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6-mercaptopurine
what is '6-mercaptopurine'?
Definition for 6-mercaptopurine
Mercaptopurine (also called 6-Mercaptopurine, 6-MP or its brand name Purinethol ) is an immunosuppressive drug .
It is a thiopurine . [ 1 ]
It is used to treat leukemia . It is also used for pediatric non-Hodgkin's lymphoma , [ citation needed ] polycythemia vera , [ citation needed ] psoriatic arthritis , [ citation needed ] and inflammatory bowel disease (such as Crohn's Disease and ulcerative colitis ). [ 2 ]
search results for diagnoses treated with '6-mercaptopurine'
1 - 2 of
2
diagnosis
colitis
large bowel inflammation
web search for:
6-mercaptopurine and colitis
inflammatory bowel disease
chronic inflammation of bowel
web search for:
6-mercaptopurine and inflammatory bowel disease
search results for related procedures when taking '6-mercaptopurine'
1 - 5 of
48
procedures
bowel resection
web search for:
6-mercaptopurine and bowel resection
Anti-Saccharomyces cerevisiae antibody (ASCA)
web search for:
6-mercaptopurine and Anti-Saccharomyces cerevisiae antibody (ASCA)
Antineutrophil cytoplasmic antibodies (ANCA)
web search for:
6-mercaptopurine and Antineutrophil cytoplasmic antibodies (ANCA)
Barium Enema
Introducing barium into the colon and rectum for radiologicial viewing of bowel
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6-mercaptopurine and Barium Enema
Biopsy
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6-mercaptopurine and Biopsy
C Reactive Protein (CRP)
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6-mercaptopurine and C Reactive Protein (CRP)
Capsule endoscopy
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6-mercaptopurine and Capsule endoscopy
Colectomy
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6-mercaptopurine and Colectomy
Colonoscopy
Colonoscopy
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6-mercaptopurine and Colonoscopy
Complete Blood Count
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6-mercaptopurine and Complete Blood Count
Complete metabolic panel
web search for:
6-mercaptopurine and Complete metabolic panel
Erythrocyte Sedimentation Rate (ESR)
web search for:
6-mercaptopurine and Erythrocyte Sedimentation Rate (ESR)
Fecal Occult Blood Tests
Test for occult blood in stool
web search for:
6-mercaptopurine and Fecal Occult Blood Tests
Flexible Sigmoidoscopy
Flexible Sigmoidoscopy
web search for:
6-mercaptopurine and Flexible Sigmoidoscopy
Intravenous (IV) fluids
web search for:
6-mercaptopurine and Intravenous (IV) fluids
Intravenous (IV) lactated Ringer (LR) solution
web search for:
6-mercaptopurine and Intravenous (IV) lactated Ringer (LR) solution
Intravenous (IV) normal saline (NS)
web search for:
6-mercaptopurine and Intravenous (IV) normal saline (NS)
KUB
web search for:
6-mercaptopurine and KUB
Partial Resection of Intestine with Anastomosis
web search for:
6-mercaptopurine and Partial Resection of Intestine with Anastomosis
Perinuclear antineutrophil cytoplasmic antibodies (pANCA)
web search for:
6-mercaptopurine and Perinuclear antineutrophil cytoplasmic antibodies (pANCA)
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related medication search results for '6-mercaptopurine'
1 - 5 of
30
drugs
gentamicin
web search for:
6-mercaptopurine and gentamicin
azathioprine
web search for:
6-mercaptopurine and azathioprine
hydrocortisone
web search for:
6-mercaptopurine and hydrocortisone
hydrocortisone(cortef)
web search for:
6-mercaptopurine and hydrocortisone(cortef)
infliximab
web search for:
6-mercaptopurine and infliximab
loperamide
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6-mercaptopurine and loperamide
mesalamine
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6-mercaptopurine and mesalamine
methylprednisolone
web search for:
6-mercaptopurine and methylprednisolone
metronidazole
web search for:
6-mercaptopurine and metronidazole
sulfasalazine(azulfidine)
web search for:
6-mercaptopurine and sulfasalazine(azulfidine)
ampicillin
web search for:
6-mercaptopurine and ampicillin
azathioprine, 6-mercaptopurine
web search for:
6-mercaptopurine and azathioprine, 6-mercaptopurine
cefoxitin
web search for:
6-mercaptopurine and cefoxitin
ceftriaxone
web search for:
6-mercaptopurine and ceftriaxone
chloramphenicol
web search for:
6-mercaptopurine and chloramphenicol
chloramphenicol, colistin, and kanamycin
web search for:
6-mercaptopurine and chloramphenicol, colistin, and kanamycin
clindamycin
web search for:
6-mercaptopurine and clindamycin
erythromycin and ciprofloxacin
web search for:
6-mercaptopurine and erythromycin and ciprofloxacin
iodoquinol or paromomycin
web search for:
6-mercaptopurine and iodoquinol or paromomycin
lactobacillus gg, saccharomyces boulardii
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6-mercaptopurine and lactobacillus gg, saccharomyces boulardii
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The following are types of physicians relevant for '6-mercaptopurine'.
related types of physicians 'family practitioner, gastroenterologist, internist'
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web search results for '6-mercaptopurine'?
Results
1 - 50
- 6-mercaptopurine
Mercaptopurine - Wikipedia, the free encyclopedia
Mercaptopurine. Systematic (IUPAC) name. 3,7-dihydropurine-6-thione ... Mercaptopurine (also called 6-Mercaptopurine, 6-MP or its brand name Purinethol) ...
http://en.wikipedia.org/wiki/6-mercaptopurine
en.wikipedia.org
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Mercaptopurine
Drug details for Mercaptopurine. ... It is sometimes called 6-mercaptopurine, or 6-MP. How It Works ... Mercaptopurine is used to treat acute lymphocytic ...
http://www.webmd.com/cancer/mercaptopurine
www.webmd.com
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Mercaptopurine Official FDA information, side effects and uses.
Accurate, FDA approved Mercaptopurine information for healthcare professionals ... Mechanism of Action: Mercaptopurine (6-MP) competes with hypoxanthine and ...
http://www.drugs.com/pro/mercaptopurine.html
www.drugs.com
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eMedicine - Immunosuppression : Article by Bethany Pellegrino
Immunosuppression after solid organ transplantation is complex. Over the past 50 years, the medical community has ... of 6-mercaptopurine (Purinethol) ...
http://www.emedicine.com/med/topic3558.htm
www.emedicine.com
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summary
Inhibition by 6-Mercaptopurine of Polyarthritis induced by Freund's ...
Prevention of experimental allergic encephalomyelitis with 6-mercaptopurine. ... SCHWARTZ R, STACK J, DAMESHEK W. Effect of 6-mercaptopurine on antibody production. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1030853
www.pubmedcentral.nih.gov
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summary
Azathioprine or 6-mercaptopurine for inducing remi...[Cochrane Database ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... using 6-mercaptopurine in active ...
http://www.ncbi.nlm.nih.gov/pubmed/10796557
www.ncbi.nlm.nih.gov
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Side Effects - Mercaptopurine [Purinethol, 6-MP]
Reference material for Mercaptopurine (also called Purinethol or 6-MP), an immunosuppresive medication that is used in the treatment of Inflammatory Bowel Disease.
http://ibdcrohns.about.com/cs/prescriptiondrugs/p/med6mp.htm
ibdcrohns.about.com
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Mercaptopurine - Yahoo! Health
Mercaptopurine is available as a pill you can swallow. It is sometimes called 6-mercaptopurine, or 6-MP. ... Mercaptopurine is used to treat acute lymphocytic ...
http://health.yahoo.com/digestive-medications/mercaptopurine...
health.yahoo.com
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mercaptopurine - PubChem Public Chemical Database
PubChem Compound Summary ... Laboratories.Mercaptopurine, known ... Drug and Chemical Info from MeSH: (Total:1) 6-Mercaptopurine. Pharmacological Action ...
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=7847229
pubchem.ncbi.nlm.nih.gov
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Information on Crohn's Disease Symptoms, Causes, Diagnosis, and ...
Learn about Crohn's Disease and the causes, symptoms (including abdominal pain, diarrhea, weight loss, fever, ... and 6-mercaptopurine (6-MP, Purinethol) ...
http://www.medicinenet.com/crohns_disease/page11.htm
www.medicinenet.com
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summary
6-mercaptopurine Information from Drugs.com
6-mercaptopurine ... Or browse a complete list of drug names A B C D E F G H I J K L M N O P ... Stedman's > 6-mercaptopurine. 6-mercaptopurine. Pronunciation: ...
http://www.drugs.com/dict/6-mercaptopurine.html
www.drugs.com
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Immunomodulators for inflammatory bowel disease
Drug details for Immunomodulators for inflammatory bowel disease. ... Azathioprine (AZA) and 6-mercaptopurine (6-MP) are used for moderate to severe ...
http://www.webmd.com/ibd-crohns-disease/immunomodulators-for...
www.webmd.com
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The use of 6-mercaptopurine in patients with infla...[Aliment Pharmacol ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... with 6-mercaptopurine and ...
http://www.ncbi.nlm.nih.gov/pubmed/11121903
www.ncbi.nlm.nih.gov
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summary
Definition of mercaptopurine - National Cancer Institute Drug Dictionary
mercaptopurine ... addition, mercaptopurine is converted to 6-methylmercaptopurine ribonucleoside ... 6-thiopurine methyltransferase; MMPRs are also potent ...
http://www.nci.nih.gov/Templates/drugdictionary.aspx?CdrID=43436
www.nci.nih.gov
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Azathioprine - Wikipedia, the free encyclopedia
... he then introduced it as a less toxic replacement for 6-mercaptopurine. ... The enzyme thiopurine S-methyltransferase (TPMT) deactivates 6-mercaptopurine. ...
http://en.wikipedia.org/wiki/Azathioprine
en.wikipedia.org
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Importance of 6-mercaptopurine dose in lymphoblastic leukaemia.
Importance of 6-mercaptopurine dose in lymphoblastic leukaemia. J P Hale and J S ... Their median total dose of 6-mercaptopurine had increased by 22%, whereas ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1792993
www.pubmedcentral.nih.gov
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Purinethol Official FDA information, side effects and uses.
Mercaptopurine, known chemically as 1,7-dihydro-6H-purine-6-thione monohydrate, ... Mercaptopurine (6-MP) competes with hypoxanthine and guanine for the enzyme ...
http://www.drugs.com/pro/purinethol.html
www.drugs.com
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Azathioprine and 6-mercaptopurine pharmacogenetics...[J Gastroenterol ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and other life science journals for biomedical ...
http://www.ncbi.nlm.nih.gov/pubmed/16048561
www.ncbi.nlm.nih.gov
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Treatment of Crohn's disease - Wikipedia, the free encyclopedia
... Mercaptopurine immunosuppressing drugs. 4 Infliximab. 5 Adalimumab. 6 ... Azathioprine or 6-mercaptopurine for inducing remission of Crohn's disease" ...
http://en.wikipedia.org/wiki/Treatment_of_Crohn's_disease
en.wikipedia.org
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Congenital thiopurine methyltransferase deficiency and 6-mercaptopurine ...
Interaction of allopurinol with 6-mercaptopurine and azathioprine. Biomed Pharmacother. ... Is 6-thioguanine more appropriate than 6-mercaptopurine for ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1029622
www.pubmedcentral.nih.gov
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Immunomodulators for inflammatory bowel disease - Yahoo! Health
Immunomodulator medicines, such as azathioprine (AZA), 6-mercaptopurine (6-MP), and methotrexate, weaken or suppress the immune system.
http://health.yahoo.com/digestive-medications/immunomodulato...
health.yahoo.com
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Allergic reactions to 6-mercaptopurine during trea...[J Clin ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... or 6-mercaptopurine-intolerant ...
http://www.ncbi.nlm.nih.gov/pubmed/10372932
www.ncbi.nlm.nih.gov
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Immunosuppressants
... drugs known as immunnosuppressants (Imuran, Cyclosporine, 6-MP, and Methotrexate) including side-effects, ... Mercaptopurine (Purinethol, 6-MP) Side Effects ...
http://ibdcrohns.about.com/od/immunosuppressants/Immunosuppressants.htm
ibdcrohns.about.com
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Preferential inhibition of xanthine oxidase by 2-amino-6-hydroxy-8 ...
The anticancer drug, 6-mercaptopurine (6MP) is subjected to metabolic ... Azathioprine and 6-mercaptopurine alter the nucleotide balance in endothelial cells. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1885804
www.pubmedcentral.nih.gov
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Thiopurine methyltransferase - Wikipedia, the free encyclopedia
Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. ... of the thiopurine drugs such as azathioprine, 6-mercaptopurine and 6-thioguanine. ...
http://en.wikipedia.org/wiki/Thiopurine_methyltransferase
en.wikipedia.org
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6-mercaptopurine in patients with inflammatory bow...[Scand J ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... use of 6-mercaptopurine in patients ...
http://www.ncbi.nlm.nih.gov/pubmed/15841714
www.ncbi.nlm.nih.gov
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Toxic Complications of Treatment with 6-Mercaptopurine
6-Mercaptopurine: effects in mouse sarcoma 180 and in normal animals. Cancer Res. ... The toxic effects of 6-mercaptopurine and related compounds. Ann N Y Acad Sci. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1966646
www.pubmedcentral.nih.gov
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Azathioprine Official FDA information, side effects and uses.
Accurate, FDA approved Azathioprine information for healthcare professionals and patients ... Activation of 6-mercaptopurine occurs via hypoxanthine-guanine ...
http://www.drugs.com/pro/azathioprine.html
www.drugs.com
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Azathioprine and 6-mercaptopurine for the treatmen...[J Clin ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from ... with 6-mercaptopurine/azathioprine for ...
http://www.ncbi.nlm.nih.gov/pubmed/10777191
www.ncbi.nlm.nih.gov
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Gertrude Elion
Gertrude Elion invented the leukemia fighting drug 6-mercaptopurine and drugs that facilitated kidney transplants ... Including 6-mercaptopurine, Getrude ...
http://inventors.about.com/library/inventors/blelion.htm
inventors.about.com
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Acute Leukæmia in Adults Treated with 6-Mercaptopurine
Clinical evaluation of 6-mercaptopurine in the treatment of leukemia. Am J Med Sci. ... James R. Treatment of Leukaemia and Allied Disorders with 6-Mercaptopurine. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1823193
www.pubmedcentral.nih.gov
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6-mercaptopurine
Close Print this page. 6-mercaptopurine. Pronunciation: mer-kap?t?-py?r??n. An analogue of hypoxanthine and of adenine; an antineoplastic agent. ...
http://www.drugs.com/dict/6-mercaptopurine.html?printable=1
www.drugs.com
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Effects of 6-mercaptopurine treatment on sperm pro...[Scand J ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... of 6-mercaptopurine for childbearing ...
http://www.ncbi.nlm.nih.gov/pubmed/16028439
www.ncbi.nlm.nih.gov
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Should TPMT genotype and activity be used to monitor 6-mercaptopurine ...
... TPMT activity cannot be used as an accurate tool for 6-mercaptopurine monitoring. ... 6-Mercaptopurine. Methyltransferases. thiopurine methyltransferase ...
http://www.ncbi.nlm.nih.gov/pubmed/18021342
www.ncbi.nlm.nih.gov
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Leukemia - Wikipedia
User-edited information about leukemia, or leukaemia, the cancer of the blood or bone marrow characterized by an abnormal production of blood cells. Includes types, causes, risk factors, treatments by type, and more.
http://en.wikipedia.org/wiki/Leukemia
en.wikipedia.org
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Metabolism of 6-Mercaptopurine by Resistant Escherichia coli Cells
Reaction of 6-mercaptopurine with inosine- and guanosine-5'-phosphate ... Studies on the mechanism of action of 6-mercaptopurine in cell-free preparations. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=276262
www.pubmedcentral.nih.gov
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The safety of 6-mercaptopurine for childbearing pa...[Gastroenterology ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... of 6-mercaptopurine treatment on ...
http://www.ncbi.nlm.nih.gov/pubmed/12512024
www.ncbi.nlm.nih.gov
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6-Mercaptopurine metabolism in Crohn's disease: correlation with ...
6-Mercaptopurine in the management of inflammatory bowel disease: short ... Long-term experience with 6-mercaptopurine in the treatment of Crohn's disease. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1383347
www.pubmedcentral.nih.gov
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Methotrexate compared with mercaptopurine for earl...[Obstet Gynecol ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE ... 200 mg, 6-mercaptopurine did not induce ...
http://www.ncbi.nlm.nih.gov/pubmed/10362152
www.ncbi.nlm.nih.gov
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Azathioprine and 6-mercaptopurine for maintenance ...[Cochrane Database ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... or 6-mercaptopurine for inducing ...
http://www.ncbi.nlm.nih.gov/pubmed/17253451
www.ncbi.nlm.nih.gov
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6-Mercaptopurine is effective in Crohn's disease without concomitant ...
6-Mercaptopurine is effective in Crohn's disease without concomitant steroids. ... BACKGROUND: 6-Mercaptopurine (6-MP) has shown efficacy in the treatment of ...
http://www.ncbi.nlm.nih.gov/pubmed/15168805
www.ncbi.nlm.nih.gov
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Purine analogue - Wikipedia, the free encyclopedia
It is nonenzymatically cleaved to 6-mercaptopurine that acts as a purine ... Mercaptopurine ... Fludarabine, Mercaptopurine, Pentostatin, Thioguanine) ...
http://en.wikipedia.org/wiki/Purine_analogue
en.wikipedia.org
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Assay of azathioprine, 6-mercaptopurine and a novel thiopurine ...
... method for measuring 6-mercaptopurine in serum. J ... Effect of allopurinol on the pharmacokinetics of 6-mercaptopurine (NSC 755) in cancer patients. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1429803
www.pubmedcentral.nih.gov
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How are Azathioprine and 6-mercaptopurine dosed by...[Inflamm Bowel Dis ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 ... Choice of azathioprine or 6-mercaptopurine dose based on thiopurine ...
http://www.ncbi.nlm.nih.gov/pubmed/18088072?ordinalpos=14&it...
www.ncbi.nlm.nih.gov
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Imuran Official FDA information, side effects and uses.
Accurate, FDA approved Imuran information for healthcare professionals and patients ... Activation of 6-mercaptopurine occurs via hypoxanthine-guanine ...
http://www.drugs.com/pro/imuran.html
www.drugs.com
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summary
Pharmacogenomics and metabolite measurement for 6-...[Gastroenterology ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... 6-mercaptopurine metabolite levels in ...
http://www.ncbi.nlm.nih.gov/pubmed/10734022
www.ncbi.nlm.nih.gov
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Differential effects of 6-mercaptopurine and cyclophosphamide on ...
The effects of 6-mercaptopurine (7·5 mg/kg) and cyclophosphamide (15 mg/kg and ... 6-mercaptopurine administration to NZB mice. Aust J Exp Biol Med Sci. 1968 ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1712938
www.pubmedcentral.nih.gov
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Inflammatory Bowel Syndrome
The term inflammatory bowel syndrome(IBD) covers a group of disorders in which the intestines become inflamed (red ... include 6-mercaptopurine (6-MP, ...
http://www.webmd.com/ibd-crohns-disease/inflammatory-bowel-syndrome?page=5
www.webmd.com
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Selective inhibition of inflammatory gene expressi...[J Pharmacol Exp ...
Azathioprine and 6-mercaptopurine are antimetabolite thiopurine drugs that play ... Azathioprine, 6-mercaptopurine in inflammatory bowel disease: pharmacology, ...
http://www.ncbi.nlm.nih.gov/pubmed/15388785
www.ncbi.nlm.nih.gov
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The role of pharmacogenetics in cancer therapeutics
6-mercaptopurine is used for the treatment of childhood acute lymphocytic leukaemia (ALL) ... Prognostic importance of 6-mercaptopurine dose intensity in acute ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pub...
www.pubmedcentral.nih.gov
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