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mechlorethamine
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what is 'mechlorethamine'?
Definition for mechlorethamine
Mechlorethamine also known as chlormethine , mustine , nitrogen mustard and HN2 and sold under the brand name Mustargen , is the prototype anticancer chemotherapeutic drug.
It belongs to the group of nitrogen mustard alkylating agents .
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Mechlorethamine also known as chlormethine , mustine , nitrogen mustard and HN2 and sold under the brand name Mustargen , is the prototype anticancer chemotherapeutic drug.
It belongs to the group of nitrogen mustard alkylating agents . [ 1 ]
Successful clinical use of mechlorethamine gave birth to the field of anticancer chemotherapy. The drug is an analogue of mustard gas and was derived from chemical warfare research, in particular a 1943 accident in Bari , Italy which exposed civilians and soldiers-- it was noted that white cell counts of exposed patients decreased, suggesting a possible therapy for the cancer Hodgkin's lymphoma .
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diagnoses treated with 'mechlorethamine'
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metastases
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Letterer-Siwe disease
disease resulting from increased histiocytes in body
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multifocal Langerhans cell granulomatosis
multisystem disease caused by increased number of Langerhans cells
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related procedures when taking 'mechlorethamine'
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Radiation Therapy
Use of ionizing radiation or xrays for medical imaging or to treat cancer
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serum immunoglobulins
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Array genomic hybridization
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related medication for 'mechlorethamine'
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drugs
methotrexate
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vinblastine
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mechlorethamine and vinblastine
cyclophosphamide
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5-fluorouracil (5-fu)
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6-mercaptopurine (6-mp)
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actinomycin-d
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alemtuzumab
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mechlorethamine and alemtuzumab
alkylating agents
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mechlorethamine and alkylating agents
altretamine
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anastrozole
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anti tumor antibiotics
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antimetabolites
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arsenic trioxide
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bevacizumab
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bexarotene
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bicalutamide
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bleomycin
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bortezomib
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busulfan
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web search results for 'mechlorethamine'?
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- Mechlorethamine
MedlinePlus Drug Information: Mechlorethamine
Mechlorethamine ... you should know that mechlorethamine may interfere with the normal menstrual ... Mechlorethamine may harm the fetus. ...
http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a682223.html
www.nlm.nih.gov
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Mechlorethamine - Wikipedia, the free encyclopedia
Mechlorethamine also known as chlormethine, mustine, nitrogen mustard and HN2 ... Successful clinical use of mechlorethamine gave birth to the field of anticancer ...
http://en.wikipedia.org/wiki/Mechlorethamine
en.wikipedia.org
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Definition of mechlorethamine - NCI Dictionary of Cancer Terms
Mechlorethamine is a type of alkylating agent. ... mechlorethamine hydrochloride, MEDI-507, medial supraclavicular lymph node, ...
http://www.nci.nih.gov/Templates/db_alpha.aspx?CdrID=46603
www.nci.nih.gov
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Mechlorethamine advanced consumer information | Drugs.com
Mechlorethamine patient information - advanced edition from the United States Pharmacopoeia. ... Mechlorethamine interferes with the growth of problem cells, ...
http://www.drugs.com/cons/mechlorethamine.html
www.drugs.com
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Mechlorethamine - Yahoo! Health
Mechlorethamine should only be administered under the supervision of a qualified healthcare provider experienced in the use of cancer chemotherapeutic agents.
http://health.yahoo.com/cancer-medications/mechlorethamine/h...
health.yahoo.com
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mechlorethamine-injection Glossary of Terms with Definitions on MedicineNet.com
mechlorethamine-injection glossary includes a list of mechlorethamine-injection related medical definitions and related links on MedicineNet.com
http://www.medicinenet.com/mechlorethamine-injection/glossary.htm
www.medicinenet.com
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Mechlorethamine (Topical Route) - MayoClinic.com
Mayo Clinic offers award-winning medical and health information and tools for healthy living. ... Mechlorethamine interferes with the growth of problem cells, ...
http://www.mayoclinic.com/health/drug-information/DR600883
www.mayoclinic.com
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Drugs and Treatments - Mechlorethamine Inj - Patient Handout from WebMD
Find information about (Mechlorethamine Inj) on WebMD including drug user ratings, drug interactions, medication warnings, medical uses, side effects and recommended ...
http://www.webmd.com/drugs/drug-8870-Mechlorethamine+HCl+Inj...
www.webmd.com
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Mustargen (Mechlorethamine HCl) drug description - prescription drugs and medications at RxList
Find Mustargen (Mechlorethamine HCl) medication description and details on prescription drugs.
http://www.rxlist.com/cgi/generic3/mustargen.htm
www.rxlist.com
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Extrahelical cytosine bases in DNA duplexes containing d[GCC]n·d[GCC]n repeats: detection by a mechlorethamine ...
... bases of different formal mismatch pairs can be crosslinked by mechlorethamine. ... C13?C26, we show that two mechlorethamine crosslinks form between C13 and C29 ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=92524
www.pubmedcentral.nih.gov
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Milestone: Early 1950s cancer drugs
... the treatment of cancer were mechlorethamine (NSC 762), ethinyl estradiol (NSC ... Mechlorethamine is used mainly to treat Hodgkin disease and other ...
http://dtp.nci.nih.gov/timeline/noflash/milestones/M2_1949.htm
dtp.nci.nih.gov
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Mechlorethamine facts and comparsions at Drugs.com
All about Mechlorethamine. View complete and up to date Mechlorethamine information - part of the Drugs.com trusted medication database.
http://www.drugs.com/cdi/mechlorethamine.html
www.drugs.com
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NTP: ChemIDPlus/HSDB 55-86-7 Toxicity
... DC potential decreased rapidly after injection of mechlorethamine hydrochloride. ... drugs melphalan, chlorambucil, and mechlorethamine in a rat mammary carcinoma ...
http://ntp.niehs.nih.gov/index.cfm?objectid=E880BAC1-BDB5-82F8-FDF2A8A6CF4F478D
ntp.niehs.nih.gov
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Mecloretamina (Mechlorethamine, Mostaza Nitrogenada, Mustargen
Mecloretamina (Mechlorethamine, Mostaza Nitrogenada, Mustargen. En el Centro ... cáncer mediante el enlazamiento de los bloques edificadores ...
http://www.cc.nih.gov/ccc/patient_education/CaTxsp/meclors.pdf
www.cc.nih.gov
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summary
MECHLORETHAMINE - INJECTION (Mustargen) side effects, medical uses, and drug interactions.
Read more about the prescription drug MECHLORETHAMINE - INJECTION. ... mechlorethamine-injection Index. Glossary ... 11 more mechlorethamine-injection related ...
http://www.medicinenet.com/mechlorethamine-injection/article.htm
www.medicinenet.com
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Drugs and Treatments - Mechlorethamine Inj - Conditions from WebMD
Find information about (Mechlorethamine Inj) on WebMD including drug user ... conditions does this medication treat? Mechlorethamine Inj is used to treat the ...
http://www.webmd.com/drugs/drug-8870-Mechlorethamine%20Inj.a...
www.webmd.com
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What is cyclophosphamide(CTX)? Find the definition for cyclophosphamide(CTX) at WebMD
... compound, nitrogen mustard (mechlorethamine hydrochloride); also a suppressor ... Bookmark This Page. Site Map. Sign up for WebMD Newsletters. WebMD Home ...
http://dictionary.webmd.com/terms/cyclophosphamide.xml
dictionary.webmd.com
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Mechlorethamine (Intravenous Route) - MayoClinic.com
Mayo Clinic offers award-winning medical and health information and tools for healthy living. ... Mechlorethamine interferes with the growth of cancer cells, ...
http://www.mayoclinic.com/health/drug-information/DR600881
www.mayoclinic.com
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Talk:Mechlorethamine - Wikipedia, the free encyclopedia
Mechlorethamine is part of WikiProject Pharmacology, a project to improve all ... Mechlorethamine is within the scope of WikiProject Chemicals, a daughter project ...
http://en.wikipedia.org/wiki/Talk:Mechlorethamine
en.wikipedia.org
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The initial clinical trial of nitrogen mustard.
Am J Surg. 1963 May;105:574-8. The initial clinical trial of ... Mechlorethamine* Substances: Mechlorethamine. PMID: 13947966 [PubMed - indexed for MEDLINE] ...
http://www.ncbi.nlm.nih.gov/pubmed/13947966
www.ncbi.nlm.nih.gov
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Definition of mechlorethamine hydrochloride - NCI Dictionary of Cancer Terms
Mechlorethamine hydrochloride is a type of alkylating agent. ... mean, mean survival time, measles virus, measurable disease, mechlorethamine. Next Definitions: ...
http://www.nci.nih.gov/Templates/db_alpha.aspx?CdrID=559088
www.nci.nih.gov
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Drugs and Treatments - Mechlorethamine Inj - Side Effects from WebMD
Find information about (Mechlorethamine Inj) on WebMD including drug user ... The following side effects are associated with Mechlorethamine Inj: Common side effects: ...
http://www.webmd.com/drugs/drug-8870-Mechlorethamine+Injecti...
www.webmd.com
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Mechlorethamine Side Effects | Drugs.com
Comprehensive and accurate Mechlorethamine side effects information for consumers and healthcare professionals. ... side effects for Mechlorethamine may not be ...
http://www.drugs.com/sfx/mechlorethamine-side-effects.html
www.drugs.com
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Genome-Wide Requirements for Resistance to Functionally Distinct DNA-Damaging Agents
... (cisplatin, oxaliplatin, carboplatin, mechlorethamine, mitomycin C, and psoralen) ... 206 exhibited significant mechlorethamine-dependent fitness defects compared ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pub...
www.pubmedcentral.nih.gov
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chem.sis.nlm.nih.gov
/chemidplus/direct.jsp?name=
Mechlorethamine
http://chem.sis.nlm.nih.gov/chemidplus/direct.jsp?name=Mechlorethamine
chem.sis.nlm.nih.gov
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Living with Cancer Chemotherapy
Mechlorethamine (Nitrogen Mustard, Mustargen. At the Clinical Center referred to ... Mechlorethamine (Nitrogen Mustard, Mustargen. Living with Cancer ...
http://www.cc.nih.gov/ccc/patient_education/CaTxeng/mechlo.pdf
www.cc.nih.gov
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ABVD versus modified stanford V versus MOPPEBVCAD with optional and limited radiotherapy in intermediate- and ...
... vinblastine, mechlorethamine, vincristine, bleomycin, ... Mechlorethamine/administration & dosage. Melphalan/administration & dosage. Middle Aged ...
http://www.ncbi.nlm.nih.gov/pubmed/16172458
www.ncbi.nlm.nih.gov
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Drugs and Treatments - Mechlorethamine Inj - Food Interactions from WebMD
Find information about (Mechlorethamine Inj) on WebMD including drug user ... Mechlorethamine Inj may interact with the following foods: Important: ...
http://www.webmd.com/drugs/drug-8870-Mechlorethamine+HCl+Inj...
www.webmd.com
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Complete Mechlorethamine Hydrochloride information from Drugs.com
All about Mechlorethamine Hydrochloride. View complete and up to date Mechlorethamine Hydrochloride information - part of the Drugs.com trusted medication database.
http://www.drugs.com/ppa/mechlorethamine-hydrochloride.html
www.drugs.com
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Estramustine - Wikipedia, the free encyclopedia
Estramustine (Emcyt®) is a chemotherapy agent used to treat prostate cancer. ... agent similar to mechlorethamine, with estrogen-induced specificity. ...
http://en.wikipedia.org/wiki/Estramustine
en.wikipedia.org
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Cancer & Chemotherapy: Medications - Yahoo! Health
Find information on cancer--basic facts, prevention, symptoms, signs, tests, ... Mechlorethamine should only be administered under the supervision of a qualified ...
http://health.yahoo.com/cancer-medications?pd=healthwise&o=10
health.yahoo.com
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Definition of median - NCI Dictionary of Cancer Terms
Novel Molecular Pattern Linked to Colon Cancer Prognosis ... measurable disease, mechlorethamine, mechlorethamine hydrochloride, MEDI-507, ...
http://www.nci.nih.gov/Templates/db_alpha.aspx?CdrID=44941
www.nci.nih.gov
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Email Article
... form to send a copy of the article below to yourself or a friend. ARTICLE SUMMARY. Mechlorethamine (Intravenous Route) *Send to this e-mail address *Your name ...
http://www.mayoclinic.com/popupnowrap.cfm?objectID=24469AE3-...
www.mayoclinic.com
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Drugs and Treatments - Mechlorethamine Inj - Drug Interactions from WebMD
Find information about (Mechlorethamine Inj) on WebMD including drug user ... Mechlorethamine Inj may interact with the following medications. Severe Interactions: ...
http://www.webmd.com/drugs/drug-8870-Mechlorethamine+Injecti...
www.webmd.com
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Mustargen
Mechlorethamine interferes with the growth of cancer cells and slows their ... Mechlorethamine is used to treat several types of cancer, such as Hodgkin's ...
http://www.drugs.com/mtm/mustargen.html?printable=1
www.drugs.com
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Drugs and Treatments - Mechlorethamine (Bulk) Misc - Warnings from WebMD
Find information about (Mechlorethamine (Bulk) Misc) on WebMD including drug user ratings, drug interactions, medication warnings, medical uses, side effects and ...
http://www.webmd.com/drugs/drug-144940-Mechlorethamine%20(Bu...
www.webmd.com
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Mustargen Official FDA information, side effects and uses.
Accurate, FDA approved Mustargen information for healthcare professionals and ... Mustargen1 (Mechlorethamine HCl) should be administered only under the ...
http://www.drugs.com/pro/mustargen.html
www.drugs.com
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Email Article
Use this form to send a copy of the article below to yourself ... Mechlorethamine (Topical Route) *Send to this e-mail address *Your name *Your e-mail address ...
http://www.mayoclinic.com/popupnowrap.cfm?objectID=2446A0DF-...
www.mayoclinic.com
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List of chemotherapeutic agents - Wikipedia, the free encyclopedia
This is a list of specific pharmacologic agents that are ... Mechlorethamine. Mercaptopurine. Methotrexate. Mitoxantrone. Oxaliplatin. Paclitaxel. Pemetrexed ...
http://en.wikipedia.org/wiki/List_of_chemotherapeutic_agents
en.wikipedia.org
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Definition of medial supraclavicular lymph node - NCI Dictionary of Cancer Terms
Novel Molecular Pattern Linked to Colon Cancer Prognosis ... measles virus, measurable disease, mechlorethamine, mechlorethamine hydrochloride, MEDI-507 ...
http://www.nci.nih.gov/Templates/db_alpha.aspx?CdrID=45779
www.nci.nih.gov
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Mechlorethamine Drug Interactions - Drugs.com
Mechlorethamine Drug Interactions. Drug-drug and drug-food interactions for Mechlorethamine ... mechlorethamine is known to interact with the following drugs: ...
http://www.drugs.com/drug-interactions/mechlorethamine_d01339.html
www.drugs.com
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Mycosis Fungoides and the Sézary Syndrome
... alkylating agents (e.g.,mechlorethamine,cyclophosphamide,or chlorambucil),or the ... Topical mechlorethamine (nitrogen mustard) ...
http://www.webmd.com/cancer/tc/mycosis-fungoides-and-the-sez...
www.webmd.com
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summary
NTP: ChemIDPlus/HSDB 55-86-7 Chemical
Solutions of mechlorethamine hydrochloride decompose on standing; ... . Back to Top ... Mechlorethamine hydrochloride. N-Methyl-bis-beta-chlorethylamine hydrochloride ...
http://ntp.niehs.nih.gov/index.cfm?objectid=E880BAB1-BDB5-82F8-F8130BCAE290928D
ntp.niehs.nih.gov
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ABVD - Wikipedia, the free encyclopedia
This combination of mechlorethamine, vincristine (Oncovin), procarbazine, and ... avoid alkylating agents (such as mechlorethamine), which were thought to be ...
http://en.wikipedia.org/wiki/ABVD
en.wikipedia.org
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Definition of median survival time - NCI Dictionary of Cancer Terms
Novel Molecular Pattern Linked to Colon Cancer Prognosis ... mechlorethamine, mechlorethamine hydrochloride, MEDI-507, medial supraclavicular ...
http://www.nci.nih.gov/Templates/db_alpha.aspx?CdrID=44158
www.nci.nih.gov
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Managing Hazardous Materials Incidents
C People whose skin or clothing is contaminated with nitrogen mustard can ... HN-2: MBA; mechlorethamine; mustine; 2,2'-dichloro-N-methyldiethylamine; dichloren; ...
http://www.atsdr.cdc.gov/MHMI/mmg164.pdf
www.atsdr.cdc.gov
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summary
Mycosis Fungoides and the Sézary Syndrome
... [ 1 ] Topical chemotherapy with mechlorethamine (nitrogen mustard) or carmustine (BCNU) ... with chemotherapy, topical mechlorethamine or PUVA combined ...
http://www.webmd.com/cancer/tc/mycosis-fungoides-and-the-sez...
www.webmd.com
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Ma - Me index - Drugs.com
Mechlorethamine. Mechlorethamine. Mechlorethamine Systemic. mechlorethamine. Mechlorethamine Hydrochloride. Meclan Topical. Meclan. Meclicot. Meclizine ...
http://www.drugs.com/alpha/m4.html
www.drugs.com
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Definition of MEDI-507 - NCI Dictionary of Cancer Terms
Novel Molecular Pattern Linked to Colon Cancer Prognosis ... virus, measurable disease, mechlorethamine, mechlorethamine hydrochloride ...
http://www.nci.nih.gov/Templates/db_alpha.aspx?CdrID=367413
www.nci.nih.gov
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Defects in interstrand cross-link uncoupling do not account for the extreme sensitivity of ERCC1 and XPF cells to ...
... formed by the nitrogen mustard mechlorethamine (9) and those induced following ... For agents such as mechlorethamine and psoralen plus UVA this seems likely to ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=137407
www.pubmedcentral.nih.gov
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