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5-fluorouracil
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what is '5-fluorouracil'?
Definition for 5-fluorouracil
Fluorouracil (5-FU or f5U) is a pyrimidine analog , which is used as a drug in the treatment of cancer . It belongs to the family of drugs called antimetabolites . It is typically administered with leucovorin .
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Fluorouracil (5-FU or f5U) is a pyrimidine analog , which is used as a drug in the treatment of cancer . It belongs to the family of drugs called antimetabolites . It is typically administered with leucovorin .
The chemotherapy agent 5-FU (fluorouracil), which has been in use against cancer for about 40 years, acts in several ways, but principally as a thymidylate synthase inhibitor . Interrupting the action of this enzyme blocks synthesis of the pyrimidine thymidine , which is a nucleotide required for DNA replication . Thymidylate synthase methylates deoxyuridine monophoshate (dUMP) into thymidine monophosphate (dTMP).
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diagnoses treated with '5-fluorouracil'
1 - 5 of
11
diagnosis
carcinoma pancreas
pancreas cancer
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5-fluorouracil and carcinoma pancreas
vaginal cancer
cancer of vagina
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5-fluorouracil and vaginal cancer
Lynch Syndromes I and II
hereditary nonpolyposis colorectal cancer
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5-fluorouracil and Lynch Syndromes I and II
carcinoid syndrome
symptoms caused by carcinoid tumorsl
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5-fluorouracil and carcinoid syndrome
laryngeal carcinoma
throat cancer
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5-fluorouracil and laryngeal carcinoma
genital warts
warts in genital or anal area
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5-fluorouracil and genital warts
breast cancer in males
cancer of the breast in males
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5-fluorouracil and breast cancer in males
warts
viral infection of skin
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5-fluorouracil and warts
breast cancer in females
cancer of the breast in females
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5-fluorouracil and breast cancer in females
granulosa-theca tumor
benign tumor of ovary
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5-fluorouracil and granulosa-theca tumor
hepatocellular carcinoma
liver cancer
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5-fluorouracil and hepatocellular carcinoma
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related procedures when taking '5-fluorouracil'
1 - 5 of
214
procedures
Biopsy
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5-fluorouracil and Biopsy
CT scan
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5-fluorouracil and CT scan
Chest X-ray
Radiological technique to image the chest
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5-fluorouracil and Chest X-ray
Positron emission tomography (PET)
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5-fluorouracil and Positron emission tomography (PET)
Lymph node biopsy
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5-fluorouracil and Lymph node biopsy
External Beam Radiation
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5-fluorouracil and External Beam Radiation
Radiation Therapy
Use of ionizing radiation or xrays for medical imaging or to treat cancer
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5-fluorouracil and Radiation Therapy
Chemotherapy
Use of chemical substances to treat disease
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5-fluorouracil and Chemotherapy
Brachytherapy
Sealed source radiotherapy
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5-fluorouracil and Brachytherapy
Cytodiagnosis
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5-fluorouracil and Cytodiagnosis
Abdominal CAT Scan
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5-fluorouracil and Abdominal CAT Scan
Laser therapy
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5-fluorouracil and Laser therapy
Needle Biopsy
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5-fluorouracil and Needle Biopsy
Fine Needle Aspiration (FNA) biopsy
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5-fluorouracil and Fine Needle Aspiration (FNA) biopsy
Radical surgery
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5-fluorouracil and Radical surgery
Ultrasound lymph node
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5-fluorouracil and Ultrasound lymph node
Tumor markers
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5-fluorouracil and Tumor markers
Chemoradiotherapy
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5-fluorouracil and Chemoradiotherapy
Intraoperative radiation therapy (IORT)
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5-fluorouracil and Intraoperative radiation therapy (IORT)
Abdominal MRI
MRI of abdominal contents
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5-fluorouracil and Abdominal MRI
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related medication for '5-fluorouracil'
1 - 5 of
31
drugs
cisplatin
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5-fluorouracil and cisplatin
fluorouracil(adrucil )
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5-fluorouracil and fluorouracil(adrucil )
irinotecan
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5-fluorouracil and irinotecan
paclitaxel
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5-fluorouracil and paclitaxel
cisplatin(platinol)
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5-fluorouracil and cisplatin(platinol)
gemcitabine
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5-fluorouracil and gemcitabine
doxorubicin
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5-fluorouracil and doxorubicin
docetaxel
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5-fluorouracil and docetaxel
methotrexate
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5-fluorouracil and methotrexate
capecitabine
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5-fluorouracil and capecitabine
erlotinib
web search for:
5-fluorouracil and erlotinib
erlotinib(tarceva )
web search for:
5-fluorouracil and erlotinib(tarceva )
gemcitabine(gemzar )
web search for:
5-fluorouracil and gemcitabine(gemzar )
oxaliplatin
web search for:
5-fluorouracil and oxaliplatin
imiquimod topical(aldara )
web search for:
5-fluorouracil and imiquimod topical(aldara )
podofilox topical(condylox )
web search for:
5-fluorouracil and podofilox topical(condylox )
trichloroacetic acid
web search for:
5-fluorouracil and trichloroacetic acid
carboplatin
web search for:
5-fluorouracil and carboplatin
etoposide
web search for:
5-fluorouracil and etoposide
actinomycin d
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5-fluorouracil and actinomycin d
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web search results for '5-fluorouracil'?
Results
1 - 50
- 5-fluorouracil
Fluorouracil - Wikipedia, the free encyclopedia
Fluorouracil (5-FU or f5U) is a pyrimidine analog, which is used as a drug in ... The chemotherapy agent 5-FU (fluorouracil), which has been in use against cancer ...
http://en.wikipedia.org/wiki/Fluorouracil
en.wikipedia.org
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summary
fluorouracil topical - Skin Diseases, Conditions, Symptoms, and ...
Information relating to the skin includes skin diseases and conditions, ... cream enhances the effect of 5-fluorouracil by peeling off the top layer of skin. ...
http://www.medicinenet.com/fluorouracil_topical/article.htm
www.medicinenet.com
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summary
Fluorouracil - 5 FU - 5-Fluorouracil ? Chemotherapy for Breast Cancer
Fluorouracil is a chemotherapy drug used in combination with other drugs to treat breast and other cancers. It is also called 5-Fluorouracil, and is part of the FAC ...
http://breastcancer.about.com/od/chemotherapydrugs/p/fluorouracil.htm
breastcancer.about.com
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summary
Fluorouracil
Drug details for Fluorouracil. ... Fluorouracil. Examples. Generic Name. Brand Name. fluorouracil. Adrucil, 5-FU. How It Works ...
http://www.webmd.com/cancer/fluorouracil
www.webmd.com
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summary
5-FLUOROURACIL
Kinetics or entry and distribution of 5-fluorouracil in ... Determination of 5-fluorouracil (NSC-19893) plasma levels in rats and man by isotope ...
http://dohs.ors.od.nih.gov/pdf/5-Fluorouracil%20REVISED.pdf
dohs.ors.od.nih.gov
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summary
5-Fluorouracil - PubChem Public Chemical Database
PubChem Compound Summary ... 5-Fluorouracil - Substance Summary (SID: 9851) ... Chemically, fluorouracil is 5-fluoro-2,4(1H, 3H)-pyrimidinedione. ...
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=9851
pubchem.ncbi.nlm.nih.gov
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summary
5-Fluorouracil-induced cardiotoxicity mimicking myocardial infarction ...
A case of 5-fluorouracil-induced cardiotoxicity, possibly due to coronary artery ... Readministration of 5-fluorouracil is not advised following an episode of ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=60652
www.pubmedcentral.nih.gov
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summary
metronidazole and 5 fu Drug Interactions
... and 5 fu Drug Interactions. Drug-drug and drug-food interactions between metronidazole and 5 fu ... Interactions between metronidazole and 5 fu (fluorouracil) ...
http://www.drugs.com/drug-interactions/metronidazole_d00108_5-fu_d00235.html
www.drugs.com
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summary
Irinotecan plus weekly 5-fluorouracil and leucovor...[Dig Dis. 2007 ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and other life science journals for biomedical ...
http://www.ncbi.nlm.nih.gov/pubmed/17384515
www.ncbi.nlm.nih.gov
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summary
Fluorouracil (5-FU) for nonmelanoma skin cancer
Drug details for Fluorouracil (5-FU) for nonmelanoma skin cancer. ... Fluorouracil (5-FU) is an anticancer medication that works by slowing or stopping cell growth. ...
http://www.webmd.com/melanoma-skin-cancer/fluorouracil-5-fu-...
www.webmd.com
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summary
Irinotecan plus folinic acid/continuous 5-fluorouracil as simplified ...
Keywords: irinotecan, 5-fluorouracil, safety, metastatic colorectal cancer, neoadjuvant ... 5-Fluorouracil (5-FU)-based chemotherapy, ? usually biomodulated ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=49...
www.pubmedcentral.nih.gov
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summary
Carac Official FDA information, side effects and uses.
Accurate, FDA approved Carac information for healthcare professionals and patients ... Chemically, fluorouracil is 5-fluoro-2,4(1H, 3H)-pyrimidinedione. ...
http://www.drugs.com/pro/carac.html
www.drugs.com
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summary
Capecitabine - Wikipedia, the free encyclopedia
... to 5'-DFCR, 5'-DFUR (inactive); neoplastic tissue, 5'-DFUR to active fluorouracil ... that is enzymatically converted to 5-fluorouracil in the tumor, where it ...
http://en.wikipedia.org/wiki/Capecitabine
en.wikipedia.org
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summary
View Study [NEI Clinical Studies]
Clinical Trials Research Tool Supported by the NEI. ... The Fluorouracil Filtering Surgery Study Group recommends the use of subconjunctival 5-FU after ...
http://www.nei.nih.gov/neitrials/viewStudyWeb.aspx?id=21
www.nei.nih.gov
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summary
fluorouracil-injection Glossary of Terms with Definitions on ...
fluorouracil-injection glossary includes a list of fluorouracil-injection ... and to increase the antitumor effects of fluorouracil (5-FU) and tegafur-uracil. ...
http://www.medicinenet.com/fluorouracil-injection/glossary.htm
www.medicinenet.com
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Living with Cancer Chemotherapy
Leucovorin/5-Fluorouracil ... Leucovorin/5-Fluorouracil. How Given: ... Leucovorin/5-Fluorouracil. Special. Instructions: Living with Cancer Chemotherapy Series ...
http://www.cc.nih.gov/ccc/patient_education/CaTxeng/leucov.pdf
www.cc.nih.gov
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summary
5-Fluorouracil/irinotecan induced lethal toxicity as a result of a ...
5FU, 5-fluorouracil. Notes. Full permission was given for this case report ... Dihydropyrimidine dehydrogenase and the efficacy and toxicity of 5-fluorouracil. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1770668
www.pubmedcentral.nih.gov
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summary
5-Fluorouracil (5-FU) and leucovorin in platinum-r...[Gynecol Oncol ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... of 5-fluorouracil and low ...
http://www.ncbi.nlm.nih.gov/pubmed/1526510
www.ncbi.nlm.nih.gov
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summary
Cyclophosphamide Methotrexate Fluorouracil - Wikipedia, the free ...
... cyclophosphamide, methotrexate, 5-fluorouracil (CMF) for ... a b "CMF (cyclophosphamide, methotrexate and 5-fluorouracil)". UK: Breakthrough Breast Cancer. ...
http://en.wikipedia.org/wiki/CMF_(chemotherapy)
en.wikipedia.org
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summary
Leucovorin
Drug details for Leucovorin. ... Fluorouracil: Leucovorin increases the effectiveness of 5-FU, increasing the anticancer effect. ...
http://www.webmd.com/cancer/leucovorin-4309
www.webmd.com
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summary
5 FU - Definition of 5 FU
5-FU (fluorouracil) is a chemotherapy drug that interferes with the growth of cancer cells. ... Learn more about 5-FU by visiting the fluorouracil information page. ...
http://coloncancer.about.com/od/glossaries/g/5_FU.htm
coloncancer.about.com
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summary
Comparative Study Using 5% Imiquimod Cream vs 1% 5-Fluorouracil Cream ...
Comparative Study Using 5% Imiquimod Cream vs 1% 5-Fluorouracil Cream for the ... a new immunomodulator, vs 1% 5-fluorouracil (5-FU) cream for the treatment of GW. ...
http://gateway.nlm.nih.gov/MeetingAbstracts/ma?f=102270507.html
gateway.nlm.nih.gov
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summary
Complete Capecitabine information from Drugs.com
All about Capecitabine. View complete and up to date Capecitabine ... an oral systemic prodrug that is enzymatically converted to 5-fluorouracil (5-FU) ...
http://www.drugs.com/ppa/capecitabine.html
www.drugs.com
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summary
An intravitreal biodegradable sustained release naproxen and 5 ...
5-fluorouracil: New applications in complicated retinal detachment for an ... Adjunct 5-fluorouracil and heparin prevents proliferative vitreoretinopathy: ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1772295
www.pubmedcentral.nih.gov
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summary
Xeloda (Capecitabine) Drug Information: Uses, Side Effects, Drug ...
Learn about the prescription medication Xeloda (Capecitabine), drug uses and information, side effects, drug interactions, ... are allergic to 5-fluorouracil ...
http://www.rxlist.com/cgi/generic/capecitabine.htm
www.rxlist.com
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summary
fluorouracil topical Glossary of Terms with Definitions on MedicineNet.com
fluorouracil topical glossary includes a list of fluorouracil topical related medical definitions ... 5-fluorouracil: An anticancer drug, See: Fluorouracil. ...
http://www.medicinenet.com/fluorouracil_topical/glossary.htm
www.medicinenet.com
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summary
Folinic acid - Wikipedia, the free encyclopedia
It is also used in synergistic combination with the chemotherapy agent 5-fluorouracil. ... the effect of 5-fluorouracil on inhibiting thymidylate synthase. ...
http://en.wikipedia.org/wiki/Folinic_acid
en.wikipedia.org
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summary
Schedule-selective biochemical modulation of 5-fluorouracil in advanced ...
5-fluorouracil remains the standard therapy for patients with advanced ... Ongoing studies evaluating 5-fluorouracil modulation with more novel agents ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=113263
www.pubmedcentral.nih.gov
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summary
FDUR Official FDA information, side effects and uses.
Accurate, FDA approved FDUR information for healthcare professionals and ... In addition, 5-fluorouracil, to which floxuridine is catabolized when given by ...
http://www.drugs.com/pro/fdur.html
www.drugs.com
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summary
Effects of 5-fluorouracil and leucovorin in the tr...[Am J Clin Oncol ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... and 5-fluorouracil plus levo ...
http://www.ncbi.nlm.nih.gov/pubmed/10955877
www.ncbi.nlm.nih.gov
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Docetaxel Improves Survival in Stomach Cancer - National Cancer Institute
Addition of the drug docetaxel (Taxotere®) to other chemotherapy drugs used to treat advanced stomach cancer increased the ... cisplatin and 5-fluorouracil ...
http://www.nci.nih.gov/clinicaltrials/results/docetaxel-and-stomach-cancer0505
www.nci.nih.gov
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summary
Chemoradiotherapy with or without consolidation chemotherapy using ...
CRT with 5-fluorouracil (5-FU) and mitomicin-C (MMC) has also been evaluated in ... results of a phase II trial of high dose radiation therapy, 5-fluorouracil and ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2245963
www.pubmedcentral.nih.gov
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Xeloda Drug Information, Professional
Xeloda Drug Information from Drugs.com. Includes Xeloda side effects, interactions ... (5'-DFUR) and then hydrolyzed to the active substance, fluorouracil, by ...
http://www.drugs.com/mmx/xeloda.html
www.drugs.com
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summary
FOLFOX - Wikipedia, the free encyclopedia
Leucovorin and fluorouracil with or without oxaliplatin as ... HTML PDF Patients with advanced colorectal cancer were given 5-fluorouracil and leukovorin. ...
http://en.wikipedia.org/wiki/FOLFOX
en.wikipedia.org
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Drug Information for Coumadin Oral - WebMD
Find medical information for Coumadin Oral including side effects, drug interactions, images and pictures, ... warfarin and 5-fluorouracil, not between ...
http://www.webmd.com/drugs/drug-4069-Coumadin+Oral.aspx?drug...
www.webmd.com
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summary
Sorivudine and 5-fluorouracil; a clinically significant drug-drug ...
Keywords: sorivudine, 5-fluorouracil, drug interaction, dihydropyrimidine ... Clinical pharmacokinetics of 5-fluorouracil and its metabolites in plasma, urine, ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1873978
www.pubmedcentral.nih.gov
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Leucovorin and fluorouracil vs levamisole and fluo...[Oncol Rep. 2004 ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... of 5-fluorouracil- levamisole does ...
http://www.ncbi.nlm.nih.gov/pubmed/15375524?ordinalpos=3&ito...
www.ncbi.nlm.nih.gov
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summary
Dehalogenation of 5-fluorouracil by Mycobacterium avium.
Dehalogenation of 5-fluorouracil by Mycobacterium avium. ... resistance to the antineoplastic drug, 5-fluorouracil (FUra), and was found to ...
http://gateway.nlm.nih.gov/MeetingAbstracts/ma?f=102226623.html
gateway.nlm.nih.gov
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summary
Benefits of adjuvant therapy for rectal cancer
... a sequential regimen of 5-fluorouracil-based chemotherapy and radiation therapy ... may be achieved using irradiation and standard doses of 5-fluorouracil. ...
http://www.nlm.nih.gov/databases/alerts/rectal_cancer.html
www.nlm.nih.gov
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summary
Treatment of conjunctival squamous cell carcinoma with topical 5 ...
Topical 5-fluorouracil in treating epithelial neoplasia of the conjunctiva and cornea. ... Topical application of 5-fluorouracil in premalignant lesions of ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1723406
www.pubmedcentral.nih.gov
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summary
Breast Cancer
Cyclophosphamide, 5-fluorouracil (5-FU), and methotrexate (CMF) ... the standard regimen of 5-fluorouracil, doxorubicin, and cyclophosphomide (FAC) ...
http://adam.about.com/reports/000006_10.htm
adam.about.com
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summary
Levamisole Hydrochloride Drug Information, Professional
Levamisole Hydrochloride Drug Information from Drugs.com. Includes Levamisole ... Levamisole plus 5-fluorouracil as an adjuvant to surgery for resectable ...
http://www.drugs.com/mmx/levamisole-hydrochloride.html
www.drugs.com
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summary
Nonsurgical treatment of basal cell carcinomas wit...[J Am Acad ...
PubMed is a service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and ... 5-fluorouracil therapeutic ...
http://www.ncbi.nlm.nih.gov/pubmed/8996264
www.ncbi.nlm.nih.gov
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Phase I/II study of first-line irinotecan combined with 5-fluorouracil ...
... of studies using bolus 5-fluorouracil combined with irinotecan, the use ... Until recently, 5-fluorouracil (5-FU) in combination with folinic acid (FA) has ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=493270
www.pubmedcentral.nih.gov
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A sensitive assay of 5-fluorouracil in plasma by gas chromatography ...
2 5-fluorouracil was extracted from plasma by a novel procedure which removed ... Clinical pharmacology of oral and intravenous 5-fluorouracil (NSC-19893) ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1428807
www.pubmedcentral.nih.gov
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Ellence
... epirubicin, 5-fluorouracil continuous infusion, gemcitabine) in stage IV ... Tentas K, Tzivras M, et al. Combined epirubicin, 5-fluorouracil and folinic acid ...
http://www.drugs.com/mmx/ellence.html?printable=1
www.drugs.com
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summary
Oxaliplatin with high-dose leucovorin and 5-fluoro...[Eur J Cancer ...
[Oxaliplatin, folinic acid and 5-fluorouracil (folfox) in pretreated patients ... Bimonthly high-dose leucovorin, 5-fluorouracil infusion and oxaliplatin (FOLFOX3) ...
http://www.ncbi.nlm.nih.gov/pubmed/9135491
www.ncbi.nlm.nih.gov
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Anal Cancer
... approximately 70% of patients surviving 5 or more years in single ... Cummings BJ: The Role of Radiation Therapy With 5-Fluorouracil in Anal Cancer. ...
http://www.webmd.com/colorectal-cancer/tc/anal-cancer-treatm...
www.webmd.com
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Linking uracil base excision repair and 5-fluorouracil toxicity in yeast
( A) The 5-fluorouracil may interfere with nucleic acid structure and function ... Doong S.L., Dolnick B.J. 5-fluorouracil substitution alters pre-mRNA splicing in ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pub...
www.pubmedcentral.nih.gov
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Anticryptococcal activity of SSY726, a new triazole antifungal agent ...
... (CY, 100 mg/kg, i.p.), 5-fluorouracil (5-FU, 150 mg/kg, i.p.) or ... Every four days treatment with 5 mg/kg/day of SSY726 (total dose: 10 mg/kg) ...
http://gateway.nlm.nih.gov/MeetingAbstracts/ma?f=102234848.html
gateway.nlm.nih.gov
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