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what is 'topotecan hydrochloride'? Definition for Topotecan hydrochloride Topotecan hydrochloride (trade name Hycamtin ) is a chemotherapy agent that is a topoisomerase 1 inhibitor . It is the first camptothecin . It is used to treat ovarian cancer and lung cancer , as well as other cancer types. more Topotecan hydrochloride (trade name Hycamtin ) is a chemotherapy agent that is a topoisomerase 1 inhibitor . It is the first camptothecin . It is used to treat ovarian cancer and lung cancer , as well as other cancer types. After GlaxoSmithKline received final FDA approval for Hycamtin Capsules on October 15, 2007, Topotecan is the first topoisomerase inhibitor for oral use. 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MEDgle does not recommend any particular type of physician or claim to be complete or accurate in the providers and specialties suggested. web search results for 'topotecan hydrochloride'? Results 1 - 50 - Topotecan Topotecan - Wikipedia, the free encyclopedia Topotecan hydrochloride (Hycamtin) is a chemotherapy agent that ... NCI Drug Dictionary Definition of Topotecan. NCI Drug Information for Patients. v ? d ? e ... http://en.wikipedia.org/wiki/Topotecan   en.wikipedia.org - summary Topotecan Drug details for Topotecan. ... Topotecan is a topoisomerase inhibitor that stops the growth of cancer cells by ... Topotecan should only be administered under ... http://www.webmd.com/cancer/topotecan   www.webmd.com - summary Hycamtin (Topotecan Hydrochloride) drug description - prescription drugs and medications at RxList Find Hycamtin (Topotecan Hydrochloride) medication description and details on prescription drugs. http://www.rxlist.com/cgi/generic2/topotec.htm   www.rxlist.com - summary topotecan-injection Glossary of Terms with Definitions on MedicineNet.com topotecan-injection glossary includes a list of topotecan-injection related medical definitions and related links on MedicineNet.com http://www.medicinenet.com/topotecan-injection/glossary.htm   www.medicinenet.com - summary topotecan medical facts from Drugs.com Physician reviewed topotecan patient information - includes topotecan description, dosage and directions. ... Do not use topotecan without telling your doctor ... http://www.drugs.com/mtm/topotecan.html   www.drugs.com - summary Topotecan - Yahoo! Health Topotecan should only be administered under the supervision of a qualified healthcare provider experienced in the use of cancer chemotherapeutic agents. http://health.yahoo.com/cancer-medications/topotecan/healthwise--d04014a1.html   health.yahoo.com - summary MedlinePlus Drug Information: Topotecan Hydrochloride ... and pharmacist if you are allergic to topotecan or any other drugs. ... you should know that topotecan may interfere with the normal ... Topotecan may ... http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a697006.html   www.nlm.nih.gov - summary Topotecan and Advanced Cervical Cancer - National Cancer Institute ... of cisplatin (Platinol®) and topotecan (Hycamtin®) lived a few months ... by 24 percent for patients receiving the topotecan plus cisplatin combination. ... http://www.nci.nih.gov/clinicaltrials/results/topotecan0805   www.nci.nih.gov - summary Topotecan (Intravenous Route) - MayoClinic.com Mayo Clinic offers award-winning medical and health information and tools for healthy living. ... Topotecan belongs to the group of medicines known as ... http://www.mayoclinic.com/health/drug-information/DR601359   www.mayoclinic.com - summary Full guidance on topotecan for ovarian cancer - text (html) version Drugs other than topotecan used in second-line and subsequent therapy have not ... those of paclitaxel, caelyx and topotecan, but the selection of patients ... http://www.nice.org.uk/article.asp?a=18692   www.nice.org.uk - summary Clinical Study: 05-C-0186, A Pilot Trial of Oral Topotecan for the Treatment of Refractory Advanced Solid Neoplasms ... Clinical Study Summary Sheet ... A Pilot Trial of Oral Topotecan for the Treatment of Refractory ... chronic administration of topotecan inhibits HIF-1alpha ... http://clinicalstudies.info.nih.gov/detail/A_2005-C-0186.html   clinicalstudies.info.nih.gov - summary TOPOTECAN - INJECTION (Hycamtin) side effects, medical uses, and drug interactions. Read more about the prescription drug TOPOTECAN - INJECTION. ... Topotecan should only be used under close medical supervision. ... http://www.medicinenet.com/topotecan-injection/article.htm   www.medicinenet.com - summary Using plasma topotecan pharmacokinetics to estimate topotecan exposure in cerebrospinal fluid of children with ... ... ventricular cerebrospinal fluid (vCSF) topotecan lactone (TPT) exposures in ... Topotecan, a DNA topoisomerase I inhibitor with activity against medulloblastoma, ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1871944   www.pubmedcentral.nih.gov - summary Drugs and Treatments - Topotecan IV - Patient Handout from WebMD Find information about (Topotecan IV) on WebMD including drug user ratings, drug interactions, medication warnings, medical uses, side effects and recommended dosage. http://www.webmd.com/drugs/drug-13492-Topotecan+IV.aspx?drug...   www.webmd.com - summary Topotecan - Wikipedia Topotecan lagert sich dem Komplex aus DNA Topoisomerase I und DNA an und ... in der S-Phase des Zellzyklus sind, werden durch Topotecan nicht geschädigt. ... http://de.wikipedia.org/wiki/Topotecan   de.wikipedia.org - summary Success Story: Topotecan (NSC 609699) ... toxicology studies, production, and phase I clinical trials of topotecan. ... Topotecan is one of four NCDDG-developed agents approved by the FDA since the ... http://dtp.nci.nih.gov/timeline/flash/success_stories/s14_topotecan.htm   dtp.nci.nih.gov - summary Topotecan facts and comparsions at Drugs.com All about Topotecan. View complete and up to date Topotecan information - part of the Drugs.com ... Topotecan may cause severe and sometimes fatal bone ... http://www.drugs.com/cdi/topotecan.html   www.drugs.com - summary Topotecan Hydrochloride - National Cancer Institute ... contains brief information about topotecan hydrochloride and a collection of ... Topotecan hydrochloride is approved by the Food and Drug Administration (FDA) to ... http://www.nci.nih.gov/cancertopics/druginfo/topotecanhydrochloride   www.nci.nih.gov - summary Topotecan (Oral Route) - MayoClinic.com Mayo Clinic offers award-winning medical and health information and tools for healthy living. ... Topotecan interferes with the growth of cancer cells, which ... http://www.mayoclinic.com/health/drug-information/DR602559   www.mayoclinic.com - summary MedlinePlus Medicinas: Clorhidrato de topotecán El topotecán pertenece a una clase de medicamentos ... dígale a su doctor y a su farmacéutico si usted es alérgico al topotecán o a otros medicamentos. ... http://www.nlm.nih.gov/medlineplus/spanish/druginfo/medmaster/a697006-es.html   www.nlm.nih.gov - summary Talk:Topotecan - Wikipedia, the free encyclopedia Topotecan is part of WikiProject Pharmacology, a project to improve all ... Articles, Links The role of topotecan in the treatment of brain metastases. ... http://en.wikipedia.org/wiki/Talk:Topotecan   en.wikipedia.org - summary Topotecan - Yahoo! Health Topotecan is an intravenous (IV) medication usually given in a dose based on body weight. ... Topotecan is a topoisomerase inhibitor that stops the growth of ... http://health.yahoo.com/cancer-medications/topotecan/healthwise--tw10153.html   health.yahoo.com - summary Paclitaxel, pegylated liposomal doxorubicin hydrochloride and topotecan for second-line Topotecan is now only recommended for the treatment of women with platinum ... Topotecan is recommended as an option for second-line (or subsequent) ... http://www.nice.org.uk/page.aspx?o=TA091guidance   www.nice.org.uk - summary Hycamtin (topotecan) medical facts from Drugs.com Physician reviewed Hycamtin patient information - includes Hycamtin description, dosage and directions. ... Do not use topotecan without telling your doctor if ... http://www.drugs.com/mtm/hycamtin.html   www.drugs.com - summary Definition of 11C topotecan - National Cancer Institute Drug Dictionary ... phase of the cell cycle, topotecan inhibits topoisomerase I activity by ... tomography (PET) may help predict responses to topotecan therapy. ... http://cancertrials.nci.nih.gov/Templates/drugdictionary.aspx?CdrID=454314   cancertrials.nci.nih.gov - summary Drugs and Treatments - Topotecan IV - Drug Images from WebMD Find the answers you need about over the counter and prescription medications, vitamins and supplements including images of different dosages and formulations. http://www.webmd.com/drugs/drug-13492-Topotecan+IV.aspx?drug...   www.webmd.com - summary Clinical Study: 07-C-0203, A Phase I Study of ABT-888 in Combination With Topotecan Hydrochloride in Adults With ... Clinical Study Summary ... in Combination With Topotecan Hydrochloride in Adults With ... this reason and because topotecan hydrochloride used in this ... http://clinicalstudies.info.nih.gov/detail/A_2007-C-0203.html   clinicalstudies.info.nih.gov - summary topotecan Prev Term: topoisomerase inhibitor. Next Term: Torental. topotecan. Used for: Hyamptin ... antineoplastic drug which acts as a DNA topoisomerase inhibitor. ... http://crisp.cit.nih.gov/Thesaurus/00008119.htm   crisp.cit.nih.gov - summary 21-day continuous infusion of topotecan in AIDS-associated progressive multifocal leukoencephalopathy (PML). ... day continuous infusion of topotecan in AIDS-associated progressive multifocal ... Background: Topotecan, a DNA topoisomerase I inhibitor, inhibits HIV-1 and JC ... http://gateway.nlm.nih.gov/MeetingAbstracts/102244380.html   gateway.nlm.nih.gov - summary Hycamtin side effects (Topotecan Hydrochloride) and drug interactions - prescription drugs and medications at RxList ... side effects and drug interactions for the drug Hycamtin (Topotecan Hydrochloride) at RxList. ... events in the topotecan/paclitaxel comparator trial in ... http://www.rxlist.com/korean.php?u=http://www.rxlist.com/cgi...   www.rxlist.com - summary Topotecan HCl Topotecan undergoes a reversible, pH-dependent hydrolysis of its lactone moiety. ... Cl, common in the elderly, is an important determinant of topotecan Cl. ... http://www.drugs.com/ppa/topotecan-hcl.html?printable=1   www.drugs.com - summary Appraisal Consultation Document - Topotecan, pegylated liposomal doxorubicin hydrochloride and paclitaxel for second... ... conduct an appraisal of topotecan, pegylated liposomal doxorubicin hydrochloride ... of Product Characteristics states that topotecan is not recommended in people ... http://www.nice.org.uk/page.aspx?o=234447&mode=normal   www.nice.org.uk - summary Definition of topotecan - NCI Dictionary of Cancer Terms Novel Molecular Pattern Linked to Colon ... topotecan (toh-poh-TEE-kan) ... topotecan hydrochloride, toremifene, Torisel, tositumomab, total androgen blockade ... http://www.nci.nih.gov/Templates/db_alpha.aspx?CdrID=45342   www.nci.nih.gov - summary Transcript: Topotecan The net result being that camptothecin was dropped. ... analogs have since actually reached the market in 1996, topotecan and irinotecan. ... http://dtp.nci.nih.gov/timeline/videoclips/transcripts/S14_transcript.htm   dtp.nci.nih.gov - summary Chemotherapy Drugs for Ovarian Cancer Explore what chemotherapy drugs are used to treat ovarian cancer ... Topotecan. Profile for topotecan, or Hycamtin, with side effect information. Vinorelbine ... http://cancer.about.com/od/chemotherapydrug1/index_a.htm   cancer.about.com - summary Complete Topotecan Hydrochloride information from Drugs.com All about Topotecan Hydrochloride. View complete and up to date Topotecan Hydrochloride information - part of the Drugs.com trusted medication database. http://www.drugs.com/ppa/topotecan-hydrochloride.html   www.drugs.com - summary Ovarian cancer - topotecan (replaced by TA91) Full guidance on topotecan for ovarian cancer - text (html) version ... 2001/28 NICE issues Guidance on Topotecan for Ovarian Cancer ... http://www.nice.org.uk/cat.asp?c=18677   www.nice.org.uk - summary Ovarian Epithelial Cancer Recurrent or Persistent Ovarian Epithelial Cancer information ... indicated that the use of topotecan achieved results that were comparable to ... http://www.webmd.com/ovarian-cancer/tc/ncicdr0000062829-recu...   www.webmd.com - summary Definition of topotecan hydrochloride - NCI Dictionary of Cancer Terms topotecan hydrochloride (toh-poh-TEE-kan HY-droh-KLOR-ide) ... topoisomerase II inhibitor RTA 744, topoisomerase inhibitor, topotecan ... http://www.nci.nih.gov/Templates/db_alpha.aspx?CdrID=507692   www.nci.nih.gov - summary topotecan Topoisomerase Drug - Topotecan ... Topotecan is used to treat ovarian cancer, small cell lung cancer, and certain ... Topotecan may also be used for purposes ... http://www.drugs.com/search.php?searchterm=topotecan&is_main_search=1   www.drugs.com - summary Optimal chemotherapy treatment for women with recurrent ovarian cancer In one trial, topotecan was superior to treosulphan in patient progression-free ... then monotherapy with paclitaxel, topotecan, or pegylated liposomal doxorubicin ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2002482   www.pubmedcentral.nih.gov - summary 2001/28 NICE issues Guidance on Topotecan for Ovarian Cancer Topotecan should be considered as one of the treatment options for women with ... Topotecan is not recommended for women who have an ECOG (Eastern Cooperative ... http://www.nice.org.uk/page.aspx?mode=text&o=18695   www.nice.org.uk - summary Treatment Topotecan, a topoisomerase I inhibitor, is one of the most widely used agents in ... is a lot of interest in combining topotecan in some doublet and triplet regimens. ... http://emice.nci.nih.gov/emice/mouse_models/organ_models/ova...   emice.nci.nih.gov - summary Hycamtin Official FDA information, side effects and uses. Accurate, FDA approved Hycamtin information for healthcare professionals and ... Hycamtin (topotecan hydrochloride) for Injection should be administered under ... http://www.drugs.com/pro/hycamtin.html   www.drugs.com - summary Doxil side effects (Doxorubicin Hcl) and drug interactions - prescription drugs and medications at RxList Learn the potential medication side effects and drug interactions for the drug ... adverse reactions from the randomized study of DOXIL compared to topotecan. ... http://www.rxlist.com/korean.php?u=http://www.rxlist.com/cgi...   www.rxlist.com - summary Clinical Trials (PDQ®) - National Cancer Institute Phase I Study of Topotecan Hydrochloride by Convection Enhanced Delivery ... topoisomerase target in the tumor influences response to topotecan hydrochloride. ... http://www.nci.nih.gov/clinical_trials/view_clinicaltrials.a...   www.nci.nih.gov - summary Ovarian cancer (advanced) - paclitaxel, pegylated liposomal doxorubicin hydrochloride and topotecan (review) topotecan as an option for second-line (or subsequent) treatment. ... doxorubicin hydrochloride and topotecan (review): Quick reference guide ... http://www.nice.org.uk/TA091   www.nice.org.uk - summary Nonlinear partial differential equations and applications: The mechanism of topoisomerase I poisoning by a ... ... stranded DNA and bound to the clinically approved anticancer agent Topotecan. Topotecan mimics a DNA base pair and binds at the site of DNA cleavage by ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=137726   www.pubmedcentral.nih.gov - summary Hycamtin Drug Information, Professional Hycamtin Drug Information from Drugs.com. Includes Hycamtin side effects, ... Carcinoma, ovarian (treatment)?Topotecan is indicated for the treatment of ... http://www.drugs.com/mmx/hycamtin.html   www.drugs.com - summary Mayo Clinic medical information and tools for healthy living - MayoClinic.com Mayo Clinic offers award-winning medical and health information and ... Topotecan (Intravenous Route) Topotecan (Oral Route) Toprol XL. Toprol XL. Toprol XL ... http://www.mayoclinic.com/health/drug-information/DrugIndex/range=Tn-Tz   www.mayoclinic.com - summary show more 1  2

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