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what is 'toxic methemoglobinemia - increased levels of methemoglobin caused by toxins '?
Definition for toxic methemoglobinemia
Exposure to exogenous oxidizing drugs and their metabolites (such as benzocaine, dapsone and nitrates) may accelerate the rate of formation of methemoglobin up to one-thousandfold, overwhelming the protective enzyme systems and acutely increasing methemoglobin levels.
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Exposure to exogenous oxidizing drugs and their metabolites (such as benzocaine, dapsone and nitrates) may accelerate the rate of formation of methemoglobin up to one-thousandfold, overwhelming the protective enzyme systems and acutely increasing methemoglobin levels. Other classical drug causes of methaemoglobinaemia include antibiotics (trimethoprim, sulphonamides and dapsone), local anaesthetics (especially lignocaine and prilocaine), and others such as aniline dyes, metoclopramide, chlorates and bromates.
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do i have 'toxic methemoglobinemia'?
In addition the following diagnostic tests might be need to help verify the diagnosis:
diagnostic test search results for 'toxic methemoglobinemia'
1 - 5 of
10
diagnostic tests
Co-oximetry
toxic methemoglobinemia and Co-oximetry
Methemoglobin level
toxic methemoglobinemia and Methemoglobin level
Serum toxicologic screening
toxic methemoglobinemia and Serum toxicologic screening
Pulse oximetry
Oximetry
toxic methemoglobinemia and Pulse oximetry
NADH reductase assay
toxic methemoglobinemia and NADH reductase assay
Potassium cyanide test
toxic methemoglobinemia and Potassium cyanide test
Serum nitrites
toxic methemoglobinemia and Serum nitrites
Arterial Blood Gas
toxic methemoglobinemia and Arterial Blood Gas
Cardiac monitoring
toxic methemoglobinemia and Cardiac monitoring
urine output
toxic methemoglobinemia and urine output
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therapeutic procedures for 'toxic methemoglobinemia'?
Managing or treating a diseases should always be determined by a patients health care provider. Below is a list of associated therapeutic procedures or medications for toxic methemoglobinemia:
therapeutic procedure search results for 'toxic methemoglobinemia'
1 - 3 of
3
therapeutic procedures
rankings are computer generated. please consult your health care provider.
gastric lavage
toxic methemoglobinemia and gastric lavage
exchange transfusion
toxic methemoglobinemia and exchange transfusion
Oxygen
toxic methemoglobinemia and Oxygen
medications search results for 'toxic methemoglobinemia'
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2
medications
rankings are computer generated. please consult your health care provider.
methylene blue
toxic methemoglobinemia and methylene blue
Ascorbic acid
toxic methemoglobinemia and Ascorbic acid
web search results for 'toxic methemoglobinemia'?
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1 - 50
- toxic methemoglobinemia
NASD: Nitrates in Household Water
These bacteria change nitrate into toxic nitrite (NO2) ... This condition is called methemoglobinemia commonly referred to as "blue baby" disease. ...
http://www.cdc.gov/nasd/docs/d001201-d001300/d001233/d001233.html
www.cdc.gov
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Local anesthetic toxicity - Wikipedia, the free encyclopedia
Methemoglobinemia is a process where iron in hemoglobin is altered, reducing its ... Systemic toxic reactions to locally administered anesthetics are progressive as ...
http://en.wikipedia.org/wiki/Local_anesthetic_toxicity
en.wikipedia.org
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Toxicologic Review of Selected Chemicals - 127
... highly toxic, causing cyanosis, kidney irritation, methemoglobinemia, and cancer. ... workers against the significant risks of cyanosis, methemoglobinemia, kidney ...
http://www.cdc.gov/niosh/pel88/101-14.html
www.cdc.gov
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Toxicologic Review of Selected Chemicals - 201
... major toxic effects of dimethylaniline exposure is methemoglobinemia, although ... reported that dimethylaniline is quantitatively less toxic than aniline. ...
http://www.cdc.gov/niosh/pel88/121-69.html
www.cdc.gov
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Documentation for Immediately Dangerous to Life or Health ...
... NDimethylaniline has been reported to be quantitatively less toxic than aniline ... similar effect -- notably, methemoglobinemia [Clayton and Clayton 1981] ...
http://www.cdc.gov/niosh/idlh/121697.html
www.cdc.gov
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Toxicologic Review of Selected Chemicals - 159
... has been reported to be less toxic by ingestion or skin penetration than either ... methemoglobinemia, cyanosis, convulsions, tachycardia, dyspnea, and death ...
http://www.cdc.gov/niosh/pel88/108-46.html
www.cdc.gov
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ICSC:NENG1395 International Chemical Safety Cards (WHO/IPCS/ILO) | CDC ...
The substance decomposes on burning producing toxic gases. ... Similar substances have caused methemoglobinemia, but there are no data ...
http://www.cdc.gov/niosh/ipcsneng/neng1395.html
www.cdc.gov
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Toxicologic Review of Selected Chemicals - 483
... nitrotoluene comparable to aniline in its toxic effects (Linch 1974/Ex. ... against the significant risk of methemoglobinemia, a material health impairment ...
http://www.cdc.gov/Niosh/pel88/88-72.html
www.cdc.gov
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ICSC:NENG1234 International Chemical Safety Cards (WHO/IPCS/ILO) | CDC ...
Gives off irritating or toxic fumes (or gases) in a fire. ... Methemoglobinemia has been observed in animals, but relevance to humans is unclear. ...
http://www.cdc.gov/niosh/ipcsneng/neng1234.html
www.cdc.gov
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Toxicologic Review of Selected Chemicals - 115
... workers against the significant risk of methemoglobinemia and liver damage, ... because this substance is readily absorbed through the skin in toxic amounts. ...
http://www.cdc.gov/niosh/pel88/100-01.html
www.cdc.gov
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Benzocaine: Drug Information Provided by Lexi-Comp: Merck Manual ...
... systemic levels and lead to toxic effects (eg, irregular heart beats, seizures, ... Clinically significant methemoglobinemia requires immediate treatment. ...
http://www.merck.com/mmpe/lexicomp/benzocaine.html
www.merck.com
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Drug Information for Marcaine Inj - WebMD
Toxic Effect on Brain or Spinal Cord Function. Severe. Abnormal Heart Rhythm. Severe ... Methemoglobinemia. Severe. See 6 Reviews for this Drug. - OR - Related ...
http://www.webmd.com/drugs/drug-4081-Marcaine+Inj.aspx?drugi...
www.webmd.com
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Acetanilide - Wikipedia, the free encyclopedia
... than other drugs, causing methemoglobinemia and ultimately doing damage to ... has largely been replaced by less toxic drugs, in particular acetaminophen, ...
http://en.wikipedia.org/wiki/Acetanilide
en.wikipedia.org
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Measurement of Gas Exchange: Tests of Pulmonary Function (PFT): Merck ...
Clinically toxic carboxyhemoglobin levels are most often the result of exposure ... Patients with methemoglobinemia most often have asymptomatic cyanosis. ...
http://www.merck.com/mmpe/sec05/ch046/ch046c.html
www.merck.com
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Talk:Methemoglobinemia - Wikipedia, the free encyclopedia
Actually Methemoglobinemia is caused by drinking water with elevated nitrite-nitrogen levels. ... Para-chloroaniline (PCA) has been shown to be toxic (28, 29) ...
http://en.wikipedia.org/wiki/Talk:Methemoglobinemia
en.wikipedia.org
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CAMPYLOBACTER ENTEROCOLITIS - Pedbase.org
... mesenteric adenitis, pancreatitis, proctitis, rectal hemorrhage, toxic megacolon ... bacteremia (1%), methemoglobinemia. septic and immune-mediated arthritis ...
http://www.pedbase.org/c/campylobacter-enterocolitis
www.pedbase.org
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Metoclopramide: Drug Information Provided by Lexi-Comp: Merck Manual ...
Miscellaneous: Allergic reactions, methemoglobinemia, sulfhemoglobinemia ... Sertraline: Metoclopramide may enhance the adverse/toxic effect of Sertraline. ...
http://www.merck.com/mmpe/print/lexicomp/metoclopramide.html
www.merck.com
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MedlinePlus Medical Encyclopedia: Topics beginning with M-Mf
Skip navigation. Other encyclopedia topics: ... Megarectum see Toxic megacolon. Mehlä hrschaden see Kwashiorkor ... Methemoglobinemia. Methemoglobinemia - acquired ...
http://www.nlm.nih.gov/medlineplus/ency/encyclopedia_M-Mf.htm
www.nlm.nih.gov
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Carbon monoxide poisoning - Wikipedia, the free encyclopedia
... meningitis, methemoglobinemia, or opioid or toxic alcohol poisoning.[38] ... Abatement of toxic levels of carbon monoxide in Seattle ice-skating rinks" ...
http://en.wikipedia.org/wiki/Carbon_monoxide_poisoning
en.wikipedia.org
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Methemoglobinemia in an Infant -- Wisconsin, 1992
Methemoglobinemia among infants is a rare and potentially fatal condition caused ... Toxic responses of the blood. In: Klaassen CD, Amdur MO, Doull J, eds. ...
http://www.cdc.gov/mmwR/preview/mmwrhtml/00020077.htm
www.cdc.gov
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Sulfamethoxazole and Trimethoprim: Drug Information Provided by Lexi ...
... megaloblastic anemia, methemoglobinemia, neutropenia, thrombocytopenia ... Amantadine: Trimethoprim may enhance the adverse/toxic effect of Amantadine. ...
http://www.merck.com/mmpe/print/lexicomp/sulfamethoxazole%20...
www.merck.com
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Gyromitra esculenta - Wikipedia, the free encyclopedia
Methemoglobinemia may also occur in some cases. ... Toxic fungi" ... Amelioration of toxic effects of ethylidene gyromitrin (false morel poison) with ...
http://en.wikipedia.org/wiki/Gyromitra_esculenta
en.wikipedia.org
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Drug Information for Xylocaine in 7.5 % Glucose Inj - WebMD
Toxic Effect on Brain or Spinal Cord Function. Severe. Double Vision. Severe. Slow Heartbeat ... Methemoglobinemia. Severe. Confused. Severe. Drowsiness. Less ...
http://www.webmd.com/drugs/drug-15926-Xylocaine%20in%20Gluco...
www.webmd.com
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Documentation for Immediately Dangerous to Life or Health ...
... for 6 weeks resulted in methemoglobinemia and slight anemia [Watrous and Schultz ... Toxicometric parameters of industrial toxic chemicals under single exposure. ...
http://www.cdc.gov/niosh/idlh/100005.html
www.cdc.gov
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Methylene blue - Wikipedia, the free encyclopedia
Methemoglobinemia: an industrial outbreak among rubber molding ... Toxic metals (cadmium, mercury, lead, thallium) Edetates · Dimercaprol # · Prussian blue ...
http://en.wikipedia.org/wiki/Methylene_blue
en.wikipedia.org
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Nitrate - Wikipedia, the free encyclopedia
Methemoglobinemia can be treated with methylene blue, which reduces ferric iron ... While nitrate is much less toxic than ammonia or nitrite,[6] levels over 30 ppm ...
http://en.wikipedia.org/wiki/Nitrate
en.wikipedia.org
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Drug Information for Sensorcaine-MPF Spinal Inj - WebMD
Toxic Effect on Brain or Spinal Cord Function. Severe. Abnormal Heart ... Methemoglobinemia. Severe. Be the first to share your experience with this drug. ...
http://www.webmd.com/drugs/drug-75372-Sensorcaine-MPF+Spinal...
www.webmd.com
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Methemoglobinemia due to Occupational Exposure to Dinitrobenzene ...
Methemoglobinemia due to Occupational Exposure to Dinitrobenzene -- Ohio, 1986 ... of exposure to these substances as well as to toxic substances in general. ...
http://www.cdc.gov/mmwr/preview/mmwrhtml/00000038.htm
www.cdc.gov
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Nitrogen cycle - Wikipedia, the free encyclopedia
While not directly toxic to fish life like ammonia, nitrate can have indirect ... water is the development of methemoglobinemia and has been found to cause ...
http://en.wikipedia.org/wiki/Nitrogen_cycle
en.wikipedia.org
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The Emergency Response Safety and Health Database: Glossary
A substance produced by a living organism, such as a plant or fish, that has toxic effects. ... Methemoglobinemia. Excessive accumulation of an inactive form ...
http://www.cdc.gov/NIOSH/ershdb/glossary.html
www.cdc.gov
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Antidote - Wikipedia, the free encyclopedia
... that cause methemoglobinemia. Naloxone hydrochloride. opioid ... Toxic metals (cadmium, mercury, lead, thallium) Edetates · Dimercaprol # · Prussian blue ...
http://en.wikipedia.org/wiki/Antidote
en.wikipedia.org
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Documentation for Immediately Dangerous to Life or Health ...
Methemoglobinemia and methemoglobinproducing compounds. Pharmacol Rev 3:144195. ... In: Registry of toxic effects of chemical substances, 1976 ed. Cincinnati, OH: ...
http://www.cdc.gov/niosh/idlh/10102439.html
www.cdc.gov
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The International Conference On Occupational And Environmental ...
There are hundreds of compounds designed to be toxic to insects. ... A very toxic organic mercury, ... i. Benzocaine ointment causes methemoglobinemia. ...
http://www.cdc.gov/niosh/topics/skin/conference/s1t2.html
www.cdc.gov
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Potassium nitrate (data page) - Wikipedia, the free encyclopedia
... being converted to the more toxic nitrites have been reported, mostly with infants. ... Under some circumstances methemoglobinemia occurs in individuals ...
http://en.wikipedia.org/wiki/Potassium_nitrate_(data_page)
en.wikipedia.org
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Drug Information for Septra DS Oral - WebMD
Toxic Epidermal Necrolysis. Severe. Stevens-Johnson Syndrome. Severe. Rare side effects: ... Methemoglobinemia. Severe. Blood Disorder. Severe. Depression ...
http://www.webmd.com/drugs/drug-15726-Septra+DS+Oral.aspx?dr...
www.webmd.com
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Dapsone - Wikipedia, the free encyclopedia
... (which may lead to hemolytic anemia) and methemoglobinemia.[7] ... Toxic hepatitis and cholestatic jaundice have been reported by the manufacturer. ...
http://en.wikipedia.org/wiki/Dapsone
en.wikipedia.org
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Nitrates in Household Water
bacteria change nitrate into toxic nitrite (NO2) ... methemoglobinemia commonly referred to as "blue baby" disease. ... that convert nitrate to toxic nitrite. ...
http://www.cdc.gov/nasd/docs/d001201-d001300/d001233/d001233.pdf
www.cdc.gov
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Pancytopenia - Wikipedia, the free encyclopedia
Alimentary Toxic Aleukia (ATA) [edit] See also. Leukopenia, a reduction in white blood cells ... Other. Methemoglobinemia · Sulfhemoglobinemia ...
http://en.wikipedia.org/wiki/Pancytopenia
en.wikipedia.org
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Isosorbide Mononitrate: Drug Information Provided by Lexi-Comp: Merck ...
... upper respiratory tract infection, arthralgia, methemoglobinemia (rare, overdose) ... (Organic Nitrates) may enhance the adverse/toxic effect of Rosiglitazone. ...
http://www.merck.com/mmpe/print/lexicomp/isosorbide%20mononitrate.html
www.merck.com
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Drug Information for Shocaine W/Epinephrine Inj - WebMD
Toxic Effect on Brain or Spinal Cord Function. Severe. Double Vision. Severe ... Methemoglobinemia. Severe. Confused. Severe. Dry Mouth. Less Severe ...
http://www.webmd.com/drugs/drug-58048-Shocaine+W%2FEpinephri...
www.webmd.com
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Primaquine: Drug Information Provided by Lexi-Comp: Merck Manual ...
... effects: Anemia, methemoglobinemia, and leukopenia have ... Mefloquine: Aminoquinolines (Antimalarial) may enhance the adverse/toxic effect of Mefloquine. ...
http://www.merck.com/mmpe/print/lexicomp/primaquine.html
www.merck.com
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Antidote - Wikipedia, the free encyclopedia
Toxic metal (Lead · Mercury · Cadmium · Antimony · Arsenic · Beryllium · Iron ... Methemoglobinemia poisoning is given methylene blue as the antidote. ...
http://en.wikipedia.org/wiki/Counterpoison
en.wikipedia.org
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Epidemiologic Notes and Reports Methemoglobinemia in an Infant ...
... Services, of methemoglobinemia associated with ingestion ... of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease ...
http://www.cdc.gov/mmwr/PDF/wk/mm4212.pdf
www.cdc.gov
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Neutrophilia - Wikipedia, the free encyclopedia
In a severe infection, toxic granulation changes happen to the neutrophils. ... Other. Methemoglobinemia · Sulfhemoglobinemia · Reticulocytopenia. Coagulation ...
http://en.wikipedia.org/wiki/Neutrophilia
en.wikipedia.org
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EPHI Project: Topics and Types: Health Effect Indicators | CDC EPHI
Morbidity and mortality associated with toxic substances (optional) ... Methemoglobinemia (core) Pesticide-related poisoning and illness (core) ...
http://www.cdc.gov/nceh/indicators/healthEffect.htm
www.cdc.gov
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Propylene glycol dinitrate - Wikipedia, the free encyclopedia
Its primary toxicity mechanism is methemoglobinemia. It may cause permanent nerve damage. ... of its burning is a highly toxic cyanide gas. [edit] References ...
http://en.wikipedia.org/wiki/Propylene_glycol_dinitrate
en.wikipedia.org
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HHE Report No. HETA-86-0350-1815, Barr Rubber Corporation, Sandusky, Ohio
... methemoglobin, methemoglobinemia, cyanosis, ... on the toxic effects of an agent ... shoes may cause toxic symptoms.(13) As shown in Table #I, ...
http://www.cdc.gov/niosh/hhe/reports/pdfs/1986-0350-1815.pdf
www.cdc.gov
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Fertilizer - Wikipedia, the free encyclopedia
... methemoglobinemia), leading to hypoxia (which can lead to coma and death if not treated)[31] ... http://www.mindfully.org/Farm/Toxic-Waste-Fertilizers.htm ...
http://en.wikipedia.org/wiki/Fertilizer
en.wikipedia.org
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Cyclophosphamide: Drug Information Provided by Lexi-Comp: Merck Manual ...
Etanercept: May enhance the adverse/toxic effect of Cyclophosphamide. ... Hematologic: Methemoglobinemia. Neuromuscular & skeletal: Rhabdomyolysis ...
http://www.merck.com/mmpe/lexicomp/cyclophosphamide.html
www.merck.com
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Macrocytic anemia - Wikipedia, the free encyclopedia
... deficiency), apparently as a direct toxic effect of alcohol specifically on the bone marrow. ... Other. Methemoglobinemia · Sulfhemoglobinemia ...
http://en.wikipedia.org/wiki/Macrocytic_anemia
en.wikipedia.org
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