Hydroxyzine (pronounced /ha??dr?ks?zi?n/ ) is a first-generation antihistamine, of the piperazine class that is an H 1 receptor antagonist. It was synthesised in the early 1950s and the medicinal formulation of this drug was announced in the 04 August 1956 issue of Chemistry Week . more

Hydroxyzine (pronounced /ha??dr?ks?zi?n/ ) is a first-generation antihistamine, of the piperazine class that is an H 1 receptor antagonist. It was synthesised in the early 1950s and the medicinal formulation of this drug was announced in the 04 August 1956 issue of Chemistry Week . It is used primarily as an antihistamine for the treatment of itches and irritations, an antiemetic for the reduction of nausea , as a weak analgesic by itself and as an opioid potentiator, and as an anxiolytic ''' for the treatment of anxiety''' . [ 1 ] less