Mazindol is a central nervous system stimulant . It is a tricyclic compound (not to be confused with tricyclic antidepressants ). It is marketed under the brand names Mazanor and Sanorex.

Mazindol is used in short-term (i.e., a few weeks) treatment of exogenous obesity , in combination with a regimen of weight reduction based on caloric restriction , exercise , and behavior modification in patients with a body mass index of 30 kg of body weight per height in meters squared (kg/m2), or in patients with a body mass index of 27 kg/m2 in the presence of risk factors such as hypertension , diabetes , or hyperlipidemia .