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sunitinib
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what is 'sunitinib'?
Definition for Sunitinib
Sunitinib (marketed as Sutent, and previously known as SU11248) is an oral, small-molecule, multi-targeted receptor tyrosine kinase (RTK) inhibitor that was approved by the FDA for the treatment of renal cell carcinoma (RCC) and imatinib -resistant gastrointestinal stromal tumor (GIST) on January 26, 2006.
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Sunitinib (marketed as Sutent, and previously known as SU11248) is an oral, small-molecule, multi-targeted receptor tyrosine kinase (RTK) inhibitor that was approved by the FDA for the treatment of renal cell carcinoma (RCC) and imatinib -resistant gastrointestinal stromal tumor (GIST) on January 26, 2006. Sunitinib was the first cancer drug simultaneously approved for two different indications. [ 1 ] Sunitinib has become a standard of care for both of these cancers, and is currently being studied for the treatment of many others.
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diagnoses treated with 'sunitinib'
1 - 1 of
1
diagnosis
small intestine carcinoma
small bowel cancer
web search for:
Sunitinib and small intestine carcinoma
related procedures when taking 'sunitinib'
1 - 5 of
25
procedures
Abdominal CAT Scan
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Sunitinib and Abdominal CAT Scan
Biopsy
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Sunitinib and Biopsy
Biopsy small bowel
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Sunitinib and Biopsy small bowel
Blood, Platelet Count
Platelet Count
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Sunitinib and Blood, Platelet Count
Capsule endoscopy
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Sunitinib and Capsule endoscopy
Carcinoembryonic Antigen (CEA)
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Sunitinib and Carcinoembryonic Antigen (CEA)
Colonoscopy
Colonoscopy
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Sunitinib and Colonoscopy
Colonoscopy with retrograde ileoscopy
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Sunitinib and Colonoscopy with retrograde ileoscopy
Complete Blood Count
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Sunitinib and Complete Blood Count
Double-contrast barium enema
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Sunitinib and Double-contrast barium enema
Endoscopic ultrasonography
Endoscopic Ultrasound
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Sunitinib and Endoscopic ultrasonography
Endoscopy
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Sunitinib and Endoscopy
Endoscopy, Upper Gastrointestinal
Endoscopy
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Sunitinib and Endoscopy, Upper Gastrointestinal
Enteroclysis
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Sunitinib and Enteroclysis
KUB
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Sunitinib and KUB
Liver Function Tests
elevated liver enzymes
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Sunitinib and Liver Function Tests
Pancreaticoduodenectomy (Whipple procedure)
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Sunitinib and Pancreaticoduodenectomy (Whipple procedure)
Partial Resection of Intestine with Anastomosis
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Sunitinib and Partial Resection of Intestine with Anastomosis
Pill camera
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Sunitinib and Pill camera
Resection
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Sunitinib and Resection
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related medication for 'sunitinib'
1 - 5 of
5
drugs
fluorouracil
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Sunitinib and fluorouracil
imatinib mesylate
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Sunitinib and imatinib mesylate
irinotecan
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Sunitinib and irinotecan
leucovorin
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Sunitinib and leucovorin
oxaliplatin
web search for:
Sunitinib and oxaliplatin
The following are types of physicians relevant for 'Sunitinib'.
related types of physicians 'family practitioner, gastroenterologist, internist, oncologist'
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web search results for 'sunitinib'?
Results
1 - 50
- Sunitinib
Sunitinib - Wikipedia, the free encyclopedia
Description of targeted therapy drug includes indications for therapy and links. ... Sunitinib inhibits cellular signaling by targeting multiple RTKs. ...
http://en.wikipedia.org/wiki/Sunitinib
en.wikipedia.org
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summary
Sunitinib facts and comparsions at Drugs.com
All about Sunitinib. View complete and up to date Sunitinib information - part of the Drugs.com trusted medication database. ... Sunitinib may cause dizziness. ...
http://www.drugs.com/cdi/sunitinib.html
www.drugs.com
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summary
MedlinePlus Drug Information: Sunitinib
Sunitinib ... Other medications may also interact with sunitinib, so be sure to tell your ... You should not breast-feed while you are taking sunitinib. ...
http://www.nlm.nih.gov/medlineplus/druginfo/meds/a607052.html
www.nlm.nih.gov
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Sutent (Sunitinib Malate) drug description - FDA approved labeling for ...
Find Sutent (Sunitinib Malate) medication description and FDA approved drug information including side effects, interactions and patient labeling.
http://www.rxlist.com/cgi/generic/sutent.htm
www.rxlist.com
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Sunitinib Malate (Oral Route) - MayoClinic.com
Mayo Clinic offers award-winning medical and health information and tools for healthy living. ... Sunitinib malate belongs to the group of medicines known as ...
http://www.mayoclinic.com/health/drug-information/DR602399
www.mayoclinic.com
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Sunitinib and Temsirolimus for Kidney Cancer - National Cancer Institute
In separate clinical trials, two new targeted drugs - sunitinib (Sutent®) and temsirolimus - have shown positive results in patients with advanced kidney cancer, ...
http://www.nci.nih.gov/clinicaltrials/results/sunitinib-and-temsirolimus0606
www.nci.nih.gov
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summary
Definition of sunitinib - NCI Dictionary of Cancer Terms
Sunitinib is also used to treat advanced kidney cancer and is being studied in ... sunitinib malate, sunscreen, superficial, superfractionated radiation therapy, ...
http://cancertrials.nci.nih.gov/Templates/db_alpha.aspx?CdrID=492233
cancertrials.nci.nih.gov
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summary
Efficacy and safety of sunitinib in patients with ...[Lancet. 2006 ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and other life science journals for biomedical ...
http://www.ncbi.nlm.nih.gov/pubmed/17046465
www.ncbi.nlm.nih.gov
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Sunitinib malate - PubChem Public Chemical Database
PubChem Compound Summary ... Sunitinib malate - Substance Summary (SID: 47208059) ... SUTENT, an oral multi-kinase inhibitor, is the malate salt of sunitinib. ...
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=47208059
pubchem.ncbi.nlm.nih.gov
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summary
Circulating protein biomarkers of pharmacodynamic activity of sunitinib ...
Sunitinib has been studied in two, independent, open-label phase II studies of ... Based on these findings, sunitinib received accelerated approval in 2006 from ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1939830
www.pubmedcentral.nih.gov
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summary
Clinical Study: 07-C-0220, A Phase I Study of Sunitinib (SU11248), an ...
Clinical Study Summary ... Sunitinib is approved by the Food and Drug Administration for ... the highest dose of sunitinib that can be safely given ...
http://clinicalstudies.info.nih.gov/cgi/detail.cgi?A_2007-C-0220.html
clinicalstudies.info.nih.gov
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Cancer Drug Tied to Heart Problems - Cancer Information (Cancers ...
Information on many different cancers includes symptoms, cancer detection and ... All patients taking sunitinib, but especially those who have risks for heart ...
http://www.medicinenet.com/script/main/art.asp?articlekey=85835
www.medicinenet.com
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summary
Complete Sunitinib Malate information from Drugs.com
All about Sunitinib Malate. View complete and up to date Sunitinib Malate information - part of the Drugs.com trusted medication database.
http://www.drugs.com/ppa/sunitinib-malate.html
www.drugs.com
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Talk:Sunitinib - Wikipedia, the free encyclopedia
Sunitinib is part of WikiProject Pharmacology, a project to improve all ... Retrieved from "http://en.wikipedia.org/wiki/Talk:Sunitinib" ...
http://en.wikipedia.org/wiki/Talk:Sunitinib
en.wikipedia.org
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Sunitinib Linked to Heart Failure and Hypertension - National Cancer ...
Patients taking sunitinib (Sutent®) should be monitored for cardiovascular side ... Sunitinib is approved to treat advanced renal cell carcinoma and metastatic GIST ...
http://www.nci.nih.gov/cancertopics/treatment/sunitinib-cardiotoxicity0108
www.nci.nih.gov
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summary
Phase II testing of sunitinib: the National Cancer Institute of Canada ...
Sunitinib (SU11248) is an orally bioavailable inhibitor that affects the ... Sunitinib is one such agent. ... i testing of sunitinib has demonstrated single ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1948864
www.pubmedcentral.nih.gov
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summary
Sunitinib - PubChem Public Chemical Database
PubChem Compound Summary ... multi-kinase inhibitor, is the malate salt of sunitinib. Sunitinib malate is described chemically as Butanedioic acid, hydroxy ...
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=5329102
pubchem.ncbi.nlm.nih.gov
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Sutent (sunitinib) medical facts from Drugs.com
Physician reviewed Sutent patient information - includes Sutent description, dosage and directions. ... Do not use sunitinib if you are pregnant. ...
http://www.drugs.com/mtm/sutent.html
www.drugs.com
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summary
Renal cell carcinoma - bevacizumab, sorafenib, sunitinib and ...
Bevacizumab, sorafenib, sunitinib and temsirolimus for the ... Sunitinib is ... The average daily cost of sunitinib is £74.74, with an average 6-week ...
http://www.nice.org.uk/guidance/index.jsp?action=article&o=41473
www.nice.org.uk
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summary
Cardiotoxicity associated with tyrosine kinase inh...[Lancet. 2007 ...
PubMed is a service of the U.S. National Library of Medicine that includes over ... Sunitinib malate for the treatment of metastatic renal cell carcinoma and ...
http://www.ncbi.nlm.nih.gov/pubmed/18083403?ordinalpos=1&ito...
www.ncbi.nlm.nih.gov
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summary
Clinical Study: 08-C-0168, A Phase II Trial of Sunitinib in the ...
Clinical Study Summary Sheet for 08-C-0168 ... Sunitinib blocks certain proteins on the surface of tumor and blood vessel cells ...
http://clinicalstudies.info.nih.gov/cgi/detail.cgi?A_2008-C-0168.html
clinicalstudies.info.nih.gov
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summary
New Cancer Drug Boosts Blood Pressure - Cancer Information (Cancers ...
Information on many different cancers includes symptoms, cancer detection and ... Besides sunitinib, other so-called VEGF inhibitors have been developed, ...
http://www.medicinenet.com/script/main/art.asp?articlekey=86150
www.medicinenet.com
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summary
Renal Cell Cancer
Stage IV renal cell cancer is defined different stage groupings.The prognosis for any treated renal cell cancer ... Sunitinib received accelerated ...
http://www.webmd.com/cancer/tc/ncicdr0000062894-stage-iv-and...
www.webmd.com
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summary
MedlinePlus Medicinas: Sunitinib
Sunitinib ... El sunitinib se usa para tratar los tumores del estroma gastrointestinal (GIST, ... El sunitinib pertenece a una clase de medicamentos llamados ...
http://www.nlm.nih.gov/medlineplus/spanish/druginfo/meds/a607052-es.html
www.nlm.nih.gov
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summary
Sunitinib Side Effects | Drugs.com
Comprehensive and accurate Sunitinib side effects information for consumers and healthcare professionals. ... side effects for Sunitinib may not be reported. ...
http://www.drugs.com/sfx/sunitinib-side-effects.html
www.drugs.com
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summary
Definition of sunitinib malate - National Cancer Institute Drug Dictionary
Sunitinib blocks the tyrosine kinase activities of vascular endothelial growth ... sunitinib. US brand name: Sutent. Code names: SU011248. SU11248. Chemical ...
http://www.nci.nih.gov/Templates/drugdictionary.aspx?CdrID=299061
www.nci.nih.gov
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Targeted therapy for renal cell carcinoma: a new treatment paradigm
Sunitinib malate, sorafenib tosylate, temsirolimus, and bevacizumab have ... Sunitinib was tolerable, and severe toxicities (grade 3?4) seldom occurred. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1906573
www.pubmedcentral.nih.gov
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summary
Salvation by Registration
itors, sunitinib malate and sorafenib, respective- ly. ... Neither sunitinib nor sorafenib had a significant ... renal-cell carcinoma with sunitinib or sorafenib. ...
http://lhncbc.nlm.nih.gov/lhc/docs/published/2007/pub2007001.pdf
lhncbc.nlm.nih.gov
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summary
Home blood-pressure monitoring in patients receivi...[N Engl J Med ...
PubMed is a service of the U.S. National Library of Medicine that includes over ... erythrodysesthesia secondary to sunitinib treatment resulting in necrotic ...
http://www.ncbi.nlm.nih.gov/pubmed/18172185?ordinalpos=1&ito...
www.ncbi.nlm.nih.gov
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summary
provigil and Sunitinib Drug Interactions
provigil and Sunitinib Drug Interactions. Drug-drug and drug-food interactions between provigil and Sunitinib ... dosage increase for sunitinib to a maximum of ...
http://www.drugs.com/drug-interactions/provigil_d04378_sunitinib_d05717.html
www.drugs.com
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summary
Clinical Study: 08-EI-0129, Pilot Study of Sunitinib Malate for ...
Clinical Study Summary Sheet for 08-EI-0129 ... ( Sunitinib malate has the potential for teratogenic or abortifacient effects, and ...
http://clinicalstudies.info.nih.gov/detail/A_2008-EI-0129.html
clinicalstudies.info.nih.gov
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summary
Renal cell carcinoma - Wikipedia, the free encyclopedia
Sunitinib versus interferon alfa in metastatic renal-cell carcinoma" ... Phase 3 Randomized Trial of Sunitinib malate (SU11248) versus Interferon-alfa as ...
http://en.wikipedia.org/wiki/Kidney_cancer
en.wikipedia.org
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summary
Definition of sunitinib malate - NCI Dictionary of Cancer Terms
Sunitinib malate is also used to treat advanced kidney cancer and ... sulfuric acid, sulindac, sun protection factor, Sun's Soup, sunitinib. Next Definitions: ...
http://www.nci.nih.gov/Templates/db_alpha.aspx?CdrID=468779
www.nci.nih.gov
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summary
Brain metastasis in renal cell cancer responding t...[Anticancer Res ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... effects of sunitinib or sorafenib in ...
http://www.ncbi.nlm.nih.gov/pubmed/18214028
www.ncbi.nlm.nih.gov
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summary
New Preliminary Phase II Data Show Anti-Tumor Activity of Single-Agent ...
NEW YORK--(BUSINESS WIRE)--Sep 26, 2007 - Preliminary results from a new Phase II study provide data on the anti-tumor activity and tolerability of sunitinib ma
http://www.drugs.com/clinical_trials/new-preliminary-phase-i...
www.drugs.com
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summary
Renal cell carcinoma - bevacizumab, sorafenib, sunitinib and temsirolimus
... bevacizumab, sorafenib, sunitinib and temsirolimus: Response ... Renal Cell Carcinoma - bevacizumab, sarofenib and sunitinib: Draft Matrix. 14 August 2007 ...
http://www.nice.org.uk/Guidance/TA/Wave14/22
www.nice.org.uk
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summary
Drugs Slow Kidney Cancer - Cancer Information (Cancers, Symptoms ...
Information on many different cancers includes symptoms, cancer detection and ... As a group, the sunitinib patients also reported significantly better overall ...
http://www.medicinenet.com/script/main/art.asp?articlekey=78950
www.medicinenet.com
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summary
Clinical Study: 07-C-0134, A Phase II Study of Combination Oral CC-5013 ...
Clinical Study Summary ... take lenalidomide, sunitinib and cyclophosphamide daily ... Drug: Sunitinib. Drug: Cyclophosphamide. Supporting Site: National ...
http://clinicalstudies.info.nih.gov/cgi/detail.cgi?A_2007-C-0134.html
clinicalstudies.info.nih.gov
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summary
Randomized, double-blind, placebo-controlled phase...[Clin Genitourin ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... trial of sunitinib in previously ...
http://www.ncbi.nlm.nih.gov/pubmed/18272031?ordinalpos=2687&...
www.ncbi.nlm.nih.gov
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Novel therapies in genitourinary cancer: an update
Quality of life was significantly better in the sunitinib group. ... In patients refractory to sunitinib and sorafenib, the ORR was 7% and median PFS ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2527326
www.pubmedcentral.nih.gov
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Sutent Official FDA information, side effects and uses.
Accurate, FDA approved Sutent information for healthcare professionals and ... Concurrent administration of sunitinib malate with the strong CYP3A4 inhibitor, ...
http://www.drugs.com/pro/sutent.html
www.drugs.com
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Adjuvant Therapy for Kidney Cancer - National Cancer Institute
In this trial, patients who have kidney cancer that can be surgically removed and who are at high risk for recurrence will be given sunitinib (Sutent®), sorafenib ...
http://www.nci.nih.gov/clinicaltrials/ft-ECOG-E2805
www.nci.nih.gov
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summary
Advances in the treatment of gastrointestinal stro...[Ann Oncol. 2007 ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... safety of sunitinib in patients ...
http://www.ncbi.nlm.nih.gov/pubmed/17761719?ordinalpos=8&ito...
www.ncbi.nlm.nih.gov
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summary
Gastrointestinal stromal tumours - sunitinib malate
Sunitinib for the treatment of gastrointestinal stromal tumours ... GIST - sunitinib malate: response to consultee and commentator comments on the draft scope ...
http://www.nice.org.uk/Guidance/TA/Wave18/22
www.nice.org.uk
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summary
Sutent
Information for Sutent on Drugs.com. May include images, interactions and related content. ... Sunitinib may also be used for purposes other than...
http://www.drugs.com/search.php?searchterm=Sutent
www.drugs.com
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Clinical Trials (PDQ®) - National Cancer Institute
Phase II Study of Sunitinib Malate in Patients With Recurrent and/or Metastatic ... Patients receive oral sunitinib malate once daily on days 1-28. Courses repeat ...
http://www.nci.nih.gov/clinical_trials/view_clinicaltrials.a...
www.nci.nih.gov
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summary
eMedicine News
eMedicine features up-to-date, searchable, peer-reviewed medical journals, online physician reference textbooks, and a ... Sunitinib malate shows anti-tumour ...
http://www.emedicine.com/cgi-bin/foxweb.exe/newsitem@/em/new...
www.emedicine.com
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summary
Talk:Semaxanib - Wikipedia, the free encyclopedia
This article has been rated as Stub-Class on the quality scale. [edit] Sunitinib ... to add something on the structural similarity between semaxanib and sunitinib. ...
http://en.wikipedia.org/wiki/Talk:Semaxanib
en.wikipedia.org
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summary
Biomarker May Predict Response to Cancer Therapy - Cancer Information ...
Information on many different cancers includes symptoms, cancer detection and ... response of both cell populations during sunitinib or bevacizumab therapy. ...
http://www.medicinenet.com/script/main/art.asp?articlekey=88612
www.medicinenet.com
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summary
Thymic carcinoid responds to neoadjuvant therapy w...[J Thorac Oncol ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from ... therapy with sunitinib and octreotide: a ...
http://www.ncbi.nlm.nih.gov/pubmed/18166847
www.ncbi.nlm.nih.gov
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summary
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