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irinotecan hydrochloride
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what is 'irinotecan hydrochloride'?
Definition for Irinotecan hydrochloride - Irinotecan hydrochloride
Irinotecan is a chemotherapy agent that is a topoisomerase 1 inhibitor . Chemically, it is a semisynthetic analogue of the natural alkaloid camptothecin .
Its main use is in colon cancer , particularly in combination with other chemotherapy agents.
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Irinotecan is a chemotherapy agent that is a topoisomerase 1 inhibitor . Chemically, it is a semisynthetic analogue of the natural alkaloid camptothecin .
Its main use is in colon cancer , particularly in combination with other chemotherapy agents. This includes the regimen FOLFIRI which consists of infusional 5-fluorouracil , leucovorin , and irinotecan.
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diagnoses treated with 'irinotecan hydrochloride'
1 - 2 of
2
diagnosis
dehydration
insufficient body water
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Irinotecan hydrochloride and dehydration
malignancy
cancer
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Irinotecan hydrochloride and malignancy
related procedures when taking 'irinotecan hydrochloride'
1 - 5 of
24
procedures
Intravenous (IV) lactated Ringer (LR) solution
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Irinotecan hydrochloride and Intravenous (IV) lactated Ringer (LR) solution
BUN
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Irinotecan hydrochloride and BUN
Complete Blood Count
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Irinotecan hydrochloride and Complete Blood Count
Complete metabolic panel
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Irinotecan hydrochloride and Complete metabolic panel
Serum Creatinine
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Irinotecan hydrochloride and Serum Creatinine
Urinalysis
Examination of urine to detect disease
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Irinotecan hydrochloride and Urinalysis
serum electrolytes
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Irinotecan hydrochloride and serum electrolytes
24-hour urinary sodium
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Irinotecan hydrochloride and 24-hour urinary sodium
Blood, Platelet Count
Platelet Count
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Irinotecan hydrochloride and Blood, Platelet Count
Creatinine clearance
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Irinotecan hydrochloride and Creatinine clearance
Electrolyte Administration
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Irinotecan hydrochloride and Electrolyte Administration
Foley catheter
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Irinotecan hydrochloride and Foley catheter
Intraosseous line
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Irinotecan hydrochloride and Intraosseous line
Intravenous (IV) fluids
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Irinotecan hydrochloride and Intravenous (IV) fluids
Intravenous (IV) normal saline (NS)
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Irinotecan hydrochloride and Intravenous (IV) normal saline (NS)
Oral rehydration therapy
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Irinotecan hydrochloride and Oral rehydration therapy
Urethral catheter
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Irinotecan hydrochloride and Urethral catheter
Urinary electrolytes
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Irinotecan hydrochloride and Urinary electrolytes
Urine osmolality
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Irinotecan hydrochloride and Urine osmolality
serum osmolality
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Irinotecan hydrochloride and serum osmolality
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related medication for 'irinotecan hydrochloride'
1 - 5 of
12
drugs
dextrose 10% and 0.2% sodium chloride
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Irinotecan hydrochloride and dextrose 10% and 0.2% sodium chloride
dextrose 10% and 0.45% sodium chloride
web search for:
Irinotecan hydrochloride and dextrose 10% and 0.45% sodium chloride
dextrose 10% and 0.9% sodium chloride
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Irinotecan hydrochloride and dextrose 10% and 0.9% sodium chloride
dextrose 5% and 0.2% sodium chloride
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Irinotecan hydrochloride and dextrose 5% and 0.2% sodium chloride
dextrose 5% and 0.33% sodium chloride
web search for:
Irinotecan hydrochloride and dextrose 5% and 0.33% sodium chloride
dextrose 5% and 0.45% sodium chloride
web search for:
Irinotecan hydrochloride and dextrose 5% and 0.45% sodium chloride
dextrose 5% and 0.9% sodium chloride
web search for:
Irinotecan hydrochloride and dextrose 5% and 0.9% sodium chloride
lactated ringers, intravenous
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Irinotecan hydrochloride and lactated ringers, intravenous
sodium chloride 0.45%, intravenous
web search for:
Irinotecan hydrochloride and sodium chloride 0.45%, intravenous
dextrose 5% and 0.3% sodium chloride
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Irinotecan hydrochloride and dextrose 5% and 0.3% sodium chloride
dextrose 5% and ringers
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Irinotecan hydrochloride and dextrose 5% and ringers
sodium chloride 0.9%, intravenous
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Irinotecan hydrochloride and sodium chloride 0.9%, intravenous
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The following are types of physicians relevant for 'Irinotecan hydrochloride'.
related types of physicians 'cardiologist, dermatologist, family practitioner, gastroenterologist, hematologist, internist, nephrologist, vascular surgeon'
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web search results for 'irinotecan hydrochloride'?
Results
1 - 50
- Irinotecan
Irinotecan - Wikipedia, the free encyclopedia
Irinotecan is a chemotherapy agent that is a topoisomerase ... Irinotecan Pathway on ... (Camptothecin, Topotecan, Irinotecan, Rubitecan, Belotecan) II ...
http://en.wikipedia.org/wiki/Irinotecan
en.wikipedia.org
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summary
irinotecan medical facts from Drugs.com
... reviewed irinotecan patient information - includes irinotecan description, dosage ... Irinotecan can cause severe diarrhea, which can be life-threatening if ...
http://www.drugs.com/mtm/irinotecan.html
www.drugs.com
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Irinotecan
... for Irinotecan. ... Irinotecan is an antitumor drug that interferes with how cancer ... Irinotecan should be administered only under the supervision of a ...
http://www.webmd.com/cancer/irinotecan
www.webmd.com
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summary
Irinotecan - Yahoo! Health
Your doctor may recommend you have an anti-diarrhea medicine such as loperamide (Imodium) available at all times while you are receiving irinotecan. The anti ...
http://health.yahoo.com/coloncancer-medications/irinotecan/h...
health.yahoo.com
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summary
Camptosar Injection (Irinotecan Hydrochloride) Drug Information: Uses ...
Learn about the prescription medication Camptosar Injection (Irinotecan Hydrochloride), drug uses, dosage, side effects, drug interactions, warnings, and patient ...
http://www.rxlist.com/camptosar-inj-drug.htm
www.rxlist.com
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Irinotecan: Drug Information Provided by Lexi-Comp: Merck Manual ...
The dose of irinotecan should be reduced if there is a clinically significant ... Irinotecan and its active metabolite (SN-38) bind reversibly to topoisomerase ...
http://www.merck.com/mmpe/lexicomp/irinotecan.html
www.merck.com
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IRINOTECAN - INJECTION (Camptosar) side effects, medical uses, and drug ...
Read more about the prescription drug IRINOTECAN - INJECTION. ... Your doctor may temporarily stop irinotecan if severe diarrhea continues. ...
http://www.medicinenet.com/irinotecan-injection/article.htm
www.medicinenet.com
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summary
Irinotecan (Intravenous Route) - MayoClinic.com
Mayo Clinic offers award-winning medical and health information and tools for healthy living. ... Irinotecan interferes with the growth of cancer cells, which ...
http://www.mayoclinic.com/health/drug-information/DR600805/M...
www.mayoclinic.com
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summary
MedlinePlus Drug Information: Irinotecan Injection
Before you begin your treatment with irinotecan, talk to your doctor about what ... You should not become pregnant while you are receiving irinotecan. ...
http://www.nlm.nih.gov/medlineplus/druginfo/meds/a608043.html
www.nlm.nih.gov
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summary
Phase 1 trial of irinotecan plus BCNU in patients with progressive or ...
Irinotecan is a topoisomerase I inhibitor previously shown to be active in the ... Irinotecan dose escalation occurred independently within 2 strata: patients ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1871988
www.pubmedcentral.nih.gov
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Irinotecan toxicity.
Irinotecan toxicity. Anthony L. ... Adjusting irinotecan's dose to the degree of hepatic insufficiency is now established. ... irinotecan. Camptothecin ...
http://www.ncbi.nlm.nih.gov/pubmed/18660722
www.ncbi.nlm.nih.gov
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Irinotecan Not Superior in SCLC - National Cancer Institute
In contrast to earlier findings, irinotecan and cisplatin were no better than ... Small cell lung cancer, irinotecan, etoposide, cisplatin. ...
http://cme.nci.nih.gov/clinicaltrials/results/irinotecan-and-SCLC0505
cme.nci.nih.gov
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summary
irinotecan - PubChem Public Chemical Database
PubChem Compound Summary ... CAMPTOSAR Injection (irinotecan hydrochloride injection) is an antineoplastic ... Irinotecan hydrochloride was clinically ...
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=3750
pubchem.ncbi.nlm.nih.gov
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Irinotecan - Definition of Irinotecan
Irinotecan is a chemotherapy drug used in the treatment of several types of cancers, including ovarian, lung, and colorectal cancer.
http://coloncancer.about.com/od/glossaries/g/Irinotecan.htm
coloncancer.about.com
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summary
Irinotecan ((+)-Irinotecan) - NextBio
Irinotecan is a derivative of camptothecin. ... Objective response of multiply recurrent low-grade gliomas to bevacizumab and irinotecan. ...
http://www.nextbio.com/b/search/ov.nb?q=(%2B)-Irinotecan&type=COMPOUND
www.nextbio.com
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summary
Irinotecan Ineffective After Colon Cancer Surgery - National Cancer ...
Irinotecan should not be added to 5-fluorouracil (5-FU) and leucovorin in the ... Irinotecan Not Effective in Adjuvant Therapy for Colon Cancer ...
http://www.nci.nih.gov/clinicaltrials/results/irinotecan0807
www.nci.nih.gov
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Irinotecan consumer information from Drugs.com
Irinotecan patient ... Irinotecan interferes with the growth of cancer cells, which are ... may occur after treatment with irinotecan has been stopped. ...
http://www.drugs.com/cons/Irinotecan.html
www.drugs.com
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summary
irinotecan-injection Glossary of Terms with Definitions on MedicineNet.com
irinotecan-injection glossary includes a list of irinotecan-injection related medical definitions and related links on MedicineNet.com
http://www.medicinenet.com/irinotecan-injection/glossary.htm
www.medicinenet.com
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summary
Irinotecan - Yahoo! Health
Irinotecan is an ... Irinotecan should be administered only under the supervision of a medical oncologist. ... Irinotecan can cause birth defects. ...
http://health.yahoo.com/cancer-medications/irinotecan/healthwise--tw9452.html
health.yahoo.com
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summary
Drug Information for Irinotecan IV - WebMD
Find medical information for Irinotecan IV including side effects, drug interactions, images and pictures, medication uses, warnings, user ratings and reviews.
http://www.webmd.com/drugs/drug-13700-Irinotecan%20IV.aspx?d...
www.webmd.com
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summary
Erbitux (Cetuximab) Drug Information: Uses, Side Effects, Drug ...
Learn about the prescription medication Erbitux (Cetuximab), drug uses, ... Erbitux®, in combination with irinotecan, is indicated for the treatment of EGFR ...
http://www.rxlist.com/erbitux-drug.htm
www.rxlist.com
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summary
Irinotecan plus folinic acid/continuous 5-fluorouracil as simplified ...
Furthermore, irinotecan schedules of weekly and of once every two or three weeks ... In contrast to the irinotecan and bolus FA/5-FU regimen, which has attracted ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=497044
www.pubmedcentral.nih.gov
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summary
Irinotecan in esophageal cancer.
Irinotecan (CPT-11, Camptosar) has shown promising activity in a number of ... Full doses of weekly irinotecan (65 mg/m2) and cisplatin (30 mg/m2) could be ...
http://www.ncbi.nlm.nih.gov/pubmed/14569846
www.ncbi.nlm.nih.gov
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Cetuximab Combo Confirmed Effective - National Cancer Institute
... cancer and that the cetuximab/irinotecan combination is more effective than cetuximab alone. ... cetuximab (Erbitux®) and irinotecan (CPT-11) shrank tumors ...
http://www.nci.nih.gov/clinicaltrials/results/cetuximab-combo-effective0603
www.nci.nih.gov
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summary
Loperamide: Drug Information Provided by Lexi-Comp: Merck Manual ...
Irinotecan-induced diarrhea (unlabeled use): 4 mg after first loose or frequent ... ML, Eckardt JR, Kuhn JG, et al, "Phase II Trial of Irinotecan in Patients With ...
http://www.merck.com/mmpe/lexicomp/loperamide.html
www.merck.com
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summary
bexarotene and Irinotecan Drug Interactions
bexarotene and Irinotecan Drug Interactions. Drug-drug and drug-food interactions between ... In one study, irinotecan pharmacokinetics were determined ...
http://www.drugs.com/drug-interactions/bexarotene_d04507_irinotecan_d04026.html
www.drugs.com
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summary
S 1 (combination)(S-1) - NextBio
... carcinoma interferon-alpha irinotecan neutropenia non-small ... Phase I/II study of S-1 combined with irinotecan for metastatic advanced gastric cancer. ...
http://www.nextbio.com/b/home/home.nb?q=S-1
www.nextbio.com
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summary
Irinotecan plus fluorouracil and leucovorin for metastatic colorectal ...
Irinotecan prolongs survival in patients with colorectal cancer that is ... A third group of patients received irinotecan alone. ...
http://www.ncbi.nlm.nih.gov/pubmed/11006366
www.ncbi.nlm.nih.gov
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Drug Information for Fosphenytoin Inj - WebMD
Find medical information for Fosphenytoin Inj including side effects, drug interactions, ... Altered irinotecan metabolism in a patient receiving phenytoin. ...
http://www.webmd.com/drugs/drug-13896-Fosphenytoin+Inj.aspx?...
www.webmd.com
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summary
Camptosar Information from Drugs.com
Camptosar (irinotecan) is used to treat cancers of the colon and rectum. ... Irinotecan injection is available with a prescription under the brand name Camptosar. ...
http://www.drugs.com/camptosar.html
www.drugs.com
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summary
Colon cancer: Treatment - Health Professional Information [NCI PDQ ...
This PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based ... using an irinotecan-based regimen ...
http://health.yahoo.com/other-other/colon-cancer-treatment-h...
health.yahoo.com
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summary
Optical Imaging of Tumor Cells in Hollow Fibers: Evaluation of the ...
Irinotecan hydrochloride (Camptosar, 20 mg/ml; Pharmacia and Upjohn Co., New ... Synergistic effect of gemcitabine and irinotecan (CPT-11) on breast and small ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1950435
www.pubmedcentral.nih.gov
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Definition of irinotecan - NCI Dictionary of Cancer Terms
Irinotecan blocks certain enzymes needed for cell division and DNA repair, and ... irinotecan hydrochloride, iris, irofulven, iron, iron overload ...
http://www.nci.nih.gov/Templates/db_alpha.aspx?CdrID=45391
www.nci.nih.gov
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Gastrointestinal Cancer Models
Irinotecan (CPT-11, Camptosar) converts the normal nuclear enzyme, topoisomerase ... More recently, the combination of irinotecan, 5-FU, and leucovorin (IFL) has ...
http://emice.nci.nih.gov/mouse_models/organ_models/gastro_models
emice.nci.nih.gov
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Pharmacogenomics: When drug treatment becomes personalized medicine ...
Pharmacogenomics is a type of personalized medicine that studies how you ... how the body breaks down irinotecan (Camptosar), a chemotherapy drug used to ...
http://www.mayoclinic.com/health/personalized-medicine/CA00078
www.mayoclinic.com
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summary
Drugs A-Z List - C on RxList
Browse an A-Z list of Brand and Generic drugs to learn about your prescription medication. ... Camptosar Injection (Irinotecan Hydrochloride) Canasa (Mesalamine) ...
http://www.rxlist.com/drugs/alpha_c.htm
www.rxlist.com
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Treatment with 5-FU, Oxaliplatin, and Irinotecan Enables Resection of ...
Cancer research - journal article. Treatment with 5-FU, Oxaliplatin, and Irinotecan Enables Resection of Metastases in Patients with Initially Unresectable ...
http://coloncancer.about.com/od/journalarticlesfrom2006/a/2006Abstract22.htm
coloncancer.about.com
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Camptosar Official FDA information, side effects and uses.
Accurate, FDA approved Camptosar information for healthcare professionals ... Irinotecan serves as a water-soluble precursor of the lipophilic metabolite SN ...
http://www.drugs.com/pro/camptosar.html
www.drugs.com
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Role of cytokines (TNF-alpha, IL-1beta and KC) in the pathogenesis of ...
INTRODUCTION: Irinotecan (CPT-11) is an inhibitor of DNA topoisomerase I and is ... irinotecan. keratinocyte-derived chemokines. Thalidomide. Pentoxifylline ...
http://www.ncbi.nlm.nih.gov/pubmed/17624531?ordinalpos=76&it...
www.ncbi.nlm.nih.gov
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Drug Information for Atazanavir Oral - WebMD
Find medical information for Atazanavir Oral including side effects, drug interactions, images and pictures, ... ATAZANAVIR/IRINOTECAN. PROTEASE ...
http://www.webmd.com/drugs/drug-76254-Atazanavir+Oral.aspx?d...
www.webmd.com
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IFL chemotherapy - Wikipedia, the free encyclopedia
... of concurrent treatment with irinotecan, leucovorin (folinic acid), and ... Camptotheca (Camptothecin, Topotecan, Irinotecan, Rubitecan, Belotecan) II ...
http://en.wikipedia.org/wiki/IFL_chemotherapy
en.wikipedia.org
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Efficacy, safety, and cost of new anticancer drugs
... results from randomised trials of irinotecan and oxaliplatin (not considered by ... combination.2-2 2-3 Irinotecan and oxaliplatin are not even mentioned ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1124759
www.pubmedcentral.nih.gov
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NIGMS -- Findings, September 2002: Bench to Bedside
An online magazine that highlights two NIGMS-funded scientists who are doing ... reaction to a chemotherapy drug called irinotecan, which is used to treat a ...
http://publications.nigms.nih.gov/findings/sept02/bench.html
publications.nigms.nih.gov
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summary
Dilantin (Phenytoin) Drug Information: Uses, Side Effects, Drug ...
Learn about the prescription medication Dilantin (Phenytoin), drug uses, ... some drugs to treat cancer (e.g., imatinib, irinotecan), corticosteroids (e. ...
http://www.rxlist.com/dilantin-drug.htm
www.rxlist.com
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summary
Family 1 uridine-5'-diphosphate glucuronosyltransferases (UGT1A): from ...
... effects of the anticancer drug irinotecan and the antiviral proteinase inhibitor ... irinotecan. atazanavir. Bilirubin. Camptothecin ...
http://www.ncbi.nlm.nih.gov/pubmed/18491077
www.ncbi.nlm.nih.gov
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Erbitux ImClone - Treatment for Advanced Colorectal Cancer
Browse all medications A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ... intravenously with irinotecan, or alone if patients cannot tolerate irinotecan. ...
http://www.drugs.com/newdrugs/erbitux-imclone-advanced-color...
www.drugs.com
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Financial considerations in the conduct of multi-centre randomised ...
... survival times for irinotecan and oxaliplatin did not warrant the costs ... NICE issued guidelines recommending that irinotecan should be used only after ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1781076
www.pubmedcentral.nih.gov
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IRINOTECAN - INJECTION (Camptosar) side effects, medical uses, and drug ...
Read doctor-produced health and medical information written for you to make informed decisions about ... irinotecan-injection, camptosar index. irinotecan ...
http://www.medicinenet.com/irinotecan-injection/index.htm
www.medicinenet.com
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Colorectal Cancer-Medications
Information on medications for colorectal cancer. ... Capecitabine, sometimes combined with irinotecan or oxaliplatin. ... Irinotecan, sometimes combined with 5-FU. ...
http://www.webmd.com/colorectal-cancer/tc/colorectal-cancer-medications
www.webmd.com
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Modulation of irinotecan metabolism by ketoconazole.
PURPOSE: Irinotecan (CPT-11) is a prodrug of SN-38 and has been registered for ... the role of CYP3A4 in irinotecan pharmacology, we evaluated the consequences of ...
http://www.ncbi.nlm.nih.gov/pubmed/12118026?dopt=Abstract
www.ncbi.nlm.nih.gov
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