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what is 'diepoxybutane (deb)'? Definition for diepoxybutane (deb) diepoxybutane (deb) is medication used for such diagnoses as: myelodysplasia. diagnoses treated with 'diepoxybutane (deb)' 1 - 1 of 1 diagnosis myelodysplasia ineffective production of blood cells and predisposition to cancer web search for: diepoxybutane (deb) and myelodysplasia related procedures when taking 'diepoxybutane (deb)' 1 - 5 of 27 procedures Biopsy bone marrow web search for: diepoxybutane (deb) and Biopsy bone marrow Blood, Platelet Count Platelet Count web search for: diepoxybutane (deb) and Blood, Platelet Count Bone Marrow Aspiration web search for: diepoxybutane (deb) and Bone Marrow Aspiration CD55 (decay accelerating factor [DAF]) web search for: diepoxybutane (deb) and CD55 (decay accelerating factor [DAF]) CD59 (membrane inhibitor of reactive lysis [MIRL]) web search for: diepoxybutane (deb) and CD59 (membrane inhibitor of reactive lysis [MIRL]) CMV serology web search for: diepoxybutane (deb) and CMV serology Central venous catheter web search for: diepoxybutane (deb) and Central venous catheter Chromosomal analysis web search for: diepoxybutane (deb) and Chromosomal analysis Complete Blood Count web search for: diepoxybutane (deb) and Complete Blood Count Epstein Barr Virus serology web search for: diepoxybutane (deb) and Epstein Barr Virus serology Fluorescent in situ hybridization (FISH) web search for: diepoxybutane (deb) and Fluorescent in situ hybridization (FISH) HLA (human leukocyte antigen) web search for: diepoxybutane (deb) and HLA (human leukocyte antigen) Hematopoietic stem cell transplantation web search for: diepoxybutane (deb) and Hematopoietic stem cell transplantation Hemoglobin electrophoresis web search for: diepoxybutane (deb) and Hemoglobin electrophoresis Histocompatibility testing web search for: diepoxybutane (deb) and Histocompatibility testing Human Immunodeficiency Virus (HIV) serology web search for: diepoxybutane (deb) and Human Immunodeficiency Virus (HIV) serology Immunosuppressive therapy web search for: diepoxybutane (deb) and Immunosuppressive therapy Peripheral blood smear web search for: diepoxybutane (deb) and Peripheral blood smear Polymerase Chain Reaction (PCR) web search for: diepoxybutane (deb) and Polymerase Chain Reaction (PCR) Reticulocyte count web search for: diepoxybutane (deb) and Reticulocyte count for more please login, login is free (click to login) related medication for 'diepoxybutane (deb)' 1 - 5 of 9 drugs amifostine web search for: diepoxybutane (deb) and amifostine azacitidine web search for: diepoxybutane (deb) and azacitidine cladribine (2-cda) web search for: diepoxybutane (deb) and cladribine (2-cda) cytosine arabinoside web search for: diepoxybutane (deb) and cytosine arabinoside decitabine web search for: diepoxybutane (deb) and decitabine erythropoietin web search for: diepoxybutane (deb) and erythropoietin granulocyte colony-stimulating factor [g-csf]) web search for: diepoxybutane (deb) and granulocyte colony-stimulating factor [g-csf]) hydroxyurea web search for: diepoxybutane (deb) and hydroxyurea lenalidomide web search for: diepoxybutane (deb) and lenalidomide for more please login, login is free (click to login) The following are types of physicians relevant for 'diepoxybutane (deb)'. related types of physicians 'family practitioner, hematologist, internist, oncologist' show local physicians postal code Find Local stars represent relevance to topic not rating more The results are computer generated suggestions to help you find a physician. MEDgle does not recommend any particular type of physician or claim to be complete or accurate in the providers and specialties suggested. web search results for 'diepoxybutane (deb)'? Results 1 - 50 - diepoxybutane (deb) The 5'-GNC Site for DNA Interstrand Cross-Linking is Conserved for ... 1,2,3,4-Diepoxybutane (DEB) is a cytotoxic bifunctional alkylating agent that ... On the other hand, S,S DEB is believed to be the active metabolite of the pro ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1599837   www.pubmedcentral.nih.gov - summary International Fanconi Anemia Registry: relation of clinical symptoms to ... ... cross-linking agents such as diepoxybutane (DEB) has been used to facilitate the ... Data from DEB-induced chromosomal breakage studies of 328 peripheral blood ... http://www.ncbi.nlm.nih.gov/pubmed/2917181   www.ncbi.nlm.nih.gov - summary eMedicine - Anemia, Fanconi : Article Excerpt by Blanche P Alter Fanconi anemia (FA) is the most frequently reported of the rare inherited bone marrow failure syndromes, with more ... such as diepoxybutane (DEB) or mitomycin ... http://www.emedicine.com/ped/byname/Anemia--Fanconi.htm   www.emedicine.com - summary ChemIDPlus/HSDB 299-75-2 Toxicity - National Toxicology Program ... product, dl-1,2:3,4-diepoxybutane (DEB), were studied in Chinese hamster ovary, AS52, cells. ... dl-1,2:3,4-diepoxybutane is cytotoxic and mutagenic at a ... http://ntp.niehs.nih.gov/index.cfm?objectid=E87F35BB-BDB5-82F8-F39DEF93A1F9C1E0   ntp.niehs.nih.gov - summary Site specific N6-(2-hydroxy-3,4-epoxybut-1-yl)aden...[Chem Res Toxicol ... PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... 3,4-Diepoxybutane (DEB) is an ... http://www.ncbi.nlm.nih.gov/pubmed/17355152?ordinalpos=6&ito...   www.ncbi.nlm.nih.gov - summary Transfection of normal human and Chinese hamster DNA corrects ... ... and clastogenic effects of the difunctional alkylating agent diepoxybutane (DEB) ... At this dose of DEB, the clonogenicity of normal fibroblasts was ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=298961   www.pubmedcentral.nih.gov - summary HPLC-ESI+-MS/MS analysis of N7-guanine-N7-guanine ...[Chem Res Toxicol ... PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... 3,4-diepoxybutane (DEB) appears to be ... http://www.ncbi.nlm.nih.gov/pubmed/17455958?ordinalpos=4&ito...   www.ncbi.nlm.nih.gov - summary eMedicine - Anemia, Fanconi : Article Excerpt by: Blanche P Alter, MD, MPH Anemia, Fanconi - Fanconi anemia (FA) is the most frequently reported of the rare inherited bone marrow failure ... as diepoxybutane (DEB) or mitomycin ... http://www.emedicine.com/ped/byname/anemia-fanconi.htm   www.emedicine.com - summary Diepoxybutane forms a monoadduct with B-form (dG-dC)n.(dG-dC)n and a ... ... characteristics of the reactions of DL-diepoxybutane (DEB) with (dG-dC)n.(dG-dC) ... DEB does react with right-handed B-DNA since less salt is required to convert ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=321895   www.pubmedcentral.nih.gov - summary Mutagenesis of the supF gene by stereoisomers of 1...[Chem Res Toxicol ... PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... 2,3,4-diepoxybutane (DEB) is a key ... http://www.ncbi.nlm.nih.gov/pubmed/17428069?ordinalpos=5&ito...   www.ncbi.nlm.nih.gov - summary Somatic mosaicism in Fanconi anemia: Evidence of genotypic reversion in ... ... to DNA cross-linking agents such as diepoxybutane (DEB) and mitomycin C (MMC) (9) ... DEB. diepoxybutane. LCL. lymphoblastoid cell line. PBL. peripheral ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=30172   www.pubmedcentral.nih.gov - summary Fanconi Anemia -- GeneReviews -- NCBI Bookshelf ... linking agent such as diepoxybutane (DEB) or mitomycin C (MMC) ... Fanconi anemia diagnosis and the diepoxybutane (DEB) test. Exp Hematol. 1993; 21: 731?3. ... http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=gene&partid=1401   www.ncbi.nlm.nih.gov - summary 1,3-BUTADIENE: HUMAN HEALTH ASPECTS diepoxide 1,2,3,4-diepoxybutane, or DEB, or hydrolysed ... as DEB has not been detected in tissues of. exposed humans), and hydrolysis of EB and DEB in rats ... http://www.who.int/ipcs/publications/cicad/en/cicad30.pdf   www.who.int - summary eMedicine - Anemia, Fanconi : Article by Blanche P Alter Fanconi anemia (FA) is the most frequently reported of the rare inherited bone marrow failure syndromes, with more ... such as diepoxybutane (DEB) or mitomycin ... http://www.emedicine.com/ped/topic3022.htm   www.emedicine.com - summary A Tester System for Detecting Each of the Six Base-Pair Substitutions ... ... mutagenic activity of diepoxybutane in yeast. Mutat Res. ... rad3 mutant of Saccharomyces cerevisiae after treatment with diepoxybutane (DEB). Mol Gen Genet. ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1204453   www.pubmedcentral.nih.gov - summary Fanconi Anemia linking agent such as diepoxybutane (DEB) or mitomycin C (MMC). Molecular ... chromosomal breakage or rearrangement in the presence of diepoxybutane (DEB) or ... http://www.ncbi.nlm.nih.gov/bookshelf/picrender.fcgi?book=ge...   www.ncbi.nlm.nih.gov - summary Transplantation: Unrelated donor bone marrow transplantation for the ... ... on diepoxybutane (DEB) sensitivity (mean chromosome breaks per cell), DEB T-cell ... An effect of DEB T-cell mosaicism was not observed on platelet recovery. ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1801062   www.pubmedcentral.nih.gov - summary eMedicine - Myelodysplasia : Article by Sharon M Castellino Myelodysplasia encompasses a heterogenous group of disorders that result in ... A Fanconi screen using diepoxybutane (DEB) or mitomycin C stimulation reveals ... http://www.emedicine.com/ped/topic1526.htm   www.emedicine.com - summary Cytogenetic studies in lymphocytes of patients with rectal cancer. Diepoxybutane (DEB), 4-nitroquinoline-1-oxide (NQO), and bleomycin were used as ... detected of the average spontaneous, DEB- and bleomycin (G2)-induced chromosome ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1521168   www.pubmedcentral.nih.gov - summary Microcell mediated chromosome transfer maps the Fa...[Nat Genet. 1995 ... PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... C (MMC) and diepoxybutane (DEB) ... http://www.ncbi.nlm.nih.gov/pubmed/7581463   www.ncbi.nlm.nih.gov - summary eMedicine - Chromosomal Breakage Syndromes : Article by Margot Kaelbling ataxia telangiectasia, AT, Louis-Bar syndrome, Bloom syndrome, BS, Fanconi anemia, FA, pancytopenia dysmelia, ... diepoxybutane (DEB) or mitomycin C (MMC) ... http://www.emedicine.com/ped/topic2862.htm   www.emedicine.com - summary HPRT Mutations in Lymphocytes from 1,3-Butadiene-Exposed Workers in China ... 3-butene (EB), 1,2,3,4-diepoxybutane (DEB), and 3,4-epoxy-1,2-butanediol (EB ... Although DEB is the most potent mutagen, reports have suggested that it is not a ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2235214   www.pubmedcentral.nih.gov - summary Expression cloning of a cDNA for the major Fanconi anaemia gene, FAA. Lo Ten Foe JR, Rooimans MA, Bosnoyan-Collins L, Alon N, Wijker M, Parker L, ... (cross-linking) agents, such as diepoxybutane (DEB) and mitomycin C (MMC) ... http://www.ncbi.nlm.nih.gov/pubmed/8896563   www.ncbi.nlm.nih.gov - summary Chemical crosslinking of elongation factor G to the 23S RNA in 70S ... Journal List > Nucleic Acids Res > v.11(14); Jul 25, 1983. Summary. Selected ... coli ribosomes with the bifunctional, cleavable reagent diepoxybutane (DEB) ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=326095   www.pubmedcentral.nih.gov - summary Upregulated ATM Gene Expression and Activated DNA Crosslink?Induced ... Copyright 2008, The Feinstein Institute for Medical Research ... to DNA cross-linking agents such as mitomycin C (MMC) and diepoxybutane (DEB) ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2213892   www.pubmedcentral.nih.gov - summary Abstracts diepoxybutane (DEB), the most mutagenic. BD metabolite. DEB reacts with N-terminal ... exposed to 2.5 and 5 ppm DEB (4 weeks), the adduct was measured at 1.6 and 2.5 ... http://www.niehs.nih.gov/news/events/pastmtg/2006/easteuro/docs/abstracts.pdf   www.niehs.nih.gov - summary The identification of fanconi anemia genotypes by clastogenic stress. M M Cohen, S J Simpson, G R Honig, H S Maurer, J W Nicklas, and A O Martin ... The two agents used were diepoxybutane (DEB) and mitomycin C (MMC), previously ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1685444   www.pubmedcentral.nih.gov - summary The Broad-Spectrum Blast Resistance Gene Pi9 Encodes a Nucleotide ... ... with the chemical mutagen diepoxybutane (DEB), using the method described by Wang et al. ... M1 plants from the DEB-induced populations were allowed to ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1456263   www.pubmedcentral.nih.gov - summary Roberts Syndrome -- GeneReviews -- NCBI Bookshelf GeneReviews provides information about selected national organizations and ... interstrand cross-linking agent such as diepoxybutane (DEB) or mitomycin C (MMC) ... http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=gene&part=rbs   www.ncbi.nlm.nih.gov - summary Mutations of the Fanconi anemia group A gene (FAA) in Italian patients. Journal List > Am J Hum Genet > v.61(6); Dec 1997. Summary ... Fanconi anemia diagnosis and the diepoxybutane (DEB) test. Exp Hematol. 1993 Jun;21(6):731?733. ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1716093   www.pubmedcentral.nih.gov - summary Holt-Oram Syndrome -- GeneReviews -- NCBI Bookshelf GeneReviews provides information about selected national organizations and ... interstrand cross-linking agent such as diepoxybutane (DEB) or mitomycin C (MMC) ... http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=gene&part=hos   www.ncbi.nlm.nih.gov - summary Fanconi anemia manifesting as a squamous cell carcinoma of the hard ... Giulio Gasparini,#1 Gianluigi Longobardi,#1 Roberto Boniello,#1 Alessandro Di ... to DNA cross-linking agent such as diepoxybutane (DEB) and mitomycin (MML) ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1368969   www.pubmedcentral.nih.gov - summary The Fanconi anemia polypeptide FACC is localized to the cytoplasm. Journal List > Proc Natl Acad Sci U S A > v.91(14); Jul 5, ... Fanconi anemia diagnosis and the diepoxybutane (DEB) test. Exp Hematol. 1993 Jun;21(6):731?733. ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=44273   www.pubmedcentral.nih.gov - summary Baller-Gerold Syndrome -- GeneReviews -- NCBI Bookshelf GeneReviews provides information about selected national organizations and ... interstrand cross-linking agent such as diepoxybutane (DEB) or mitomycin C (MMC) ... http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=gene&part=bgs   www.ncbi.nlm.nih.gov - summary Interstrand Cross-Links Induce DNA Synthesis in Damaged and Undamaged ... ... cross-linking agents, such as diepoxybutane and mitomycin C, but not to ... Auerbach A D. Fanconi anaemia diagnosis and the diepoxybutane (DEB) test. Exp Hematol. ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=84414   www.pubmedcentral.nih.gov - summary SALL4-Related Disorders -- GeneReviews -- NCBI Bookshelf GeneReviews provides information about selected national organizations and ... cell cultivation in medium with DEB (diepoxybutane) and/or mitomycin C; see ... http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=gene&part=drrs   www.ncbi.nlm.nih.gov - summary BLAP75, an essential component of Bloom's syndrome protein complexes ... Journal List > EMBO J > v.24(7); Apr 6, 2005. Abstract. Full Text. PDF ... (MMC), hydroxyurea, aphidicolin and diepoxybutane (DEB), the percentage of cells ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1142546   www.pubmedcentral.nih.gov - summary Holt-Oram Syndrome of congenital heart malformation, most commonly ostium secundum atrial septal defect (ASD) ... cross-linking agent such as diepoxybutane (DEB) or mitomycin C (MMC) ... http://www.ncbi.nlm.nih.gov/bookshelf/picrender.fcgi?book=ge...   www.ncbi.nlm.nih.gov - summary Cancer Issue: Multiple Endocrine Neoplasia Type 1 (MEN1) as a Cancer ... ... the cross-linking agent diepoxybutane (DEB) [44] ... DEB. Diepoxybutane. MEFs. Mouse embryonic fibroblasts. RPA. Replication protein A. ES. Embryonic stem ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1994794   www.pubmedcentral.nih.gov - summary Baller-Gerold Syndrome craniosynostosis, manifest as abnormal shape of the skull (brachycephaly) ... cross-linking agent such as diepoxybutane (DEB) or mitomycin C (MMC). Molecular ... http://www.ncbi.nlm.nih.gov/bookshelf/picrender.fcgi?book=ge...   www.ncbi.nlm.nih.gov - summary SALL4-Related Disorders Okihiro syndrome) and acro-renal-ocular syndrome (AROS), two phenotypes ... (breaks, radial figures) after cell cultivation in medium with DEB (diepoxybutane) ... http://www.ncbi.nlm.nih.gov/bookshelf/picrender.fcgi?book=ge...   www.ncbi.nlm.nih.gov - summary Structural elucidation of a novel DNA-DNA cross-li...[Chem Res Toxicol ... PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... 3,4-diepoxybutane (DEB) is considered ... http://www.ncbi.nlm.nih.gov/pubmed/17305410?ordinalpos=7&ito...   www.ncbi.nlm.nih.gov - summary Preliminary communication: prenatal detection of the Fanconi Anemia ... Upon treatment with diepoxybutane (DEB), chromosome breakage increased to a level comparable to that reported earlier in DEB-treated FA heterozygous cells. ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1685672   www.pubmedcentral.nih.gov - summary Natural gene therapy in monozygotic twins with Fanconi anemia ... DNA cross-linking agents such as diepoxybutane (DEB) or mitomycin C (MMC).9,10 ... St Louis, MO) and diepoxybutane (DEB; Sigma-Aldrich) sensitivity, ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1895746   www.pubmedcentral.nih.gov - summary DNA repair decline during mouse spermiogenesis res...[DNA Repair (Amst ... PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... to diepoxybutane (DEB), a component ... http://www.ncbi.nlm.nih.gov/pubmed/18282746?ordinalpos=1&ito...   www.ncbi.nlm.nih.gov - summary Stabilization of (dG-dC)n.(dG-dC)n in the Z conformation by a ... ... diepoxybutane (DEB), stabilized this conformer so that it retained its structure ... dC)n in the B conformation with DEB did not prevent conversion to the Z ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=326592   www.pubmedcentral.nih.gov - summary Fanconi anaemia Fanconi anemia diagnosis and the diepoxybutane (DEB) test. Exp Hematol. 1993 Jun;21(6):731?733. ... evaluation of diepoxybutane sensitivity and cell cycle ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1735271   www.pubmedcentral.nih.gov - summary Leukemia and preleukemia in Fanconi anemia patient...[Cancer Genet ... PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE ... such as diepoxybutane (DEB) can be used ... http://www.ncbi.nlm.nih.gov/pubmed/1984836   www.ncbi.nlm.nih.gov - summary High Frequency of Large Intragenic Deletions in the Fanconi Anemia ... ... to DNA cross-linking agents, such as diepoxybutane (DEB) and mitomycin ... Auerbach AD (1993) Fanconi anemia diagnosis and the diepoxybutane (DEB) test. ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=12...   www.pubmedcentral.nih.gov - summary A locus for Fanconi anemia on 16q determined by homozygosity mapping. Fanconi anemia diagnosis and the diepoxybutane (DEB) test. Exp Hematol. 1993 Jun;21(6):731?733. ... of clinical symptoms to diepoxybutane sensitivity. Blood. ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1914713   www.pubmedcentral.nih.gov - summary show more 1  2

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