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what is 'irinotecan'? Definition for irinotecan Irinotecan is a chemotherapy agent that is a topoisomerase 1 inhibitor . Chemically, it is a semisynthetic analogue of the natural alkaloid camptothecin . Its main use is in colon cancer , particularly in combination with other chemotherapy agents. more Irinotecan is a chemotherapy agent that is a topoisomerase 1 inhibitor . Chemically, it is a semisynthetic analogue of the natural alkaloid camptothecin . Its main use is in colon cancer , particularly in combination with other chemotherapy agents. This includes the regimen FOLFIRI which consists of infusional 5-fluorouracil , leucovorin , and irinotecan. less diagnoses treated with 'irinotecan' 1 - 5 of 9 diagnosis Lynch Syndromes I and II hereditary nonpolyposis colorectal cancer web search for: irinotecan and Lynch Syndromes I and II carcinoma pancreas pancreas cancer web search for: irinotecan and carcinoma pancreas esophageal carcinoma cancer of esophagus web search for: irinotecan and esophageal carcinoma gastric carcinoma cancer stomach web search for: irinotecan and gastric carcinoma metastases spread of malignant tumors to other body sites web search for: irinotecan and metastases small cell lung carcinoma rapidly growing cancer lung web search for: irinotecan and small cell lung carcinoma malignancy cancer web search for: irinotecan and malignancy colon cancer large bowel cancer web search for: irinotecan and colon cancer small intestine carcinoma small bowel cancer web search for: irinotecan and small intestine carcinoma for more please login, login is free (click to login) related procedures when taking 'irinotecan' 1 - 5 of 178 procedures Biopsy web search for: irinotecan and Biopsy CT scan web search for: irinotecan and CT scan Abdominal CAT Scan web search for: irinotecan and Abdominal CAT Scan Complete Blood Count web search for: irinotecan and Complete Blood Count Chemotherapy Use of chemical substances to treat disease web search for: irinotecan and Chemotherapy Cytodiagnosis web search for: irinotecan and Cytodiagnosis Radiation Therapy Use of ionizing radiation or xrays for medical imaging or to treat cancer web search for: irinotecan and Radiation Therapy Brush Cytology web search for: irinotecan and Brush Cytology Endoscopic surgery web search for: irinotecan and Endoscopic surgery External Beam Radiation web search for: irinotecan and External Beam Radiation Carcinoembryonic Antigen (CEA) web search for: irinotecan and Carcinoembryonic Antigen (CEA) Chest X-ray Radiological technique to image the chest web search for: irinotecan and Chest X-ray Tumor markers web search for: irinotecan and Tumor markers Liver Function Tests elevated liver enzymes web search for: irinotecan and Liver Function Tests CT chest web search for: irinotecan and CT chest Complete metabolic panel web search for: irinotecan and Complete metabolic panel Magnetic Resonance Imaging (MRI) web search for: irinotecan and Magnetic Resonance Imaging (MRI) Photodynamic therapy web search for: irinotecan and Photodynamic therapy serum electrolytes web search for: irinotecan and serum electrolytes Endoscopic ultrasonography Endoscopic Ultrasound web search for: irinotecan and Endoscopic ultrasonography for more please login, login is free (click to login) related medication for 'irinotecan' 1 - 5 of 95 drugs paclitaxel web search for: irinotecan and paclitaxel cisplatin web search for: irinotecan and cisplatin capecitabine web search for: irinotecan and capecitabine doxorubicin web search for: irinotecan and doxorubicin methotrexate web search for: irinotecan and methotrexate gemcitabine web search for: irinotecan and gemcitabine topotecan web search for: irinotecan and topotecan fluorouracil(adrucil ) web search for: irinotecan and fluorouracil(adrucil ) docetaxel(taxotere ) web search for: irinotecan and docetaxel(taxotere ) doxorubicin(adriamycin) web search for: irinotecan and doxorubicin(adriamycin) etoposide web search for: irinotecan and etoposide 5-fluorouracil (5-fu) web search for: irinotecan and 5-fluorouracil (5-fu) bleomycin web search for: irinotecan and bleomycin erlotinib web search for: irinotecan and erlotinib vinorelbine web search for: irinotecan and vinorelbine docetaxel web search for: irinotecan and docetaxel ifosfamide web search for: irinotecan and ifosfamide oxaliplatin web search for: irinotecan and oxaliplatin 5-fluorouracil web search for: irinotecan and 5-fluorouracil epirubicin(ellence , epirubicin hydrochloride) web search for: irinotecan and epirubicin(ellence , epirubicin hydrochloride) for more please login, login is free (click to login) The following are types of physicians relevant for 'irinotecan'. related types of physicians 'family practitioner, internist, oncologist' show local physicians postal code Find Local stars represent relevance to topic not rating more The results are computer generated suggestions to help you find a physician. MEDgle does not recommend any particular type of physician or claim to be complete or accurate in the providers and specialties suggested. web search results for 'irinotecan'? Results 1 - 50 - irinotecan Irinotecan - Wikipedia, the free encyclopedia Irinotecan is a chemotherapy agent that is a topoisomerase ... Irinotecan Pathway on ... (Camptothecin, Topotecan, Irinotecan, Rubitecan, Belotecan) II ... http://en.wikipedia.org/wiki/Irinotecan   en.wikipedia.org - summary irinotecan medical facts from Drugs.com ... reviewed irinotecan patient information - includes irinotecan description, dosage ... Irinotecan can cause severe diarrhea, which can be life-threatening if ... http://www.drugs.com/mtm/irinotecan.html   www.drugs.com - summary Irinotecan ... for Irinotecan. ... Irinotecan is an antitumor drug that interferes with how cancer ... Irinotecan should be administered only under the supervision of a ... http://www.webmd.com/cancer/irinotecan   www.webmd.com - summary Irinotecan - Yahoo! Health Your doctor may recommend you have an anti-diarrhea medicine such as loperamide (Imodium) available at all times while you are receiving irinotecan. The anti ... http://health.yahoo.com/coloncancer-medications/irinotecan/h...   health.yahoo.com - summary Camptosar Injection (Irinotecan Hydrochloride) Drug Information: Uses ... Learn about the prescription medication Camptosar Injection (Irinotecan Hydrochloride), drug uses, dosage, side effects, drug interactions, warnings, and patient ... http://www.rxlist.com/camptosar-inj-drug.htm   www.rxlist.com - summary Irinotecan: Drug Information Provided by Lexi-Comp: Merck Manual ... The dose of irinotecan should be reduced if there is a clinically significant ... Irinotecan and its active metabolite (SN-38) bind reversibly to topoisomerase ... http://www.merck.com/mmpe/lexicomp/irinotecan.html   www.merck.com - summary IRINOTECAN - INJECTION (Camptosar) side effects, medical uses, and drug ... Read more about the prescription drug IRINOTECAN - INJECTION. ... Your doctor may temporarily stop irinotecan if severe diarrhea continues. ... http://www.medicinenet.com/irinotecan-injection/article.htm   www.medicinenet.com - summary Irinotecan (Intravenous Route) - MayoClinic.com Mayo Clinic offers award-winning medical and health information and tools for healthy living. ... Irinotecan interferes with the growth of cancer cells, which ... http://www.mayoclinic.com/health/drug-information/DR600805/M...   www.mayoclinic.com - summary MedlinePlus Drug Information: Irinotecan Injection Before you begin your treatment with irinotecan, talk to your doctor about what ... You should not become pregnant while you are receiving irinotecan. ... http://www.nlm.nih.gov/medlineplus/druginfo/meds/a608043.html   www.nlm.nih.gov - summary Phase 1 trial of irinotecan plus BCNU in patients with progressive or ... Irinotecan is a topoisomerase I inhibitor previously shown to be active in the ... Irinotecan dose escalation occurred independently within 2 strata: patients ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1871988   www.pubmedcentral.nih.gov - summary Irinotecan toxicity. Irinotecan toxicity. Anthony L. ... Adjusting irinotecan's dose to the degree of hepatic insufficiency is now established. ... irinotecan. Camptothecin ... http://www.ncbi.nlm.nih.gov/pubmed/18660722   www.ncbi.nlm.nih.gov - summary Irinotecan Not Superior in SCLC - National Cancer Institute In contrast to earlier findings, irinotecan and cisplatin were no better than ... Small cell lung cancer, irinotecan, etoposide, cisplatin. ... http://cme.nci.nih.gov/clinicaltrials/results/irinotecan-and-SCLC0505   cme.nci.nih.gov - summary irinotecan - PubChem Public Chemical Database PubChem Compound Summary ... CAMPTOSAR Injection (irinotecan hydrochloride injection) is an antineoplastic ... Irinotecan hydrochloride was clinically ... http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=3750   pubchem.ncbi.nlm.nih.gov - summary Irinotecan - Definition of Irinotecan Irinotecan is a chemotherapy drug used in the treatment of several types of cancers, including ovarian, lung, and colorectal cancer. http://coloncancer.about.com/od/glossaries/g/Irinotecan.htm   coloncancer.about.com - summary Irinotecan ((+)-Irinotecan) - NextBio Irinotecan is a derivative of camptothecin. ... Objective response of multiply recurrent low-grade gliomas to bevacizumab and irinotecan. ... http://www.nextbio.com/b/search/ov.nb?q=(%2B)-Irinotecan&type=COMPOUND   www.nextbio.com - summary Irinotecan Ineffective After Colon Cancer Surgery - National Cancer ... Irinotecan should not be added to 5-fluorouracil (5-FU) and leucovorin in the ... Irinotecan Not Effective in Adjuvant Therapy for Colon Cancer ... http://www.nci.nih.gov/clinicaltrials/results/irinotecan0807   www.nci.nih.gov - summary Irinotecan consumer information from Drugs.com Irinotecan patient ... Irinotecan interferes with the growth of cancer cells, which are ... may occur after treatment with irinotecan has been stopped. ... http://www.drugs.com/cons/Irinotecan.html   www.drugs.com - summary irinotecan-injection Glossary of Terms with Definitions on MedicineNet.com irinotecan-injection glossary includes a list of irinotecan-injection related medical definitions and related links on MedicineNet.com http://www.medicinenet.com/irinotecan-injection/glossary.htm   www.medicinenet.com - summary Irinotecan - Yahoo! Health Irinotecan is an ... Irinotecan should be administered only under the supervision of a medical oncologist. ... Irinotecan can cause birth defects. ... http://health.yahoo.com/cancer-medications/irinotecan/healthwise--tw9452.html   health.yahoo.com - summary Drug Information for Irinotecan IV - WebMD Find medical information for Irinotecan IV including side effects, drug interactions, images and pictures, medication uses, warnings, user ratings and reviews. http://www.webmd.com/drugs/drug-13700-Irinotecan%20IV.aspx?d...   www.webmd.com - summary Erbitux (Cetuximab) Drug Information: Uses, Side Effects, Drug ... Learn about the prescription medication Erbitux (Cetuximab), drug uses, ... Erbitux®, in combination with irinotecan, is indicated for the treatment of EGFR ... http://www.rxlist.com/erbitux-drug.htm   www.rxlist.com - summary Irinotecan plus folinic acid/continuous 5-fluorouracil as simplified ... Furthermore, irinotecan schedules of weekly and of once every two or three weeks ... In contrast to the irinotecan and bolus FA/5-FU regimen, which has attracted ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=497044   www.pubmedcentral.nih.gov - summary Irinotecan in esophageal cancer. Irinotecan (CPT-11, Camptosar) has shown promising activity in a number of ... Full doses of weekly irinotecan (65 mg/m2) and cisplatin (30 mg/m2) could be ... http://www.ncbi.nlm.nih.gov/pubmed/14569846   www.ncbi.nlm.nih.gov - summary Cetuximab Combo Confirmed Effective - National Cancer Institute ... cancer and that the cetuximab/irinotecan combination is more effective than cetuximab alone. ... cetuximab (Erbitux®) and irinotecan (CPT-11) shrank tumors ... http://www.nci.nih.gov/clinicaltrials/results/cetuximab-combo-effective0603   www.nci.nih.gov - summary Loperamide: Drug Information Provided by Lexi-Comp: Merck Manual ... Irinotecan-induced diarrhea (unlabeled use): 4 mg after first loose or frequent ... ML, Eckardt JR, Kuhn JG, et al, "Phase II Trial of Irinotecan in Patients With ... http://www.merck.com/mmpe/lexicomp/loperamide.html   www.merck.com - summary bexarotene and Irinotecan Drug Interactions bexarotene and Irinotecan Drug Interactions. Drug-drug and drug-food interactions between ... In one study, irinotecan pharmacokinetics were determined ... http://www.drugs.com/drug-interactions/bexarotene_d04507_irinotecan_d04026.html   www.drugs.com - summary S 1 (combination)(S-1) - NextBio ... carcinoma interferon-alpha irinotecan neutropenia non-small ... Phase I/II study of S-1 combined with irinotecan for metastatic advanced gastric cancer. ... http://www.nextbio.com/b/home/home.nb?q=S-1   www.nextbio.com - summary Irinotecan plus fluorouracil and leucovorin for metastatic colorectal ... Irinotecan prolongs survival in patients with colorectal cancer that is ... A third group of patients received irinotecan alone. ... http://www.ncbi.nlm.nih.gov/pubmed/11006366   www.ncbi.nlm.nih.gov - summary Drug Information for Fosphenytoin Inj - WebMD Find medical information for Fosphenytoin Inj including side effects, drug interactions, ... Altered irinotecan metabolism in a patient receiving phenytoin. ... http://www.webmd.com/drugs/drug-13896-Fosphenytoin+Inj.aspx?...   www.webmd.com - summary Camptosar Information from Drugs.com Camptosar (irinotecan) is used to treat cancers of the colon and rectum. ... Irinotecan injection is available with a prescription under the brand name Camptosar. ... http://www.drugs.com/camptosar.html   www.drugs.com - summary Colon cancer: Treatment - Health Professional Information [NCI PDQ ... This PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based ... using an irinotecan-based regimen ... http://health.yahoo.com/other-other/colon-cancer-treatment-h...   health.yahoo.com - summary Optical Imaging of Tumor Cells in Hollow Fibers: Evaluation of the ... Irinotecan hydrochloride (Camptosar, 20 mg/ml; Pharmacia and Upjohn Co., New ... Synergistic effect of gemcitabine and irinotecan (CPT-11) on breast and small ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1950435   www.pubmedcentral.nih.gov - summary Definition of irinotecan - NCI Dictionary of Cancer Terms Irinotecan blocks certain enzymes needed for cell division and DNA repair, and ... irinotecan hydrochloride, iris, irofulven, iron, iron overload ... http://www.nci.nih.gov/Templates/db_alpha.aspx?CdrID=45391   www.nci.nih.gov - summary Gastrointestinal Cancer Models Irinotecan (CPT-11, Camptosar) converts the normal nuclear enzyme, topoisomerase ... More recently, the combination of irinotecan, 5-FU, and leucovorin (IFL) has ... http://emice.nci.nih.gov/mouse_models/organ_models/gastro_models   emice.nci.nih.gov - summary Pharmacogenomics: When drug treatment becomes personalized medicine ... Pharmacogenomics is a type of personalized medicine that studies how you ... how the body breaks down irinotecan (Camptosar), a chemotherapy drug used to ... http://www.mayoclinic.com/health/personalized-medicine/CA00078   www.mayoclinic.com - summary Drugs A-Z List - C on RxList Browse an A-Z list of Brand and Generic drugs to learn about your prescription medication. ... Camptosar Injection (Irinotecan Hydrochloride) Canasa (Mesalamine) ... http://www.rxlist.com/drugs/alpha_c.htm   www.rxlist.com - summary Treatment with 5-FU, Oxaliplatin, and Irinotecan Enables Resection of ... Cancer research - journal article. Treatment with 5-FU, Oxaliplatin, and Irinotecan Enables Resection of Metastases in Patients with Initially Unresectable ... http://coloncancer.about.com/od/journalarticlesfrom2006/a/2006Abstract22.htm   coloncancer.about.com - summary Camptosar Official FDA information, side effects and uses. Accurate, FDA approved Camptosar information for healthcare professionals ... Irinotecan serves as a water-soluble precursor of the lipophilic metabolite SN ... http://www.drugs.com/pro/camptosar.html   www.drugs.com - summary Role of cytokines (TNF-alpha, IL-1beta and KC) in the pathogenesis of ... INTRODUCTION: Irinotecan (CPT-11) is an inhibitor of DNA topoisomerase I and is ... irinotecan. keratinocyte-derived chemokines. Thalidomide. Pentoxifylline ... http://www.ncbi.nlm.nih.gov/pubmed/17624531?ordinalpos=76&it...   www.ncbi.nlm.nih.gov - summary Drug Information for Atazanavir Oral - WebMD Find medical information for Atazanavir Oral including side effects, drug interactions, images and pictures, ... ATAZANAVIR/IRINOTECAN. PROTEASE ... http://www.webmd.com/drugs/drug-76254-Atazanavir+Oral.aspx?d...   www.webmd.com - summary IFL chemotherapy - Wikipedia, the free encyclopedia ... of concurrent treatment with irinotecan, leucovorin (folinic acid), and ... Camptotheca (Camptothecin, Topotecan, Irinotecan, Rubitecan, Belotecan) II ... http://en.wikipedia.org/wiki/IFL_chemotherapy   en.wikipedia.org - summary Efficacy, safety, and cost of new anticancer drugs ... results from randomised trials of irinotecan and oxaliplatin (not considered by ... combination.2-2 2-3 Irinotecan and oxaliplatin are not even mentioned ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1124759   www.pubmedcentral.nih.gov - summary NIGMS -- Findings, September 2002: Bench to Bedside An online magazine that highlights two NIGMS-funded scientists who are doing ... reaction to a chemotherapy drug called irinotecan, which is used to treat a ... http://publications.nigms.nih.gov/findings/sept02/bench.html   publications.nigms.nih.gov - summary Dilantin (Phenytoin) Drug Information: Uses, Side Effects, Drug ... Learn about the prescription medication Dilantin (Phenytoin), drug uses, ... some drugs to treat cancer (e.g., imatinib, irinotecan), corticosteroids (e. ... http://www.rxlist.com/dilantin-drug.htm   www.rxlist.com - summary Family 1 uridine-5'-diphosphate glucuronosyltransferases (UGT1A): from ... ... effects of the anticancer drug irinotecan and the antiviral proteinase inhibitor ... irinotecan. atazanavir. Bilirubin. Camptothecin ... http://www.ncbi.nlm.nih.gov/pubmed/18491077   www.ncbi.nlm.nih.gov - summary Erbitux ImClone - Treatment for Advanced Colorectal Cancer Browse all medications A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ... intravenously with irinotecan, or alone if patients cannot tolerate irinotecan. ... http://www.drugs.com/newdrugs/erbitux-imclone-advanced-color...   www.drugs.com - summary Financial considerations in the conduct of multi-centre randomised ... ... survival times for irinotecan and oxaliplatin did not warrant the costs ... NICE issued guidelines recommending that irinotecan should be used only after ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1781076   www.pubmedcentral.nih.gov - summary IRINOTECAN - INJECTION (Camptosar) side effects, medical uses, and drug ... Read doctor-produced health and medical information written for you to make informed decisions about ... irinotecan-injection, camptosar index. irinotecan ... http://www.medicinenet.com/irinotecan-injection/index.htm   www.medicinenet.com - summary Colorectal Cancer-Medications Information on medications for colorectal cancer. ... Capecitabine, sometimes combined with irinotecan or oxaliplatin. ... Irinotecan, sometimes combined with 5-FU. ... http://www.webmd.com/colorectal-cancer/tc/colorectal-cancer-medications   www.webmd.com - summary Modulation of irinotecan metabolism by ketoconazole. PURPOSE: Irinotecan (CPT-11) is a prodrug of SN-38 and has been registered for ... the role of CYP3A4 in irinotecan pharmacology, we evaluated the consequences of ... http://www.ncbi.nlm.nih.gov/pubmed/12118026?dopt=Abstract   www.ncbi.nlm.nih.gov - summary show more 1  2

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