://en.wikipedia.org/wiki/Procarbazine
en.wikipedia.org
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summary
methyl-CCNU
Close Print this page. methyl-CCNU. Pronunciation: meth?il ... antineoplastic agent resembling carmustine (BCNU) and lomustine (CCNU). Synonym(s): semustine ...
http://www.drugs.com/dict/methyl-ccnu.html?printable=1
www.drugs.com
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summary
eMedicine - Late Effects of Childhood Cancer and Treatment : Article by ...
Survival rates for almost all types of childhood cancer have improved ... RT, bleomycin, or BCNU or lomustine (CCNU) should undergo PFTs at baseline, then ...
http://www.emedicine.com/ped/topic2591.htm
www.emedicine.com
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summary
DOHS | Material Safety Data Sheets
CCNU (Lomustine) Chlorambucil. Chloramphenical ... Methyl-CCNU (Semustine) Methyl methane-sulfonate. Mustard Gas. Osmium and its compounds ...
http://dohs.ors.od.nih.gov/safety_data_sheets.htm
dohs.ors.od.nih.gov
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summary
Cerebral blood volume, genotype and chemosensitivity in ...
... as lipophilic drugs (procarbazine, lomustine and temozolomide), which easily ... according to standard clinical protocols [22]: lomustine (CCNU) (110 mg/m2) ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pub...
www.pubmedcentral.nih.gov
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summary
CeeNU Official FDA information, side effects and uses.
Accurate, FDA approved CeeNU information for healthcare professionals and ... CeeNUŽ (lomustine) (CCNU) is one of the nitrosoureas used in the treatment of ...
http://www.drugs.com/pro/ceenu.html
www.drugs.com
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summary
Melanoma and other skin cancers
A study published in The Lancet indicates that the best ways to avoid sun damage ... Fabrics that are thick and tightly woven offer the best protection. ...
http://adam.about.com/reports/Melanoma-and-other-skin-cancers.htm
adam.about.com
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summary
[Chemosensitivity test on brain tumors] [Neurocirugia (Astur). 2008 ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... to lomustine (CCNU) and vincristine. ...
http://www.ncbi.nlm.nih.gov/pubmed/18335150
www.ncbi.nlm.nih.gov
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summary
ChemIDPlus/HSDB 13909-09-6 Chemical - National Toxicology Program
Methyl CCNU. N-(2-CHLOROETHYL)-N'-(4-METHYLCYCLOHEXYL)-N-NITROSOUREA (9CI) ... Lomustine, methyl- Methyl-CCNU. NCI-C04955. Semustine ...
http://ntp.niehs.nih.gov/index.cfm?objectid=E87DA45E-BDB5-82F8-F288C88280AC2B0F
ntp.niehs.nih.gov
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summary
methyl-CCNU Information from Drugs.com
... CCNU medical ... Or browse a complete list of drug names A B C D E F G H I J K L M N O P ... agent resembling carmustine (BCNU) and lomustine (CCNU) ...
http://www.drugs.com/dict/methyl-ccnu.html
www.drugs.com
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summary
Chemotherapy regimens - Wikipedia, the free encyclopedia
Procarbazine, CCNU (lomustine), vincristine. Brain tumors. ProMACE-MOPP ... (Carmustine, Fotemustine, Lomustine, Nimustine, Prednimustine, Ranimustine, ...
http://en.wikipedia.org/wiki/Chemotherapy_regimens
en.wikipedia.org
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summary
Phase 2 trial of BCNU plus irinotecan in adults with malignant glioma
Nitrosoureas including CCNU (lomustine) and BCNU (1,3-bis(2-chloroethyl)-1 ... MR, minor response; OS, overall survival; PCV, procarbazine, CCNU [lomustine] ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1871982
www.pubmedcentral.nih.gov
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summary
eMedicine - Primitive Neuroectodermal Tumors of the Central Nervous ...
Primitive neuroectodermal tumors (PNET) are neoplasms of which ... are not limited to, lomustine (CCNU), vincristine, cisplatin, etoposide (VP-16) ...
http://www.emedicine.com/neuro/topic326.htm
www.emedicine.com
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summary
CeeNU
CeeNU (lomustine) should be administered under the supervision of a qualified ... CeeNUŽ (lomustine) (CCNU) is one of the nitrosoureas used in the treatment of ...
http://www.drugs.com/pro/ceenu.html?printable=1
www.drugs.com
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summary
MOA-118-drugs-Jan99
Table 1. Database for drugs analyzed in this study. 2. Mechanism ... Lomustine (CCNU) 79037. 4.35. 0.31. 56. 38.9. Di. 5-6-Dihydro-5-azacytidine. 264880. 4.63 ...
http://discover.nci.nih.gov/nature2000/paper/Tab1.xls
discover.nci.nih.gov
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summary
Ceenu
Information for Ceenu on Drugs.com. May include images, interactions and ... CeeNUŽ (lomustine) (CCNU) is one of the nitrosoureas used in the treatment of ...
http://www.drugs.com/search.php?searchterm=Ceenu
www.drugs.com
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summary
CDC Smallpox | Medicines Contraindicating Receipt of Smallpox Vaccine
Home page for all CDC smallpox information. Includes ... Lomustine. CeeNuŽ (CCNU) A. Mechlorethamine HCI. MustargenŽ A. Mechlorethamine HCI. Nitrogen Mustard ...
http://www.bt.cdc.gov/agent/smallpox/vaccination/immuno_suppress_meds.asp
www.bt.cdc.gov
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summary
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