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chlorambucil
what is 'chlorambucil'?
Definition for chlorambucil
Chlorambucil (marketed as Leukeran by GlaxoSmithKline ) is a chemotherapy drug that has been mainly used in the treatment of chronic lymphocytic leukemia . It is a nitrogen mustard alkylating agent and can be given orally.
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Chlorambucil (marketed as Leukeran by GlaxoSmithKline ) is a chemotherapy drug that has been mainly used in the treatment of chronic lymphocytic leukemia . It is a nitrogen mustard alkylating agent and can be given orally.
In the past, chlorambucil has been used for treating some types of non-Hodgkin lymphoma , Waldenström macroglobulinemia , polycythemia vera , trophoblastic neoplasms , and ovarian carcinoma . It also has been used as an immunosuppressive drug for various autoimmune and inflammatory conditions, such as nephrotic syndrome . Its current use is mainly in chronic lymphocytic leukemia, as it is well tolerated by most patients, though chlorambucil has been largely replaced by fludarabine as first-line treatment in younger patients. [ 1 ]
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search results for diagnoses treated with 'chlorambucil'
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19
diagnosis
chronic lymphocytic leukemia
cancer of white blood cells
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chlorambucil and chronic lymphocytic leukemia
dysgerminoma
rare ovarian tumor
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chlorambucil and dysgerminoma
granuloma annulare
chronic skin disease with red bumps in a ring
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chlorambucil and granuloma annulare
metastases
spread of malignant tumors to other body sites
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chlorambucil and metastases
nephrotic syndrome
kidney disease causing protein loss
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chlorambucil and nephrotic syndrome
pyoderma gangrenosum
swelling and ulcers on legs
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chlorambucil and pyoderma gangrenosum
Sezary's Syndrome
leukemic variant of T cell lymphoma in skin
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chlorambucil and Sezary's Syndrome
malignancy
cancer
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chlorambucil and malignancy
acute febrile neutrophilic dermatosis
acute skin disease
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chlorambucil and acute febrile neutrophilic dermatosis
hypereosinophilic syndrome
multisystem disease from increase in a type of white blood cell
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chlorambucil and hypereosinophilic syndrome
necrobiotic xanthogranuloma
chronic skin disease in middle aged or elderly people
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chlorambucil and necrobiotic xanthogranuloma
uveomeningitis syndrome
multisystem disorder affecting eye
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chlorambucil and uveomeningitis syndrome
Behcet's disease
immune system disease affecting blooe vessels
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chlorambucil and Behcet's disease
Non-Hodgkin's lymphoma
cancer of lymphocytes
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chlorambucil and Non-Hodgkin's lymphoma
minimal change glomerulonephritis
type of type of chronic kidney disease causing nephrotic syndrome
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chlorambucil and minimal change glomerulonephritis
membranous glomerulonephritis
type of chronic kidney disease with inflammation of internal kidney structures
web search for:
chlorambucil and membranous glomerulonephritis
Churg-Strauss Syndrome
autoimmune inflammation of small and medium sized blood vessels
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chlorambucil and Churg-Strauss Syndrome
Waldenstrom's macroglobulinemia
malignant disorder of lymphocytes
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chlorambucil and Waldenstrom's macroglobulinemia
cryoglobulinemia
increased globulins in blood that gel on cold exposure
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chlorambucil and cryoglobulinemia
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search results for related procedures when taking 'chlorambucil'
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195
procedures
Complete Blood Count
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chlorambucil and Complete Blood Count
serum electrolytes
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chlorambucil and serum electrolytes
Chest X-ray
Radiological technique to image the chest
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chlorambucil and Chest X-ray
BUN
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chlorambucil and BUN
Serum Creatinine
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chlorambucil and Serum Creatinine
Biopsy skin
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chlorambucil and Biopsy skin
Abdominal CAT Scan
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chlorambucil and Abdominal CAT Scan
serum immunoglobulins
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chlorambucil and serum immunoglobulins
Complete metabolic panel
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chlorambucil and Complete metabolic panel
Erythrocyte Sedimentation Rate (ESR)
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chlorambucil and Erythrocyte Sedimentation Rate (ESR)
Urinalysis
Examination of urine to detect disease
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chlorambucil and Urinalysis
Liver Function Tests
elevated liver enzymes
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chlorambucil and Liver Function Tests
Radiation Therapy
Use of ionizing radiation or xrays for medical imaging or to treat cancer
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chlorambucil and Radiation Therapy
Biopsy
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chlorambucil and Biopsy
Flow Cytometry
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chlorambucil and Flow Cytometry
Lymph node biopsy
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chlorambucil and Lymph node biopsy
Ultrasound lymph node
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chlorambucil and Ultrasound lymph node
CT chest
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chlorambucil and CT chest
CT scan
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chlorambucil and CT scan
CT Pelvis
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related medication search results for 'chlorambucil'
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98
drugs
cyclophosphamide
web search for:
chlorambucil and cyclophosphamide
prednisone
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chlorambucil and prednisone
vincristine
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chlorambucil and vincristine
alemtuzumab
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chlorambucil and alemtuzumab
cyclosporine
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chlorambucil and cyclosporine
methotrexate
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chlorambucil and methotrexate
dapsone
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chlorambucil and dapsone
rituximab
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chlorambucil and rituximab
doxorubicin
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chlorambucil and doxorubicin
fludarabine
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chlorambucil and fludarabine
thalidomide
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chlorambucil and thalidomide
mycophenolate mofetil
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chlorambucil and mycophenolate mofetil
tacrolimus
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chlorambucil and tacrolimus
bleomycin
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chlorambucil and bleomycin
infliximab
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chlorambucil and infliximab
melphalan
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chlorambucil and melphalan
ibritumomab tiuxetan
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chlorambucil and ibritumomab tiuxetan
azathioprine
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chlorambucil and azathioprine
etanercept
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chlorambucil and etanercept
dexamethasone
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chlorambucil and dexamethasone
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web search results for 'chlorambucil'?
Results
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- chlorambucil
MedlinePlus Drug Information: Chlorambucil
Chlorambucil ... Chlorambucil can cause a decrease in the number of blood ... Chlorambucil may interfere with the normal menstrual cycle (period) in women and ...
http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a682899.html
www.nlm.nih.gov
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summary
Chlorambucil - Wikipedia, the free encyclopedia
Chlorambucil (marketed as Leukeran by GlaxoSmithKline) is a ... Nitrogen mustards: (Chlorambucil, Chlormethine, Cyclophosphamide, Ifosfamide, Melphalan) ...
http://en.wikipedia.org/wiki/Chlorambucil
en.wikipedia.org
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summary
Chlorambucil advanced consumer information | Drugs.com
Chlorambucil patient information - advanced edition from the United States Pharmacopoeia. ... Chlorambucil interferes with the growth of cancer cells, which ...
http://www.drugs.com/cons/Chlorambucil.html
www.drugs.com
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CHLORAMBUCIL - ORAL (Leukeran) side effects, medical uses, and drug interactions.
Read more about the prescription drug CHLORAMBUCIL - ORAL. ... WARNING: Chlorambucil can cause cancer or weaken your bone marrow. ...
http://www.medicinenet.com/chlorambucil-oral/article.htm
www.medicinenet.com
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summary
Chlorambucil CAS No. 305-03-3
Chlorambucil is known to be a human carcinogen based on suf?cient ... a few small epidemiological studies in which chlorambucil, either alone or ...
http://ntp.niehs.nih.gov/ntp/roc/eleventh/profiles/s031chlo.pdf
ntp.niehs.nih.gov
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summary
Chlorambucil
... Chlorambucil. ... Chlorambucil is used to treat chronic lymphocytic ... Chlorambucil should be used only under the supervision of a medical oncologist ...
http://www.webmd.com/cancer/chlorambucil
www.webmd.com
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summary
Chlorambucil (Oral Route) - MayoClinic.com
Mayo Clinic offers award-winning medical and health information and tools for healthy living. ... Chlorambucil interferes with the growth of cancer cells, ...
http://www.mayoclinic.com/health/drug-information/DR600335
www.mayoclinic.com
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summary
Chlorambucil - Yahoo! Health
Chlorambucil should only be prescribed by a qualified healthcare provider experienced in the use of cancer chemotherapeutic agents.
http://health.yahoo.com/cancer-medications/chlorambucil/heal...
health.yahoo.com
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summary
Leukeran - Chlorambucil - Dosage - Side Effects - Interactions - Warnings
Leukeran (chlorambucil) drug information, dosage, side effects, drug interactions, and warnings. ... Medications> A - Z: DMARDs> Leukeran (Chlorambucil) ...
http://arthritis.about.com/od/leukeran/Leukeran_Chlorambucil...
arthritis.about.com
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Leukeran (Chlorambucil) drug description - prescription drugs and medications at RxList
Find Leukeran (Chlorambucil) medication description and details on prescription drugs. ... Chlorambucil is probably mutagenic and teratogenic in humans. ...
http://www.rxlist.com/cgi/generic/leukeran.htm
www.rxlist.com
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summary
chlorambucil
Prev Term: chloral hydrate. Next Term: chloramphenicol. chlorambucil. Broader Terms: ... nitrogen mustard alkylating agent used as antineoplastic for ...
http://crisp.cit.nih.gov/Thesaurus/00001589.htm
crisp.cit.nih.gov
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summary
MedDet
Applications submitted to the WHO Secretariat for the 15th WHO ... Lists by country. WHO related links. Other useful sites. Medicine Use(s) : CHLORAMBUCIL ...
http://mednet3.who.int/EMLib/DiseaseTreatments/MedicineDetai...
mednet3.who.int
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summary
Chlorambucil facts and comparsions at Drugs.com
All about Chlorambucil. View complete and up to date Chlorambucil information - part of the Drugs.com trusted medication database.
http://www.drugs.com/cdi/chlorambucil.html
www.drugs.com
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Fludarabine Prolongs Leukemia Remission - National Cancer Institute
... more and longer remissions than chlorambucil, according to the December 14, 2000, ... therapy, producing responses in patients who had not responded to chlorambucil. ...
http://www.nci.nih.gov/clinicaltrials/results/fludarabine-prolongs-remission1200
www.nci.nih.gov
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summary
Chlorambucil - Wikipedia
Chlorambucil wirkt zytostatisch und ist immunsuppressiv. ... Wie andere Zytostatika auch ist Chlorambucil erbgut- und fruchtschädigend. ...
http://de.wikipedia.org/wiki/Chlorambucil
de.wikipedia.org
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Drugs and Treatments - Chlorambucil Oral - Patient Handout from WebMD
Information on Chlorambucil Oral - Patient Handout. Find the answers you need about over the counter and prescription medications, vitamins and supplements, and much ...
http://www.webmd.com/drugs/drug-14006-Chlorambucil+Oral.aspx...
www.webmd.com
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NIOSH/Health Care Workers Guidelines/Chap5a (continued)
... (e.g. cyclophosphamide and chlorambucil) (Sorsa et al 1985) ... indicated that cyclophosphadmide, chlorambucil, 1,4-butanediol dimethylsulfonate, ...
http://www.cdc.gov/niosh/hcwold5a.html
www.cdc.gov
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Chlorambucil - Yahoo! Health
Chlorambucil is available as a pill you can swallow. ... Chlorambucil is used to treat chronic lymphocytic leukemia (CLL) and non ...
http://health.yahoo.com/cancer-medications/chlorambucil/healthwise--tv7485.html
health.yahoo.com
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summary
chlorambucil Side Effects, Interactions and Information - Drugs.com
Learn all about chlorambucil side effects and interactions. ... Chlorambucil can lower the blood cells that help your body fight infections. ...
http://www.drugs.com/MTM/chlorambucil.html
www.drugs.com
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chlorambucil-oral Glossary of Terms with Definitions on MedicineNet.com
chlorambucil-oral glossary includes a list of chlorambucil-oral related medical definitions and related links on MedicineNet.com
http://www.medicinenet.com:9003/chlorambucil-oral/glossary.htm
www.medicinenet.com:9003
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summary
Cancer Medicine
The editors have strived to make every chapter in this book present the ... methotrexate, actinomycin D, and chlorambucil, remained popular throughout the ...
http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=cmed6.section.28610
www.ncbi.nlm.nih.gov
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summary
NTP: ChemIDPlus/HSDB 305-03-3 Toxicity
CHLORAMBUCIL INDUCES ... WHO BECAME PREGNANT WHILE RECEIVING CHLORAMBUCIL TREATMENT (6 MG/DAY) HAD ... DURING AND AFTER TREATMENT WITH CHLORAMBUCIL. ...
http://ntp.niehs.nih.gov/index.cfm?objectid=E87F4ACB-BDB5-82F8-FA8FAF1CD133497A
ntp.niehs.nih.gov
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summary
Drugs and Treatments - Chlorambucil Misc - Patient Handout from WebMD
Information on Chlorambucil Misc - Patient Handout. Find the answers you need about over the counter and prescription medications, vitamins and supplements, and much ...
http://www.webmd.com/drugs/drug-20390-Chlorambucil%20Misc.as...
www.webmd.com
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TA119 Leukaemia (lymphocytic) - fludarabine: Guidance
chlorambucil for a 15-year time horizon was £28,178 per QALY. ... monotherapy compared with chlorambucil, and noted that the ...
http://www.nice.org.uk/nicemedia/pdf/TA119Guidance.pdf
www.nice.org.uk
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Definition of chlorambucil - NCI Dictionary of Cancer Terms
Estimating African American Breast Cancer Risk More Accurately ... chlorambucil. An anticancer drug that belongs to the family of drugs called alkylating agents. ...
http://www.nci.nih.gov/templates/db_alpha.aspx?CdrID=46048
www.nci.nih.gov
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List of chemotherapeutic agents - Wikipedia, the free encyclopedia
This is a list of specific pharmacologic agents that ... Chlorambucil. Cyclophosphamide. Cytarabine. Daunorubicin. Docetaxel. Doxifluridine. Doxorubicin ...
http://en.wikipedia.org/wiki/List_of_chemotherapeutic_agents
en.wikipedia.org
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summary
Chlorambucil Side Effects | Drugs.com
Comprehensive and accurate Chlorambucil side effects information for consumers and healthcare professionals. ... Chlorambucil ...
http://www.drugs.com/sfx/chlorambucil-side-effects.html
www.drugs.com
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summary
Emedicine Search Results for chlorambucil
... in that category. Searched Articles for "chlorambucil" ... Searched Articles for "chlorambucil" Returned 88 Records Next 20. Page 1 2 3 4 5 ...
http://www.emedicine.com/cgi-bin/foxweb.exe/searchengine@/em...
www.emedicine.com
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Drugs and Treatments - Chlorambucil Misc - Side Effects from WebMD
Information on Chlorambucil Misc - Side Effects. Find the answers you need about over the counter and prescription medications, vitamins and supplements, and much more.
http://www.webmd.com/drugs/drug-20390-Chlorambucil+Misc.aspx...
www.webmd.com
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Leukeran (chlorambucil) medical facts from Drugs.com
Physician reviewed Leukeran patient information - includes Leukeran description, dosage and directions. ... Treatment with chlorambucil may increase your risk ...
http://www.drugs.com/mtm/leukeran.html
www.drugs.com
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NIDDK Clearinghouses Publications Catalog
Cyclophosphamide and chlorambucil significantly reduced the relapse risk at 6 to ... conclude that cyclophosphamide, chlorambucil, cyclosporine, and levamisole ...
http://catalog.niddk.nih.gov/resources/results.cfm?searchter...
catalog.niddk.nih.gov
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Chlorambucil-induced mutations in mice recovered in homozygotes.
Chlorambucil induced a number of recessive visible mutations in the mouse. ... as high as 25% after a dose of 10 mg of chlorambucil per kg to early spermatids. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=48762
www.pubmedcentral.nih.gov
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Drugs and Treatments - Chlorambucil Misc - Warnings from WebMD
Information on Chlorambucil Misc - Warnings. Find the answers you need about over the counter and prescription medications, vitamins and supplements, and much more.
http://www.webmd.com/drugs/drug-20390-Chlorambucil+Misc.aspx...
www.webmd.com
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Chronic Lymphocytic Leukemia Treatment - National Cancer Institute
Expert-reviewed information summary about the treatment of ... A randomized clinical trial of chlorambucil versus COP in stage B chronic lymphocytic leukemia. ...
http://www.nci.nih.gov/cancertopics/pdq/treatment/CLL/HealthProfessional/page6
www.nci.nih.gov
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Biological half-life - Wikipedia, the free encyclopedia
The biological half-life of a substance is the time required for ... 1.3.7 Chlorambucil. 1.3.8 Oxaliplatin. 1.4 Metals. 2 Maths. 2.1 Zero-order elimination ...
http://en.wikipedia.org/wiki/Elimination_half_life
en.wikipedia.org
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Leukemia: Medications - Yahoo! Health
Find information on leukemia including lymphocytic leukemia, myeloid leukemia, ... Chlorambucil should only be prescribed by a qualified healthcare provider ...
http://health.yahoo.com/leukemia-medications?ctype=drug
health.yahoo.com
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Drugs and Treatments - Chlorambucil Misc - Precautions from WebMD
Information on Chlorambucil Misc - Precautions. Find the answers you need about over the counter and prescription medications, vitamins and supplements, and much more.
http://www.webmd.com/drugs/drug-20390-Chlorambucil+Misc.aspx...
www.webmd.com
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Leukeran Official FDA information, side effects and uses.
Accurate, FDA approved Leukeran information for healthcare professionals ... Chlorambucil is rapidly and completely absorbed from the gastrointestinal tract. ...
http://www.drugs.com/pro/leukeran.html
www.drugs.com
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Biological half-life - Wikipedia, the free encyclopedia
It has been suggested that Effective half-life be merged into ... 1.3.7 Chlorambucil. 1.3.8 Oxaliplatin. 1.4 Metals. 2 Maths. 2.1 Zero-order elimination ...
http://en.wikipedia.org/wiki/Biological_halflife
en.wikipedia.org
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Diseases and Conditions Encyclopedia : Discovery Health
Chronic lymphocytic leukemia (CLL), is a kind of cancer that occurs in a ... Sometimes CLL can be become very active very quickly. ...
http://health.discovery.com/encyclopedias/illnesses.html?chr...
health.discovery.com
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Leukaemia (lymphocytic) - fludarabine (appraisal consultation document)
... fludarabine monotherapy, fludarabine plus cyclophosphamide and chlorambucil. ... treatment and repeated treatment with chlorambucil may be effective and more ...
http://www.nice.org.uk/page.aspx?o=373472
www.nice.org.uk
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WebMD Health - Drug Search results for Chlorambucil
Bookmark This Page. Site Map. Sign up for WebMD Newsletters ... Your search for Chlorambucil returned 2 results. Exact matches for Chlorambucil. Drug Name ...
http://www.webmd.com/drugs/search.aspx?stype=DRUG&query=Chlorambucil
www.webmd.com
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Definition of chlorambucil - National Cancer Institute Drug Dictionary
chlorambucil. An orally-active antineoplastic aromatic nitrogen mustard. Chlorambucil alkylates and cross-links DNA during all phases of the cell cycle, ...
http://www.nci.nih.gov/Templates/drugdictionary.aspx?CdrID=43113
www.nci.nih.gov
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Leukeran Drug Information, Professional
Leukeran Drug Information from Drugs.com. Includes Leukeran side effects, ... Chlorambucil is cell cycle?phase nonspecific, although it is also cytotoxic to ...
http://www.drugs.com/mmx/leukeran.html
www.drugs.com
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NIDDK : Clinical Research : Focal Segmental Glomerulosclerosis (FSGS) in Children and Young Adults Interventional ...
... immunomodulatory agents, cyclophosphamide and chlorambucil, have been used for ... experience with cyclophosphamide and chlorambucil (Latta et al., Pediatric ...
http://www.niddk.nih.gov/patient/fsgs/fsgs.htm
www.niddk.nih.gov
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Fludarabine - Wikipedia, the free encyclopedia
... Fludarabine compared with chlorambucil as primary therapy for ... Nitrogen mustards: (Chlorambucil, Chlormethine, Cyclophosphamide, Ifosfamide, Melphalan) ...
http://en.wikipedia.org/wiki/Fludarabine
en.wikipedia.org
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Drug points: Fatal erythroderma associated with pentostatin
She was treated with chlorambucil 10mg/day. ... view of her failure to respond, chlorambucil was discontinued and she was given ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=28207
www.pubmedcentral.nih.gov
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Chlorambucil Drug Interactions - Drugs.com
Chlorambucil Drug Interactions. Drug-drug and drug-food interactions for Chlorambucil ... to view Drug-Drug Interactions with chlorambucil. Major Interactions ...
http://www.drugs.com/drug-interactions/chlorambucil_d00188.html
www.drugs.com
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Systemic Lupus Erythematosus (SLE) Causes, Symptoms, Treatment, Signs and Information on MedicineNet.com
Get information on lupus (SLE) disease treatment, signs, diagnosis, types of symptoms (butterfly, discoid rash), causes ... chlorambucil-oral, Leukeran ...
http://www.medicinenet.com/script/main/forum.asp?articlekey=...
www.medicinenet.com
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Drugs and Treatments - Leukeran Oral - Patient Handout from WebMD
Information on Leukeran Oral - Patient Handout. Find the answers you need about over ... Chlorambucil treatment can be associated with serious side effects. ...
http://www.webmd.com/drugs/drug-14011-Leukeran%20Oral.aspx?d...
www.webmd.com
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