Primidone is an anticonvulsant of the pyrimidinedione [ 4 ] class whose active metabolites , phenobarbital (major) and phenylethylmalonamide (PEMA) (minor), are also anticonvulsants. It is used mainly to treat complex partial , simple partials , generalized tonic-clonic seizures , myoclonic , akinetic seizures and since the 1980s it has been a valuable alternative to propranolol in the treatment of essential tremor . more

Primidone is an anticonvulsant of the pyrimidinedione [ 4 ] class whose active metabolites , phenobarbital (major) and phenylethylmalonamide (PEMA) (minor), are also anticonvulsants. It is used mainly to treat complex partial , simple partials , generalized tonic-clonic seizures , myoclonic , akinetic seizures and since the 1980s it has been a valuable alternative to propranolol in the treatment of essential tremor . Unlike other anticonvulsants such as carbamazepine and valproic acid , primidone is rarely used in the treatment of bipolar disorder or any other psychiatric problem. It is also not widely used in treatment of neuropathic pain , trigeminal neuralgia , or migraine . Primidone has been occasionally used to treat long QT syndrome , cerebral palsy , and athetosis . less