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amifostine
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what is 'amifostine'?
Definition for Amifostine - Amifostine
Amifostine is a cytoprotective adjuvant used in cancer chemotherapy involving DNA -binding chemotherapeutic agents. Also commonly known as WR-1065 in its active form. It is marketed by MedImmune under the trade name Ethyol .
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Amifostine is a cytoprotective adjuvant used in cancer chemotherapy involving DNA -binding chemotherapeutic agents. Also commonly known as WR-1065 in its active form. It is marketed by MedImmune under the trade name Ethyol .
Amifostine is used therapeutically to reduce the incidence of neutropenia -related fever and infection induced by DNA-binding chemotherapeutic agents including alkylating agents (e.g. cyclophosphamide ) and platinum-containing agents (e.g. cisplatin ). It is also used to decrease the cumulative nephrotoxicity associated with platinum-containing agents. Amifostine is also indicated to reduce the incidence of xerostomia in patients undergoing radiotherapy for head and neck cancer.
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diagnoses treated with 'amifostine'
1 - 1 of
1
diagnosis
myelodysplasia
ineffective production of blood cells and predisposition to cancer
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Amifostine and myelodysplasia
related procedures when taking 'amifostine'
1 - 5 of
27
procedures
Biopsy bone marrow
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Amifostine and Biopsy bone marrow
Blood, Platelet Count
Platelet Count
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Amifostine and Blood, Platelet Count
Bone Marrow Aspiration
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Amifostine and Bone Marrow Aspiration
CD55 (decay accelerating factor [DAF])
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Amifostine and CD55 (decay accelerating factor [DAF])
CD59 (membrane inhibitor of reactive lysis [MIRL])
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Amifostine and CD59 (membrane inhibitor of reactive lysis [MIRL])
CMV serology
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Amifostine and CMV serology
Central venous catheter
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Amifostine and Central venous catheter
Chromosomal analysis
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Amifostine and Chromosomal analysis
Complete Blood Count
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Amifostine and Complete Blood Count
Epstein Barr Virus serology
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Amifostine and Epstein Barr Virus serology
Fluorescent in situ hybridization (FISH)
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Amifostine and Fluorescent in situ hybridization (FISH)
HLA (human leukocyte antigen)
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Amifostine and HLA (human leukocyte antigen)
Hematopoietic stem cell transplantation
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Amifostine and Hematopoietic stem cell transplantation
Hemoglobin electrophoresis
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Amifostine and Hemoglobin electrophoresis
Histocompatibility testing
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Amifostine and Histocompatibility testing
Human Immunodeficiency Virus (HIV) serology
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Amifostine and Human Immunodeficiency Virus (HIV) serology
Immunosuppressive therapy
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Amifostine and Immunosuppressive therapy
Peripheral blood smear
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Amifostine and Peripheral blood smear
Polymerase Chain Reaction (PCR)
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Amifostine and Polymerase Chain Reaction (PCR)
Reticulocyte count
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Amifostine and Reticulocyte count
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related medication for 'amifostine'
1 - 5 of
9
drugs
azacitidine
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Amifostine and azacitidine
cladribine (2-cda)
web search for:
Amifostine and cladribine (2-cda)
cytosine arabinoside
web search for:
Amifostine and cytosine arabinoside
decitabine
web search for:
Amifostine and decitabine
diepoxybutane (deb)
web search for:
Amifostine and diepoxybutane (deb)
erythropoietin
web search for:
Amifostine and erythropoietin
granulocyte colony-stimulating factor [g-csf])
web search for:
Amifostine and granulocyte colony-stimulating factor [g-csf])
hydroxyurea
web search for:
Amifostine and hydroxyurea
lenalidomide
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Amifostine and lenalidomide
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The following are types of physicians relevant for 'Amifostine'.
related types of physicians 'family practitioner, hematologist, internist, oncologist'
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web search results for 'amifostine'?
Results
1 - 50
- Amifostine
Amifostine - Wikipedia, the free encyclopedia
Common side effects of amifostine include hypocalcemia, diarrhea, nausea, ... Retrieved from "http://en.wikipedia.org/wiki/Amifostine" ...
http://en.wikipedia.org/wiki/Amifostine
en.wikipedia.org
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summary
Amifostine consumer information from Drugs.com
Amifostine patient information. ... For amifostine, the following should be considered: ... Although amifostine has been given to a limited number of elderly ...
http://www.drugs.com/cons/Amifostine.html
www.drugs.com
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Drug Information for Amifostine Crystalline IV - WebMD
Find medical information for Amifostine Crystalline IV including side effects, drug interactions, images and pictures, medication uses, warnings, user ratings and ...
http://www.webmd.com/drugs/drug-1287-Amifostine+Crystalline+...
www.webmd.com
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AMIFOSTINE - INJECTION (Ethyol) side effects, medical uses, and drug ...
Read more about the prescription drug AMIFOSTINE - INJECTION. ... GENERIC NAME: AMIFOSTINE - INJECTION (am-ih-FOSS-teen) BRAND NAME(S): Ethyol ...
http://www.medicinenet.com/amifostine-injection/article.htm
www.medicinenet.com
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Ethyol (Amifostine) Drug Information: Uses, Side Effects, Drug ...
Learn about the prescription medication Ethyol (Amifostine), drug uses, dosage, side effects, drug interactions, warnings, and patient labeling.
http://www.rxlist.com/ethyol-drug.htm
www.rxlist.com
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Amifostine (Intravenous Route) - MayoClinic.com
Mayo Clinic offers award-winning medical and health information and tools for healthy living. ... Amifostine is used to help prevent or lessen some of the side ...
http://www.mayoclinic.com/health/drug-information/DR600067/M...
www.mayoclinic.com
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MedlinePlus Drug Information: Amifostine Injection
Your doctor has ordered the drug amifostine to help treat your illness. ... tell your doctor and pharmacist if you are allergic to amifostine or any other drugs. ...
http://www.nlm.nih.gov/medlineplus/druginfo/meds/a696014.html
www.nlm.nih.gov
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Definition of amifostine - NCI Dictionary of Cancer Terms
The Nation's Investment in Cancer Research FY 2010 ... High Dose Chemotherapy Prolongs Survival for Leukemia ... amifostine ...
http://www.nci.nih.gov/Templates/db_alpha.aspx?CdrID=45250
www.nci.nih.gov
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Amifostine - PubChem Public Chemical Database
PubChem Compound Summary ... Amifostine - Substance Summary (SID 172354) ... ETHYOL (amifostine) is an organic thiophosphate cytoprotective agent known ...
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=172354
pubchem.ncbi.nlm.nih.gov
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Intrarectal Amifostine During External Beam Radiation Therapy for ...
A significant difference between Amifostine groups was observed using the EPIC ... Endorectal administration of Amifostine has been assessed in preclinical and ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2267374
www.pubmedcentral.nih.gov
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Prophylactic use of amifostine to prevent radiochemotherapy-induced ...
Amifostine (300 mg/m(2)) was administered in the study group only 15-30 min ... Furthermore, amifostine reduced the severity of late xerostomia, a side effect ...
http://www.ncbi.nlm.nih.gov/pubmed/11849797?ordinalpos=8&ito...
www.ncbi.nlm.nih.gov
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A pilot study to evaluate the feasibility of using willingness to pay ...
... of value in cancer supportive care: an assessment of amifostine cytoprotection. ... included direct costs for amifostine administration and hospital savings ...
http://gateway.nlm.nih.gov/MeetingAbstracts/ma?f=102233025.html
gateway.nlm.nih.gov
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Eprosartan: Drug Information Provided by Lexi-Comp: Merck Manual ...
Management: When amifostine is used at chemotherapy doses, ... If antihypertensive therapy can not be withheld, amifostine should not be administered. ...
http://www.merck.com/mmpe/print/lexicomp/eprosartan.html
www.merck.com
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Amifostine facts and comparsions at Drugs.com
All about Amifostine. View complete and up to date Amifostine information - part of the Drugs.com trusted medication database.
http://www.drugs.com/cdi/amifostine.html
www.drugs.com
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Images of Amifostine Crystalline IV - WebMD
View pictures of Amifostine Crystalline IV including drug dosages and medical information and advice on prescription drugs, vitamins and over the counter medications.
http://www.webmd.com/drugs/drug-1287-Amifostine+Crystalline+...
www.webmd.com
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AMIFOSTINE - INJECTION (Ethyol) side effects, medical uses, and drug ...
Read doctor-produced health and medical information written for you to make informed decisions ... View All 5 amifostine-injection Doctor's & Expert's Views " ...
http://www.medicinenet.com/amifostine-injection/index.htm
www.medicinenet.com
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summary
Subcutaneous administration of amifostine during fractionated ...
PURPOSE: Amifostine (WR-2721) is an important cytoprotective agent. ... In approximately 5% of patients, amifostine therapy was interrupted due to ...
http://www.ncbi.nlm.nih.gov/pubmed/10829042?ordinalpos=2&ito...
www.ncbi.nlm.nih.gov
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Dexrazoxane - Wikipedia, the free encyclopedia
Effects of dexrazoxane and amifostine on evolution of Doxorubicin cardiomyopathy ... Amifostine. Keratinocyte growth factor. Palifermin. v ? d ? e ...
http://en.wikipedia.org/wiki/Dexrazoxane
en.wikipedia.org
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Maintenance of Manganese Superoxide Dismutase (SOD2)-Mediated Delayed ...
... Induced by Repeated Administration of the Free Thiol Form of Amifostine ... drugs such as WR1065, the free thiol form of amifostine, have been shown ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2384167
www.pubmedcentral.nih.gov
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A novel methodology for insurance based Willingness to Pay studies.
... a randomized clinical trial evaluating a new cytoprotective agent (amifostine) ... Amifostine. Biomedical Research. Canada. Drug Costs. Europe. Female ...
http://gateway.nlm.nih.gov/MeetingAbstracts/ma?f=102193872.html
gateway.nlm.nih.gov
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Amifostine Side Effects | Drugs.com
Comprehensive and accurate Amifostine side effects information for consumers and healthcare professionals. ... side effects for Amifostine may not be reported. ...
http://www.drugs.com/sfx/amifostine-side-effects.html
www.drugs.com
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MedlinePlus Drug Information: Drugs beginning with Wa
Skip navigation. Other drug names: A B C D E F G H I J K L M N O P Q R S T U ... WR-2721 see Amifostine Injection. Wygesic® see Acetaminophen and Propoxyphene ...
http://www.nlm.nih.gov/medlineplus/druginfo/drug_Wa.html
www.nlm.nih.gov
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Amifostine-mediated protection of normal bone marrow from ...
3495-501 Amifostine (US Bioscience, West Conshohocken, PA; Ethyol, WR-2721), a ... Theoretically, Amifostine and the colony-stimulating factors should provide ...
http://www.ncbi.nlm.nih.gov/pubmed/8242582
www.ncbi.nlm.nih.gov
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Definition of amifostine trihydrate - National Cancer Institute Drug ...
amifostine trihydrate. The trihydrate form of a phosphorylated aminosulfhydryl compound. After dephosphorylation of amifostine by alkaline phosphatase to an ...
http://www.nci.nih.gov/Templates/drugdictionary.aspx?CdrID=39741
www.nci.nih.gov
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Rasburicase - Wikipedia, the free encyclopedia
Rasburicase is approved for use by the FDA (and European ... Amifostine. Keratinocyte growth factor. Palifermin. This enzyme-related article is a stub. ...
http://en.wikipedia.org/wiki/Rasburicase
en.wikipedia.org
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Focused Research and Product Development Goals, Medical Countermeasures ...
Medical Countermeasures Against Radiological and Nuclear Threats ... Amifostine, a free radical scavenger, is the only drug currently licensed as a radioprotectant. ...
http://www3.niaid.nih.gov/topics/radnuc/program/FocusedResearchDevelopment.htm
www3.niaid.nih.gov
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Ethyol Official FDA information, side effects and uses.
Accurate, FDA approved Ethyol information for healthcare professionals and ... Ethyol (amifostine) is an organic thiophosphate cytoprotective agent known ...
http://www.drugs.com/pro/ethyol.html
www.drugs.com
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Management of oxaliplatin-induced peripheral neuropathy
Amifostine. Based on the studies of amifostine with cisplatin, its effect has ... Patients were continued on amifostine for as long as improvement was seen. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1661634
www.pubmedcentral.nih.gov
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THE MERCK MANUAL OF GERIATRICS, Ch. 72, Cancer
Amifostine is a chemoprotectant that is beneficial in treating neurotoxicity and ... The clinical usefulness of amifostine and dexrazoxane has not been fully defined. ...
http://www.merck.com/pubs/mm_geriatrics/sec9/ch72.htm
www.merck.com
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[Ethyol (amifostine): application trial in pediatric oncology]
Amifostine was used in 8 children from 3 to 15 yrs of age treated with ... Amifostine was administered every other CHT course in a dose of 750 mg/m2. ...
http://www.ncbi.nlm.nih.gov/pubmed/10731971
www.ncbi.nlm.nih.gov
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Radioprotective Effect of Heat Shock Protein 25 on Submandibular Glands ...
In the case of amifostine-treated rats, no induction of HSP25 or HSP70i was ... Amifostine treatment 30 minutes before radiation restored the glandular weights ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1780208
www.pubmedcentral.nih.gov
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Current role of chemotherapy protectors in cancer treatment.
... of these agents include amifostine (Ethyol), dexrazoxane (Zinecard), mesna ... Amifostine/therapeutic use. Antineoplastic Agents/adverse effects ...
http://www.ncbi.nlm.nih.gov/pubmed/9577052
www.ncbi.nlm.nih.gov
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Folinic acid - Wikipedia, the free encyclopedia
Folinic acid (INN) or leucovorin (USAN), generally administered as calcium ... Amifostine. Keratinocyte growth factor. Palifermin ...
http://en.wikipedia.org/wiki/Folinic_acid
en.wikipedia.org
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duraclon and Amifostine Drug Interactions
duraclon and Amifostine Drug Interactions. Drug-drug and drug-food interactions between duraclon and Amifostine ... GENERALLY AVOID: Amifostine has been ...
http://www.drugs.com/drug-interactions/duraclon_d00044_amifostine_d03868.html
www.drugs.com
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MedlinePlus Drug Information: Drugs beginning with Ga
G-Tuss® (as a combination product containing Hydrocodone and ... Gammagard® S/D see Immune Globulin Intravenous Injection. Gammaphos see Amifostine Injection ...
http://www.nlm.nih.gov/medlineplus/druginfo/drug_Ga.html
www.nlm.nih.gov
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Drug Information for Ethyol IV - WebMD
Find medical information for Ethyol IV including side effects, drug interactions, images and pictures, ... AMIFOSTINE. Be the first to share your ...
http://www.webmd.com/drugs/drug-1324-Ethyol%20IV.aspx?drugid...
www.webmd.com
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A randomized study of very accelerated radiotherapy with and without ...
In the amifostine group, 11/13 of the patients required a feeding tube ... However, the tolerance of this twice daily amifostine schedule was relatively poor. ...
http://www.ncbi.nlm.nih.gov/pubmed/10725619?ordinalpos=8&ito...
www.ncbi.nlm.nih.gov
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Oral mucositis induced by anticancer treatments: physiopathology and ...
Finally, amifostine reduced the frequency of severe esophagitis after chemo ... Guidelines do not recommend amifostine for prevention of oral mucositis except ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1661654
www.pubmedcentral.nih.gov
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Contents o
amifostine (Ethyol) to strengthen. warnings about the possibility of ... using amifostine and are advised. to pay special attention to any ...
http://www.who.int/entity/medicines/publications/newsletter/en/news2003_2.pdf
www.who.int
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Amifostine reduces side effects and improves complete response rate ...
... To evaluate the efficacy of amifostine in diminishing radiotherapy side effects ... RESULTS: The use of amifostine significantly reduced the risk of developing ...
http://www.ncbi.nlm.nih.gov/pubmed/16198504
www.ncbi.nlm.nih.gov
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Radiation Therapy for Cancer: Q & A - National Cancer Institute
A fact sheet that defines the different types of radiation therapy and discusses ... Amifostine (trade name Ethyol®) is the only drug approved by the U.S. Food and ...
http://www.nci.nih.gov/cancertopics/factsheet/Therapy/radiation
www.nci.nih.gov
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DOPamine: Drug Information Provided by Lexi-Comp: Merck Manual Professional
does not endorse and is not responsible for the accuracy of the content, or for ... Alatrofloxacin, aldesleukin, amifostine, amiodarone, atracurium, aztreonam, ...
http://www.merck.com/mmpe/print/lexicomp/dopamine.html
www.merck.com
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Plasmapheresis reverses all side-effects of a cisplatin overdose ? a ...
... recently published study showed that Amifostine is unable to protect patients ... ototoxicity and nephrotoxicity following high-dose Cisplatin and amifostine. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1334209
www.pubmedcentral.nih.gov
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[Use of gammaphos for protecting the brain from delayed radiation damage]
Amifostine/therapeutic use* Animals. Brain/blood supply. Brain/drug effects ... Radiation-Protective Agents. Amifostine. PMID: 3029800 [PubMed - indexed for MEDLINE] ...
http://www.ncbi.nlm.nih.gov/pubmed/3029800
www.ncbi.nlm.nih.gov
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Non-Small Cell Lung Cancer
Chemotherapy employs drugs given orally or by injection to destroy cancer cells ... Amifostine (Ethyol) reduces the risk for kidney damage in patients taking ...
http://adam.about.com/reports/000072_11.htm
adam.about.com
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Squalene Selectively Protects Mouse Bone Marrow Progenitors Against ...
Amifostine represents one of the most well studied and common cytoprotectants in ... The hypotensive property of amifostine precludes treatment of patients on ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2546596
www.pubmedcentral.nih.gov
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User:Luxomni - Wikipedia, the free encyclopedia
He bought it in the hopes of having an automatic typewriter for writing letters ... underwent 37 radiation treatments with Amifostine and nine weeks of chemotherapy. ...
http://en.wikipedia.org/wiki/User:Luxomni
en.wikipedia.org
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Limited cytoprotective effects of amifostine in high-dose radioactive ...
RESULTS: In both amifostine-treated and nontreated groups statistically ... Amifostine pretreatment did not prevent the parenchymal damage to major salivary ...
http://www.ncbi.nlm.nih.gov/pubmed/18341378?ordinalpos=1&ito...
www.ncbi.nlm.nih.gov
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Cancer Medications | Drugs.com
Compare Cancer medications. Comprehensive Cancer drug options for consumers and professionals including user ... generic name: amifostine class: antidotes, ...
http://www.drugs.com/condition/malignant-disease.html
www.drugs.com
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Amifostine protects against cisplatin-induced ototoxicity in children ...
When used, amifostine (600 mg/m(2)/dose) was administered as a ... Amifostine was ... CONCLUSION: Amifostine administered before and during the cisplatin ...
http://www.ncbi.nlm.nih.gov/pubmed/18669462
www.ncbi.nlm.nih.gov
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