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imatinib mesylate
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what is 'imatinib mesylate'?
Definition for Imatinib mesylate
Imatinib is a drug used to treat certain types of cancer . It is currently marketed by Novartis as Gleevec ( USA ) or Glivec ( Europe / Australia ) as its mesylate salt, imatinib mesilate ( INN ).
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Imatinib is a drug used to treat certain types of cancer . It is currently marketed by Novartis as Gleevec ( USA ) or Glivec ( Europe / Australia ) as its mesylate salt, imatinib mesilate ( INN ). It was originally coded during development as CGP57148B or STI-571 (these terms are used in early preclinical publications). It is used in treating chronic myelogenous leukemia (CML), gastrointestinal stromal tumors (GISTs) and a number of other malignancies .
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diagnoses treated with 'imatinib mesylate'
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diagnosis
small intestine carcinoma
small bowel cancer
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Imatinib mesylate and small intestine carcinoma
acute lymphocytic leukemia
cancer of white blood cells
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Imatinib mesylate and acute lymphocytic leukemia
myelofibrosis
scarred bone marrow
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Imatinib mesylate and myelofibrosis
related procedures when taking 'imatinib mesylate'
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105
procedures
Abdominal CAT Scan
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Imatinib mesylate and Abdominal CAT Scan
Blood, Platelet Count
Platelet Count
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Imatinib mesylate and Blood, Platelet Count
Complete Blood Count
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Imatinib mesylate and Complete Blood Count
Biopsy
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Imatinib mesylate and Biopsy
Biopsy small bowel
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Imatinib mesylate and Biopsy small bowel
Capsule endoscopy
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Imatinib mesylate and Capsule endoscopy
Carcinoembryonic Antigen (CEA)
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Imatinib mesylate and Carcinoembryonic Antigen (CEA)
Colonoscopy
Colonoscopy
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Imatinib mesylate and Colonoscopy
Colonoscopy with retrograde ileoscopy
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Imatinib mesylate and Colonoscopy with retrograde ileoscopy
Double-contrast barium enema
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Imatinib mesylate and Double-contrast barium enema
Endoscopic ultrasonography
Endoscopic Ultrasound
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Imatinib mesylate and Endoscopic ultrasonography
Endoscopy
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Imatinib mesylate and Endoscopy
Endoscopy, Upper Gastrointestinal
Endoscopy
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Imatinib mesylate and Endoscopy, Upper Gastrointestinal
Enteroclysis
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Imatinib mesylate and Enteroclysis
KUB
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Imatinib mesylate and KUB
Liver Function Tests
elevated liver enzymes
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Imatinib mesylate and Liver Function Tests
Pancreaticoduodenectomy (Whipple procedure)
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Imatinib mesylate and Pancreaticoduodenectomy (Whipple procedure)
Partial Resection of Intestine with Anastomosis
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Imatinib mesylate and Partial Resection of Intestine with Anastomosis
Pill camera
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Imatinib mesylate and Pill camera
Resection
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Imatinib mesylate and Resection
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related medication for 'imatinib mesylate'
1 - 5 of
39
drugs
fluorouracil
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Imatinib mesylate and fluorouracil
irinotecan
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Imatinib mesylate and irinotecan
leucovorin
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Imatinib mesylate and leucovorin
oxaliplatin
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Imatinib mesylate and oxaliplatin
sunitinib
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Imatinib mesylate and sunitinib
prednisone
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Imatinib mesylate and prednisone
6-mercaptopurine (6-mp), epipodophyllotoxins
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Imatinib mesylate and 6-mercaptopurine (6-mp), epipodophyllotoxins
allopurinol
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Imatinib mesylate and allopurinol
anthracycline
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Imatinib mesylate and anthracycline
asparaginase
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Imatinib mesylate and asparaginase
asparaginase(elspar )
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Imatinib mesylate and asparaginase(elspar )
clofarabine
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Imatinib mesylate and clofarabine
clotrimazole troches
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Imatinib mesylate and clotrimazole troches
cyclophosphamide(cytoxan)
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Imatinib mesylate and cyclophosphamide(cytoxan)
cytarabine
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Imatinib mesylate and cytarabine
cytarabine(cytosar-u , tarabine pfs)
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Imatinib mesylate and cytarabine(cytosar-u , tarabine pfs)
dasatinib(sprycel )
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Imatinib mesylate and dasatinib(sprycel )
daunorubicin
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Imatinib mesylate and daunorubicin
daunorubicin(cerubidine , daunorubicin hydrochloride)
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Imatinib mesylate and daunorubicin(cerubidine , daunorubicin hydrochloride)
dexamethasone
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Imatinib mesylate and dexamethasone
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web search results for 'imatinib mesylate'?
Results
1 - 50
- Imatinib mesylate
Imatinib - Wikipedia, the free encyclopedia
One study demonstrated that Imatinib mesylate was effective in patients with ... Imatinib mesylate in the treatment of systemic mastocytosis: a phase II trial. ...
http://en.wikipedia.org/wiki/Imatinib_mesylate
en.wikipedia.org
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summary
Gleevec (Imatinib Mesylate) Drug Information: Uses, Side Effects, Drug ...
Learn about the prescription medication Gleevec (Imatinib Mesylate), drug uses, dosage, side effects, drug interactions, warnings, and patient labeling.
http://www.rxlist.com/cgi/generic3/gleevec.htm
www.rxlist.com
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summary
Imatinib mesylate
Drug details for Imatinib mesylate. ... myeloid leukemia treated with imatinib mesylate. ... Cardiotoxicity of the cancer therapeutic agent imatinib mesylate. ...
http://www.webmd.com/cancer/imatinib-mesylate
www.webmd.com
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Imatinib Mesylate Drug Information, Professional
Imatinib Mesylate Drug Information from Drugs.com. Includes Imatinib Mesylate side effects, interactions and indications. ... IMATINIB MESYLATE CAPSULES ...
http://www.drugs.com/mmx/imatinib-mesylate.html
www.drugs.com
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summary
Imatinib mesylate - Yahoo! Health
Imatinib is available as capsules you ... with chronic myeloid leukemia treated with imatinib mesylate. ... of the cancer therapeutic agent imatinib mesylate. ...
http://health.yahoo.com/other-other/imatinib-mesylate/healthwise--tv7950.html
health.yahoo.com
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summary
Treatment of gastrointestinal stromal tumor: focus on imatinib mesylate
Pharmacology of imatinib mesylate. Preclinical studies of imatinib ... as it is one of the targets of the tyrosine kinase inhibitor imatinib mesylate. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2503651
www.pubmedcentral.nih.gov
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MedlinePlus Drug Information: Imatinib
Imatinib ... Imatinib is used to treat certain types of leukemia (cancer that begins in the ... if you are allergic to imatinib or any other medications. ...
http://www.nlm.nih.gov/medlineplus/druginfo/meds/a606018.html
www.nlm.nih.gov
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Imatinib: Drug Information Provided by Lexi-Comp: Merck Manual Professional
... R, et al, "Adjuvant Imatinib Mesylate Increases Recurrence Free Survival (RFS) ... and Pharmacokinetic Study of Imatinib Mesylate in Patients With Advanced ...
http://www.merck.com/mmpe/lexicomp/imatinib.html
www.merck.com
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Definition of imatinib mesylate - NCI Dictionary of Cancer Terms
Report to Nation Finds Declines in ... imatinib mesylate (ih-MAH-tih-nib MEH-zih-layt) ... Imatinib mesylate blocks the protein made by the bcr/abl oncogene. ...
http://www.nci.nih.gov/Templates/db_alpha.aspx?CdrID=44893
www.nci.nih.gov
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Control of aggressive fibromatosis by treatment with imatinib mesylate ...
... the number of kinases blocked by imatinib mesylate is notching up, for instance ... CONCLUSIONS: Treatment with imatinib mesylate has been a well-accepted therapy ...
http://www.ncbi.nlm.nih.gov/pubmed/17453242
www.ncbi.nlm.nih.gov
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summary
IMATINIB - ORAL (Gleevec) side effects, medical uses, and drug interactions.
Read more about the prescription drug IMATINIB - ORAL. ... USES: Imatinib is used to treat a type of leukemia (chronic myeloid leukemia or ...
http://www.medicinenet.com/imatinib-oral/article.htm
www.medicinenet.com
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summary
Comparison of imatinib mesylate, dasatinib (BMS-354825), and nilotinib ...
Imatinib mesylate (Gleevec, STI571) has become the standard of care for the ... Inhibitor concentrations were as follows: imatinib mesylate, 2 ?M, 4 ?M, 8 ?M, ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pub...
www.pubmedcentral.nih.gov
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Mesylate - Wikipedia, the free encyclopedia
In chemistry, a mesylate is any salt or ester of methanesulfonic acid (C ... spelling is mesilate (as in imatinib mesilate, the mesylate salt of imatinib).[1] ...
http://en.wikipedia.org/wiki/Mesylate
en.wikipedia.org
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summary
Imatinib facts and comparsions at Drugs.com
All about Imatinib. View complete and up to date Imatinib information - part of the Drugs.com trusted medication database. ... a dose of Imatinib , take it as ...
http://www.drugs.com/cdi/imatinib.html
www.drugs.com
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summary
Clinical Study: 02-I-0286, A Pilot Study of the Safety and Efficacy of ...
Clinical Study Summary Sheet for 02-I-0286 ... Imatinib mesylate will be initiated at a dose of 400 mg daily, the FDA-approved ...
http://clinicalstudies.info.nih.gov/detail/A_2002-I-0286.html
clinicalstudies.info.nih.gov
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summary
Chronic Myelogenous Leukemia
Higher doses of imatinib mesylate, alternative tyrosine kinase inhibitors such ... What is the best dose of imatinib mesylate and should it be combined with other ...
http://www.webmd.com/cancer/tc/leukemia-chronic-myelogenous-...
www.webmd.com
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summary
National Biospecimen Network
Imatinib mesylate (STI-571, Gleevec®; Novartis, Basel, Switzerland), a small ... Clinical use of imatinib mesylate in patients with GIST proved dramatic, as 60 ...
http://prostatenbnpilot.nci.nih.gov/blue_app_b.asp
prostatenbnpilot.nci.nih.gov
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Imatinib mesylate causes hypopigmentation in the skin.
In clinical trials with imatinib mesylate, common side effects of nausea, emesis, ... Imatinib mesylate induced hypopigmentation also appeared to be reversible and ...
http://www.ncbi.nlm.nih.gov/pubmed/14635084
www.ncbi.nlm.nih.gov
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summary
Synergistic interactions between imatinib mesylate and the novel ...
... by which E255K and T315I affect imatinib mesylate's interactions with the ... Conceivably, this mutation affects imatinib mesylate binding by altering the ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1895085
www.pubmedcentral.nih.gov
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Imatinib mesylate enhances therapeutic effects of gemcitabine in human ...
Imatinib mesylate (STI571; Glivec) is a selective inhibitor of tyrosine kinases ... We previously showed that imatinib mesylate synergizes with gemcitabine and ...
http://www.ncbi.nlm.nih.gov/pubmed/18223230
www.ncbi.nlm.nih.gov
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The role of c-kit and imatinib mesylate in uveal melanoma
Imatinib mesylate is a FDA approved compound that inhibits tyrosine quinase ... Imatinib mesylate controls tumor growth in up to 85% of advanced ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pub...
www.pubmedcentral.nih.gov
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Talk:Imatinib - Wikipedia, the free encyclopedia
... move this page to the INN Imatinib mesylate. ... INN is Imatinib mesilate, not mesylate. ... The Novartis documentation refers to it as 'imatinib mesylate' ...
http://en.wikipedia.org/wiki/Talk:Imatinib
en.wikipedia.org
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imatinib - PubChem Public Chemical Database
PubChem Compound Summary ... contain imatinib mesylate equivalent to 100mg or 400 mg of imatinib free base. Imatinib mesylate is designated chemically as ...
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=5291
pubchem.ncbi.nlm.nih.gov
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PD166326, a novel tyrosine kinase inhibitor, has greater antileukemic ...
Imatinib mesylate is highly effective in newly diagnosed chronic myeloid ... Imatinib mesylate had a complete cytogenetic response rate of 13% to 24% in ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1895078
www.pubmedcentral.nih.gov
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Imatinib mesylate in the treatment of systemic mastocytosis: a phase II ...
Imatinib mesylate is a potent inhibitor of c-kit receptor tyrosine kinase activity. ... In general, imatinib mesylate was tolerated well. ...
http://www.ncbi.nlm.nih.gov/pubmed/16779792
www.ncbi.nlm.nih.gov
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summary
Drug Information for Imatinib Oral - WebMD
Find medical information for Imatinib Oral including side effects, drug interactions, images and pictures, medication ... to Imatinib Mesylate Oral. Consumer ...
http://www.webmd.com/drugs/drug-20983-Imatinib+Mesylate+Oral...
www.webmd.com
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summary
Therapeutic options for chronic myeloid leukemia: focus on imatinib ...
Imatinib mesylate (Glivec®/Gleevec?) Results in chronic phase CML. Treatment strategies 2007 ... molecule inhibitor imatinib mesylate (Glivec®, Gleevec? ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2503652
www.pubmedcentral.nih.gov
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Definition of imatinib mesylate - National Cancer Institute Drug Dictionary
imatinib mesylate. The mesylate salt of imatinib, a tyrosine kinase inhibitor with antineoplastic ... Imatinib binds to an intracellular pocket located within ...
http://www.nci.nih.gov/Templates/drugdictionary.aspx?CdrID=37862
www.nci.nih.gov
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summary
Hypopigmentation in an African patient treated with imatinib mesylate ...
Imatinib mesylate (STI 571, Gleevec) is a potent bcr-abl tyrosine kinase inhibitor. ... in patients receiving imatinib mesylate for CML has been ...
http://www.ncbi.nlm.nih.gov/pubmed/12934870?ordinalpos=146&i...
www.ncbi.nlm.nih.gov
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summary
Population pharmacokinetics of imatinib mesylate in patients with ...
Population pharmacokinetics of imatinib mesylate in patients with chronic-phase ... Imatinib mesylate (Gleevec®, Glivec®, formerly STI571; Novartis Pharma AG, Basel, ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1884912
www.pubmedcentral.nih.gov
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BCR-ABL mRNA levels at and after the time of a complete cytogenetic ...
Imatinib mesylate induces a complete hematologic response in approximately 97 ... In patients treated with imatinib mesylate who were resistant or intolerant of ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1895785
www.pubmedcentral.nih.gov
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cml gleevec prognosis
Imatinib mesylate (STI-571, Gleevec) and reduced intensity conditioning stem ... assessing the role of imatinib mesylate and RIC transplantation should be ...
http://www.ncbi.nlm.nih.gov/pubmed/15382266
www.ncbi.nlm.nih.gov
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Activation mutations of human c-KIT resistant to imatinib mesylate are ...
Variable sensitivities to PKC412 or imatinib mesylate were observed among other mutants. ... have suggested that imatinib mesylate might be of value ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1895184
www.pubmedcentral.nih.gov
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Approval summary: imatinib mesylate in the treatment of metastatic and ...
PURPOSE: Imatinib mesylate (Gleevec; Novartis, East Hanover, NJ)is a receptor ... CONCLUSIONS: On February 1, 2001, imatinib mesylate was approved by the United ...
http://www.ncbi.nlm.nih.gov/pubmed/12374669
www.ncbi.nlm.nih.gov
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Selective tyrosine kinase inhibition by imatinib mesylate for the ...
Cell lines, antibodies, and imatinib mesylate. ... Imatinib mesylate tablets (purchased from Stanford Inpatient Pharmacy Services) ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pub...
www.pubmedcentral.nih.gov
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gleevec treatment gist
... 6667 63 5 2003 Drugs Imatinib mesylate: in the treatment of gastrointestinal ... One such drug is imatinib mesylate (imatinib, Glivic/Gleevec), an orally ...
http://www.ncbi.nlm.nih.gov/pubmed/12600228
www.ncbi.nlm.nih.gov
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The Merendino procedure following preoperative imatinib mesylate for ...
Imatinib mesylate is a selective small molecule receptor inhibitor of tyrosine ... After pre-treatment with imatinib mesylate and relevant tumor shrinkage ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2323006
www.pubmedcentral.nih.gov
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summary
Relative Hypocalcaemia and Muscle Cramps in Patients Receiving Imatinib ...
Imatinib mesylate is a tyrosine kinase inhibitor targeted to BCR-ABL, PDGFR, and ... extensive abdominal GIST commenced imatinib mesylate (Glivec, Novartis) 400 mg ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1557796
www.pubmedcentral.nih.gov
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Efficacy of imatinib mesylate in the treatment of refractory ...
Efficacy of imatinib mesylate in the treatment of refractory ... Imatinib mesylate enables selective, dual inhibition of the transforming growth ...
http://www.ncbi.nlm.nih.gov/pubmed/18762765
www.ncbi.nlm.nih.gov
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Advanced gastrointestinal stromal tumors successfully treated with ...
Imatinib mesylate (STI 571,Gleevec) is a selective inhibitor of certain protein ... Imatinib mesylate induced a sustained response in both patients with advanced ...
http://www.ncbi.nlm.nih.gov/pubmed/14717479?ordinalpos=96&it...
www.ncbi.nlm.nih.gov
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Molecular response of gastrointestinal stromal tumour after treatment ...
Imatinib mesylate (STI571), a small molecule tyrosine kinase inhibitor, is a ... Imatinib mesylate has changed the treatment of metastatic GISTs completely. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1770203
www.pubmedcentral.nih.gov
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Surgery of Residual Disease Following Molecular-targeted Therapy With ...
... were treated with imatinib mesylate at a single ... Casali PG, Fumagalli E, Messina A, et al. Tumor response to imatinib mesylate in advanced GIST. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1877023
www.pubmedcentral.nih.gov
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Treatment of Philadelphia chromosome-positive acute lymphocytic ...
Imatinib mesylate, an inhibitor of the Bcr-Abl tyrosine kinase, has modest ... Outcome with hyper-CVAD and imatinib mesylate appears better than with prior ...
http://www.ncbi.nlm.nih.gov/pubmed/14551133
www.ncbi.nlm.nih.gov
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Metastatic duodenal GIST: role of surgery combined with imatinib mesylate
Imatinib mesylate, a specific tyrosine kinase inhibitor, is one of the first ... Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1851968
www.pubmedcentral.nih.gov
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Imatinib mesylate dose escalation is associated with durable responses ...
Imatinib mesylate dose escalation is associated with durable responses in ... In conclusion, imatinib dose escalation can induce sustained responses in a ...
http://www.ncbi.nlm.nih.gov/pubmed/19060245?dopt=abstractplus
www.ncbi.nlm.nih.gov
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summary
The small molecule tyrosine kinase inhibitor AMN107 inhibits TEL-PDGFR? ...
The imatinib mesylate?resistant mutant TEL-PDGFR? T681I was sensitive to AMN107, ... However, clinical resistance to imatinib mesylate is emerging as an important ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pub...
www.pubmedcentral.nih.gov
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Hematologic and cytogenetic responses to imatinib mesylate in chronic ...
... and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia. ... Imatinib mesylate, formerly STI571, is a selective inhibitor of this kinase. ...
http://www.ncbi.nlm.nih.gov/pubmed/11870241
www.ncbi.nlm.nih.gov
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Combined Surgical and Molecular Therapy
Imatinib mesylate (STI 571, Gleevec; Novartis Pharmaceuticals, Basel Switzerland) ... Trials of Imatinib Mesylate in Metastatic GIST ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1602162
www.pubmedcentral.nih.gov
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Imatinib mesylate selectively impairs expansion of memory cytotoxic T ...
Imatinib mesylate selectively impairs expansion of memory cytotoxic T cells ... Imatinib mesylate (imatinib) is a potent inhibitor of defined tyrosine kinases ...
http://www.ncbi.nlm.nih.gov/pubmed/16873671?ordinalpos=7&ito...
www.ncbi.nlm.nih.gov
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Large duodenal GIST with massive liver secondaries melting under ...
The phenomenon of metastatic GIST responding to Imatinib mesylate is not new. ... Imatinib mesylate, a specific tyrosikine kinase inhibitor has produced a ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2570680
www.pubmedcentral.nih.gov
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