Tacrolimus (also FK-506 or Fujimycin ) is an immunosuppressive drug whose main use is after allogenic organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection . more

Tacrolimus (also FK-506 or Fujimycin ) is an immunosuppressive drug whose main use is after allogenic organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection . It is also used in a topical preparation in the treatment of severe atopic dermatitis ( eczema ), severe refractory uveitis after bone marrow transplants, and the skin condition vitiligo . It is a 23-membered macrolide lactone discovered in 1984 from the fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis . less