Cefepime ( INN ) (pronounced /?s?f?pi?m/, /?k?f?pi?m/ ) is a fourth-generation cephalosporin antibiotic developed in 1994. Cefepime has an extended spectrum of activity against Gram-positive and Gram-negative bacteria , with greater activity against both Gram-negative and Gram-positive organisms than third-generation agents. more

Cefepime ( INN ) (pronounced /?s?f?pi?m/, /?k?f?pi?m/ ) is a fourth-generation cephalosporin antibiotic developed in 1994. Cefepime has an extended spectrum of activity against Gram-positive and Gram-negative bacteria , with greater activity against both Gram-negative and Gram-positive organisms than third-generation agents. Cefepime hydrochloride was first marketed in 1994 and is currently marketed under various trade names including Neopime(neomed) Maxipime, Maxcef, Cepimax, Cepimex, and Axepim. A 2007 meta-analysis suggested that when data of trials were combined, mortality was increased in patients treated with cefepime compared with other antibiotics. [ 1 ] In response, the U.S. Food and Drug Administration issued an early communication about ongoing safety review that would take about four months to conduct. [ 2 ] less