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ciclosporin
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what is 'ciclosporin'?
Definition for ciclosporin
Ciclosporin (pronounced /?sa?kl??sp?r?n/ ), cyclosporine ( USAN ) or cyclosporin (former BAN ), is an immunosuppressant drug widely used in post-allogeneic organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection .
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Ciclosporin (pronounced /?sa?kl??sp?r?n/ ), cyclosporine ( USAN ) or cyclosporin (former BAN ), is an immunosuppressant drug widely used in post-allogeneic organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection . It has been studied in transplants of skin, heart, kidney, liver, lung, pancreas, bone marrow and small intestine. Initially isolated from a Norwegian soil sample, Ciclosporin A , the main form of the drug, is a cyclic nonribosomal peptide of 11 amino acids (an undecapeptide) produced by the fungus Tolypocladium inflatum Gams , and contains D-amino acids , which are rarely encountered in nature. [ 1 ]
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diagnoses treated with 'ciclosporin'
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1
diagnosis
panniculitis
inflammation of fat under the skin and in deeper tissues
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ciclosporin and panniculitis
related procedures when taking 'ciclosporin'
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57
procedures
24 hour urine calcium
the amount of calcium that is excreted from the body
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ciclosporin and 24 hour urine calcium
Activated partial thromboplastin time
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ciclosporin and Activated partial thromboplastin time
Anti La (SSB) antibody
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ciclosporin and Anti La (SSB) antibody
Anti double stranded DNA antibodies
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ciclosporin and Anti double stranded DNA antibodies
Anti-Jo-1 antibody
antibodies seen in certain muscle and lung diseases
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ciclosporin and Anti-Jo-1 antibody
Anti-Mi-1 antibody
antibodies found in various collagen vascular diseases
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ciclosporin and Anti-Mi-1 antibody
Anti-Ro (SS-A) antibodies
antibodies against certain collagen vascular diseases
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ciclosporin and Anti-Ro (SS-A) antibodies
Antinuclear Antibody (ANA)
Antinuclear antibody blood test used to screen for autoimmune disorders
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ciclosporin and Antinuclear Antibody (ANA)
Arterial Blood Gas
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ciclosporin and Arterial Blood Gas
B cell count
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ciclosporin and B cell count
B cell function
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ciclosporin and B cell function
BUN
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ciclosporin and BUN
Biopsy skin
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ciclosporin and Biopsy skin
Blood culture
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ciclosporin and Blood culture
Blood, Platelet Count
Platelet Count
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ciclosporin and Blood, Platelet Count
Bone Marrow Aspiration
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ciclosporin and Bone Marrow Aspiration
CT chest
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ciclosporin and CT chest
CT muscle
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ciclosporin and CT muscle
CT scan
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ciclosporin and CT scan
Chest X-ray
Radiological technique to image the chest
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ciclosporin and Chest X-ray
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related medication for 'ciclosporin'
1 - 5 of
9
drugs
aspirin
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ciclosporin and aspirin
diclofenac
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ciclosporin and diclofenac
etoposide
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ciclosporin and etoposide
hydroxychloroquine
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ciclosporin and hydroxychloroquine
ibuprofen
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ciclosporin and ibuprofen
ivig
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ciclosporin and ivig
potassium iodide
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ciclosporin and potassium iodide
prednisone
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ciclosporin and prednisone
tetracycline
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ciclosporin and tetracycline
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The following are types of physicians relevant for 'ciclosporin'.
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web search results for 'ciclosporin'?
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- ciclosporin
Ciclosporin - Wikipedia, the free encyclopedia
Ciclosporin (pronounced /?sa?kl??sp?r?n/), cyclosporine (USAN) or cyclosporin ... Retrieved from "http://en.wikipedia.org/wiki/Ciclosporin" ...
http://en.wikipedia.org/wiki/Ciclosporin
en.wikipedia.org
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summary
A comparison of the effect of ciclosporin and sirolimus on the ...
In contrast to tacrolimus, ciclosporin is an inhibitor of the multidrug ... Dosing of sirolimus and ciclosporin was based on whole-blood concentration, with ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1885150
www.pubmedcentral.nih.gov
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summary
Low-dose oral microemulsion ciclosporin for severe...[Aliment Pharmacol ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and other life science journals for biomedical ...
http://www.ncbi.nlm.nih.gov/pubmed/16091057
www.ncbi.nlm.nih.gov
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summary
Pharmaceutical Drugs - WHO - OMS -
... identified two of the drugs - ciclosporin and thiotepa - as human carcinogens. Ciclosporin, an immunosuppressant, is widely used in the prevention and ...
http://www.who.int/bookorders/anglais/detart1.jsp?sesslan=1&...
www.who.int
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summary
Talk:Ciclosporin - Wikipedia, the free encyclopedia
Ciclosporin is within the scope of WikiProject Chemicals, a daughter project of ... Retrieved from "http://en.wikipedia.org/wiki/Talk:Ciclosporin" ...
http://en.wikipedia.org/wiki/Talk:Ciclosporin
en.wikipedia.org
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summary
Benefit-risk assessment of ciclosporin withdrawal in renal transplant ...
Ciclosporin is associated with significant toxicity, including nephrotoxicity, ... Many attempts have been made to wean patients from ciclosporin. ...
http://www.ncbi.nlm.nih.gov/pubmed/16157765?cmd=Retrieve&db=...
www.ncbi.nlm.nih.gov
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summary
Drug points: Erythromelalgia induced by possible calcium channel ...
Ciclosporin, a calcineurin antagonist, acts by inhibiting calcium-calmodulin ... In this way, ciclosporin has also been observed to potentiate the peripheral ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=153834
www.pubmedcentral.nih.gov
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summary
Tacrolimus and steroids versus ciclosporin microemulsion, steroids, and ...
... is more efficacious than ciclosporin microemulsion in the prevention of acute rejection. ... and 17 months (9-54) in the ciclosporin microemulsion group. ...
http://www.ncbi.nlm.nih.gov/pubmed/15380964
www.ncbi.nlm.nih.gov
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summary
Nephrotoxicity - Wikipedia, the free encyclopedia
There are various forms of toxicity. ... diclofenac), ACE inhibitors, ciclosporin, lithium salts, cyclophosphamide, amphotericin B ...
http://en.wikipedia.org/wiki/Nephrotoxicity
en.wikipedia.org
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summary
Interleukin-2 receptor monoclonal antibodies in renal transplantation ...
... 15 Two studies gave both ciclosporin dose and target concentrations,9,16 two studies defined target ciclosporin concentrations,10,11 and three ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=153097
www.pubmedcentral.nih.gov
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summary
Effectiveness and safety of ciclosporin as therapy for autoimmune ...
Ciclosporin is a promising treatment for all of these diseases. ... Indications for ciclosporin were treatment failure (four patients) and ...
http://www.ncbi.nlm.nih.gov/pubmed/14723612
www.ncbi.nlm.nih.gov
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summary
Appraisal Consultation Document: Immunosuppressive therapy for renal ...
Suggested ciclosporin trough concentration ranges for the first 2 to 3 months ... Ciclosporin should be progressively discontinued over 4 to 8 weeks and the ...
http://www.nice.org.uk/article.asp?a=89335
www.nice.org.uk
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summary
Organism
Ciclosporin. Ramihyphin A. Cyclosporin A. Neoplanta. Sang-35. CSA. CsA. NSC290193. AIDS# 000146 ... [MeIle]4-Ciclosporin. NIM 811. AIDS# 006796. Links to ChemID ...
http://chemdb2.niaid.nih.gov/struct_search/class/class_many....
chemdb2.niaid.nih.gov
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summary
Tolypocladium inflatum - Wikipedia, the free encyclopedia
... Norwegian soil that, in certain conditions, produces Ciclosporin (Cyclosporine). The fungus from which ciclosporin was first isolated was originally ...
http://en.wikipedia.org/wiki/Tolypocladium_inflatum_Gams
en.wikipedia.org
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summary
Pharmacokinetic modelling of the interaction between St John's wort and ...
... the blood concentration of ciclosporin A (CsA), which may ... Keywords: ciclosporin A, dosage, drug interaction, pharmacokinetic model, St John's wort ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1885115
www.pubmedcentral.nih.gov
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summary
Cholestasis in pregnancy associated with ciclosporin therapy in renal ...
... in pregnancy associated with ciclosporin therapy in renal transplant ... Ciclosporin, at therapeutic concentrations, inhibits bile salt excretion pump ...
http://www.ncbi.nlm.nih.gov/pubmed/17081234
www.ncbi.nlm.nih.gov
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summary
FKBP - Wikipedia, the free encyclopedia
... over a related treatment, the drug ciclosporin, which binds cyclophilin. ... tacrolimus complex and the ciclosporin-cyclophilin complex inhibit a phosphatase ...
http://en.wikipedia.org/wiki/FKBP
en.wikipedia.org
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summary
Topical ciclosporin in the treatment of ocular surface disorders.
Ciclosporin A is an immunomodulator that specifically inhibits T lymphocyte proliferation. ... Given the increasing use of ciclosporin eye drops, the goal of ...
http://www.ncbi.nlm.nih.gov/pubmed/16170133
www.ncbi.nlm.nih.gov
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summary
Serotonin syndrome in a renal transplant patient
... azathioprine 125 mg daily, ciclosporin 100 mg twice daily, ... Secondly, in mice ciclosporin enhances brain serotoninergic neural activity with ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1279917
www.pubmedcentral.nih.gov
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summary
CYA - Wikipedia, the free encyclopedia
the California Youth Authority, renamed California Division of Juvenile Justice in 2004 ... Ciclosporin - an immuno-suppression drug ...
http://en.wikipedia.org/wiki/CYA
en.wikipedia.org
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summary
Final Appraisal Determination: Immunosuppressive therapy for renal ...
Tacrolimus is an alternative to ciclosporin when a calcineurin inhibitor is ... The initial choice of tacrolimus or ciclosporin should be ...
http://www.nice.org.uk/nicemedia/pdf/FAD_Immunosuppressive_t...
www.nice.org.uk
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summary
Long-term results of low-dose intravenous ciclospo...[Aliment Pharmacol ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... without oral ciclosporin in the long ...
http://www.ncbi.nlm.nih.gov/pubmed/12895214
www.ncbi.nlm.nih.gov
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Norman Shumway - Wikipedia, the free encyclopedia
This article concerns the American heart surgeon. ... Organ transplant Ciclosporin. Norman Edward Shumway (February 9, 1923 ? February 10, 2006) was a pioneer of ...
http://en.wikipedia.org/wiki/Norman_Shumway
en.wikipedia.org
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summary
Multi-drug resistance gene-1 (MDR-1) haplotypes an...[Clin Transplant ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from ... Ciclosporin is a substrate for P-gp and is ...
http://www.ncbi.nlm.nih.gov/pubmed/17425754
www.ncbi.nlm.nih.gov
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summary
Grapefruit juice - Wikipedia, the free encyclopedia
Main article: List of drugs affected by grapefruit ... affected include midazolam, ciclosporin, lovastatin, methadone, dextromethorphan, ...
http://en.wikipedia.org/wiki/Grapefruit_juice
en.wikipedia.org
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Clinical and cost-effectiveness of newer immunosuppressive regimens in ...
... month/1-year incidence of biopsy-proven acute rejection compared to ciclosporin. ... benefit of tacrolimus over ciclosporin appeared to be equivalent for ...
http://www.ncbi.nlm.nih.gov/pubmed/15899149
www.ncbi.nlm.nih.gov
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List of drugs: Ci - Wikipedia, the free encyclopedia
Cicloral (Hexal Australia) [Au], also known as ciclosporin. ciclosidomine (INN) ciclosporin (INN) ciclotizolam (INN) ciclotropium bromide (INN) cicloxilic acid (INN) ...
http://en.wikipedia.org/wiki/List_of_drugs:_Ci
en.wikipedia.org
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Perforin granule release from cytotoxic lymphocyte...[Skin Pharmacol ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 ... Ciclosporin, in contrast, was found to inhibit perforin-granule release ...
http://www.ncbi.nlm.nih.gov/pubmed/11586066
www.ncbi.nlm.nih.gov
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summary
Ulcerative colitis (acute exacerbations) - infliximab: appraisal ...
The two studies investigating ciclosporin differed from each other in the ... In one study, ciclosporin was compared with placebo in people with acute severe ...
http://www.nice.org.uk/guidance/index.jsp?action=article&o=41570
www.nice.org.uk
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summary
Acute graft-versus-host disease in thalassaemic marrow transplantation ...
ciclosporin (Sandimmune) 5 mg/kg, delivered intravenously 2 days prior to until ... trial of ciclosporin versus methotrexate for prophylaxis of graft-versus ...
http://www.emro.who.int/publications/emhj/0503/05.htm
www.emro.who.int
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Immunosuppression - Wikipedia, the free encyclopedia
Immunosuppression involves an act that reduces the activation or efficacy of the ... Deliberately induced immunosuppression is generally done to prevent the body ...
http://en.wikipedia.org/wiki/Immunosuppression
en.wikipedia.org
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The clinical effectiveness and cost-effectiveness of treatments for ...
Ciclosporin statistically significantly increased the number of children with ... than 6 pounds, while a course of ciclosporin cost almost 900 pounds per year. ...
http://www.ncbi.nlm.nih.gov/pubmed/17537341
www.ncbi.nlm.nih.gov
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Appraisal Consultation Document: Renal transplantation ...
The initial choice of tacrolimus or ciclosporin should be based on the relative ... In patients for whom ciclosporin withdrawal is either unsuccessful or cannot be ...
http://www.nice.org.uk/guidance/index.jsp?action=article&o=33292
www.nice.org.uk
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summary
Sympathetic ophthalmia - Wikipedia, the free encyclopedia
It can leave the patient completely blind. Symptoms may develop from days to ... be candidates for therapy with chlorambucil, cyclophosphamide, or ciclosporin. ...
http://en.wikipedia.org/wiki/Sympathetic_ophthalmia
en.wikipedia.org
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Prevention of abortion by ciclosporin treatment of fulminant ulcerative ...
Prevention of abortion by ciclosporin treatment of fulminant ulcerative colitis ... Angelberger S, Reinisch W, Dejaco C. Publication Types: Case Reports ...
http://www.ncbi.nlm.nih.gov/pubmed/16905706
www.ncbi.nlm.nih.gov
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summary
Protocol for the combined immunosuppression & radiotherapy in thyroid ...
... hypertension and hypercholesterolaemia) associated with ciclosporin. ... Hence, azathioprine has safety, tolerability and cost advantages over ciclosporin. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2275219
www.pubmedcentral.nih.gov
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Cyclophilin - Wikipedia, the free encyclopedia
Ribbon diagram of cyclophilin A in complex with ciclosporin (yellow). From PDB 1CWA. ... Cyclophilins, abbreviated Cyp (not to be confused with CYP, which is the ...
http://en.wikipedia.org/wiki/Cyclophilin
en.wikipedia.org
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summary
Primary immunosuppression with tacrolimus after li...[Int ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from ... 60) using ciclosporin A, steroids, ...
http://www.ncbi.nlm.nih.gov/pubmed/15589470
www.ncbi.nlm.nih.gov
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www.who.int/medicines/services/inn/Prestem_March08_WEB.pdf
ciclosporin derivatives -codar. see. dar -cridar. see dar. dar. drugs used in multidrug ... ciclosporin D derivatives -depsin. depsipeptide derivatives -domide ...
http://www.who.int/medicines/services/inn/Prestem_March08_WEB.pdf
www.who.int
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summary
ATC code L04 - Wikipedia, the free encyclopedia
L04AA01 Ciclosporin. L04AA02 Muromonab-CD3. L04AA03 ... FKBP/Cyclophilin/Calcineurin: Tacrolimus · Ciclosporin · Pimecrolimus. Abetimus · Gusperimus ...
http://en.wikipedia.org/wiki/ATC_code_L04
en.wikipedia.org
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Severe ulcerative colitis: present medical treatment strategies.
Therefore, intravenous ciclosporin has been proposed as a rescue therapy, with a ... with a risk of toxicity and intravenous ciclosporin is not easy to use in non ...
http://www.ncbi.nlm.nih.gov/pubmed/18220494
www.ncbi.nlm.nih.gov
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summary
Trimethoprim?sulphamethoxazole does not affect the pharmacokinetics of ...
Compared with ciclosporin, sirolimus has shown similar efficacy, but appears to ... treatment with ciclosporin and sulphamethoxazole?trimethoprim and was observed ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1884939
www.pubmedcentral.nih.gov
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Mycophenolate mofetil versus azathioprine for prev...[Lancet. 2004 Aug ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... of ciclosporin and steroid. ...
http://www.ncbi.nlm.nih.gov/pubmed/15302193?dopt=Abstract
www.ncbi.nlm.nih.gov
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List of drugs: Re - Wikipedia, the free encyclopedia
This page was last modified on 13 July 2008, at 10:12. All text is available under the terms of the GNU Free Documentation License. ...
http://en.wikipedia.org/wiki/List_of_drugs:_Re
en.wikipedia.org
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List of drugs: S-Sd - Wikipedia, the free encyclopedia
This page was last modified on 16 August 2008, at 01:55. All text is available under the terms of the GNU Free Documentation License. ...
http://en.wikipedia.org/wiki/List_of_drugs:_S-Sd
en.wikipedia.org
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Cost-effectiveness of pharmacotherapy for autoimmune hepatitis.
... therapy in the form of ciclosporin, tacrolimus or mycophenolate mofetil may be warranted. ... such as ciclosporin, tacrolimus or mycophenolate mofetil be ...
http://www.ncbi.nlm.nih.gov/pubmed/16433580
www.ncbi.nlm.nih.gov
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summary
Pyoderma gangrenosum ? a review
Ciclosporin A is an inhibitor of T-lymphocyte activation. Immunosuppressive therapy with ciclosporin A has become an accepted treatment ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1857704
www.pubmedcentral.nih.gov
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summary
List of drugs: Nb-Nh - Wikipedia, the free encyclopedia
This page was last modified on 3 November 2006, at 02:08. All text is available under the terms of the GNU Free Documentation License. ...
http://en.wikipedia.org/wiki/List_of_drugs:_Nb-Nh
en.wikipedia.org
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www.who.int/medicines/services/inn/5-Prestem_POSTMeeting_Nov07.pdf
ciclosporin derivatives -cridar. see. dar. dar. drugs used in multidrug resistance -cri ... ciclosporin. D. derivatives -depsin. depsipeptide derivatives -domide ...
http://www.who.int/medicines/services/inn/5-Prestem_POSTMeeting_Nov07.pdf
www.who.int
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Management of acute severe colitis.
The decision to use ciclosporin or infliximab for those with a poor response to ... Ciclosporin has delayed the need for urgent colectomy in many patients, but long ...
http://www.ncbi.nlm.nih.gov/pubmed/16847166
www.ncbi.nlm.nih.gov
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