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bcnu
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what is 'bcnu'?
Definition for BCNU
Carmustine or BCNU (= "bis-chloronitrosourea") is a mustard gas -related ?-chloro- nitrosourea compound used as an alkylating agent in chemotherapy .
Carmustine for injection is marketed under the name BiCNU by Bristol-Myers Squibb.
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Carmustine or BCNU (= "bis-chloronitrosourea") is a mustard gas -related ?-chloro- nitrosourea compound used as an alkylating agent in chemotherapy .
Carmustine for injection is marketed under the name BiCNU by Bristol-Myers Squibb.
It is used in the treatment of several types of brain cancer (including glioma , glioblastoma multiforme , medulloblastoma and astrocytoma ), multiple myeloma and lymphoma ( Hodgkin's and non-Hodgkin ).
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diagnoses treated with 'bcnu'
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1
diagnosis
Hodgkin's lymphoma
type of cancer of the lymphatic system-lymphoma
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BCNU and Hodgkin's lymphoma
related procedures when taking 'bcnu'
1 - 5 of
61
procedures
Abdominal CAT Scan
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BCNU and Abdominal CAT Scan
Biopsy
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BCNU and Biopsy
Biopsy bone marrow
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BCNU and Biopsy bone marrow
Biopsy small bowel
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BCNU and Biopsy small bowel
Bone Marrow Transplant
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BCNU and Bone Marrow Transplant
Brain MRI
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BCNU and Brain MRI
CT Pelvis
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BCNU and CT Pelvis
CT chest
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BCNU and CT chest
CT scan
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BCNU and CT scan
CT spleen
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BCNU and CT spleen
Cerebrospinal Fluid eosinophils
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BCNU and Cerebrospinal Fluid eosinophils
Cervical mediastinoscopy
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BCNU and Cervical mediastinoscopy
Complete Blood Count
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BCNU and Complete Blood Count
Complete metabolic panel
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BCNU and Complete metabolic panel
Coombs test
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BCNU and Coombs test
Cytodiagnosis
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BCNU and Cytodiagnosis
Cytokine Assay
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BCNU and Cytokine Assay
Delayed hypersensitivity skin testing
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BCNU and Delayed hypersensitivity skin testing
Erythrocyte Sedimentation Rate (ESR)
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BCNU and Erythrocyte Sedimentation Rate (ESR)
FDG PET scan
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BCNU and FDG PET scan
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related medication for 'bcnu'
1 - 5 of
20
drugs
adriamycin
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BCNU and adriamycin
bleomycin(blenoxane )
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BCNU and bleomycin(blenoxane )
carboplatin
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BCNU and carboplatin
cisplatin
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BCNU and cisplatin
cytarabine
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BCNU and cytarabine
dacarbazine(dtic-dome )
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BCNU and dacarbazine(dtic-dome )
dexamethasone
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BCNU and dexamethasone
doxorubicin(adriamycin)
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BCNU and doxorubicin(adriamycin)
etoposide
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BCNU and etoposide
ifosfamide
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BCNU and ifosfamide
mechlorethamine(mustargen )
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BCNU and mechlorethamine(mustargen )
melphalan
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BCNU and melphalan
mesna
web search for:
BCNU and mesna
methotrexate(trexall)
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BCNU and methotrexate(trexall)
prednisone(deltasone)
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BCNU and prednisone(deltasone)
procarbazine(matulane )
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BCNU and procarbazine(matulane )
radiation therapy
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BCNU and radiation therapy
vinblastine
web search for:
BCNU and vinblastine
vinblastine(vinblastine sulfate , velban)
web search for:
BCNU and vinblastine(vinblastine sulfate , velban)
vincristine(oncovin)
web search for:
BCNU and vincristine(oncovin)
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The following are types of physicians relevant for 'BCNU'.
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web search results for 'bcnu'?
Results
1 - 50
- BCNU
Carmustine - Wikipedia, the free encyclopedia
Carmustine. From Wikipedia, the free encyclopedia. Jump to: navigation, ... Carmustine or BCNU is a mustard gas-related ?-chloro-nitrosourea compound used ...
http://en.wikipedia.org/wiki/Carmustine
en.wikipedia.org
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summary
CARMUSTINE (BCNU)
Information for CARMUSTINE (BCNU) on Drugs.com. May include images, interactions and related content. ... Carmustine Or Bcnu Chemotherapy Regimen. Get the ...
http://www.drugs.com/search.php?is_main_search=1&searchterm=CARMUSTINE+(BCNU)
www.drugs.com
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summary
Levels and distribution of BCNU in GBM tumors following intratumoral ...
... 1-nitrosourea (3H-BCNU) were identified and quantified. ... Keywords: BCNU, carmustine, DTI-015, ethanol, glioblastoma multiforme, ... of BCNU with ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1828109
www.pubmedcentral.nih.gov
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summary
BCNU toxicity presenting with a large pericardial ...[Ann Transplant ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and other life science journals for biomedical ...
http://www.ncbi.nlm.nih.gov/pubmed/18344943
www.ncbi.nlm.nih.gov
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summary
BCNU (bis chloroethylnitrosourea)
Prev Term: BCNU. Next Term: BCSFB (blood cerebrospinal fluid barrier) BCNU (bis chloroethylnitrosourea) Use: carmustine. Send your comments to: Melody Lowe ...
http://crisp.cit.nih.gov/Thesaurus/00010208.htm
crisp.cit.nih.gov
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summary
Phase 2 study of BCNU and temozolomide for recurrent glioblastoma ...
BCNU has been used for both newly diagnosed and recurrent malignant glioma, with ... BCNU forms a chloroethyl adduct at the O6 position of guanine, whereas ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1871975
www.pubmedcentral.nih.gov
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summary
BCNU
Close Print this page. BCNU. Synonym(s): carmustine ...
http://www.drugs.com/dict/bcnu.html?printable=1
www.drugs.com
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summary
Drug delivery: Engineering new methods for disease prevention and treatment
Intracranial BCNU-loaded polymer implants. increase survival in brain tumors ... Concentration of BCNU in vicinity of polymer implant: Sustained levels in the ...
http://www.ninds.nih.gov/funding/research/epilepsyweb/curing...
www.ninds.nih.gov
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summary
A phase 3 trial of local chemotherapy with biodegr...[Neuro Oncol. 2003 ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE ... carmustine (BCNU) implants in ...
http://www.ncbi.nlm.nih.gov/pubmed/12672279
www.ncbi.nlm.nih.gov
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summary
PCNU
It is less lipid soluble than BCNU or CCNU but its lipid solubility is in the range which ... Other abbreviations used are BCNU = 1, 3-bis(2-chloroethyl)-1 ...
http://dohs.ors.od.nih.gov/pdf/PCNU%20re-REVISED.pdf
dohs.ors.od.nih.gov
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summary
11th ROC: bis(Chloroethyl) nitrosourea
bis(Chloroethyl) nitrosourea (BCNU) is reasonably anticipated to be a. human carcinogen based on suf?cient evidence of carcinogenicity in ...
http://ntp.niehs.nih.gov/ntp/roc/eleventh/profiles/s037bcnu.pdf
ntp.niehs.nih.gov
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summary
Phase 1 trial of irinotecan plus BCNU in patients with progressive or ...
BCNU was administered at a dose of 100 mg/m2 over 1 h every 6 weeks on the same ... Although BCNU, a contraction of the chemical name 1,3-bis(2-chloroethyl)-1 ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1871988
www.pubmedcentral.nih.gov
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summary
Mycosis Fungoides and the Sézary Syndrome
... Topical chemotherapy with mechlorethamine (nitrogen mustard) or carmustine (BCNU) ... WebMD Home Cancer Health Center Cancer Related Topics. Email a Friend ...
http://www.webmd.com/cancer/tc/mycosis-fungoides-and-the-sez...
www.webmd.com
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summary
Increased oxidative stress created by adenoviral M...[Free Radic Biol ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... adenovirusMnSOD plus BCNU treatment. ...
http://www.ncbi.nlm.nih.gov/pubmed/18155673
www.ncbi.nlm.nih.gov
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summary
NIH-OTT Featured Technology (November 2006)
The NIH Office of Technology Transfer (OTT) evaluates, protects, monitors, and manages the NIH invention portfolio ... 1-nitrosourea (BCNU) and the methylating ...
http://ott.od.nih.gov/db/abstxt57.html
ott.od.nih.gov
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summary
Phase 2 trial of BCNU plus irinotecan in adults with malignant glioma
In the current study, BCNU (100 mg/m2) was administered on day 1 of each 6-week cycle. ... Nitrosoureas including CCNU (lomustine) and BCNU (1,3-bis(2-chloroethyl)-1 ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1871982
www.pubmedcentral.nih.gov
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summary
List of IARC Group 2A carcinogens - Wikipedia, the free encyclopedia
Substances, mixtures and exposure circumstances in this list have been ... BCNU (Bischloroethyl nitrosourea) 1,3-Butadiene. Captafol. Chloramphenicol ...
http://en.wikipedia.org/wiki/List_of_IARC_Group_2A_carcinogens
en.wikipedia.org
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summary
4. INTRODUCTION 4.1. Investigational Plan
Carmustine (BCNU) 122. 22(18) 11-25. Lomustine (CCNU) 270. 35(13) 9-17 ... DTIC+BCNU+TAM ... CDDP, BCNU and Tamoxifen and has been reported to have a 50 ...
http://www4.od.nih.gov/oba/rac/abstracts/234_s.pdf
www4.od.nih.gov
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summary
THE
6-, 12-, 18- & 24-month survival estimates in included BCNU-W studies - GBM only . Selected postoperative complications in BCNU-W RCT and other reported ...
http://www.nice.org.uk/nicemedia/pdf/Glioma_Assessment_Report.pdf
www.nice.org.uk
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summary
Phase 1 study of 28-day, low-dose temozolomide and BCNU in the ...
We conclude that the combination of BCNU and the extended dosing schedule of TMZ ... Dose reduction to 125 mg/m2 of BCNU occurred in cycle 2 for four patients and ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1871994
www.pubmedcentral.nih.gov
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summary
Adult Brain Tumors
Note: Some citations in the text of this section are followed by a level of evidence. ... BCNU-impregnated polymer (Gliadel wafer) implanted during initial surgery. ...
http://www.webmd.com/cancer/brain-cancer/tc/brain-tumors-adu...
www.webmd.com
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summary
eMedicine - Drug-Induced Pulmonary Toxicity : Article by Arshad Ali
More than 380 medications are known to cause drug-induced respiratory diseases. ... Nitrosourea (BCNU, carmustine) ... BCNU causes pulmonary toxicity more ...
http://www.emedicine.com/med/topic1343451.htm
www.emedicine.com
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summary
DTP - Anti-cancer Agents by Mechanism
DTP Human Tumor Cell Line Screen. Anti-cancer Agents by ... BCNU. NSC 409962. Busulfan. NSC 750. carboxyphthalatoplatinum. NSC 271674. CBDCA. NSC 241240 ...
http://dtp.nci.nih.gov/docs/cancer/searches/standard_mechanism_list.html
dtp.nci.nih.gov
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summary
CNS progenitor cells and oligodendrocytes are targets of ...
Clinically relevant concentrations of BCNU or cisplatin were more toxic for ... Exposure to 5 ?M BCNU was also toxic for O-2A/OPCs, NRP cells, and oligodendrocytes. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pub...
www.pubmedcentral.nih.gov
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DTI-015 Produces Cures in T9 Gliosarcoma
DTI-015 (BCNU in 100% ethanol) utilizes solvent-facilitated perfusion for the ... Intravenously administered BCNU (carmustine) has been one of the leading ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1502128
www.pubmedcentral.nih.gov
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summary
CBV (chemotherapy) - Wikipedia, the free encyclopedia
... refers to Cytoxan (cyclophosphamide), BCNU (carmustine), and VP-16 (etoposide) ... CBV is usually given in high doses to patients who have relapsed or who have ...
http://en.wikipedia.org/wiki/CBV_(chemotherapy)
en.wikipedia.org
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summary
Brain Tumors: Primary
Carmustine (also called BCNU). Carmustine is known as a nitrosourea. ... with standard chemotherapy drugs, such as BCNU, is proving to be effective for some patients. ...
http://adam.about.com/reports/000089_10.htm
adam.about.com
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summary
GEO Accession viewer
NCBI's Gene Expression Omnibus (GEO) is a public archive and ... array-CGH MER-BCNU. Sample type. genomic. Channel 1. Source Name. Cy3: female reference ...
http://www.ncbi.nlm.nih.gov/projects/geo/query/acc.cgi?acc=GSM40640
www.ncbi.nlm.nih.gov
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methyl-CCNU
Close Print this page. methyl-CCNU. Pronunciation: meth?il ... antineoplastic agent resembling carmustine (BCNU) and lomustine (CCNU). Synonym(s): semustine ...
http://www.drugs.com/dict/methyl-ccnu.html?printable=1
www.drugs.com
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summary
Contributions of cell kill and posttreatment tumor growth rates to the ...
BCNU is a mainstay of brain tumor chemotherapy, but the clinical outcome of ... After BCNU treatment, peritumoral edema was observed in T2-weighted images (Fig. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=22721
www.pubmedcentral.nih.gov
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summary
Adult Brain Tumors
Anaplastic astrocytomas (World Health Organization grade III) have a low cure ... Carmustine (BCNU)-impregnated polymer may be implanted during surgery.[13,14] ...
http://www.webmd.com/cancer/brain-cancer/tc/brain-tumors-adu...
www.webmd.com
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summary
Retroviral transduction of a mutant methylguanine DNA methyltransferase ...
BCNU treatment of transplanted mice increased the proportion of hematopoietic ... Although MGMT overexpression increases BCNU resistance in normal murine and ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=19499
www.pubmedcentral.nih.gov
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eMedicine - Parapsoriasis : Article by Henry K Wong
Parapsoriasis describes a group of cutaneous diseases that can be characterized by scaly patches or slightly elevated ... Bischloroethylnitrosourea (BCNU) is ...
http://emedicine.com/derm/topic311.htm
emedicine.com
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summary
Stereotactic Injection of DTI-015 into Recurrent Malignant Gliomas ...
DTI-015 (BCNU in 100% ethanol) utilizes solvent facilitated perfusion for the ... BCNU has been delivered using intraarterial administration in an attempt to ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1502123
www.pubmedcentral.nih.gov
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summary
Safety and efficacy of permanent iodine-125 seed i...[J Neurosurg. 2008 ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... with carmustine (BCNU) wafers or ...
http://www.ncbi.nlm.nih.gov/pubmed/18240917?ordinalpos=1&ito...
www.ncbi.nlm.nih.gov
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National Cooperative Drug Discovery Group (NCDDG) Program
BCNU for Brain Tumors. Principal Investigators. ? Henry Brem, Johns Hopkins ... BCNU increased median survival in recurrent glioblastoma from. 11.6 to 13.9 months. ...
http://dtp.nci.nih.gov/timeline/posters/NCDDG.pdf
dtp.nci.nih.gov
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summary
carmustine
Close Print this page. carmustine. Pronunciation: kar-m?s?t?n. An antineoplastic agent. Synonym(s): BCNU ...
http://www.drugs.com/dict/carmustine.html?printable=1
www.drugs.com
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summary
In vivo selection of MGMT(P140K) lentivirus?transduced human NOD/SCID ...
Rounds of BG/BCNU treatment selected for human MGMT(P140K)?transduced SRCs over ... As shown in Figure 2 a, BG/BCNU treatment led to a small, 18% decrease in bone ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?&artid=259124
www.pubmedcentral.nih.gov
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summary
Applied molecular evolution of O6-benzylguanine-resistant DNA ...
BG currently is in clinical trials for combination use with BCNU (15) ... BG and BCNU Selection of Random Mutants. ... were treated with 50 ?M BG plus BCNU. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=33144
www.pubmedcentral.nih.gov
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Melanoma
Note: Some citations in the text of this section are followed by a level ... (DTIC) and the nitrosoureas, carmustine (BCNU) and lomustine, is approximately 10 ...
http://www.webmd.com/melanoma-skin-cancer/tc/melanoma-cutane...
www.webmd.com
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summary
nitrosourea
Close Print this page. nitrosourea. Pronunciation: n?-tr??s?-?r??-?. Alkylating agent used in the treatment of many neoplasms; an example is BCNU. ...
http://www.drugs.com/dict/nitrosourea.html?printable=1
www.drugs.com
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summary
ChemIDPlus/HSDB 154-93-8 Chemical - National Toxicology Program
Names (NTP) BCNU. 1,3-bis(Chloroethyl)-1-nitrosourea. NSC 409962. Structure ... BCNU. BiCNU. Bischloroethylnitrosourea. N,N'-Bis(2-chloroethyl)-N-nitrosourea ...
http://ntp.niehs.nih.gov/index.cfm?objectid=E87E0198-BDB5-82F8-F78784BAFEF0B752
ntp.niehs.nih.gov
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summary
Low electric field enhanced chemotherapy can cure mice with CT-26 colon ...
... LEFCT-EC with carmustine (BCNU). The third cytotoxic agent employed was BCNU. ... As shown in Fig. 1, BCNU alone or LEFCT alone failed to cure TB mice, although ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1809245
www.pubmedcentral.nih.gov
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Human Dkk-1, a gene encoding a Wnt antagonist, res...[Oncogene. 2002 ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... linking drugs BCNU and cisplatin, but ...
http://www.ncbi.nlm.nih.gov/pubmed/11840333
www.ncbi.nlm.nih.gov
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summary
Chemotherapy regimens - Wikipedia, the free encyclopedia
Chemotherapy regimens are often identified with acronyms, identifying the agents ... Cyclophosphamide, BCNU (carmustine), VP-16 (etoposide) Lymphoma. ChlVPP/EVA ...
http://en.wikipedia.org/wiki/Chemotherapy_regimens
en.wikipedia.org
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summary
Methylguanine methyltransferase?mediated in vivo selection and ...
BCNU produces profound hematopoietic stem cell toxicity, a prerequisite for ... O6BG/BCNU. ... Of note, a higher dose of BCNU (50 ?M) paradoxically led to a ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=259127
www.pubmedcentral.nih.gov
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summary
BCSFB (blood cerebrospinal fluid barrier)
Prev Term: BCNU (bis chloroethylnitrosourea) Next Term: BDNF. BCSFB (blood cerebrospinal fluid barrier) Use: blood brain barrier ...
http://crisp.cit.nih.gov/Thesaurus/00021143.htm
crisp.cit.nih.gov
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summary
Correlation distance (1-r) Euclidian distance on correlation coefficient
A6: Carmustine (BCNU) -A6: Lomustine (CCNU) -A7: Fluorodopan -A6: Semustine (MeCCNU) ... T1: CPT,20-ester (S) (610456) -T1: CPT,20-ester (S) (606497) -T1: CPT, ...
http://discover.nci.nih.gov/nature2000/paper/fig3.pdf
discover.nci.nih.gov
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summary
Anticancer activity of extracts derived from the mature roots of ...
Combination treatment with S. baicalensis and BCNU ... As expected, 2.5 ?g/ml of BCNU alone had no effect on these cells and 50 ?g/ml ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1560162
www.pubmedcentral.nih.gov
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Adult Brain Tumors
STANDARD TREATMENT OPTIONS: Surgery alone or in conjunction with chemotherapy. ... Carmustine (BCNU)-impregnated polymer may be implanted during surgery.[7,8] ...
http://www.webmd.com/cancer/brain-cancer/tc/brain-tumors-adu...
www.webmd.com
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