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cyclosporin
what is 'cyclosporin'?
Definition for cyclosporin
Ciclosporin (pronounced /?sa?kl??sp?r?n/ ), cyclosporine ( USAN ) or cyclosporin (former BAN ), is an immunosuppressant drug widely used in post-allogeneic organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection .
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Ciclosporin (pronounced /?sa?kl??sp?r?n/ ), cyclosporine ( USAN ) or cyclosporin (former BAN ), is an immunosuppressant drug widely used in post-allogeneic organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection . It has been studied in transplants of skin, heart, kidney, liver, lung, pancreas, bone marrow and small intestine. Initially isolated from a Norwegian soil sample, Ciclosporin A , the main form of the drug, is a cyclic nonribosomal peptide of 11 amino acids (an undecapeptide) produced by the fungus Tolypocladium inflatum Gams , and contains D-amino acids , which are rarely encountered in nature. [ 1 ]
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search results for diagnoses treated with 'cyclosporin'
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diagnosis
urticaria
allergic skin rash
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cyclosporin and urticaria
granuloma annulare
chronic skin disease with red bumps in a ring
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cyclosporin and granuloma annulare
eosinophilic fasciitis
inflammation and thickening of skin and fascia
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cyclosporin and eosinophilic fasciitis
search results for related procedures when taking 'cyclosporin'
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procedures
Complete Blood Count
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cyclosporin and Complete Blood Count
Erythrocyte Sedimentation Rate (ESR)
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cyclosporin and Erythrocyte Sedimentation Rate (ESR)
Rheumatoid Factor (RF)
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cyclosporin and Rheumatoid Factor (RF)
Biopsy skin
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cyclosporin and Biopsy skin
Antinuclear Antibody (ANA)
Antinuclear antibody blood test used to screen for autoimmune disorders
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cyclosporin and Antinuclear Antibody (ANA)
Liver Function Tests
elevated liver enzymes
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cyclosporin and Liver Function Tests
Allergen Immunotherapy
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cyclosporin and Allergen Immunotherapy
Allergy, Skin Test
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cyclosporin and Allergy, Skin Test
Anti thyroperoxidase(anti TPO) antibody
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cyclosporin and Anti thyroperoxidase(anti TPO) antibody
Antithyroid antibodies
antibodies against thyroid tissue
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cyclosporin and Antithyroid antibodies
Avoid Allergen Exposure
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cyclosporin and Avoid Allergen Exposure
Cold agglutinin titer
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cyclosporin and Cold agglutinin titer
Complement levels
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cyclosporin and Complement levels
Complete metabolic panel
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cyclosporin and Complete metabolic panel
Diet diary
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cyclosporin and Diet diary
Discontinue medications
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cyclosporin and Discontinue medications
Elimination diet
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cyclosporin and Elimination diet
H pylori immunoglobulin G [IgG])
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cyclosporin and H pylori immunoglobulin G [IgG])
H. pylori culture
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cyclosporin and H. pylori culture
H.pylori serology
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cyclosporin and H.pylori serology
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related medication search results for 'cyclosporin'
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drugs
loratadine
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cyclosporin and loratadine
dapsone
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cyclosporin and dapsone
cimetidine
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cyclosporin and cimetidine
colchicine
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cyclosporin and colchicine
prednisone
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cyclosporin and prednisone
The following are types of physicians relevant for 'cyclosporin'.
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web search results for 'cyclosporin'?
Results
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- cyclosporin
Ciclosporin - Wikipedia, the free encyclopedia
The immuno-suppressive effect of cyclosporin was discovered on January 31, 1972, ... Cyclosporin A has been investigated as a possible neuroprotective agent in ...
http://en.wikipedia.org/wiki/Ciclosporin
en.wikipedia.org
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Cyclosporin A Drug Information, Professional
Cyclosporin A Drug Information from Drugs.com. Includes Cyclosporin A side effects, interactions and indications. ... cyclosporin A. ...
http://www.drugs.com/mmx/cyclosporin-a.html
www.drugs.com
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Cyclosporin neurotoxicity after chemotherapy
Cyclosporin causes reversible posterior leukoencephalopathy syndrome. Authors' reply ... Cyclosporin neurotoxicity is often associated with mild to moderate ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1116154
www.pubmedcentral.nih.gov
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Cyclosporin A CAS No. 59865-13-3
Cyclosporin A is known to be a human carcinogen based on studies in ... Some of these patients were treated with cyclosporin A ...
http://ntp-server.niehs.nih.gov/ntp/roc/eleventh/profiles/s053cycl.pdf
ntp-server.niehs.nih.gov
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Cyclosporin A specifically inhibits function of nu...[Science. 1989 ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and other life science journals for biomedical ...
http://www.ncbi.nlm.nih.gov/pubmed/2595372?dopt=Abstract
www.ncbi.nlm.nih.gov
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Side Effects - Cyclosporin
A list of the side effects of Cyclosporin (also called Cyclosporin-A), a medication that is used in the treatment of Inflammatory Bowel Disease.
http://ibdcrohns.about.com/cs/prescriptiondrugs/p/medcyclosporin.htm
ibdcrohns.about.com
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Cyclosporin A Reverses Chemoresistance in Patients With Gynecologic ...
Cyclosporin A is well tolerated and has significant potential for reversal of ... Cyclosporin A has also been shown to reverse resistance to cisplatin unrelated ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1508129
www.pubmedcentral.nih.gov
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Complete Cyclosporine (Cyclosporin A) information from Drugs.com
All about Cyclosporine (Cyclosporin A). View complete and up to date Cyclosporine (Cyclosporin A) information - part of the Drugs.com trusted medication database.
http://www.drugs.com/ppa/cyclosporine-cyclosporin-a.html
www.drugs.com
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Systemic cyclosporin A in high failure risk, repeated corneal ...
Cyclosporin A is a T cell mediated immunosuppressant drug that has been ... The effect of cyclosporin A on high rejection risk corneal transplants has not ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1771260
www.pubmedcentral.nih.gov
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New Drug Cyclosporin Hailed for Treating Psoriasis on RxList
Learn more about the new drug Cyclosporin and how it is being used to treat plaque psoriasis. ... Cyclosporin, a type of drug called a calcineurin inhibitor, ...
http://www.rxlist.com/script/main/art.asp?articlekey=88935
www.rxlist.com
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Diltiazem co-treatment in renal transplant patients receiving ...
Furthermore, cyclosporin has complex pharmacokinetics and pharmacodynamics, such ... Some of cyclosporin's numerous metabolites are believed to be active, though to ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1884301
www.pubmedcentral.nih.gov
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The influence of cyclosporin A on cell-mediated immunity.
Britton S, Palacios R. Cyclosporin A--usefulness, risks and mechanism of action. ... Effect of cyclosporin and interleukin-2 on the restoration of in vitro immune ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1541682
www.pubmedcentral.nih.gov
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Cyclosporin A: a powerful immunosuppressant.
In vitro effects of cyclosporin A on lymphocyte subpopulations. ... Cyclosporin A, a powerful immunosuppressant in vivo and in vitro in the dog, ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1863293
www.pubmedcentral.nih.gov
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summary
The immunosuppressive drugs cyclosporin A and tacrolimus inhibit ...
In a mammalian two-hybrid assay, cyclosporin A did not inhibit Ser119-dependent ... Besides NFAT, cyclosporin A and tacrolimus also inhibit the calcineurin ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1576078
www.pubmedcentral.nih.gov
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Lack of effect of spiramycin on cyclosporin pharmacokinetics.
The plasma concentrations of cyclosporin were measured both by non-specific ... Therefore, the pharmacokinetics of cyclosporin (parent drug and parent drug plus ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1379806
www.pubmedcentral.nih.gov
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Cyclosporine Drops facts and comparsions at Drugs.com
All about Cyclosporine Drops. View complete and up to date Cyclosporine Drops information - part of the Drugs.com trusted medication database.
http://www.drugs.com/cdi/cyclosporine-drops.html
www.drugs.com
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Cyclosporin and renal graft histology.
Patients receiving cyclosporin were converted to azathioprine and prednisolone ... changes in rats receiving cyclosporin A at immunotherapeutic dosage for ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=499668
www.pubmedcentral.nih.gov
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Drug points: Cyclosporin neurotoxicity after chemotherapy
Cyclosporin neurotoxicity may result from interaction with chemotherapy used for ... His cyclosporin concentration was 250?g/l and his methotrexate concentration was ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=27845
www.pubmedcentral.nih.gov
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Drug points: Possible interaction between clindamycin and cyclosporin
Cyclosporin is extensively metabolised by the liver. Therefore, circulating cyclosporin concentrations may be influenced by drugs ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=59109
www.pubmedcentral.nih.gov
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summary
Protective effects of Cyclosporin-A in splanchnic artery occlusion shock
Cyclosporin A (CsA) is an immunosuppressant drug that inhibits nitric oxide (NO) ... Administration of cyclosporin A or 1400W improved the impaired contractile ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1572071
www.pubmedcentral.nih.gov
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Tacrolimus versus cyclosporin for immunosuppression in renal ...
Cyclosporin is currently the most widely used and important immunosuppressive ... Figures are given for tacrolimus/cyclosporin where appropriate ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=27842
www.pubmedcentral.nih.gov
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Cyclophilin-dependent stimulation of transcription by cyclosporin A.
Cyclosporin A specifically inhibits function of nuclear proteins involved in T cell activation. ... common target of cyclophilin-cyclosporin A and FKBP-FK506 ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=45617
www.pubmedcentral.nih.gov
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Cyclosporin-mediated inhibition of bovine calcineurin by cyclophilins A ...
Cyclosporin A inhibits T-cell growth factor gene expression at the level of mRNA ... FK-506 and cyclosporin A inhibit highly similar signal transduction pathways in ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=525566
www.pubmedcentral.nih.gov
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Blood cyclosporin concentrations and renal allograft dysfunction.
Mean predose blood cyclosporin concentrations measured by radioimmunoassay ... Cyclosporin measurements made at the time of biopsy and reference to the highest ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1341913
www.pubmedcentral.nih.gov
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Effects of cyclosporin on collagen induced arthritis in mice.
Cyclosporin, when given prophylactically, was capable of suppressing the ... Furthermore, treatment with cyclosporin, started on the same day as the booster ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1001880
www.pubmedcentral.nih.gov
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Cyclosporin A reduces canalicular membrane fluidity and regulates ...
The immunosuppressant cyclosporin A is known to cause intrahepatic cholestasis. ... Cyclosporin A reduced biliary lipid secretion along with a disproportionate ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1221690
www.pubmedcentral.nih.gov
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A single institution, randomized, prospective trial of cyclosporin ...
A reduction in cyclosporin dose because of nephrotoxicity was required in 96 of ... Effect of cyclosporin A on human lymphocyte responses in vitro. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=3882063
www.pubmedcentral.nih.gov
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Topical cyclosporin stimulates neovascularization in resolving sterile ...
The patients were ultimately treated with topical cyclosporin. ... Treatment with topical cyclosporin alone may be considered in patients with ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1298214
www.pubmedcentral.nih.gov
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Effect of cyclosporin A on murine natural killer cells.
In mice, cyclosporin A decreased the natural killer cell-enhancing effect of two ... Effect of cyclosporin A on human lymphocyte responses in vitro. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=551447
www.pubmedcentral.nih.gov
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Effect of cyclosporin A on the allergen-induced late asthmatic reaction
Cyclosporin A has efficacy in chronic severe corticosteroid-dependent asthma and ... It was therefore hypothesised that cyclosporin A would attenuate both the EAR ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1758561
www.pubmedcentral.nih.gov
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Cyclosporin in the treatment of severe chronic idiopathic uveitis.
In 14 patients this was combined with cyclosporin in a single daily dose of 10 ... Cyclosporin A, a powerful immunosuppressant in vivo and in vitro in the dog, ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1042124
www.pubmedcentral.nih.gov
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Clinically significant drug interactions with cycl...[Clin ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... Cyclosporin: an updated review of ...
http://www.ncbi.nlm.nih.gov/pubmed/8906896
www.ncbi.nlm.nih.gov
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Testing Status: Transgenic LEP (Cyclosporin A) M970003 - National ...
Related: TRANSGENIC MODEL EVALUATION (CYCLOSPORIN A) Formula: C62 H111 N11 O12 ... CYCLOSPORIN A (TRANSGENIC LEP) Known Uses: PHARMACEUTICAL. ...
http://ntp.niehs.nih.gov/index.cfm?objectid=BDBEE3AC-123F-79...
ntp.niehs.nih.gov
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Evidence for a functional receptor for cyclosporin A on the surface of ...
Cyclosporin A (CsA) is an immunosuppressive agent that inhibits the synthesis of ... The actions of cyclosporin A and FK506 suggest a novel step in the activation of ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=49080
www.pubmedcentral.nih.gov
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Calcineurin Regulates Cyclin D1 Accumulation in Growth-stimulated ...
In multiple cell types, cyclosporin A causes a G1 cell cycle arrest, implicating ... Although cyclosporin A reduced the levels of cyclin D1 mRNA in pancreatic acinar ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=379279
www.pubmedcentral.nih.gov
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Effect of cyclosporin A on lymphocyte activation by the calcium ...
Cyclosporin A and dexamethasone suppress T cell responses by selectively acting ... Cyclosporin A inhibits lymphokine production but not the responses of ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1454254
www.pubmedcentral.nih.gov
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Long term efficacy and safety of cyclosporin versus parenteral gold in ...
Influence of cyclosporin A on radiological progression in early rheumatoid ... H. Renal toxicity of long-term cyclosporin. Scand J Rheumatol. 1999;28(2):65 ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1754124
www.pubmedcentral.nih.gov
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Cyclosporin A inhibits CD40 ligand expression in T lymphocytes.
Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. ... Cyclosporin A inhibits T-cell growth factor gene expression at the ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=294093
www.pubmedcentral.nih.gov
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Cyclosporin A inhibits acute serum sickness nephritis in rabbits.
The effect of the immunosuppressive agent cyclosporin A (Cy A) on the renal ... Cyclosporin A and dexamethasone suppress T cell responses by selectively acting ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1536029
www.pubmedcentral.nih.gov
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Cyclosporin therapy in Mooren's ulcer.
Systemic cyclosporin (10 mg/kg/day) resulted in resolution of the corneal ... Cyclosporin side effects included hirsutism, hypertension, increased blood ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1041189
www.pubmedcentral.nih.gov
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Drug points: Probable interaction between cyclosporin A and low dose ...
The dose of cyclosporin A was changed several times during the three year follow ... Monitoring of cyclosporin A concentration in whole blood by an enzyme multiplied ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=27344
www.pubmedcentral.nih.gov
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Cyclosporin A (CyA) in primary Sjögren's syndrome: a double blind study.
The efficacy and toxicity of cyclosporin A (CyA) were studied in a blind fashion ... Cyclosporin A therapy in the treatment of intraocular inflammatory disease ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1001978
www.pubmedcentral.nih.gov
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Drug points: Fever associated with cyclosporin for treating atopic ...
Cyclosporin is a fungal metabolite widely used in preventing graft rejection ... She was admitted to monitor her response to cyclosporin. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?&artid=28712
www.pubmedcentral.nih.gov
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Immunosuppression with cyclosporin A alters the thymic microenvironment.
The effect of cyclosporin A (CyA) immunosuppression on the murine thymic ... Inhibition of drug-induced eosinophilia by cyclosporin A. Scand J Immunol. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1534650
www.pubmedcentral.nih.gov
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Effect of cyclosporin A treatment on the production of antibody in ...
Metabolic and immunological effects of cyclosporin in recently diagnosed type 1 ... Cyclosporin prophylaxis induces long-term prevention of diabetes, and inhibits ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=442429
www.pubmedcentral.nih.gov
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Cyclosporin in the treatment of corticosteroid resistant autoimmune ...
Remission was again attained by returning the dose of cyclosporin to 5 mg/kg/day. ... Cyclosporin seems to have a role in the treatment of corticosteroid resistant ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1382466
www.pubmedcentral.nih.gov
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Vascular mechanisms of cyclosporin-induced hypertension in the rat.
Mechanism of cyclosporin potentiation of vasoconstriction of the isolated rat ... Cyclosporin A inhibits endothelium-dependent, prostanoid-induced relaxation in ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=294377
www.pubmedcentral.nih.gov
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Suppression of delayed-type hypersensitivity reactions and lymphokine ...
The effect of cyclosporin A on the adoptive transfer of experimental allergic ... Britton S, Palacios R. Cyclosporin A--usefulness, risks and mechanism of action. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1536020
www.pubmedcentral.nih.gov
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Monitoring cyclosporin treatment.
Cyclosporin." in volume 305 on page 1491. Full text ... Dougados M, Amor B. Cyclosporin A in rheumatoid arthritis: preliminary clinical ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1676448
www.pubmedcentral.nih.gov
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Inhibition of human immunodeficiency virus replication by ...
Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. ... Cyclosporin A specifically inhibits function of nuclear proteins ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=41698
www.pubmedcentral.nih.gov
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