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cytarabine (ara-c)
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what is 'cytarabine (ara-c)'?
Definition for cytarabine (ara-c)
Cytarabine , or cytosine arabinoside , is a chemotherapy agent used mainly in the treatment of hematological malignancies such as acute myeloid leukemia (AML) and non-Hodgkin lymphoma . [ 1 ] It is also known as ara C .
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Cytarabine , or cytosine arabinoside , is a chemotherapy agent used mainly in the treatment of hematological malignancies such as acute myeloid leukemia (AML) and non-Hodgkin lymphoma . [ 1 ] It is also known as ara C . [ 2 ]
Cytarabine was discovered in Europe in the 1960s. It was approved by the United States Food and Drug Administration in June 1969, and was initially marketed in the US by Upjohn under the trade name Cytosar-U.
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diagnoses treated with 'cytarabine (ara-c)'
1 - 1 of
1
diagnosis
chronic myeloid leukemia
cancer of white blood cells
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cytarabine (ara-c) and chronic myeloid leukemia
related procedures when taking 'cytarabine (ara-c)'
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44
procedures
Abdominal CAT Scan
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cytarabine (ara-c) and Abdominal CAT Scan
Abdominal MRI
MRI of abdominal contents
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cytarabine (ara-c) and Abdominal MRI
Abdominal ultrasonography
Ultrasound of abdominal contents
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cytarabine (ara-c) and Abdominal ultrasonography
Activated partial thromboplastin time
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cytarabine (ara-c) and Activated partial thromboplastin time
BUN
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cytarabine (ara-c) and BUN
Banded chromosome analysis
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cytarabine (ara-c) and Banded chromosome analysis
Biopsy bone marrow
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cytarabine (ara-c) and Biopsy bone marrow
Blood, Platelet Count
Platelet Count
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cytarabine (ara-c) and Blood, Platelet Count
Bone Marrow Aspiration
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cytarabine (ara-c) and Bone Marrow Aspiration
Bone Marrow Transplant
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cytarabine (ara-c) and Bone Marrow Transplant
Breakpoint Cluster Region (BCR)
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cytarabine (ara-c) and Breakpoint Cluster Region (BCR)
Chemotherapy
Use of chemical substances to treat disease
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cytarabine (ara-c) and Chemotherapy
Chest X-ray
Radiological technique to image the chest
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cytarabine (ara-c) and Chest X-ray
Chromosomal analysis
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cytarabine (ara-c) and Chromosomal analysis
Complete Blood Count
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cytarabine (ara-c) and Complete Blood Count
Complete metabolic panel
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cytarabine (ara-c) and Complete metabolic panel
Cytochemical evaluation
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cytarabine (ara-c) and Cytochemical evaluation
Fluorescent in situ hybridization (FISH)
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cytarabine (ara-c) and Fluorescent in situ hybridization (FISH)
Hematopoietic stem cell transplantation
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cytarabine (ara-c) and Hematopoietic stem cell transplantation
Histocompatibility testing
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cytarabine (ara-c) and Histocompatibility testing
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related medication for 'cytarabine (ara-c)'
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17
drugs
arsenic trioxide(trisenox )
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cytarabine (ara-c) and arsenic trioxide(trisenox )
busulfan
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cytarabine (ara-c) and busulfan
busulfan(myleran , busulfex)
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cytarabine (ara-c) and busulfan(myleran , busulfex)
cyclophosphamide
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cytarabine (ara-c) and cyclophosphamide
cytarabine(cytosar-u , tarabine pfs)
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cytarabine (ara-c) and cytarabine(cytosar-u , tarabine pfs)
dasatinib
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cytarabine (ara-c) and dasatinib
dasatinib(sprycel )
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cytarabine (ara-c) and dasatinib(sprycel )
hydroxyurea
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cytarabine (ara-c) and hydroxyurea
hydroxyurea(hydrea)
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cytarabine (ara-c) and hydroxyurea(hydrea)
imatinib
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cytarabine (ara-c) and imatinib
imatinib(gleevec )
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cytarabine (ara-c) and imatinib(gleevec )
interferon alfa-2a(roferon-a )
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cytarabine (ara-c) and interferon alfa-2a(roferon-a )
interferon alfa-2b(intron a )
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cytarabine (ara-c) and interferon alfa-2b(intron a )
interferon-alpha
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cytarabine (ara-c) and interferon-alpha
nilotinib
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cytarabine (ara-c) and nilotinib
nilotinib(tasigna )
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cytarabine (ara-c) and nilotinib(tasigna )
vincristine.
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cytarabine (ara-c) and vincristine.
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web search results for 'cytarabine (ara-c)'?
Results
1 - 50
- cytarabine (ara-c)
Cytarabine - Wikipedia, the free encyclopedia
Cytarabine, or cytosine arabinoside, is a chemotherapy agent used mainly in the ... Sea to Ara C An essay on the history of cytarabine. [edit] References ...
http://en.wikipedia.org/wiki/Cytarabine
en.wikipedia.org
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summary
Cytarabine Official FDA information, side effects and uses.
Accurate, FDA approved Cytarabine information for healthcare ... The Cytarabine (Ara-C) Syndrome. A Cytarabine syndrome has been described by Castleberry. ...
http://www.drugs.com/pro/cytarabine.html
www.drugs.com
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summary
Cytarabine
... Cytarabine. ... cytarabine, cytosine arabinoside. Ara-C, Cytarabine-U. Cytarabine is ... Cytarabine should be used only under the supervision of a medical ...
http://www.webmd.com/cancer/cytarabine
www.webmd.com
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summary
Cytarabine (Cytarabine) Drug Information: Uses, Side Effects, Drug ...
Cytarabine for Injection USP, commonly known as ara-C, an antineoplastic for ... The Cytarabine (Ara-C) Syndrome: A cytarabine syndrome has been described by ...
http://www.rxlist.com/cytarabine-drug.htm
www.rxlist.com
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summary
Cytarabine: Drug Information Provided by Lexi-Comp: Merck Manual ...
Ara-C. Arabinosylcytosine. Cytarabine (Conventional) Cytarabine Hydrochloride. Cytosar-U ... Ara-C (AR) Arabine (DK, FI, FR) Arabitin (JP) Aracytin (CO, GR, IT, ...
http://www.merck.com/mmpe/lexicomp/cytarabine.html
www.merck.com
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Living with Cancer Chemotherapy
Cytarabine (Cytosar , ARA-C, Cytosine Arabinoside) ... Cytarabine (Cytosar,® ARA-C, Cytosine Arabinoside) Living with Cancer Chemotherapy Series ...
http://www.cc.nih.gov/ccc/patient_education/CaTxeng/cytarabine.pdf
www.cc.nih.gov
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Cytarabine - Yahoo! Health
Cytarabine is classified as an antimetabolite. It kills cancer cells by interfering with the way ... Ara-C, Cytarabine-U. Cytarabine is given intravenously. ...
http://health.yahoo.com/cancer-medications/cytarabine/healthwise--tv7457.html
health.yahoo.com
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summary
Effects of high-dose cytarabine.
... cerebrospinal fluid, and tear concentrations of cytarabine (ara-C) were measured ... Peak plasma ara-C concentrations (2.0 microM) after high-dose therapy were 50 ...
http://www.ncbi.nlm.nih.gov/pubmed/7075116
www.ncbi.nlm.nih.gov
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summary
Pharmacodynamics of cytarabine alone and in combination with 7 ...
... Chk1 in response to cytarabine (ara-C) induced an S-phase checkpoint ... The nucleoside analogue cytarabine (ara-C), an effective and widely used agent ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1895741
www.pubmedcentral.nih.gov
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MedlinePlus Drug Information: Cytarabine
Cytarabine ... A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9. Cytarabine (sye tare' a been) ... Ara-C. Cytosine arabinoside. Last Reviewed - 09/01/2008 ...
http://www.nlm.nih.gov/medlineplus/druginfo/meds/a682222.html
www.nlm.nih.gov
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summary
ChemIDPlus/HSDB 147-94-4 Toxicity - National Toxicology Program
This report indicated that Ara-C neurotoxicity, possibly aggravated in our ... punctate keratitis of both eyes following high dose cytarabine therapy (HD-Ara-C) ...
http://ntp.niehs.nih.gov/index.cfm?objectid=E87DE35F-BDB5-82F8-F77673A03DD98246
ntp.niehs.nih.gov
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summary
Cytarabine - PubChem Public Chemical Database
PubChem Compound Summary ... Cytarabine InjectionNOT FOR INTRATHECAL USE - CONTAINS ... Ara-C. Depocyt. Depocyt (TN) Cytarabine (JP15/USP/INN) D00168. 147-94-4 ...
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=7847236
pubchem.ncbi.nlm.nih.gov
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summary
Cytarabine - Wikipedia, the free encyclopedia
Cytarabine. From Wikipedia, the free encyclopedia (Redirected from Ara-C) ... Sea to Ara C An essay on the history of cytarabine. [edit] References ...
http://en.wikipedia.org/wiki/Ara-C
en.wikipedia.org
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summary
Phase I study of cladribine, cytarabine (Ara-C), granulocyte colony ...
... I study of cladribine, cytarabine (Ara-C), granulocyte colony stimulating factor ... Given the synergy in vitro between Ara-C and imatinib mesylate on AML cell ...
http://www.ncbi.nlm.nih.gov/pubmed/18571721?dopt=Abstract
www.ncbi.nlm.nih.gov
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summary
Definition of CP-4055 - National Cancer Institute Drug Dictionary
... analog cytosine arabinoside (cytarabine; Ara-C) with potential antineoplastic activity. ... also inhibits RNA synthesis, an effect not seen with cytarabine. ...
http://www.nci.nih.gov/Templates/drugdictionary.aspx?CdrID=463939
www.nci.nih.gov
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summary
Sequential multiagent chemotherapy is not superior to high-dose ...
Treatment with 7 days of cytarabine (Ara-C) and 3 days of daunorubicin has been ... was shown in CALGB study 8525 that Ara-C administered as a single agent at a ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1895015
www.pubmedcentral.nih.gov
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Organism
NIAID Home / Anti-HIV/OI Chemical Compound Search / Anti-HIV/OI ... Ara-C. Cytarabine. Tarabine. Udicil. Arabinosylcytosine. AraC. Alexan. Cytosine arabinoside ...
http://chemdb.niaid.nih.gov/struct_search/an/AN_many.asp?txt...
chemdb.niaid.nih.gov
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summary
Treatment of relapsed/refractory AIDS-related lymphomas (AIDS-NHL) with ...
... (AIDS-NHL) with high dose cytarabine (ARA-C)/cisplatin combination regimens. ... Combination high dose Ara-C/cisplatin regimens have shown activity in de ...
http://gateway.nlm.nih.gov/MeetingAbstracts/ma?f=102237726.html
gateway.nlm.nih.gov
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summary
Cytosar consumer information from Drugs.com
Other commonly used names are ara-C and cytosine arabinoside . Category. Antineoplastic ... Cytarabine (sye-TARE-a-been) belongs to the group of medicines ...
http://www.drugs.com/cons/Cytosar.html
www.drugs.com
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summary
DepoCyt (Cytarabine Liposome Injection) Drug Information: Uses, Side ...
Learn about the prescription medication DepoCyt (Cytarabine Liposome Injection), drug uses, dosage, side effects, ... Ara-C (N=28) Nervous System Disorders ...
http://www.rxlist.com/cgi/generic/depocyt.htm
www.rxlist.com
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summary
GEO Accession viewer
Cytarabine (ARA-C) was identified as the top hit in a small molecule library screen. ... A673 treated with cytarabine (ARA-C) for 24 hours with concentration ...
http://www.ncbi.nlm.nih.gov/projects/geo/query/acc.cgi?acc=GSE6930
www.ncbi.nlm.nih.gov
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summary
Treatment of acute myeloid leukemia
... received daunorubicin or idarubicin for 3 days and cytarabine (ara-C) at a dose ... and 5 (so-called high-dose ara-C, HiDAC) followed by four courses of ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2625419
www.pubmedcentral.nih.gov
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DCCPS: Cancer Control Research
... by applicant): The nucleoside analog cytarabine (ara-C) has been the mainstay of ... Ara-C is the main drug used in AML chemotherapy but the cellular ...
http://dccps.nci.nih.gov/grants/abstract.asp?ApplID=7436471
dccps.nci.nih.gov
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summary
9663763 1998 10 01 1998 10 01 2006 11 15 0142-9612 19 7-9 1998 Apr-May ...
861-9 The release of cytarabine (ara-C) from poly(2-hydroxyethyl methacrylate) ... Two ara-C loaded hydrogel discs, each with 25 mg of the drug, were ...
http://www.ncbi.nlm.nih.gov/pubmed/9663763
www.ncbi.nlm.nih.gov
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summary
Immunosuppressive Medications
Cytarabine ara-C. A. Cytarabine Cytosar-U® A. Cytarabine DepoCyt. A. Dacarbazine DTIC-Dome® ... C = Corticosteroid. D = DMARD (Disease Modifying Anti-Rheumatic ...
http://www.bt.cdc.gov/agent/smallpox/vaccination/pdf/immuno-suppress-meds.pdf
www.bt.cdc.gov
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summary
Cytarabine for progressive multifocal leucoencephalopathy (PML) in AIDS ...
... AIDS-patients (pts), but few reports demonstrated efficacy of cytarabine (Ara-C) ... of 7 AIDS-pts treated with IV and intrathecal (IT) Ara-C for PML. ...
http://gateway.nlm.nih.gov/MeetingAbstracts/ma?f=102204672.html
gateway.nlm.nih.gov
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summary
Neoplasia: Blockade of adaptive defensive changes in cholesterol uptake ...
... to idarubicin (Ida) ([12 mg/(M2 · day), days 4-6]) + high-dose cytarabine (Ara-C; ... in AML samples treated in vitro with Ara-C and/or DNR.3 In addition, we ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1852228
www.pubmedcentral.nih.gov
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Organism
Palm O-ara-C. Palmitoyl cytarabine. Palmo-Ara-C. PalmO-ara-C. PALMO-ARA-C. P-Ara-C. NSC135962. AIDS# 126993. Links to ChemID Plus by CAS# 31088-06-9 ...
http://chemdb.niaid.nih.gov/struct_search/an/AN_many.asp?txt...
chemdb.niaid.nih.gov
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summary
dryvax and Ara c Drug Interactions
dryvax and Ara c Drug Interactions. Drug-drug and drug-food ... Ara c (cytarabine) Interaction(s) found: cytarabine and smallpox vaccine (Major Drug-Drug) ...
http://www.drugs.com/drug-interactions/dryvax_d04831_ara-c_d00201.html
www.drugs.com
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summary
Living with Cancer Chemotherapy
Cytarabine (Cytosar®, ARA-C, Cytosine Arabinoside) High-Dose Cytarabine (Cytosar®, ARA-C, Cytosine Arabinoside) Dacarbazine (DTIC) ...
http://www.cc.nih.gov/ccc/patient_education/CaTxeng/cancerchemo.html
www.cc.nih.gov
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summary
Potential mechanisms of resistance to cytarabine in AML patients.
... II alpha (TOPO II) are involved in clinical resistance to cytarabine (ara ... leukemia (AML) patients treated with ara-C, including 31 for whom samples were ...
http://www.ncbi.nlm.nih.gov/pubmed/12008078
www.ncbi.nlm.nih.gov
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summary
Heat shock protein 90 inhibition sensitizes acute myelogenous leukemia ...
... ML-1 cells were treated for 24 hours with diluent or 30 nM cytarabine (Ara-C) ... with diluent or the indicated concentrations of cytarabine (Ara-C) for 4 hours. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1895127
www.pubmedcentral.nih.gov
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A pharmacokinetic study of intra-CSF administered encapsulated ...
... mL cytarabine and 0.016 microg/ml for ara-U. RESULTS: The concentration of ... and a longer duration of exposure compared with standard cytarabine (Ara-C) ...
http://www.ncbi.nlm.nih.gov/pubmed/16941075
www.ncbi.nlm.nih.gov
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summary
Immunocytochemical detection of deoxycytidine kinase in haematological ...
... 4,5 These include the classic deoxycytidine analogues cytarabine (ara-C) and ... ara-C, cytarabine. dCK, deoxycytidine kinase. NSCLC, non-small cell lung cancer ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1770710
www.pubmedcentral.nih.gov
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DepoCyt Official FDA information, side effects and uses.
... elimination of cytarabine is metabolism to the inactive compound ara-U, followed ... Ara-C (N=28) Nervous System Disorders. Headache NOS. 144 (56%) 17 (52 ...
http://www.drugs.com/pro/depocyt.html
www.drugs.com
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HyperCVAD - Wikipedia, the free encyclopedia
Cytarabine or Ara-C (Cytosar) is an antimetabolite 70mg IT Day 7 ... Foundation, Inc., a U.S. registered 501(c)(3) tax-deductible nonprofit charity. ...
http://en.wikipedia.org/wiki/HyperCVAD
en.wikipedia.org
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Definition of cytarabine - National Cancer Institute Drug Dictionary
Cytarabine is converted to the triphosphate form within the cell and then ... ARA-C. Code names: CHX-3311. U-19920. U-29920A HCl. WR-28453. Chemical structure names: ...
http://www.nci.nih.gov/Templates/drugdictionary.aspx?CdrID=39015
www.nci.nih.gov
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Randomized trial of a slow-release versus a standard formulation of ...
... that maintains cytotoxic concentrations of cytarabine (ara-C) in the CSF of most ... 50 mg once every 2 weeks or free ara-C 50 mg twice a week for 1 month. ...
http://www.ncbi.nlm.nih.gov/pubmed/10506606
www.ncbi.nlm.nih.gov
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CHALLENGES AND OPPORTUNITIES IN CLINICAL DRUG DEVELOPMENT
CYTARABINE (ARA-C) IN PATIENTS WITH PROGRESSIVE MFL ... FOR CYTARABINE (ARA-C) IV for remission induction of acute non-lymphocytic ...
http://www.cc.nih.gov/training/training/principles/slides/Dr...
www.cc.nih.gov
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summary
Remission-Induction Regimens in Acute Nonlymphocytic Leukemia
... 20 patients were treated with cytarabine (Ara-C) and 6-thioguanine (6-TG), the ... a three-day course of daunomycin (DNM) to the Ara-C and 6-TG therapy. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1272302
www.pubmedcentral.nih.gov
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19366062 2009 04 15 0300-8916 95 1 2009 Jan-Feb Tumori Protective ...
87-90 BACKGROUND: Cytarabine (ARA-C) has been used for many years in the ... ARA-C (3.6 mg) was administered intraperitoneally for 5 days to groups II, III ...
http://www.ncbi.nlm.nih.gov/pubmed/19366062
www.ncbi.nlm.nih.gov
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Antiviral Activity of Cytarabine in Herpesvirus?Infected Rats
Cytarabine (ara-C) (40 to 320 mg/kg), administered subcutaneously to inoculated ... Ara-C treatment, initiated 4 h after inoculation, caused a delay in the ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=444574
www.pubmedcentral.nih.gov
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Higher Chemo Drug Dose Prolongs Lives - Cancer Information (Cancers ...
Information on many different cancers includes symptoms, cancer detection and ... given in combination with another chemotherapy drug called ara-C (cytarabine) ...
http://www.medicinenet.com/script/main/art.asp?articlekey=94710
www.medicinenet.com
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summary
17321987 2007 02 26 2007 05 09 2007 11 15 0925-5710 85 2 2007 Feb Int ...
108-15 The combination of cytarabine (ara-C) with fludarabine is a common ... Therapy-resistant leukemia may exhibit ara-C resistance, the mechanisms of which ...
http://www.ncbi.nlm.nih.gov/pubmed/17321987
www.ncbi.nlm.nih.gov
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summary
High Dose Chemotherapy Prolongs Survival for Leukemia - National Cancer ...
Preliminary results from a large, randomized clinical trial for patients ages 16 to 60 with previously untreated acute ... 1960s, ara-C (cytarabine), had a ...
http://cancernet.nci.nih.gov/newscenter/pressreleases/AMLdau...
cancernet.nci.nih.gov
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summary
The Short and Intensive B-ALL Protocol Is a Highly Effective Regimen in ...
... (IFO), methotrexate (MTX), cytarabine (Ara-C), vincristine, and dexamethasone are ... During cycle B, Ara-C, VM26 and IFO are replaced by doxorubicine and ...
http://gateway.nlm.nih.gov/MeetingAbstracts/ma?f=102270976.html
gateway.nlm.nih.gov
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summary
Randomized use of cyclosporin A (CsA) to modulate P-glycoprotein in ...
... induction treatment (standard-dose cytarabine [Ara-C]) combined with daunomycin ... thioguanine (DAT) versus high-dose Ara-C and daunomycin and thioguanine (HDAT) ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1895393
www.pubmedcentral.nih.gov
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Administration of low-dose cytarabine results in immediate S-phase ...
... the cell-cycle kinetics of HSC after a single dose of cytarabine (Ara-C) ... Two hours after administration of Ara-C, LSK cells ceased to incorporate BrdU. ...
http://www.ncbi.nlm.nih.gov/pubmed/15676217
www.ncbi.nlm.nih.gov
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summary
A randomized study of high-dose cytarabine in induction in acute ...
High-dose cytarabine (ara-c) may overcome cytarabine resistance in leukemic blasts. ... dose cytarabine 100 mg/m2 continuous intravenous infusion for 7 days with ...
http://www.ncbi.nlm.nih.gov/pubmed/8634416
www.ncbi.nlm.nih.gov
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Chemotherapy Regimens for Paediatric ALL
12?33; cyclophosphamide (CPM) on days 36 and 64; cytarabine (ARA?C) in ... ARA?C twice on day 5; MTX and CPM every 12 ... 11; and MTX/ARA?C/PRED IT on day 1. ...
http://www.who.int/selection_medicines/committees/subcommitt...
www.who.int
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summary
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